Pteridium aquilinum | Plant | Dr. Duke's Phytochemical and Ethnobotanical Databases

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Common name(s)

Bracken, Bracken Fern

How used

Medicinal

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Activities: 366

Chemicals w/Activities: 39

All Chemicals: 76

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# Activity	Chemical Name	Part Filter by plant part	Low PPM	High PPM	StdDev	^*Reference
0	2,4,6-TRIMETHYL-3-OXO-5-INDANACETIC-ACID	Plant	--	--	--	*
4	20-HYDROXYECDYSONE	Leaf	--	--	--	*
Antifeedant Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Antigonadotrophic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Juvabional 100-200 ppm; diet Russell, G. B., Phytochemical resources for crop protection, N. Z. J. Technol., 2, 1986, 127-134. Pesticide *
1	5-O-CAFFEOYLSHIKIMIC-ACID	Leaf	--	--	--	*
Leucocyte-Depressant Chemical Constituents of Oriental Herbs (3 diff. books)
0	ACETYLPTEROSINS	Leaf	--	--	--	*
0	ALPHA-ECDYSONE	Leaf	--	--	--	*
0	ANEURINASE	Plant	--	--	--	*
2	AQUILIDE-A	Plant	--	--	--	*
Carcinogenic Hutchings, A, Scott, AH, Lewis, G, and Cunningham, A. 1996. Zulu Medicinal Plants. An inventory. University of Natal Press, Pietermaritzburg. 450 pp. Mutagenic Hutchings, A, Scott, AH, Lewis, G, and Cunningham, A. 1996. Zulu Medicinal Plants. An inventory. University of Natal Press, Pietermaritzburg. 450 pp.
0	ARABINOSE	Plant	--	--	--	*
0	ASH	Rhizome	83000.0	92222.0	-0.27	*
0	ASH	Leaf	6000.0	68965.0	-0.88	*
20	BENZOIC-ACID	Plant	--	--	--	*
Allergenic Martindale's 28th Anesthetic * Antibacterial 33-1,250 ppm * Antibacterial MBC=800 ug/ml * Antiotitic Martindale's 28th Antipyretic * Antisalmonella MIC=800 ug/ml * Antiseptic 800 ug/ml * Antiyeast MFC=1,600 ug/ml * Choleretic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Expectorant * FLavor FEMA 250 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Fungicide MFC=1,600 ug/ml * Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Pesticide * Phytoalexin Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Tyrosinase-Inhibitor ID50=710 uM * Tyrosinase-Inhibitor ID50=640 uM * Uricosuric * Vulnerary *
0	BENZOYLPTEROSINS	Rhizome	--	--	--	*
53	BETA-CAROTENE	Leaf	--	1.0	-1.13	*
Allergenic * Androgenic? Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antiacne Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antiaging * Antiarthritic * Antiasthmatic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Anticancer Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY. Anticarcinomic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Anticervicaldysplasic * Anticoronary 50 mg/man/2 days * Antihyperkeratotic * Antiichythyotic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antileukoplakic * Antilipoperoxidant IC71=50 ug/ml * Antilupus 150 mg/man/day/2 mos Martindale's 28th Antimaculitic * Antimastitic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antimutagenic Economic & Medicinal Plant Research, 6: 235. Antioxidant Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antiozenic * Antipapillomic * Antiphotophobic 30-300 mg/man/day Martindale's 29th Antipityriasic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). AntiPMS * Antiporphyric 30-300 mg/man/day Martindale's 28th Antiproliferant Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY. Antipsoriac Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antiradicular Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antirheumatic * Antistress Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antitumor Simon, P.W. Carrots and Other Horticultural Crops as a Source of Provitamin A Carotenes. HortScience, 25(12): 1495, 1990. Antitumor (Breast) IC45=60 ug/ml * Antitumor (CNS) IC43=45 ug/ml * Antitumor (Colon) IC43=45 ug/ml * Antitumor (Lung) IC30=60 ug/ml * Antitumor (Prostate) * Antitumor (Stomach) IC26=45 ug/ml * Antiulcer 15,000-25,000 IU/day * Antiulcer 12 mg 3x/day/man/orl Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antixerophthalmic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Cancer-Preventive 22 ppm Jim Duke's personal files. Chemopreventive * Colorant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. COX-1-Inhibitor IC78=50 ug/ml * COX-2-Inhibitor IC82=50 ug/ml * Gastroprotective * Immunostimulant 180 mg/man/day/orl Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Interferon-Synergist * Mucogenic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Phagocytotic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Prooxidant 20 ug/g * Thymoprotective Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Ubiquiot Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
102	CAFFEIC-ACID	Plant	--	--	--	*
Aldose-Reductase-Inhibitor 4 ug/ml (weak activity) Ichikawa, K., et al. 1991. Isolation and Structure Determination of Aldose Reductase Inhibitors from Traditional Thai Medicine, and Syntheses of Their Derivatives. Sankyo Kenkyusho Nempo, 43: 99-110. Allergenic * Analgesic * Antiadenoviral Economic & Medicinal Plant Research, 5: 207. Antiaggregant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antiaging * Antiatherogenic * Antibacterial * Anticancer * Anticarcinogenic Economic & Medicinal Plant Research, 6: 189. Antidepressant * Antiedemic Economic & Medicinal Plant Research, 6: 189. Antielastase IC50=86 ug/ml (475 uM) * Antielastase IC50=93 um/l * Antiescherichic * Antiflu Economic & Medicinal Plant Research, 5: 207. Antigonadotropic Jim Duke's personal files. Antihemolytic 25 uM Ohnishi, M., Morishita, H., Iwahashi, H., Toda, S., Shirataki, Y., Kimura, M., and Kido, R. 1993. Inhibitory Effects of Chlorogenic Acids on Linoleic Acid Peroxidation and Haemolysis. Phytochemistry. 36(3): 579-583. 1994. Antihepatoadenomic 200 ppm diet orl mus * Antihepatotoxic * Antiherpetic EC50=>50 ug/ml * Antiherpetic 50 ug/ml * Antihistaminic * AntiHIV EC50=200 ug/ml * Antihypercholesterolemic Economic & Medicinal Plant Research, 6: 189. Antihyperthyroid * Antiinflammatory * AntiLegionella * Antileukemic Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46. Antileukotriene * Antimelanogenic * Antimutagenic Ki Soon Rhee. Oilseed Food Ingredients Used To Minimize Oxidative Flavor Deterioration in Meat Products. Phenolic Compounds in Food and Their Effects on Health, Ch.18. Antinitrosaminic Ki Soon Rhee. Oilseed Food Ingredients Used To Minimize Oxidative Flavor Deterioration in Meat Products. Phenolic Compounds in Food and Their Effects on Health, Ch.18. Antiophidic * Antioxidant 30 mM * Antioxidant 1/3 quercetin * Antioxidant 1.3 x Vit. E * Antioxidant IC57=30 ppm * Antioxidant 1/2 BHA * Antioxidant 50 uM * Antiperoxidant IC35=200 ug/ml * Antiperoxidant IC85=100 ug/ml * Antiperoxidant IC50=44 uM Planta Medica, 57: A54, 1991. Antiproliferant Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46. Antiprostaglandin * Antiradicular 30 mM * Antiradicular 1/3 quercetin * Antiradicular IC50=32-35 uM * Antiradicular 10 uM Ohnishi, M., Morishita, H., Iwahashi, H., Toda, S., Shirataki, Y., Kimura, M., and Kido, R. 1993. Inhibitory Effects of Chlorogenic Acids on Linoleic Acid Peroxidation and Haemolysis. Phytochemistry. 36(3): 579-583. 1994. Antiseptic * Antispasmodic EC50=3.4-15 uM Phytotherapy Research, 4: 73. Antistaphylococcic * Antistomatitic Economic & Medicinal Plant Research, 5: 207. Antisunburn * Antithiamin Phenolic Compounds in Food and Their Effects on Health, 69. Antithyroid Jim Duke's personal files. Antitumor 200 ppm diet orl mus * Antitumor (Skin) * Antitumor-Promoter IC42=10 uM Cancer Research, 48: 5941. Antiulcerogenic * Antivaccinia Economic & Medicinal Plant Research, 5: 207. Antiviral IC50=62.5 ug/ml * Anxiolytic * Calcium-Antagonist IC50=1.2 uM rbt * Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Carcinogenic 2% (diet) * Chemopreventive * Cholagogue Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp. Choleretic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Clastogenic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. CNS-Active Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp. Co-carcinogenic * Collagen-Sparing * COX-2-Inhibitor IC32=100 uM * Cytoprotective Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp. Cytotoxic TC50=200 ug/ml * Diuretic Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp. DNA-Active Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. DNA-Protective * Fungicide MIC=0.4 mg/ml * Hepatocarcinogenic 400 ppm diet orl mus (in the absence of alcohol) * Hepatoprotective Advance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 210. Hepatotropic * Histamine-Inhibitor * Immunostimulant * Insectifuge Tunon, H., Thorsell, W., and Bohlin, L. 1993. Mosquito Repelling Activity of Compounds Occurring in Achillea millefolium L. (Asteraceae). Economic Botany 48(2): 111-120, 1994. Leukotriene-Inhibitor * Lipoxygenase-Inhibitor IC50=62-148 uM * Lipoxygenase-Inhibitor IC27=5 mM Oszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690. Lyase-Inhibitor IC50=94-164 uM * Metal-Chelator McEvily, A.J., Iyengar, R., and Gross, A.T. Inhibition of Polyphenol Oxidase by Phenolic Compounds. Phenolic Compounds in Food and Their Effects on Health, Ch.25. Ornithine-Decarboxylase-Inhibitor Hagerman, A.E. Tannin-Protein Interactions. Phenolic Compounds in Food and Their Effects on Health, Ch.19. Pesticide * Prooxidant * Prostaglandigenic * Sedative 500 mg * Sunscreen IC50=2.5 mg/l Lazarova, G., Kostova, I., Neychev, H. 1992. Photodynamic damage prevention by some hydroxycoumarins. Fitoterapia 64(2): 134-136, 1993. Sunscreen IC91=5 mg/l Lazarova, G., Kostova, I., Neychev, H. 1992. Photodynamic damage prevention by some hydroxycoumarins. Fitoterapia 64(2): 134-136, 1993. Sunscreen IC98=25 mg/l Lazarova, G., Kostova, I., Neychev, H. 1992. Photodynamic damage prevention by some hydroxycoumarins. Fitoterapia 64(2): 134-136, 1993. Tumorigenic Jim Duke's personal files. Vulnerary Xanthine-Oxidase-Inhibitor IC50=39.21 uM Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
0	CAOUTCHOUC	Plant	--	--	--	*
0	CARBOHYDRATES	Leaf	56000.0	643678.0	0.25	*
0	CARBOHYDRATES	Rhizome	510000.0	566666.0	-1.19	*
0	CATECHOL-TANNIN	Rhizome	--	66000.0	--	*
10	CHICORIC-ACID	Plant	--	--	--	*
Antiflu Economic & Medicinal Plant Research, 5: 207. AntiHIV * AntiHIV-Integrase * Antiradicular * Antistomatitic Economic & Medicinal Plant Research, 5: 194. Antisunburn IC87=20 uM * Antiviral IC50=125 ug/ml Economic & Medicinal Plant Research, 5: 253. Immunostimulant 10-100 ug/ml * Pesticide * Phagocytotic 10-100 ug/ml *
14	CICHORIC-ACID	Plant	--	--	--	*
Antiflu Economic & Medicinal Plant Research, 5: 207. AntiHIV * AntiHIV-Integrase * Antiotitic * Antiradicular * Antistomatitic Economic & Medicinal Plant Research, 5: 194. Antisunburn IC87=20 uM * Antiviral IC50=125 ug/ml Economic & Medicinal Plant Research, 5: 253. Bacteristat * Collagen-Sparing IC87=20 uM * Hyaluronidase-Inhibitor * Immunostimulant 10-100 ug/ml * Pesticide * Phagocytotic 10-100 ug/ml *

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^*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.

Plant Pteridium aquilinum (Dennstaedtiaceae)

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