Liquidambar orientalis | Plant | Dr. Duke's Phytochemical and Ethnobotanical Databases

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Common name(s)

Oriental Storax, Oriental Styrax

How used

Medicinal

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Activities: 161

Chemicals w/Activities: 13

All Chemicals: 27

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# Activity	Chemical Name	Part Filter by plant part	Low PPM	High PPM	StdDev	^*Reference
0	3-EPIOLEANOLIC-ACID	Resin, Exudate, Sap	--	--	--	*
0	ALPHA-SITOSTEROL	Resin, Exudate, Sap	--	--	--	*
0	ALPHA-STORESIN	Resin, Exudate, Sap	--	--	--	*
9	BENZYL-ALCOHOL	Resin, Exudate, Sap	--	--	--	*
Allergenic Martindale's 29th Anesthetic Martindale's 28th Antiodontalgic Martindale's 28th Antipruritic * Antiseptic Martindale's 29th FLavor Fema 200-1,200 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Fungicide * Pesticide * Sedative Jim Duke's personal files.
4	BENZYL-CINNAMATE	Resin, Exudate, Sap	--	--	--	*
Allergenic * FLavor FEMA 1-125 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253. Perfumery *
47	BETA-SITOSTEROL	Resin, Exudate, Sap	--	--	--	*
Androgenic * Angiogenic * Anorexic Martindale's 28th Antiadenomic Merck 11th Edition Antiandrogenic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Antibacterial Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155. Anticancer (Breast) Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103. Anticancer (Cervix) * Anticancer (Lung) * Antiedemic IC54=320 mg/kg orl * Antiestrogenic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Antifeedant Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Antifertility Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Antigonadotrophic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Antihyperlipoproteinaemic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antiinflammatory * Antileukemic * Antilymphomic * Antimutagenic 250 ug/ml * Antiophidic 2.3 mg mus Economic & Medicinal Plant Research, 5: 363. Antioxidant IC44=10 uM * Antiprogestational Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Antiprostaglandin 30 mg/day/12 wks * Antiprostatadenomic Merck 11th Edition Antiprostatitic 10-20 mg 3 x/day/orl man * Antipyretic Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp. Antitumor (Breast) Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103. Antitumor (Cervix) * Antitumor (Lung) * Antiviral Abid Ali Khan, M.M., Jain, D.C., Bhakuni, R.S., Zaim, M., and Thakur, R.S. 1991. Occurrence of some antiviral sterols in Artemisia annua. Plant Science, 75: 161-165, 1991. Apoptotic * Artemicide LC50=110 ppm Jung, J.H., Pummangura, S., Chaichantipyuth, c., Patarapanich, C., and McLaughlin, J.L. 1989. Bioactive Constituents of Melodorum fruticosum. Phytochemistry. 29(5): 1667-1670. 1990. Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Candidicide Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155. Caspase-8-Inducer * Estrogenic * Febrifuge Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp. Gonadotrophic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Hepatoprotective * Hypocholesterolemic 2-6 g/man/day/orl Martindale's 30th Hypocholesterolemic 9-3,330 mg/man/day/orl Martindale's 28th Hypoglycemic Ivorra, M.D., Paya, M., and Villar, A. 1989. A Review of Natural Products and Plants as Potential Antidiabetic Drugs. Journal of Ethnopharmacology, 27: 243-275, 1989. Hypolipidemic 2-6 g/day * Pesticide * Spermicide Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Ubiquiot Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Ulcerogenic 500 mg/kg ipr rat *
0	BETA-STORESIN	Resin, Exudate, Sap	--	--	--	*
18	CINNAMIC-ACID	Resin, Exudate, Sap	20000.0	150000.0	-1.00	*
Aldose-Reductase-Inhibitor 4 ug/ml (weak activity) Ichikawa, K., et al. 1991. Isolation and Structure Determination of Aldose Reductase Inhibitors from Traditional Thai Medicine, and Syntheses of Their Derivatives. Sankyo Kenkyusho Nempo, 43: 99-110. Allergenic * Anesthetic * Antibacterial Martindale's 28th Antiinflammatory * Antimutagenic Economic & Medicinal Plant Research, 6: 235. Antispasmodic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Choleretic * Dermatitigenic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. FLavor FEMA 4-40 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Fungicide * Herbicide * Laxative * Lipoxygenase-Inhibitor * Pesticide * Tyrosinase-Inhibitor ID50=700 uM * Vermifuge *
3	CINNAMIC-ALCOHOL	Resin, Exudate, Sap	--	--	--	*
Allergenic * FEMA 3-700 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
1	CINNAMYL-CINNAMATE	Resin, Exudate, Sap	50000.0	100000.0	1.00	*
FLavor FEMA <1 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
0	EO	Resin, Exudate, Sap	5000.0	10000.0	-1.60	*
24	ETHANOL	Resin, Exudate, Sap	--	--	--	*
Allergenic * Anesthetic 4,000 orl cat Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006. Anesthetic 6,000 orl rat Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006. Anhydrotic Martindale's 29th Antiatherosclerotic * Antibacterial Martindale's 28th Antipruritic Martindale's 28th Antiseptic Merck 11th Edition CNS-Depressant Martindale's 28th Expectorant Schulz, V, Hansel, R and Tyler, VE. 1998. Rational Phytotherapy - A Physician's Guide to Herbal Medicine. 3rd ed. 1st English Edition. Translated by Terry C. Telger. Springer Verlag, Heidelberg. 306 pp. Hepatotoxic Martindale's 29th Hypertensive >1 drink/day * Hypnotic Antidote=Naloxone Martindale's 29th Hypocalcemic 4,000 orl rat Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006. Hypotensive 1 drink/day * Mucotropic Schulz, V, Hansel, R and Tyler, VE. 1998. Rational Phytotherapy - A Physician's Guide to Herbal Medicine. 3rd ed. 1st English Edition. Translated by Terry C. Telger. Springer Verlag, Heidelberg. 306 pp. Neurolytic Merck 11th Edition Pesticide * Rubefacient Martindale's 29th Sclerosant Martindale's 29th Surfactant Schulz, V, Hansel, R and Tyler, VE. 1998. Rational Phytotherapy - A Physician's Guide to Herbal Medicine. 3rd ed. 1st English Edition. Translated by Terry C. Telger. Springer Verlag, Heidelberg. 306 pp. Teratogenic 6,000 orl dog Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006. Tremorilytic Martindale's 28th Ulcerogenic 5 ml/kg (50%) orl rat *
2	ETHYL-CINNAMATE	Resin, Exudate, Sap	--	--	--	*
FLavor FEMA 4-40 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Nematicide MLC=1,000 uM Shoyakugaku Zasshi, 44: 183.
0	MONOTROPEOSIDE	Plant	--	--	--	*
64	OLEANOLIC-ACID	Resin, Exudate, Sap	--	--	--	*
Abortifacient * Antiallergic * Antiarrhythmic 40 mg/kg * Antiatherosclerotic * Antibacterial MIC=625-1,250 ug/ml * Anticarcinomic Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46. Anticariogenic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. Anticomplement IC40-50 0.01 mM/l gpg Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin. Anticomplement IC80-90 0.05 mM/l gpg Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin. Antiedemic IC36=40 mg/kg ipr rat * Antifertility * Antigingivitic MIC=625-1,250 ug/ml * Antihepatotoxic * AntiHIV IC50=21.8 ug/ml * AntiHIV EC50=1.7 ug/ml Kashiwada, Y., et. al. 1998. Anti-AIDS Agents. 30. Anti-HIV Activity of Oleanolic Acid, Pomolic Acid, and Structurally Related Triterpenoids. J. Nat. Prod., 61 (9): 1090-1095. Antihyperlipidemic * Antiinflammatory 40 mg/kg ipr Aquino, R., De Feo, V., De Simone, F., Pizza, C., and Cirino, G. Plant Metabolites. New Compounds And Anti-Inflammatory Activity Of Uncaria tomentosa. Journal of Natural Products, 54(2): 453-459, 1991. Antiischemic 40 mg/kg Antileukemic Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46. Antileukotriene IC50=17 uM * Antimalarial IC50=70-89 ug/ml * Antinephritic IC50=19-24 uM * Antioxidant IC46=10 uM * Antioxidant Balanehru, S. and Nagarajan, B. 1992. Intervention of Adriamycin Induced Free Radical Damage. Biochemistry International 28(4): 735-744, 1992. Antiperiodontic MIC=625-1,250 ug/ml * Antiperoxidant IC30=200 ug/ml * AntiPGE2 IC50=24 uM * Antiplaque MIC=625-1,250 ug/ml * Antiplasmodial IC50=70-89 ug/ml * Antisarcomic * Antiseptic MIC=625-1,250 ug/ml * AntiTGF-beta IC50=19-24 uM * Antitumor * Antitumor (Breast) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46. Antitumor (Colon) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46. Antitumor (Kidney) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46. Antitumor (Lung) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46. Antitumor (Pancreas) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46. Antiulcer >carbenoxolone * Antiviral EC50=1.7 ug/ml Kashiwada, Y., et. al. 1998. Anti-AIDS Agents. 30. Anti-HIV Activity of Oleanolic Acid, Pomolic Acid, and Structurally Related Triterpenoids. J. Nat. Prod., 61 (9): 1090-1095. Antiviral IC50=21.8 ug/ml Kashiwada, Y., et. al. 1998. Anti-AIDS Agents. 30. Anti-HIV Activity of Oleanolic Acid, Pomolic Acid, and Structurally Related Triterpenoids. J. Nat. Prod., 61 (9): 1090-1095. Aromatase-Inhibitor * Beta-Blocker * Beta-Glucuronidase-Inhibitor ~100 mg/kg * Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Cardioprotective 40 mg/kg * Cardiotonic * COX-2-Inhibitor Ringbom, T., Seguar, L., Noreen, Y., Perera, P., Bohlin, L. 1998. Ursolic Acid from Plantago major, a Selective Inhibitor of Cyclooxygenase-2 Catalyzed Prostaglandin Biosynthesis. J. Nat. Prod., 61(10): 1212-1215. COX-2-Inhibitor IC50=295 uM/ * Cyclooxygenase-Inhibitor * Diuretic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. Elastase-Inhibitor IC50=~15 uM * Hepatoprotective Advance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 211. Hypolipemic * Hypotensive * Immunomodulator * Leucocytogenic * NF-kB-Inhibitor * Phagocytotic * Piscicide ANON. 1948-1976. The Wealth of India raw materials. Publications and Information Directorate, CSIR, New Delhi. 11 volumes. Prostaglandin-Synthesis-Inhibitor igs mus * Sedative * Uterotonic * Vasopressor *
0	PHENYLETHYLENE	Resin, Exudate, Sap	--	--	--	*
0	PHENYLPROPYL-ALCOHOL	Resin, Exudate, Sap	--	--	--	*
0	PHENYLPROPYL-CINNAMATE	Resin, Exudate, Sap	--	100000.0	--	*
14	SHIKIMIC-ACID	Plant	--	--	--	*
Analgesic * Anticancer * Anticonvulsant Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp. Antioxidant 7 x quercetin * Antiradicular 7 x quercetin * Antispasmodic Grenand, P., Moretti, C., and Jacquemin, H. 1987. Pharmacopees Traditionnelles en Guyane. l'ORSTROM, Paris. 569 pp. Antitumor * Antitumor-Promoter * Bruchifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Cancer-Preventive * Carcinogenic Merck 11th Edition Ileorelaxant * Mutagenic * Pesticide *
0	STORESIN	Resin, Exudate, Sap	330000.0	500000.0	--	*

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^*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.

Plant Liquidambar orientalis (Hamamelidaceae)

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