Pausinystalia johimbe | Plant | Dr. Duke's Phytochemical and Ethnobotanical Databases

Back to previous

Download a full report in PDF format

Common name(s)

Yohimbe

How used

Medicinal

Data Views

Activities: 83

Chemicals w/Activities: 8

All Chemicals: 13

CSV Excel PDF

Exclude ubiquitous chemicals - View the list of ubiquitous chemicals

List of all chemical
Click on column headings to sort table by that column
# Activity	Chemical Name	Part Filter by plant part	Low PPM	High PPM	StdDev	^*Reference
0	19-DEHYDROYOHIMBINE	Plant	--	--	--	*
16	AJMALINE	Bark	--	--	--	*
Adrenolytic Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin. Allergenic * Antiarrhythmic 200-300 mg/orl/man/day * Antihypertensive * Antihypertonic Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin. Calcium-Antagonist gpg * Cardiodepressant ANON. 1948-1976. The Wealth of India raw materials. Publications and Information Directorate, CSIR, New Delhi. 11 volumes. Cardiotoxic Martindale's 29th Convulsant Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp. Coronary-Dilator Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Hypotensive * Myocardiodepressant * Neurotoxic * Peristaltic ANON. 1948-1976. The Wealth of India raw materials. Publications and Information Directorate, CSIR, New Delhi. 11 volumes. Respirastimulant ANON. 1948-1976. The Wealth of India raw materials. Publications and Information Directorate, CSIR, New Delhi. 11 volumes. Tranquilizer Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
0	ALLOYOHIMBINE	Bark	--	--	--	*
2	ALPHA-YOHIMBINE	Plant	--	--	--	*
Antimalarial IC50=>200 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. Antiplasmodial IC50=>200 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
8	CORYNANTHEINE	Bark	--	--	--	*
Antimalarial IC50=81 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. Antiplasmodial IC50=81 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. Aphrodisiac * Bradycardic * Hypotensive * Sedative * Sympatholytic * Tranquilizer *
8	CORYNANTHINE	Bark	--	--	--	*
Adrenergic-Blocker * Anesthetic * Antimalarial IC50=>200 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. Antiplasmodial IC50=>200 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. Aphrodisiac * Bradycardic * Hypotensive * Sympatholytic *
7	DIHYDROCORYNANTHEINE	Bark	--	--	--	*
(-)-Chronotropic * Adrenergic-Blocker * Antiarrhythmic * Antihypertensive * Antimalarial IC50=66 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. Antiplasmodial IC50=66 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. Hypotensive *
0	DIHYDROSISSIRIKINE	Plant	--	--	--	*
0	PSEUDOYOHIMBINE	Bark	--	--	--	*
2	QUEBRACHINE	Bark	--	--	--	*
Hypotensive * Respirastimulant *
35	TANNIN	Bark	--	--	--	*
Anthelmintic * Antibacterial * Anticancer * Anticariogenic * Antidiarrheic * Antidysenteric * Antihepatotoxic * AntiHIV * Antihypertensive * Antilipolytic * Antimutagenic * Antinephritic Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990. Antiophidic Economic & Medicinal Plant Research, 5: 363. Antioxidant IC50=1.44 ug/ml * Antioxidant 1/3 quercetin * Antiradicular 500 mg/kg/day orl mus Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990. Antiradicular 1/3 quercetin * Antirenitic Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990. Antitumor * Antitumor-Promoter * Antiulcer * Antiviral * Cancer-Preventive HerbalGram No. 22 - Spring 1990, page 14. Carcinogenic * Chelator * Cyclooxygenase-Inhibitor * Glucosyl-Transferase-Inhibitor * Hepatoprotective * Immunosuppressant * Lipoxygenase-Inhibitor * MAO-Inhibitor * Ornithine-Decarboxylase-Inhibitor * Pesticide * Psychotropic Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990. Xanthine-Oxidase-Inhibitor *
0	TETRAHYDROMETHYLCORYNANTHEINE	Bark	--	--	--	*
37	YOHIMBINE	Bark	--	--	--	*
Adrenergic-Blocker * Adrenolytic 2 mg/kg ivn rbt Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006. Adrenolytic 5 mg/kg ivn rat Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006. Adrenolytic 0.2 mg/kg ivn dog Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006. Anesthetic * Antiacetylcholinesterase * Antianginal * Antiatherosclerotic * Antidepressant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antidiuretic Martindale's 28th Antidopaminergic * Antidote (Barbiturate) 0.25 mg/kg ivn dog Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006. Antihypertensive * Antiketaminic 0.25 mg/kg ivn cat Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006. Antiparaesthesic 6 mg/3xday/man/orl Martindale's 28th Antiserotonin Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Anxiogenic * Aphrodisiac Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Calcium-Antagonist 3 uM rat * Cardiotonic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. Cardiovascular 1 mg/kg ivn rat Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006. Cholinergic * CNS-Depressant Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. CNS-Depressant 8 mg/kg ivn rbt Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006. CNS-Depressant 5 mg/kg scu rat Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006. CNS-Stimulant * Emetic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. Hypertensive 5 mg/man orl * Hypothermic * MAO-Inhibitor * MDR-Inhibitor 10 uM Bhat, U. G., et al. 1995. A Structure-Function Relationship Among Reserpine and Yohimbine Analogues in Their Ability to Increase Expression of MDR1 and P-Glycoprotein in a Human Colon Carcinoma Cell Line. Mol Pharmacol, 48(4): 682-689. Mydriatic Merck 11th Edition Respirodepressant Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. Respirostimulant Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. Rhinorreic 20-30 mg/man * Sialogogue 0.3 mg/kg ivn rat * Tremorigenic *

^*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.

Plant Pausinystalia johimbe (Rubiaceae)

Data Views