Cnicus benedictus | Plant | Dr. Duke's Phytochemical and Ethnobotanical Databases

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Common name(s)

Blessed Thistle

How used

GRAS

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Activities: 585

Chemicals w/Activities: 80

All Chemicals: 141

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Exclude ubiquitous chemicals - View the list of ubiquitous chemicals

List of all chemical
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# Activity	Chemical Name	Part Filter by plant part	Low PPM	High PPM	StdDev	^*Reference
30	(+)-CATECHIN	Plant	--	--	--	Jim Duke's personal files.
ACE-Inhibitor 0.24 mg/ml rbt (weak activity) * ACE-Inhibitor IC50=0.155 mM/l * Antiaggregant IC68=200 ug/ml * Anticoagulant * Anticomplementary 1/2 aspirin * AntiHIV EC50=4 ug/ml * Antiinflammatory IC50=40-943 uM (cf indomethacin IC50=1 uM) * Antimutagenic ID50=50-100 nM Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp. Antioxidant * Antiperoxidant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antiprostaglandin IC50=40-943 uM (cf indomethacin IC50=1 uM) * Antiradicular Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antiulcer * Beta-Adrenergic Receptor Blocker 10 uM (weak activity) Zhu, M., Phillipson, J. D., Greengrass, P. M., Bowery, N. E., Cai, Y. 1997. Plant Polyphenols: Biologically Active Compounds or Non-Selective Binders to Protein? Phytochemistry, 44(3): 441-447. cAMP-Phosphodiesterase-Inhibitor * Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Cardiotonic * COX-1-Inhibitor IC50=183-279 uM (cf indomethacin IC50=1 uM) * COX-2-Inhibitor IC50=546-5,910 uM (cf indomethacin IC50=1 uM) * Cyclooxygenase-Inhibitor * Cytotoxic TC50=>100 ug/ml * Dermatitigenic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Hemostat Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Hepatoprotective Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Immunostimulant Economic & Medicinal Plant Research, 1: 124. Neuroprotective 1-10 uM * NO-Inhibitor IC11=250 uM * Phagocytotic Economic & Medicinal Plant Research, 1: 124. Vasoconstrictor Leung, A.Y., Encyclopedia of Common Natural Ingredients Used in Food, Drugs, and Cosmetics, John Wiley & Sons, New York, 1980. Xanthine-Oxidase-Inhibitor Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
0	2-ACETYLNORTRACHELOSIDE	Plant	--	--	--	*
3	ABSINTHIN	Plant	--	--	--	Jim Duke's personal files.
Insecticide Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands. Larvicide Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands. Toxic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
0	ALPHA-AMYRENONE	Shoot	--	--	--	Jim Duke's personal files.
10	ALPHA-AMYRIN	Shoot	--	--	--	Jim Duke's personal files.
Analgesic * Antiedemic IC43=40 mg/kg ipr rat * Antiinflammatory IC71=1,000 ppm orl * Antinociceptive * Antitumor * Antiulcer * Cytotoxic 50-400 * Gastroprotective * Hepatoprotective * Insectifuge *
10	ALPHA-AMYRIN	Plant	--	--	--	*
Analgesic * Antiedemic IC43=40 mg/kg ipr rat * Antiinflammatory IC71=1,000 ppm orl * Antinociceptive * Antitumor * Antiulcer * Cytotoxic 50-400 * Gastroprotective * Hepatoprotective * Insectifuge *
2	ALPHA-AMYRIN-ACETATE	Plant	--	--	--	Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Antiinflammatory * Antinociceptive *
0	ALPHA-AMYRINE	Plant	--	--	--	Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
5	ALUMINUM	Plant	11.3	85.0	-0.59	*
Antisilicotic Medicinal and Poisonous Plants of the Tropics. Leeuwenberg, A.J.M., ed. Pudoc, Wageningen. 1987. Antivaginitic Martindale's 28th Candidicide Martindale's 28th Encephalopathic Martindale's 29th Pesticide *
0	AMYRENONE	Plant	--	--	--	Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
0	ANABSINTHIN	Plant	--	--	--	Jim Duke's personal files.
4	APIGENIN-7-GLYCOSIDE	Plant	--	--	--	List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Anticomplementary * Antiinflammatory Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp. Antispasmodic Planta Medica, 56: 638, 1990. Nodulation-Signal Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
22	ARCTIGENIN	Plant	--	--	--	*
AntiHIV IC85=0.5 uM * AntiHIV IC65=0.27 uM * Antiintegrase * Antileukemic IC50=0.067-0.53 ug/ml Life Sciences 55: 1061. Antileukemic 0.2-1.4 uM * Antilymphomic ED50=0.53-2 uM * Antiproliferant IC74=5 uM * Antiproliferant IC88=20 uM * AntiTNF * Antitopoisomerase-II * Antitumor Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Antitumor (Liver) IC50=3.5 uM * Antiviral * Cytotoxic * Differentiator 0.5-50 uM * Differentiator IC60=10 uM * Differentiator IC79=50 uM * HIV-RT-Inhibitor IC69=0.27 uM * Immunomodulator * Immunostimulant * Pesticide * Phosphodiesterase-Inhibitor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
4	ARCTIIN	Seed	--	--	--	List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Anticancer IC50=8.9 uM * Antitumor (Liver) IC50=4.9 uM * Diuretic * Narcotic *
0	ARTEMISIFOLIN	Plant	--	--	--	Jim Duke's personal files.
1	ARTEMISIIFOLIN	Plant	--	--	--	Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Antitumor CRC Handbook of Medicinal Herbs and/or CRC Handbook of Proximate Analyses
112	ASCORBIC-ACID	Plant	4.0	30.0	-0.59	*
Acidulant FEMA 6,000 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Aldose-Reductase-Inhibitor Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Analgesic 5-10 g/day * Angiotensin-Receptor-Blocker * AntiAGE 2,000 mg/day Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Antiaggregant Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Antiaging 400 mg/day * Antiallergic * Antialzheimeran 2,000-6,000 mg/day * Antiarthritic 0.2-1 g/day * Antiasthmatic 1,000 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antiatherosclerotic * Antibacterial Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Anticataract 400 mg/day Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Anticataract 1 g 3x/day * Anticataract 350 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Anticervicaldysplasic 1,000-2,000 mg/day * AntiCFS 500-1,000 mg * Anticlimacteric 500-5,000 mg/day * Anticold 1-2 g/man/day * AntiCrohn's 50-100 mg/day/orl/man Martindale's 29th AntiCTS 1,000 mg 3x/day * Antidecubitic 500 mg/man/2x/day Martindale's 28th Antidementia * Antidepressant 2,000 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antidiabetic Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Antidote (Aluminum) Economic & Medicinal Plant Research, 6: 189. Antidote (Cadmium) Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antidote (Lead) Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antidote (Paraquat) Martindale's 28th Antieczemic 3.5-5 g/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antiedemic 1 g/man/day Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antiencephalitic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antiendometriotic 2,000 mg/day * Antifatigue 500-1,000 mg * Antifibrotic 1,000-2,000 mg * Antigallstone 1,000-3,000 mg/day * Antigastritic * Antigingivitic * Antiglaucomic 2 g/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antihangover 1,000 mg * Antihemorrhagic 1 g/man/day Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antihepatitic 2-6 g/man/day Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antihepatotoxic Economic & Medicinal Plant Research, 6: 189. Antiherpetic 1-5 g/day * Antihistaminic 2 g/day orl man * Antihypertensive * Antiinfertility 1 g/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antiinflammatory Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antilepric 1.5 g/man/day Martindale's 28th Antilithic 1,000-3,000 mg/day * AntiLyme 500-2,000 mg * Antimaculitic * Antimeasles Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antimenopausal 500-5,000 mg/day * Antimigraine Martindale's 29th Antimutagenic Economic & Medicinal Plant Research, 6: 235. Antineuramidase * Antinitrosic 1 g/man/day Martindale's 28th Antiobesity 1 g 3x/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antiorchitic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antiosteoarthritic 1 g 2x/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antiosteoporotic 500 mg/day * Antioxidant 100 ppm * Antiparkinsonian 1 g 2-3x/day * Antiparotitic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antiperiodontitic 1 g 2x/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antipneumonic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antipodriac Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antipoliomyelitic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antipyretic Economic & Medicinal Plant Research, 6: 189. Antiradicular Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 AntiRaynaud's 500 mg 1-2x/day * Antiretinotic * Antirheumatic * Antirhinitic 1,000 mg 3x/day * Antiscorbutic 10 mg/man/day Martindale's 28th Antiseptic MIC=3.3-217 mg/ml Martindale's 28th Antiseptic 4-8 g/day Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Antishingles Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antispasmodic 500-5,000 mg/day * Antistress 500-1,000 mg * Antisyndrome-X 1-4 g/day Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Antitumor (Gastric) * Antitumor (Lung) * Antiulcer * Antiviral 1-5 g/day * Apoptotic 1-10 mM * Asthma-preventive 1,000 mg/day/orl Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Beta-Adrenergic Receptor Blocker * Beta-Glucuronidase-Inhibitor 1.5 g/day/man * Calcium-Antagonist * Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Cardioprotective * Cold-preventive 1-2 g/day Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Collagenic * Detoxicant * Diuretic 700 mg/man/orl * Fistula-Preventive Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Hypocholesterolemic 300-1,000 mg/day Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Hypoglycemic Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Hypotensive 1,000 mg/man/day * Immunomodulator * Immunostimulant Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Interferonogenic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Lithogenic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Mucolytic 1 g/woman/day Martindale's 28th Pesticide * Uricosuric 4 g/man/day Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Urinary-Acidulant Martindale's 29th Vasodilator * Vulnerary Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
0	ASH	Seed	--	41000.0	-0.21	CRC Handbook of Medicinal Herbs and/or CRC Handbook of Proximate Analyses
0	ASH	Plant	17689.0	133000.0	0.22	*
7	ASTRAGALIN	Shoot	--	--	--	Jim Duke's personal files.
ACE-Inhibitor ID50=180 ug/ml rat (24 hr.) * Aldose-Reductase-Inhibitor IC30=1 uM * Aldose-Reductase-Inhibitor IC62=10 uM Shimizu, M., Ito, T., Terashima, S., Hayashi, T., Arisawa, M., Morita, N., Kurokawa, S., Ito, K., and Hashimoto, Y. 1984. Inhibition of Lens Aldose Reductase by Flavonoids. Phytochemistry, 23: 1885-1888. Antileukemic * Expectorant * Hypotensive Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990. Immunostimulant *

List of all activity chemical
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# Activity	Chemical Name	Part Filter by plant part	Low PPM	High PPM	StdDev	^*Reference

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^*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.

Plant Cnicus benedictus (Asteraceae)

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