Erythroxylum novogranatense | Plant | Dr. Duke's Phytochemical and Ethnobotanical Databases

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Common name(s)

Coca

How used

Medicinal

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Activities: 250

Chemicals w/Activities: 13

All Chemicals: 25

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# Activity	Chemical Name	Part Filter by plant part	Low PPM	High PPM	StdDev	^*Reference
0	(+)-CATECHIN-3-O-ALPHA-L-RHAMNOPYRANOSIDE	Stem	--	--	--	*
0	(+)-CATECHIN-3-RHAMNOSIDE	Plant	--	--	--	*
0	ALKALOIDS	Leaf	--	14000.0	0.33	*
0	BENZOYLECGONINE	Leaf	--	--	--	*
28	CALCIUM	Leaf	10200.0	13000.0	-0.37	*
Antiallergic 500 mg/day * Antianxiety Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antiarrhythmic 500-1,500 mg * Antiarthritic 1,000 mg/day * Antiatherosclerotic 500 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Anticlimacteric 1,000-1,500 mg/day * Antidepressant Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antidote (Aluminum) Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antidote (Lead) Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antihyperkinetic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antihypertensive * Antiinsomniac Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antimenopausal 1,000-1,500 mg/day * Antiobesity * Antiosteoporotic 500-2,000 mg/day * Antiperiodontitic 750 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. AntiPMS 1 g/day * Antirheumatic 1,000 mg/day * Antistress 500-1,500 mg/day * Antitic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Anxiolytic 500-1,500 mg/day * Calcium-Channel-Blocker * Diuretic * Hypocholesterolemic 500 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Hypotensive 1 g/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Laxative 1,000-1,200 mg * Tranquilizer 500-1,500 mg/day * Vasodilator *
0	CINNAMYLCOCAINE	Leaf	--	--	--	*
27	COCAINE	Leaf	--	--	--	*
Anesthetic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Anorexic Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. Antiarrhythmic Cardiology from Nature.(by Authur Hollman, s.d.) Telectronics Pacing System, London. 13 pp. Antibacterial * Antiepistactic Martindale's 29th Antifeedant * Arterioconstrictor * Cardiotonic * CNS-Stimulant 0.06 mg/kg ivn rat * CNS-Stimulant 20 mg/kg scu mus Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006. Convulsant 10.5 mg/kg ivn rat Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006. Debridemant Martindale's 29th Dermatitigenic Mitchell, J. and Rook, A.J. 1923. Botanical Dermatology: plants and plant products injurious to the skin. Vancouver: Greengrass, 1979. xiii, 787 p.: ill. Diuretic 10 mg/kg scu dog Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006. Hallucinogen Martindale's 29th Hepatotoxic * Hypertensive * Hypotensive * Mydriatic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Narcotic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Neurotoxic R.J. Hixtable (Huxtable, R.J. (as T. Max). 1992. This and That:The Essential Pharmacology of Herbs and Spices. Tips 13:15-20 Huxtable, R.J. 1992b. The Myth of Benficent Nature. The Risk of Herbal Preparations. Anns. Intern. Med. 117(2):165-6; Huxtable, R. Occuloirritant Mitchell, J. and Rook, A.J. 1923. Botanical Dermatology: plants and plant products injurious to the skin. Vancouver: Greengrass, 1979. xiii, 787 p.: ill. Pesticide * Psychotomimetic Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. Pyrogenic 5 mg/kg ivn mky Wilson, M. C., Bedford, J. A., Buelke, J., Kibbe, A. H. 1976. Acute Pharmacological Activity of Intravenous Cocaine in the Rhesus Monkey. Psychopharmacol Commun, 2: 251. Tremorigenic Martindale's 28th Vasoconstrictor Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
12	COPPER	Leaf	2.5	2.7	-0.69	*
Antianemic * Antiarthritic * Antidiabetic 2-4 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antifatigue * Antiinflammatory Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antinociceptive Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antiosteoporotic * Cardioprotective * Contraceptive Martindale's 28th Hypocholesterolemic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Immunomodulator * Schizophrenigenic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
0	ERYTHRODIOL	Fruit	--	--	--	*
8	GENTISIC-ACID	Leaf	--	--	--	*
Analgesic Merck 11th Edition Antibacterial Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antifeedant * Antiinflammatory Merck 11th Edition Antioxidant 1/3 BHA * Antirheumatic Grenand, P., Moretti, C., and Jacquemin, H. 1987. Pharmacopees Traditionnelles en Guyane. l'ORSTROM, Paris. 569 pp. Antiviral Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Pesticide *
6	IRON	Leaf	86.0	97.0	-0.67	*
Antiakathisic Martindale's 29th Antianemic Martindale's 29th Anticanker * Anticheilitic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antimenorrhagic 100 mg/day/wmn/orl Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Prooxidant *
22	ISOQUERCITRIN	Leaf	--	100.0	-0.32	*
ACE-Inhibitor ID50=300 ug/ml rat (24 hr.) * Aldose-Reductase-Inhibitor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antibacterial Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Anticancer * Antielastase IC50=0.7 ug/ml * Antifeedant Russell, G. B., Phytochemical resources for crop protection, N. Z. J. Technol., 2, 1986, 127-134. Antiinflammatory * Antinociceptive * Antioxidant 1/4 quercetin * Antioxidant IC50=9.0 uM * Antiradicular 1/4 quercetin * Antitumor * Antitumor-Promoter * Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Capillarigenic * Diaphoretic * Diuretic 10 ppm List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979. Hypotensive Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990. Insectiphile Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Pesticide * TNF-alpha-Inhibitor * Topoisomerase-II-Inhibitor 550 ug/ml Bernard, F. X., Sable, S., Cameron, B., Provost, J., Desnottes, J. F., Crouzet, J., Blanche, F. 1997. Glycosylated Flavones as Selective Inhibitors of Topoisomerase IV. Antimicrobial Agents & Chemotherapy, 41: 992-998.
4	KAEMPFEROL-3-O-GLUCOSIDE	Leaf	--	--	--	*
AntiHIV * Antiviral * Choleretic Fitoterapia No.5-1986. Pesticide *
0	KAEMPFEROL-3-O-RUTINOSIDE	Leaf	--	--	--	*
65	MAGNESIUM	Leaf	3800.0	6900.0	1.07	*
Antiaggregant 400 mg/day * Antialcoholic * Antianginal 400 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antianorectic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antianxiety 400 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antiarrhythmic 400 mg/day * Antiarthritic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antiasthmatic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antiatherosclerotic 400 mg/day * Anticephalagic * AntiCFS * Anticlimacteric 500-750 mg/day * Anticonvulsant Facciola, S. 1998. Cornucopia - A Source Book of Edible Plants. Kampong Publications, Vista CA. 713 pp. Anticoronary 400 mg/day Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Antidepressant Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antidiabetic 400-800 mg/man/day * Antidysmenorrheic 100 mg 4 x/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antiendometriotic 500 mg/day * Antienterotic * Antiepileptic 450 mg/day * Antifatigue * Antifibromyalgic 200-300 mg 3x/day * Antigastrotic * Antiglaucomic * Antihyperkinetic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antihypertensive * Antihypoglycemic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antiinflammatory 100 mg 4 x/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antiinsomniac Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antilithic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). AntiLyme 400-1,000 mg * Antimastalgic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antimenopausal 500-750 mg/day * Antimigraine 200 mg/day/man Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antimitral-valve-prolapse * AntiMS * Antinephrolytic * Antineurotic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antiosteoporotic 500-1,000 mg/day/wmn/orl * Antiplaque 500-1,000 mg/day * AntiPMS 400-800 mg/day/wmn/orl * AntiPMS 400-800 mg/day/wmn orl * AntiRaynaud's 280-350 mg/day * Antiretinopathic 400 mg/day Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Antispasmodic * Antispasmophilic 500 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antistress 500-750 mg/day * Antistroke 400 mg/day Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Antisyndrome-X 400 mg/man/day Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Anxiolytic 500-750 mg/day * Calcium-Antagonist * Cardioprotective * CNS-Depressant Facciola, S. 1998. Cornucopia - A Source Book of Edible Plants. Kampong Publications, Vista CA. 713 pp. Diuretic * Hypocholesterolemic 400 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Hypotensive 260-500 mg/day * Immunomodulator * Insulinogenic 400 mg/day Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Laxative 300-500 mg/day * Litholytic * Myorelaxant 100 mg 4 x/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Neurotransmitter * Tranquilizer 500-750 mg/day * Uterorelaxant 100 mg 4 x/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Vasodilator *
14	MANGANESE	Leaf	28.0	55.0	-0.37	*
Antialcoholic Forest H. Nielsen, USDA, Grand Forks, various publications. Antianemic Martindale's 28th Antiarthritic * Antidiabetic 3-5 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antidiabetic 10-30 mg/man/day * Antidiscotic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antidyskinetic Martindale's 28th Antiepileptic 450 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antiosteoporotic * Antiototic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antioxidant * AntiPMS * Antisyndrome-X 10-30 mg/man/day Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Hypoglycemic 10-30 mg/man/day *
21	METHYL-SALICYLATE	Leaf	--	1300.0	-0.32	*
Allergenic Martindale's 28th Analgesic * Anaphrodisiac * Antiinflammatory Planta Medica, 56(6): 660, 1990. Antioxidant * Antipyretic * Antiradicular O'Connell, M.J., Webster, N.R. 1989. Hyperoxia and salicylate metabolism in rats. J. Pharm. Pharmacol. 42: 205-206, 1990. Antirheumatalgic Martindale's 28th Antiseptic * Antitartar * Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Carminative * Counterirritant Merck 11th Edition Dentifrice Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry FLavor FEMA 70-8,000 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Fungicide * Herpetifuge * Insectifuge Hardie, J., Isaacs, R., Pickett,* J.A., Wadhams, L.J., and Woodcock, C.M. 1994. Methyl Salicylate and (-)-(1R,5S)-Myrtenal are Plant-Derived Repellents for Black Bean Aphid, Aphis Fabae Scop. (Homoptera: Aphididae). J. of Chemical Ecology, 20(11):2847. Insectiphile * Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Pesticide *
0	OMBUIN-3-O-RUTINOSIDE	Leaf	--	--	--	*
0	PALMITYL-BETA-AMYRIN	Leaf	--	--	--	*
14	POTASSIUM	Leaf	6600.0	7800.0	-1.00	*
Angiotensin-Receptor-Blocker * Antiarrhythmic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antidepressant Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antifatigue Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antihypertensive * Antispasmodic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antistroke * Anxiolytic * Beta-Blocker * Cardioprotective 3,000-5,000 mg * Cardiotoxic 18,000 mg/man/day * Diuretic * Hypotensive * Vasodilator *

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^*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.

Plant Erythroxylum novogranatense (Erythroxylaceae)

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