Mahonia repens | Plant | Dr. Duke's Phytochemical and Ethnobotanical Databases

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Common name(s)

Creeping Barberry, Oregon Barberry, Oregon Grape, Oregon Grape-Holly

How used

Medicinal

Data Views

Activities: 209

Chemicals w/Activities: 26

All Chemicals: 28

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List of all chemical
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# Activity	Chemical Name	Part Filter by plant part	Low PPM	High PPM	StdDev	^*Reference
0	(+)-CORYDINE	Leaf	--	540.0	--	*
1	(+)-GLAUCINE	Leaf	--	54.0	--	*
Aldose-Reductase-Inhibitor 50 uM Kubo, M., et al. 1994. Studies on Anti-cataract Drugs from Natural Sources. I. Effects of a Methanolic Extract and the Alkaloidal Components from Corydalis Tuber on in vit Aldose Reductase Activity. Biol Pharm Bull, 17(3): 458-459.
5	(+)-ISOCORYDINE	Leaf	--	1081.0	--	*
Analgesic * Antiarrhythmic * Antihistaminic * Antispasmodic * Vasodilator *
1	5'-METHOXYHYDNOCARPIN	Plant	--	--	--	*
MDR-Inhibitor Stermitz, F. R., Lorenz, P., Tawara, J. N., Zenewicz, L. A., Lewis, K. 2000. Synergy in a medicinal plant: antimicrobial action of berberine potentiated by 5'-methoxyhydnocarpin, a multidrug pump inhibitor. Proc Natl Acad Sci USA, 97(4): 1433-1437.
130	BERBERINE	Root	--	1417.0	-1.19	*
(+)-Inotropic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Abortifacient * Adrenolytic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Amebicide EC83=100 ug/ml orl rat Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Amebicide 200 ug/ml Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Analgesic * Anesthetic * Antiacetylcholinesterase * Antiacne Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Antiadrenergic Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. Antiaggregant * Antialzheimeran * Antiamnesic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Antiangiogenic * Antiarrhythmic * Antiarthritic * Antibacillus MIC=200 ug/ml * Antibacterial 100 mg/4x/day * Antibacterial MIC=6-630 ug/ml * Antibacterial 12.5-2,500 ug/ml Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antibiotic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Anticancer * Anticariogenic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Antichlamydial * Anticholecystitic 5-20 mg/3x/day/orl Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Anticholera 150 mg/man/day Martindale's 28th Anticirrhotic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Anticonjunctivitic 0.20% Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Anticonvulsant Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Antidiarrheic 100 mg/4x/day * Antidysenteric 100 mg/4x/day * Antiedemic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Antiendotoxic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp. Antienterotoxic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antiesherichic * Antigiardial 10 mg/kg/day * Antiglaucomic * Antigonorrhea * Antihepatomic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Antihepatotic * Antiherpetic * Antihistaminic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp. Antiinflammatory * Antiischemic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Antileishmanic 10 ug/ml * Antilipogenic IC63=10 uM Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Antimalarial 0.14-0.36 ug/ml * Antimalarial 50 uM * Antimitotic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Antimuscarinic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp. Antimyalgic * Antimycotic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Antineoplastic * Antinephritic * Antiperistaltic Bruneton, J. 1999. Pharmacognosy, Phytochemistry, Medicinal Plants. 2nd Ed. Lavoisier Publishing, Paris. 1119 pp. Antipharyngitic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antiphotooxidative * Antiplasmodial IC50=0.14-0.36 ug/ml * Antipneumonic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antipyretic 3 x aspirin * Antisalmonella * Antisecretory * Antiseptic 25 ug/ml * Antishigellic 12.5 ug/ml Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antispasmodic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antispermigenic * Antistaphylococcic * Antistrep Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antisyphilitic * Antitrachomic 0.20% * Antitrypanosomic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Antitubercular MIC=25 ug/ml * Antitumor (brain) IC91=150 ug/ml Werbach & Murray, 1994. Antiulcer * Antivaginitic Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. Antiviral Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. Astringent * Bilirubinolytic * Calcium-Antagonist Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Candidicide * Cardiodepressant Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. Cardiotonic * Carminative Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp. Cholagogue * Cholekinetic * Choleretic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Collyrium * COX-2-Inhibitor 100 ug/ml * Cyclooxygenase-Inhibitor * Cytotoxic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Digestive * Diuretic * Emetic * Fungicide 12.5-150 ug/ml Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Glaucomagenic * Hemostat * Hypocholesterolemic Ivorra, M.D., Paya, M., and Villar, A. 1989. A Review of Natural Products and Plants as Potential Antidiabetic Drugs. Journal of Ethnopharmacology, 27: 243-275, 1989. Hypoglycemic * Hypotensive * Immunostimulant * Lachrymatory Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Larvicide 9 ppm * Leucocytogenic * Lipase-Inhibitor Medline (post 1990 searches filed in my computer) Lipoxygenase-Inhibitor IC50=118 uM * Mutagenic * Mycobactericide MIC=25-50 ug/ml * Mydriatic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Myocardiodepressant * Myorelaxant * Pesticide * Phototoxic 9 ppm * Plasmodicide IC50=0.14-0.36 ug/ml * Prostaglandin-Synthesis-Inhibitor 25 mg/kg ivn rbt Huang, C. G., Chu, Z. L., Yang, Z. M. 1991. Effect of Berberine on Synthesis of Platelet TXA2 and Plasma PGI2 in Rabbits. Chung-Kuo Yao Li Hsueh Pao, 12(6): 526-528. Protisticide IC50=0.14-0.36 ug/ml * Respiradepressant Martindale's 28th RNA-Depressant * RT-Inhibitor * Sedative * Stomachic * Topoisomerase-II-Inhibitor 2.5 uM Kobayashi, Y, Yamashita, Y., Fujii, N., Takaboshi, K., Kawakami, T., Kawamura, M., Mizukami, T., Nakano, H. 1995. Inhibitors of DNA Topoisomerase I and II Isolated From the Coptis Rhizomes. Planta Medica, 61: 414-418. Trichomonicide Martindale's 29th Trypanocide * Uterocontractant * Uterotonic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Vagostimulant man * Vasoconstrictor * Vasodilator 2 mg/kg cat * Vermifuge * Vibriofuge *
130	BERBERINE	Stem	--	--	--	Suess, T. R. and Stermitz, F. R. 1981. The Constituents of Castilleja rhexifolia, Mahonia repens and Oncidium cebolleta. Dissertation Abstract Int B, 42: 1025-1026.
(+)-Inotropic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Abortifacient * Adrenolytic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Amebicide EC83=100 ug/ml orl rat Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Amebicide 200 ug/ml Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Analgesic * Anesthetic * Antiacetylcholinesterase * Antiacne Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Antiadrenergic Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. Antiaggregant * Antialzheimeran * Antiamnesic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Antiangiogenic * Antiarrhythmic * Antiarthritic * Antibacillus MIC=200 ug/ml * Antibacterial 100 mg/4x/day * Antibacterial MIC=6-630 ug/ml * Antibacterial 12.5-2,500 ug/ml Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antibiotic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Anticancer * Anticariogenic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Antichlamydial * Anticholecystitic 5-20 mg/3x/day/orl Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Anticholera 150 mg/man/day Martindale's 28th Anticirrhotic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Anticonjunctivitic 0.20% Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Anticonvulsant Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Antidiarrheic 100 mg/4x/day * Antidysenteric 100 mg/4x/day * Antiedemic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Antiendotoxic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp. Antienterotoxic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antiesherichic * Antigiardial 10 mg/kg/day * Antiglaucomic * Antigonorrhea * Antihepatomic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Antihepatotic * Antiherpetic * Antihistaminic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp. Antiinflammatory * Antiischemic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Antileishmanic 10 ug/ml * Antilipogenic IC63=10 uM Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Antimalarial 0.14-0.36 ug/ml * Antimalarial 50 uM * Antimitotic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Antimuscarinic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp. Antimyalgic * Antimycotic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Antineoplastic * Antinephritic * Antiperistaltic Bruneton, J. 1999. Pharmacognosy, Phytochemistry, Medicinal Plants. 2nd Ed. Lavoisier Publishing, Paris. 1119 pp. Antipharyngitic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antiphotooxidative * Antiplasmodial IC50=0.14-0.36 ug/ml * Antipneumonic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antipyretic 3 x aspirin * Antisalmonella * Antisecretory * Antiseptic 25 ug/ml * Antishigellic 12.5 ug/ml Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antispasmodic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antispermigenic * Antistaphylococcic * Antistrep Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antisyphilitic * Antitrachomic 0.20% * Antitrypanosomic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Antitubercular MIC=25 ug/ml * Antitumor (brain) IC91=150 ug/ml Werbach & Murray, 1994. Antiulcer * Antivaginitic Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. Antiviral Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. Astringent * Bilirubinolytic * Calcium-Antagonist Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Candidicide * Cardiodepressant Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. Cardiotonic * Carminative Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp. Cholagogue * Cholekinetic * Choleretic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Collyrium * COX-2-Inhibitor 100 ug/ml * Cyclooxygenase-Inhibitor * Cytotoxic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Digestive * Diuretic * Emetic * Fungicide 12.5-150 ug/ml Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Glaucomagenic * Hemostat * Hypocholesterolemic Ivorra, M.D., Paya, M., and Villar, A. 1989. A Review of Natural Products and Plants as Potential Antidiabetic Drugs. Journal of Ethnopharmacology, 27: 243-275, 1989. Hypoglycemic * Hypotensive * Immunostimulant * Lachrymatory Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Larvicide 9 ppm * Leucocytogenic * Lipase-Inhibitor Medline (post 1990 searches filed in my computer) Lipoxygenase-Inhibitor IC50=118 uM * Mutagenic * Mycobactericide MIC=25-50 ug/ml * Mydriatic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Myocardiodepressant * Myorelaxant * Pesticide * Phototoxic 9 ppm * Plasmodicide IC50=0.14-0.36 ug/ml * Prostaglandin-Synthesis-Inhibitor 25 mg/kg ivn rbt Huang, C. G., Chu, Z. L., Yang, Z. M. 1991. Effect of Berberine on Synthesis of Platelet TXA2 and Plasma PGI2 in Rabbits. Chung-Kuo Yao Li Hsueh Pao, 12(6): 526-528. Protisticide IC50=0.14-0.36 ug/ml * Respiradepressant Martindale's 28th RNA-Depressant * RT-Inhibitor * Sedative * Stomachic * Topoisomerase-II-Inhibitor 2.5 uM Kobayashi, Y, Yamashita, Y., Fujii, N., Takaboshi, K., Kawakami, T., Kawamura, M., Mizukami, T., Nakano, H. 1995. Inhibitors of DNA Topoisomerase I and II Isolated From the Coptis Rhizomes. Planta Medica, 61: 414-418. Trichomonicide Martindale's 29th Trypanocide * Uterocontractant * Uterotonic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Vagostimulant man * Vasoconstrictor * Vasodilator 2 mg/kg cat * Vermifuge * Vibriofuge *
77	CHLOROGENIC-ACID	Leaf	--	--	--	Grace, S. C., Logan, B. A., Adams III, W. W. 1998. Seasonal Differences in Foliar Content of Chlorogenic Acid, a Phenylpropanoid Antioxidant, in Mahonia repens. Plant Cell Environ, 21(5): 513-521.
Aldose-Reductase-Inhibitor IC50=1.8 uM rat (strong activity) Yoshikawa, M., et al. 1999. Medicinal Flowers. I. Aldose Reductase Inhibitors and Three New Eudesmane-Type Sesquiterpenes, Kikkanols A, B, and C, From the Flowers of Chrysanthemum inducum L. Chem Pharm Bull, 47(3): 340-345. Allelochemic * Allergenic * Analgesic * Antiatherosclerotic * Antibacterial * Anticancer (Colon) * Anticancer (Forestomach) * Anticancer (Liver) * Anticancer (Skin) * Anticarcinogenic * Antidiabetic * AntiEBV Economic & Medicinal Plant Research, 6: 189. Antifeedant * Antigenotoxic * Antigonadotropic Jim Duke's personal files. Antihemolytic 10 uM Ohnishi, M., Morishita, H., Iwahashi, H., Toda, S., Shirataki, Y., Kimura, M., and Kido, R. 1993. Inhibitory Effects of Chlorogenic Acids on Linoleic Acid Peroxidation and Haemolysis. Phytochemistry. 36(3): 579-583. 1994. Antihepatotoxic * Antiherpetic Economic & Medicinal Plant Research, 5: 194. Antihistaminic * AntiHIV Economic & Medicinal Plant Research, 6: 189. Antihypercholesterolemic Economic & Medicinal Plant Research, 6: 189. Antihyperthyroid * Antiinflammatory Hagerman, A.E. Tannin-Protein Interactions. Phenolic Compounds in Food and Their Effects on Health, Ch.19. AntiLegionella * Antileukotriene * Antimelanogenic * Antimutagenic * Antinitrosaminic * Antioxidant IC53=200 ppm Huang, M-T., and Ferraro, T. Phenolic Compounds in Food and Cancer Prevention. Phenolic Compounds in Food and Their Effects on Health, Ch.2 p.21. Antioxidant IC80=12 uM * Antioxidant IC50=54.2 uM * Antiperoxidant IC50=36 uM Planta Medica, 57: A54, 1991. Antipolio Jim Duke's personal files. Antiradicular 9 x quercetin * Antiradicular 10 uM Ohnishi, M., Morishita, H., Iwahashi, H., Toda, S., Shirataki, Y., Kimura, M., and Kido, R. 1993. Inhibitory Effects of Chlorogenic Acids on Linoleic Acid Peroxidation and Haemolysis. Phytochemistry. 36(3): 579-583. 1994. Antiseptic * Antisunburn * Antithyroid Jim Duke's personal files. Antitumor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antitumor (Colon) * Antitumor (Forestomach) * Antitumor (Liver) * Antitumor (Skin) * Antitumor-Promoter IC25=10 uM * Antiulcer Economic & Medicinal Plant Research, 6: 189. Antiviral Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart. Autotoxic * Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Cardioprotective * Chemopreventive * Cholagogue Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp. Choleretic Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. Clastogenic Friedman, M. and Dao, L. 1990. Effect of Autoclaving and Conventional and Microwave Baking on the Ergot Alkaloid and Chlorogenic Acid Contents of Morning Glory (Ipomoea tricolor Cav. cv.) Heavenly Blue Seeds. J. Agric. Food Chem. 38: 805-808. CNS-Active Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp. CNS-Stimulant 1/6 Caffeine * Collagen-Sparing * Diuretic * Fungicide Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp. Hepatoprotective Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. Histamine-Inhibitor * Hypoglycemic * Immunostimulant * Insectifuge Tunon, H., Thorsell, W., and Bohlin, L. 1993. Mosquito Repelling Activity of Compounds Occurring in Achillea millefolium L. (Asteraceae). Economic Botany 48(2): 111-120, 1994. Interferonogenic Economic & Medicinal Plant Research, 1: 124. Juvabional Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Larvistat Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Leukotriene-Inhibitor * Lipoxygenase-Inhibitor IC23=5 mM Oszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690. Metal-Chelator McEvily, A.J., Iyengar, R., and Gross, A.T. Inhibition of Polyphenol Oxidase by Phenolic Compounds. Phenolic Compounds in Food and Their Effects on Health, Ch.25. NO-Genic * Ornithine-Decarboxylase-Inhibitor Hagerman, A.E. Tannin-Protein Interactions. Phenolic Compounds in Food and Their Effects on Health, Ch.19. Oviposition-Stimulant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Pesticide * Sunscreen * Sweetener Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. Vulnerary *
7	COLUMBAMINE	Root	--	28.0	--	*
Antibacterial * Antimalarial 0.72 ug/ml * Choleretic * CNS-Depressant * Enterotonic * Hypotensive * Pesticide *
7	COLUMBAMINE	Stem	--	--	--	Suess, T. R. and Stermitz, F. R. 1981. The Constituents of Castilleja rhexifolia, Mahonia repens and Oncidium cebolleta. Dissertation Abstract Int B, 42: 1025-1026.
Antibacterial * Antimalarial 0.72 ug/ml * Choleretic * CNS-Depressant * Enterotonic * Hypotensive * Pesticide *
13	JATRORRHIZINE	Stem	--	--	--	Suess, T. R. and Stermitz, F. R. 1981. The Constituents of Castilleja rhexifolia, Mahonia repens and Oncidium cebolleta. Dissertation Abstract Int B, 42: 1025-1026.
Antiinflammatory * Antimalarial IC50=0.42-1.61 ug/ml * Antiphotooxidative * Antiplasmodial IC50=0.42-1.61 ug/ml * CNS-Depressant * CNS-Stimulant * Enterotonic * Fungicide Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Hypotensive Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Pesticide * Protisticide IC50=0.42-1.61 ug/ml * Sedative Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Uterocontractant Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
13	JATRORRHIZINE	Root	--	--	--	*
Antiinflammatory * Antimalarial IC50=0.42-1.61 ug/ml * Antiphotooxidative * Antiplasmodial IC50=0.42-1.61 ug/ml * CNS-Depressant * CNS-Stimulant * Enterotonic * Fungicide Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Hypotensive Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Pesticide * Protisticide IC50=0.42-1.61 ug/ml * Sedative Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Uterocontractant Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
11	MAGNOFLORINE	Root	--	--	--	*
Antibacterial * Antineuromuscular ED50=10 mg/kg * Antispasmodic Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. CNS-Depressant Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. Curaroid <1% tubocurarine Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp. Hypotensive * PAF-Inhibitor * Paralytic Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp. Pesticide * Toxic Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp. Vasodilator Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
11	MAGNOFLORINE	Stem	--	--	--	Suess, T. R. and Stermitz, F. R. 1981. The Constituents of Castilleja rhexifolia, Mahonia repens and Oncidium cebolleta. Dissertation Abstract Int B, 42: 1025-1026.
Antibacterial * Antineuromuscular ED50=10 mg/kg * Antispasmodic Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. CNS-Depressant Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. Curaroid <1% tubocurarine Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp. Hypotensive * PAF-Inhibitor * Paralytic Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp. Pesticide * Toxic Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp. Vasodilator Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
4	OBABERINE	Stem	--	25.0	--	*
Antileishmanic * Antitrypanosomic * Pesticide * Protisticide *
4	OBABERINE	Root	--	--	--	Suess, T. R. and Stermitz, F. R. 1981. The Constituents of Castilleja rhexifolia, Mahonia repens and Oncidium cebolleta. Dissertation Abstract Int B, 42: 1025-1026.
Antileishmanic * Antitrypanosomic * Pesticide * Protisticide *
4	OBAMEGINE	Root	--	--	--	Suess, T. R. and Stermitz, F. R. 1981. The Constituents of Castilleja rhexifolia, Mahonia repens and Oncidium cebolleta. Dissertation Abstract Int B, 42: 1025-1026.
Antimalarial IC50=0.51 ug/ml (1/4 x chloroquine) * Hypotensive 1 mg/kg * Pesticide * Protisticide *
4	OBAMEGINE	Stem	--	35.0	--	*
Antimalarial IC50=0.51 ug/ml (1/4 x chloroquine) * Hypotensive 1 mg/kg * Pesticide * Protisticide *
10	OXYACANTHINE	Stem	--	--	--	*
Antibacterial * Anticarcinomic ED50=760 ppb * Antimalarial IC50=0.3 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. Antioxidant * Antiplasmodial IC50=0.3 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. Calcium-Antagonist IC50=0.98 uM pig * Choleretic * Cytotoxic >30 * Membranomodulator * Pesticide *
10	OXYACANTHINE	Root	--	--	--	Suess, T. R. and Stermitz, F. R. 1981. The Constituents of Castilleja rhexifolia, Mahonia repens and Oncidium cebolleta. Dissertation Abstract Int B, 42: 1025-1026.
Antibacterial * Anticarcinomic ED50=760 ppb * Antimalarial IC50=0.3 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. Antioxidant * Antiplasmodial IC50=0.3 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. Calcium-Antagonist IC50=0.98 uM pig * Choleretic * Cytotoxic >30 * Membranomodulator * Pesticide *
17	PALMATINE	Root	--	--	--	*
Abortifacient * Adrenocorticotrophic * Analgesic * Antialzheimeran? Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Antiarrhythmic * Antibacterial * Anticholinesterase Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Antiinfarctal * Antiinflammatory * Antimalarial * Antipyretic Grenand, P., Moretti, C., and Jacquemin, H. 1987. Pharmacopees Traditionnelles en Guyane. l'ORSTROM, Paris. 569 pp. CNS-Depressant * Hypotensive Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Inotropic * Pesticide * Respiradepressant * Uterotonic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.

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^*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.

Plant Mahonia repens (Berberidaceae)

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