Levisticum officinale | Plant | Dr. Duke's Phytochemical and Ethnobotanical Databases

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Common name(s)

Lovage

How used

Food

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Activities: 447

Chemicals w/Activities: 65

All Chemicals: 124

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List of all chemical
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# Activity	Chemical Name	Part Filter by plant part	Low PPM	High PPM	StdDev	^*Reference
0	(+)-FALCARINDIOL	Root	--	600.0	--	*
67	1,8-CINEOLE	Root	--	--	--	Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
(-)-Chronotropic 87 nl/ml Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin. (-)-Inotropic 87 nl/ml Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin. Acaricide LC100=6 uM * Allelopathic * Allergenic * Anesthetic * Anthelmintic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antiacetylcholinesterase IC50=41 ug/ml * Antiallergic J. Food Hyg. Soc. Jap. 33(6): 569. Antibacterial 50 ppm * Antibronchitic * Anticariogenic * Anticatarrh Martindale's 29th Anticholinesterase IC50=50-70 * Antifatigue * Antihalitosic American Health, 12(4): 17, 1993. Antiinflammatory * Antilaryngitic * Antinociceptive * Antipharyngitic * Antiplaque * Antirheumatic * Antirhinitic * Antiseptic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antisinusitic * Antispasmodic * Antistaphylococcic 50 ppm * Antitussive * Antiulcer * Candidicide * Carcinogenic Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253. Choleretic * CNS-Stimulant * Convulsant * Counterirritant Martindale's 29th Cytochrome-P450-Inducer * Decongestant * Degranulant 0.3 ul/ml * Dentifrice Martindale's 29th Edemagenic inj * Expectorant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. FLavor FEMA 1-200 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Fungicide * Gastroprotective * Gram(+)icide * Gram(-)icide * Hepatotonic * Herbicide IC50=78 uM Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp. Hypotensive * Inflammatory inj * Insectifuge * Irritant Rinzler, C. A. 1990. The Complete Book of Herbs, Spices and Condiments. Facts on File, New York. 199 pp. Myorelaxant Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp. Nematicide Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp. Neurotoxic * P450-Inducer * Pediculicide 2.3 x pyrethrin * Perfume Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Pesticide * Rubefacient Martindale's 29th Secretogogue * Sedative * Spasmogenic * Surfactant * Testosterone-Hydroxylase-Inducer * Transdermal * Trichomonicide LD100=1,000 ug/ml *
0	2-METHYL-BUTANAL	Root	--	--	--	Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
0	2-OCTANONE	Root	--	--	--	Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
0	3-BUTYL-4,5-DIHYDROPHTHALIDE	Root	--	--	--	*
0	3-BUTYLPHTHALIDE	Root	600.0	5440.0	--	Bisset, N.G., ed. 1994. Herbal Drugs and Phytopharmaceuticals. CRC Press. Boca Raton, FL. 566 pp.
0	4-OCTANONE	Root	--	--	--	Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
10	5-METHOXY-PSORALEN	Fruit	--	6.0	-0.56	Abstract (See species file)
Antimutagenic Economic & Medicinal Plant Research, 6: 235. Antipsoriac Martindale's 29th Antitumor Economic & Medicinal Plant Research, 6: 189. Antivitiligic Economic & Medicinal Plant Research, 6: 189. Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Carcinogenic? Martindale's 29th Fungicide * Melaninogenic Economic & Medicinal Plant Research, 6: 189. Melatoninogenic Medline (post 1990 searches filed in my computer) Photodermatitigenic *
21	8-METHOXY-PSORALEN	Fruit	0.0	1.0	-0.71	Abstract (See species file)
Antialopecic Martindale's 28th Antibacterial 6-100 ppm * Antilymphomic 0.6 mg/kg orl * Antimycotic 20-50 mg/man/day Martindale's 28th Antipsoriac 20-50 mg/man/day Martindale's 28th Antistaphylococcic 100 ppm * Antitumor Economic & Medicinal Plant Research, 6: 189. Antiviral * Antivitiligic Economic & Medicinal Plant Research, 6: 189. Candidicide 100 ppm * Carcinogenic * Fungicide 100 ppm * Fungicide IC50=300 uM * Immunosuppressant Economic & Medicinal Plant Research, 6: 189. Lymphocytogenic Gawron, A., Gorski, G., Glowniak, K. 1989. Increased proliferation of phytohaemagglutinin (PHA)-stimulated human leucocytes after 8-methoxypsoralen treatment. J. Pharm. Pharmacol. 42: 194-195, 1990. Melaninogenic Economic & Medicinal Plant Research, 6: 189. Mitogenic 1 ug/mL Gawron, A., Gorski, G., Glowniak*, K. 1989. Increased proliferation of phytohaemagglutinin (PHA)-stimulated human leucocytes after 8-methoxypsoralen treatment. J. Pharm. Pharmacol. 42: 194-195, 1990. Mutagenic Pesticide * Photodermatitigenic * Phototoxic *
16	ACETIC-ACID	Root	--	--	--	Guenther, E., The Essential Oils, 6 volumes, D. van Nostrand, New York, 1948-1952.
Acidulant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antibacterial 5,000 ppm * Antiotitic Martindale's 28th Antisalmonella * Antivaginitic 1-2% * Expectorant Martindale's 28th Fungicide Martindale's 29th Keratitigenic * Mucolytic Martindale's 29th Osteolytic * Perfumery FEMA 6,000-40,000 ppm Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Pesticide * Protisticide Martindale's 29th Spermicide Martindale's 28th Ulcerogenic HerbalGram No. 20, page 9. Verrucolytic *
0	ALKYL-PHTHALIDES	Root	1400.0	11900.0	--	*
0	ALPHA-FENCHYL-ALCOHOL	Root	--	--	--	Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
0	ALPHA-P-DIMETHYL-STYRENE	Root	3.0	30.0	--	Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
11	ALPHA-PHELLANDRENE	Root	1.0	10.0	--	*
Antibacterial Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands. Antistaphylococcic Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands. Dermal Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Emetic * FLavor FEMA 10-130 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Fungicide Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin. Insectiphile Pakistan Encyclopedia Planta Medica. 1986. Irritant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Laxative * Perfumery Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Pesticide *
28	ALPHA-PINENE	Root	20.0	200.0	-0.69	*
Allelochemic * Allergenic * Antiacne * Antibacterial * Antifeedant * Antiflu Economic & Medicinal Plant Research, 5: 195. Antiinflammatory 500 mg/kg * Antipneumonic * Antiseptic * Antispasmodic * Antistaphylococcic * Antiviral Economic & Medicinal Plant Research, 5: 195. Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Coleoptophile * Expectorant Michael Castleman 1991. The Healing Herbs. Rodale Press, Emmaus, PA 436 pp. FLavor FEMA 15-150 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Herbicide IC50=30 uM Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp. Insecticide 0.82 uM/fly * Insectifuge 50 ppm * Insectiphile J. Stored. Prod. Res., 22:141, 1986. Irritant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. P450-2B1-Inhibitor IC50=0.087 uM * Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Pesticide * Sedative Lawrence Review of Natural Products, Jun-90. Spasmogenic * Tranquilizer Lawrence Review of Natural Products, Jun-90. Transdermal *
3	ALPHA-SELINENE	Root	10.0	100.0	--	Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Antimalarial IC50=>50 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. Antiplasmodial IC50=>50 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
13	ALPHA-TERPINENE	Root	1.0	10.0	-0.62	Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Acaricide * ACE-Inhibitor 100 ug/ml (weak activity) * Aldose-Reductase-Inhibitor 100 ug/ml Okamura, K., Iwakami, S., Matsunaga, T. 1992. Biological Activity of Monoterpenes from Trees. Toyama-Ken Yakuji Kenkyusho Nenpo, (20): 95-101. Antiacetylcholinesterase IC50=1.0 mM * Antinitrosaminic * Antispasmodic * FLavor FEMA 1-40 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Insecticide 0.86 uM/fly * Insectifuge * P450-2B1-Inhibitor IC50=0.76 uM * Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Pesticide * Spasmogenic *
23	ALPHA-TERPINEOL	Root	8.0	80.0	-0.49	Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
ACE-Inhibitor 100 ug/ml (weak activity) * Aldose-Reductase-Inhibitor 100 ug/ml Okamura, K., Iwakami, S., Matsunaga, T. 1992. Biological Activity of Monoterpenes from Trees. Toyama-Ken Yakuji Kenkyusho Nenpo, (20): 95-101. Allelopathic Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands. Antiacne * Antibacterial MIC=800-1,600 ug/ml Muroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105. Anticancer Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY. Anticariogenic MIC=800-1,600 ug/ml Muroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105. Antiinflammatory * Antiproliferant * Antiseptic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Cicatrizant ED50=240 ug/g mus * FLavor FEMA 5-40 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Insecticide 1.29 uM/fly * Interleukin-6-Inhibitor * Mosquitofuge > Deet * Motor-Depressant Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC Nematicide MLC=1 mg/ml Shoyakugaku Zasshi, 44: 183. Perfumery Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Pesticide * Sedative Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC Termiticide IC100=5 mg/g * Transdermal * Vulnerary ED50=240 ug/g mus *
0	ALPHA-TERPINYL-ACETATE	Leaf	--	--	--	Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
1	ANGELIC-ACID	Root	--	--	--	List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Sedative *

List of all activity chemical
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# Activity	Chemical Name	Part Filter by plant part	Low PPM	High PPM	StdDev	^*Reference

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^*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.

Plant Levisticum officinale (Apiaceae)

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