Salvia gilliesii | Plant | Dr. Duke's Phytochemical and Ethnobotanical Databases

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Common name(s)

'Cordoba' Sage

How used

Medicinal

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Activities: 140

Chemicals w/Activities: 18

All Chemicals: 37

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# Activity	Chemical Name	Part	Low PPM	High PPM	StdDev	^*Reference
0	ALLO-AROMADENDRENE	Shoot	--	70.0	-0.10	Velasco-Negueruela, A. et al. 1993. The Essential Oil of Salvia gilliesii Benth. J. Ess. Oil Res. 5: 319-320.
0	ALPHA-COPAENE	Shoot	--	41.0	0.12	Velasco-Negueruela, A. et al. 1993. The Essential Oil of Salvia gilliesii Benth. J. Ess. Oil Res. 5: 319-320.
0	ALPHA-CUBEBENE	Shoot	--	5.0	-0.46	Velasco-Negueruela, A. et al. 1993. The Essential Oil of Salvia gilliesii Benth. J. Ess. Oil Res. 5: 319-320.
28	ALPHA-PINENE	Shoot	--	55.0	-0.14	Velasco-Negueruela, A. et al. 1993. The Essential Oil of Salvia gilliesii Benth. J. Ess. Oil Res. 5: 319-320.
Allelochemic * Allergenic * Antiacne * Antibacterial * Antifeedant * Antiflu Economic & Medicinal Plant Research, 5: 195. Antiinflammatory 500 mg/kg * Antipneumonic * Antiseptic * Antispasmodic * Antistaphylococcic * Antiviral Economic & Medicinal Plant Research, 5: 195. Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Coleoptophile * Expectorant Michael Castleman 1991. The Healing Herbs. Rodale Press, Emmaus, PA 436 pp. FLavor FEMA 15-150 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Herbicide IC50=30 uM Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp. Insecticide 0.82 uM/fly * Insectifuge 50 ppm * Insectiphile J. Stored. Prod. Res., 22:141, 1986. Irritant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. P450-2B1-Inhibitor IC50=0.087 uM * Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Pesticide * Sedative Lawrence Review of Natural Products, Jun-90. Spasmogenic * Tranquilizer Lawrence Review of Natural Products, Jun-90. Transdermal *
23	ALPHA-TERPINEOL	Shoot	--	7.5	-0.28	Velasco-Negueruela, A. et al. 1993. The Essential Oil of Salvia gilliesii Benth. J. Ess. Oil Res. 5: 319-320.
ACE-Inhibitor 100 ug/ml (weak activity) * Aldose-Reductase-Inhibitor 100 ug/ml Okamura, K., Iwakami, S., Matsunaga, T. 1992. Biological Activity of Monoterpenes from Trees. Toyama-Ken Yakuji Kenkyusho Nenpo, (20): 95-101. Allelopathic Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands. Antiacne * Antibacterial MIC=800-1,600 ug/ml Muroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105. Anticancer Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY. Anticariogenic MIC=800-1,600 ug/ml Muroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105. Antiinflammatory * Antiproliferant * Antiseptic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Cicatrizant ED50=240 ug/g mus * FLavor FEMA 5-40 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Insecticide 1.29 uM/fly * Interleukin-6-Inhibitor * Mosquitofuge > Deet * Motor-Depressant Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC Nematicide MLC=1 mg/ml Shoyakugaku Zasshi, 44: 183. Perfumery Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Pesticide * Sedative Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC Termiticide IC100=5 mg/g * Transdermal * Vulnerary ED50=240 ug/g mus *
0	ALPHA-THUJENE	Shoot	--	2.5	-0.51	Velasco-Negueruela, A. et al. 1993. The Essential Oil of Salvia gilliesii Benth. J. Ess. Oil Res. 5: 319-320.
6	ALPHA-THUJONE	Shoot	--	28.0	-0.27	Velasco-Negueruela, A. et al. 1993. The Essential Oil of Salvia gilliesii Benth. J. Ess. Oil Res. 5: 319-320.
Abortifacient Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp. Antibacterial J. Ess. Oil Res. 7: 271. Emmenagogue Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp. Insecticide * Larvicide Misra, L.N. and Singh, S.P. Alpha-Thujone, The Major Component Of The Essential Oil From Artemisia vulgaris Growing Wild In Nilgiri Hills. Journal of Natural Products, 49: 941, 1986. Pesticide *
3	AROMADENDRENE	Shoot	--	35.0	-0.17	Velasco-Negueruela, A. et al. 1993. The Essential Oil of Salvia gilliesii Benth. J. Ess. Oil Res. 5: 319-320.
Antiseptic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Pesticide *
0	BETA-BOURBONENE	Shoot	--	44.0	-0.05	Velasco-Negueruela, A. et al. 1993. The Essential Oil of Salvia gilliesii Benth. J. Ess. Oil Res. 5: 319-320.
0	BETA-CARYOPHYLLENE	Shoot	--	720.0	1.05	Velasco-Negueruela, A. et al. 1993. The Essential Oil of Salvia gilliesii Benth. J. Ess. Oil Res. 5: 319-320.
5	BETA-ELEMENE	Shoot	--	5.5	-0.32	Velasco-Negueruela, A. et al. 1993. The Essential Oil of Salvia gilliesii Benth. J. Ess. Oil Res. 5: 319-320.
Anticancer (Cervix) Medicinal and Poisonous Plants of the Tropics. Leeuwenberg, A.J.M., ed. Pudoc, Wageningen. 1987. Antigliomic * Antiproliferant * Antitumor (Cervix) Medicinal and Poisonous Plants of the Tropics. Leeuwenberg, A.J.M., ed. Pudoc, Wageningen. 1987. Apoptotic *
13	BETA-PINENE	Shoot	--	4.5	-0.12	Velasco-Negueruela, A. et al. 1993. The Essential Oil of Salvia gilliesii Benth. J. Ess. Oil Res. 5: 319-320.
Allergenic * Antiinflammatory * Antiseptic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. Antispasmodic * Candidicide * FLavor FEMA 15-600 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Herbicide Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp. Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253. Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Pesticide * Spasmogenic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp. Transdermal *
0	BICYCLOGERMACENE	Shoot	--	1420.0	--	Velasco-Negueruela, A. et al. 1993. The Essential Oil of Salvia gilliesii Benth. J. Ess. Oil Res. 5: 319-320.
9	CAMPHENE	Shoot	--	3.5	-0.13	Velasco-Negueruela, A. et al. 1993. The Essential Oil of Salvia gilliesii Benth. J. Ess. Oil Res. 5: 319-320.
Allelopathic Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands. Antilithic? Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antioxidant Jim Duke's personal files. Expectorant Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin. FLavor FEMA 15-175 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Hypocholesterolemic? Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Pesticide * Spasmogenic Fitoterapia No.59-1984.
41	CAMPHOR	Shoot	--	60.0	-0.16	Velasco-Negueruela, A. et al. 1993. The Essential Oil of Salvia gilliesii Benth. J. Ess. Oil Res. 5: 319-320.
Allelopathic * Analgesic * Anesthetic * Antiacne Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp. Antidiarrheic 500 ug/ml Wealth of India. Antidysenteric 500 ug/ml Wealth of India. Antiemetic 100-200 mg man orl Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. Antifeedant IC50=5,000 ppm diet Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp. Antifibrositic Martindale's 28th Antineuralgic Martindale's 28th Antipruritic Merck 11th Edition Antiseptic Merck 11th Edition Antispasmodic ED50=0.075 mg/ml Fitoterapia No.59-1984. Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Carminative Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994. CNS-Stimulant * Convulsant R.J. Hixtable (Huxtable, R.J. (as T. Max). 1992. This and That:The Essential Pharmacology of Herbs and Spices. Tips 13:15-20 Huxtable, R.J. 1992b. The Myth of Benficent Nature. The Risk of Herbal Preparations. Anns. Intern. Med. 117(2):165-6; Huxtable, R. Cosmetic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Counterirritant Martindale's 28th Decongestant Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp. Deliriant Merck 11th Edition Ecbolic * Emetic * Epileptigenic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp. Expectorant Martindale's 29th Fungicide ED50=2.7 mM Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp. Herbicide IC50=3.3-180 mM Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp. Insect-Repellent * Insectifuge * Irritant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Nematicide MLC=1 mg/ml Shoyakugaku Zasshi, 44: 183. Occuloirritant * P450-2B1-Inhibitor IC50=7.89 uM * Pesticide * Respirainhibitor Merck 11th Edition Respirastimulant Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. Rubefacient * Stimulant R.J. Hixtable (Huxtable, R.J. (as T. Max). 1992. This and That:The Essential Pharmacology of Herbs and Spices. Tips 13:15-20 Huxtable, R.J. 1992b. The Myth of Benficent Nature. The Risk of Herbal Preparations. Anns. Intern. Med. 117(2):165-6; Huxtable, R. Transdermal * Verrucolytic Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp. Vibriocide 500 ug/ml Wealth of India.
19	CARVONE	Shoot	--	34.0	-0.25	Velasco-Negueruela, A. et al. 1993. The Essential Oil of Salvia gilliesii Benth. J. Ess. Oil Res. 5: 319-320.
Allergenic * Antiacetylcholinesterase IC50=1.4-1.8 mM * Antiproliferative * Antiseptic 1.5 x phenol Wagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176) Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Candidistat * Carminative Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994. CNS-Stimulant * FLavor FEMA 80-3,000 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Fungistat * Insecticide Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Motor-Depressant Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC Nematicide MLC=1 mg/ml Shoyakugaku Zasshi, 44: 183. Perfumery Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Pesticide * Sedative Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC Trichomonicide LD100=300 ug/ml * Vermicide *
8	CARYOPHYLLENE-OXIDE	Shoot	--	205.0	0.05	Velasco-Negueruela, A. et al. 1993. The Essential Oil of Salvia gilliesii Benth. J. Ess. Oil Res. 5: 319-320.
Antiedemic Shimizu,M., et al. 1990. Anti-inflammatory Constituents of Topically Applied Crude Drugs. IV.1) Constituents and Anti-inflammatory Effect of Paraguayan Crude Drug 'Alhucema' (Lavandula latifolia Vill.)2). Chem. Pharm. Bull. 38(8): 2283-2284, 1990. Antifeedant Bettarini, F., Borgonovi, G.E., et al. 1991. Antiparasitic Compounds from East African Plants: Isolation and Biological Activity of Anonaine, Matricarianol, Canthin-6-One and Caryophyllene Oxide. Insect Sci. Applic. 14(1): 93-99, 1993. Antiinflammatory Shimizu,M., et al. 1990. Anti-inflammatory Constituents of Topically Applied Crude Drugs. IV.1) Constituents and Anti-inflammatory Effect of Paraguayan Crude Drug 'Alhucema' (Lavandula latifolia Vill.)2). Chem. Pharm. Bull. 38(8): 2283-2284, 1990. Antitumor Zheng, G-Q., Kenney, P.M., and Lam, L.K.T. Sesquiterpenes From Clove (Eugenia caryophyllata) As Potential Anticarcinogenic Agents. Journal of Natural Products 55(7): 999-1003, 1992. Calcium-Antagonist ED50=32 uM gpg * Fungicide * Insecticide Bettarini, F., Borgonovi, G.E., et al. 1991. Antiparasitic Compounds from East African Plants: Isolation and Biological Activity of Anonaine, Matricarianol, Canthin-6-One and Caryophyllene Oxide. Insect Sci. Applic. 14(1): 93-99, 1993. Pesticide *
0	CIS-CALAMENENE	Shoot	--	0.1	--	Velasco-Negueruela, A. et al. 1993. The Essential Oil of Salvia gilliesii Benth. J. Ess. Oil Res. 5: 319-320.
0	CIS-CARVEOL	Shoot	--	20.0	-0.38	Velasco-Negueruela, A. et al. 1993. The Essential Oil of Salvia gilliesii Benth. J. Ess. Oil Res. 5: 319-320.
0	CIS-VERBENOL	Shoot	--	2.5	-0.45	Velasco-Negueruela, A. et al. 1993. The Essential Oil of Salvia gilliesii Benth. J. Ess. Oil Res. 5: 319-320.

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^*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.

Plant Salvia gilliesii (Lamiaceae)

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