Eupatorium perfoliatum | Plant | Dr. Duke's Phytochemical and Ethnobotanical Databases

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Common name(s)

Boneset

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Medicinal

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Activities: 483

Chemicals w/Activities: 31

All Chemicals: 49

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# Activity	Chemical Name	Part	Low PPM	High PPM	StdDev	^*Reference
0	11,13ALPHA-DIHYDROEUPERFOLIDE	Plant	--	--	--	*
3	4-O-METHYL-GLUCURONOXYLAN	Plant	--	--	--	*
Immunostimulant Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Phagocytotic * Phagocytotic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
0	7-HYDROXY-7-HYDRO-6-DEHYDRO-3,4(Z)-ALPHA-FARNESENE	Plant	--	--	--	*
0	8BETA-ANGELOYLOXYEUPATUNDIN	Plant	--	--	--	*
112	ASCORBIC-ACID	Plant	--	--	--	*
Acidulant FEMA 6,000 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Aldose-Reductase-Inhibitor Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Analgesic 5-10 g/day * Angiotensin-Receptor-Blocker * AntiAGE 2,000 mg/day Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Antiaggregant Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Antiaging 400 mg/day * Antiallergic * Antialzheimeran 2,000-6,000 mg/day * Antiarthritic 0.2-1 g/day * Antiasthmatic 1,000 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antiatherosclerotic * Antibacterial Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Anticataract 400 mg/day Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Anticataract 350 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Anticataract 1 g 3x/day * Anticervicaldysplasic 1,000-2,000 mg/day * AntiCFS 500-1,000 mg * Anticlimacteric 500-5,000 mg/day * Anticold 1-2 g/man/day * AntiCrohn's 50-100 mg/day/orl/man Martindale's 29th AntiCTS 1,000 mg 3x/day * Antidecubitic 500 mg/man/2x/day Martindale's 28th Antidementia * Antidepressant 2,000 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antidiabetic Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Antidote (Aluminum) Economic & Medicinal Plant Research, 6: 189. Antidote (Cadmium) Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antidote (Lead) Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antidote (Paraquat) Martindale's 28th Antieczemic 3.5-5 g/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antiedemic 1 g/man/day Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antiencephalitic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antiendometriotic 2,000 mg/day * Antifatigue 500-1,000 mg * Antifibrotic 1,000-2,000 mg * Antigallstone 1,000-3,000 mg/day * Antigastritic * Antigingivitic * Antiglaucomic 2 g/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antihangover 1,000 mg * Antihemorrhagic 1 g/man/day Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antihepatitic 2-6 g/man/day Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antihepatotoxic Economic & Medicinal Plant Research, 6: 189. Antiherpetic 1-5 g/day * Antihistaminic 2 g/day orl man * Antihypertensive * Antiinfertility 1 g/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antiinflammatory Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antilepric 1.5 g/man/day Martindale's 28th Antilithic 1,000-3,000 mg/day * AntiLyme 500-2,000 mg * Antimaculitic * Antimeasles Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antimenopausal 500-5,000 mg/day * Antimigraine Martindale's 29th Antimutagenic Economic & Medicinal Plant Research, 6: 235. Antineuramidase * Antinitrosic 1 g/man/day Martindale's 28th Antiobesity 1 g 3x/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antiorchitic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antiosteoarthritic 1 g 2x/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antiosteoporotic 500 mg/day * Antioxidant 100 ppm * Antiparkinsonian 1 g 2-3x/day * Antiparotitic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antiperiodontitic 1 g 2x/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antipneumonic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antipodriac Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antipoliomyelitic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antipyretic Economic & Medicinal Plant Research, 6: 189. Antiradicular Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 AntiRaynaud's 500 mg 1-2x/day * Antiretinotic * Antirheumatic * Antirhinitic 1,000 mg 3x/day * Antiscorbutic 10 mg/man/day Martindale's 28th Antiseptic 4-8 g/day Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Antiseptic MIC=3.3-217 mg/ml Martindale's 28th Antishingles Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antispasmodic 500-5,000 mg/day * Antistress 500-1,000 mg * Antisyndrome-X 1-4 g/day Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Antitumor (Gastric) * Antitumor (Lung) * Antiulcer * Antiviral 1-5 g/day * Apoptotic 1-10 mM * Asthma-preventive 1,000 mg/day/orl Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Beta-Adrenergic Receptor Blocker * Beta-Glucuronidase-Inhibitor 1.5 g/day/man * Calcium-Antagonist * Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Cardioprotective * Cold-preventive 1-2 g/day Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Collagenic * Detoxicant * Diuretic 700 mg/man/orl * Fistula-Preventive Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Hypocholesterolemic 300-1,000 mg/day Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Hypoglycemic Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Hypotensive 1,000 mg/man/day * Immunomodulator * Immunostimulant Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Interferonogenic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Lithogenic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Mucolytic 1 g/woman/day Martindale's 28th Pesticide * Uricosuric 4 g/man/day Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Urinary-Acidulant Martindale's 29th Vasodilator * Vulnerary Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
0	ASH	Plant	6030.0	67000.0	-0.98	*
7	ASTRAGALIN	Plant	--	--	--	*
ACE-Inhibitor ID50=180 ug/ml rat (24 hr.) * Aldose-Reductase-Inhibitor IC30=1 uM * Aldose-Reductase-Inhibitor IC62=10 uM Shimizu, M., Ito, T., Terashima, S., Hayashi, T., Arisawa, M., Morita, N., Kurokawa, S., Ito, K., and Hashimoto, Y. 1984. Inhibition of Lens Aldose Reductase by Flavonoids. Phytochemistry, 23: 1885-1888. Antileukemic * Expectorant * Hypotensive Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990. Immunostimulant *
53	BETA-CAROTENE	Plant	--	--	--	*
Allergenic * Androgenic? Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antiacne Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antiaging * Antiarthritic * Antiasthmatic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Anticancer Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY. Anticarcinomic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Anticervicaldysplasic * Anticoronary 50 mg/man/2 days * Antihyperkeratotic * Antiichythyotic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antileukoplakic * Antilipoperoxidant IC71=50 ug/ml * Antilupus 150 mg/man/day/2 mos Martindale's 28th Antimaculitic * Antimastitic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antimutagenic Economic & Medicinal Plant Research, 6: 235. Antioxidant Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antiozenic * Antipapillomic * Antiphotophobic 30-300 mg/man/day Martindale's 29th Antipityriasic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). AntiPMS * Antiporphyric 30-300 mg/man/day Martindale's 28th Antiproliferant Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY. Antipsoriac Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antiradicular Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antirheumatic * Antistress Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antitumor Simon, P.W. Carrots and Other Horticultural Crops as a Source of Provitamin A Carotenes. HortScience, 25(12): 1495, 1990. Antitumor (Breast) IC45=60 ug/ml * Antitumor (CNS) IC43=45 ug/ml * Antitumor (Colon) IC43=45 ug/ml * Antitumor (Lung) IC30=60 ug/ml * Antitumor (Prostate) * Antitumor (Stomach) IC26=45 ug/ml * Antiulcer 12 mg 3x/day/man/orl Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antiulcer 15,000-25,000 IU/day * Antixerophthalmic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Cancer-Preventive 22 ppm Jim Duke's personal files. Chemopreventive * Colorant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. COX-1-Inhibitor IC78=50 ug/ml * COX-2-Inhibitor IC82=50 ug/ml * Gastroprotective * Immunostimulant 180 mg/man/day/orl Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Interferon-Synergist * Mucogenic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Phagocytotic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Prooxidant 20 ug/g * Thymoprotective Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Ubiquiot Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
28	CALCIUM	Plant	1260.0	14000.0	0.04	*
Antiallergic 500 mg/day * Antianxiety Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antiarrhythmic 500-1,500 mg * Antiarthritic 1,000 mg/day * Antiatherosclerotic 500 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Anticlimacteric 1,000-1,500 mg/day * Antidepressant Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antidote (Aluminum) Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antidote (Lead) Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antihyperkinetic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antihypertensive * Antiinsomniac Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antimenopausal 1,000-1,500 mg/day * Antiobesity * Antiosteoporotic 500-2,000 mg/day * Antiperiodontitic 750 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. AntiPMS 1 g/day * Antirheumatic 1,000 mg/day * Antistress 500-1,500 mg/day * Antitic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Anxiolytic 500-1,500 mg/day * Calcium-Channel-Blocker * Diuretic * Hypocholesterolemic 500 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Hypotensive 1 g/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Laxative 1,000-1,200 mg * Tranquilizer 500-1,500 mg/day * Vasodilator *
24	CHROMIUM	Plant	--	--	--	*
Amphiglycemic? Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antiacne * AntiAGE 200-1,000 ug Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Antiaging 200-1,000 ug Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Antiatherosclerotic 20 ug/day * AntiCFS 200 ug * Anticorneotic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antidiabetic 200-1,000 ug * Antidote (Lead) Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antifatigue 200 ug * Antiglycosuric 200-1,000 ug * Antiobesity 200-1,000 ug Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Antisyndrome-X 200-800 ug Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Antitriglyceride 200-1,000 ug Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Antitriglyceride 20 ug/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Cardioprotective * Energizer * Hypocholesterolemic 200-1,000 ug Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Hypocholesterolemic 20 ug/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Hypoglycemic 200-1,000 ug Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Hypotensive 200-1,000 ug Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Immunomodulator * Insulinogenic * Memorigenic *
2	COBALT	Plant	--	--	--	*
Cardiomyopathogenic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Erythrocytogenic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
0	DENDROIDINIC-ACID	Plant	--	--	--	*
0	EUCANNABINOLIDE	Plant	--	--	--	*
1	EUFOLIATIN	Plant	--	--	--	*
Immunostimulant ED27=1 uM *
1	EUFOLIATORIN	Plant	--	--	--	*
Immunostimulant ED10=1 uM *
0	EUPAFOLIN	Plant	--	--	--	*
8	EUPATORIN	Plant	--	--	--	*
Antibacterial List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979. Anticarcinomic ED50=4.6 Biosyn. Prod. Cancer Chemotherapy (Petit et al) Antimalarial IC50=65 uM * Cytotoxic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Emetic * Immunostimulant * Parasiticide IC50=65 uM * Plasmodicide IC50=65 uM *
0	EUPERFOLIDE	Plant	--	--	--	*
1	EUPERFOLIN	Plant	--	--	--	*
Immunostimulant ED42=1 uM *
1	EUPERFOLITIN	Plant	--	--	--	*
Immunostimulant ED12=1 uM *

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^*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.

Plant Eupatorium perfoliatum (Asteraceae)

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