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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Antimalarial

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
NARDISINONE IC50=1.4 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
NARDOPEROXIDE IC50=1.4 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
NB-METHYLAFFINISINE IC50=5->5 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
NEUROLENIN-A IC50=0.9 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
NEUROLENIN-B IC50=0.6 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
NEUROLENIN-C/D IC50=0.6 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
NIMBANDIOL IC50=50 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
NIMBIN IC50=50 ug/ml *
NIMBININ IC50=0.77 ug/ml *
NIMBOLIDE IC50=1.74 ug/mL *
NIMBOLIDE IC50=0.001 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
NIMOCINOL IC50=50 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
NOR-TILIACORINE-A IC50=0.56 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
NORFLUOROCURARINE IC50=129 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
NORTILIACORININE-A *
NYASOL IC50=12 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
O-METHYLEXOSTEMIN IC50=1.6-3.6 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
O-METHYLMACRALSTONINE IC50=0.9 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
OBAMEGINE IC50=0.51 ug/ml (1/4 x chloroquine) *
OLEANOLIC-ACID IC50=70-89 ug/ml *
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Arbutus unedo Arbutus; Strawberry Tree 5 0
Arctium lappa Gobo; Great Burdock; Burdock 2 0
Arctostaphylos uva-ursi Bearberry; Uva Ursi 7 25, 909
Ardisia japonica Marlberry 1 0
Argemone mexicana Prickly Poppy 1 820
Armoracia rusticana Horseradish 1 0
Artemisia abrotanum Southernwood 2 0
Artemisia absinthium Wormwood 2 60
Artemisia annua Qinghao; Sweet Annie; Annual Mugwort (GRIN); Annual Wormwood (GRIN); Sweet Wormwood (GRIN) 15 309, 175
Artemisia capillaris Capillary Wormwood 1 0
Artemisia dracunculus Tarragon 4 560
Artemisia herba-alba Desert Wormwood 3 0
Artemisia indica 4 155
Artemisia salsoloides 3 10, 150
Artemisia vulgaris Mugwort 1 0
Artocarpus altilis Breadfruit 1 0
Artocarpus heterophyllus Jackfruit 2 0
Artocarpus integrifolia 1 3, 000
Arundo donax Giant Reed 1 0
Asimina triloba Pawpaw 2 0