Cinnamomum sieboldii | Plant | Dr. Duke's Phytochemical and Ethnobotanical Databases

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Common name(s)

Japanese Cinnamon

How used

Medicinal

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Activities: 210

Chemicals w/Activities: 24

All Chemicals: 36

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# Activity	Chemical Name	Part Filter by plant part	Low PPM	High PPM	StdDev	^*Reference
30	(+)-CATECHIN	Plant	--	--	--	*
ACE-Inhibitor IC50=0.155 mM/l * ACE-Inhibitor 0.24 mg/ml rbt (weak activity) * Antiaggregant IC68=200 ug/ml * Anticoagulant * Anticomplementary 1/2 aspirin * AntiHIV EC50=4 ug/ml * Antiinflammatory IC50=40-943 uM (cf indomethacin IC50=1 uM) * Antimutagenic ID50=50-100 nM Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp. Antioxidant * Antiperoxidant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antiprostaglandin IC50=40-943 uM (cf indomethacin IC50=1 uM) * Antiradicular Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antiulcer * Beta-Adrenergic Receptor Blocker 10 uM (weak activity) Zhu, M., Phillipson, J. D., Greengrass, P. M., Bowery, N. E., Cai, Y. 1997. Plant Polyphenols: Biologically Active Compounds or Non-Selective Binders to Protein? Phytochemistry, 44(3): 441-447. cAMP-Phosphodiesterase-Inhibitor * Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Cardiotonic * COX-1-Inhibitor IC50=183-279 uM (cf indomethacin IC50=1 uM) * COX-2-Inhibitor IC50=546-5,910 uM (cf indomethacin IC50=1 uM) * Cyclooxygenase-Inhibitor * Cytotoxic TC50=>100 ug/ml * Dermatitigenic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Hemostat Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Hepatoprotective Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Immunostimulant Economic & Medicinal Plant Research, 1: 124. Neuroprotective 1-10 uM * NO-Inhibitor IC11=250 uM * Phagocytotic Economic & Medicinal Plant Research, 1: 124. Vasoconstrictor Leung, A.Y., Encyclopedia of Common Natural Ingredients Used in Food, Drugs, and Cosmetics, John Wiley & Sons, New York, 1980. Xanthine-Oxidase-Inhibitor Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
38	(-)-EPICATECHIN	Plant	--	--	--	*
5-Lipoxygenase-Inhibitor IC50=22-50 uM/l * ACE-Inhibitor IC50=0.216 mM/l * ACE-Inhibitor 0.5 mg/ml rbt (weak activity) * Allelochemic Hanke, F. J., Natural Products as a Resource for Biologically Active Compounds, Thesis, U. Cal (Santa Cruz), 1986, 252 pp Antiaggregant * Antianaphylactic * Antibacterial * Antidiabetic 30 mg/kg rat * AntiEBV Economic & Medicinal Plant Research, 6: 189. Antihepatitic Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart. AntiHIV EC50=2 ug/ml * Antihyperglycemic * Antiinflammatory * Antileukemic Economic & Medicinal Plant Research, 6: 189. Antileukotriene * Antilipoperoxidant * Antimutagenic * Antioxidant IC50=6.3 ug/ml * Antiperoxidant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antiviral EC50=2 ug/ml * Beta-Adrenergic Receptor Blocker 10 uM Zhu, M., Phillipson, J. D., Greengrass, P. M., Bowery, N. E., Cai, Y. 1997. Plant Polyphenols: Biologically Active Compounds or Non-Selective Binders to Protein? Phytochemistry, 44(3): 441-447. Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Cardiotonic * Choline-Sparing * COMP-Inhibitor Dullo, A. G., et al. 1999. Efficacy of a green tea extract rich in catechin polyphenols and caffeine in increasing 24-h energy expenditure and fat oxidation in humans. Am. J. Clinical Nutrition, 70: 1040-1045. Cytotoxic TC50=>100 ug/ml * Hypocholesterolemic * Hypoglycemic * Immunostimulant * Insulinogenic Economic & Medicinal Plant Research, 6: 170. Lipoxygenase-1-Inhibitor IC50=60 mM * Lipoxygenase-Inhibitor IC50=140 uM Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp. Lipoxygenase-Inhibitor IC97=5 mM Oszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690. Pancreatogenic * Pesticide * Reverse-Transcriptase-Inhibitor 10 ng/ml McKenna, D. J., Hughes, K., and Jones, K. 2000. Green Tea Monograph. Alternative Therapies, 6(3): 61-82. Vasodilator uM McKenna, D. J., Hughes, K., and Jones, K. 2000. Green Tea Monograph. Alternative Therapies, 6(3): 61-82. Xanthine-Oxidase-Inhibitor IC50=>40 Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
0	BARIUM	Bark	--	55.0	-0.57	*
0	BARIUM	Root Bark	--	80.0	--	*
0	BROMINE	Bark	--	--	--	*
0	BROMINE	Root Bark	--	5.0	--	*
28	CALCIUM	Root Bark	--	9000.0	-0.79	*
Antiallergic 500 mg/day * Antianxiety Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antiarrhythmic 500-1,500 mg * Antiarthritic 1,000 mg/day * Antiatherosclerotic 500 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Anticlimacteric 1,000-1,500 mg/day * Antidepressant Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antidote (Aluminum) Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antidote (Lead) Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antihyperkinetic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antihypertensive * Antiinsomniac Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antimenopausal 1,000-1,500 mg/day * Antiobesity * Antiosteoporotic 500-2,000 mg/day * Antiperiodontitic 750 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. AntiPMS 1 g/day * Antirheumatic 1,000 mg/day * Antistress 500-1,500 mg/day * Antitic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Anxiolytic 500-1,500 mg/day * Calcium-Channel-Blocker * Diuretic * Hypocholesterolemic 500 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Hypotensive 1 g/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Laxative 1,000-1,200 mg * Tranquilizer 500-1,500 mg/day * Vasodilator *
28	CALCIUM	Bark	--	14000.0	-0.45	*
Antiallergic 500 mg/day * Antianxiety Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antiarrhythmic 500-1,500 mg * Antiarthritic 1,000 mg/day * Antiatherosclerotic 500 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Anticlimacteric 1,000-1,500 mg/day * Antidepressant Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antidote (Aluminum) Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antidote (Lead) Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antihyperkinetic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antihypertensive * Antiinsomniac Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antimenopausal 1,000-1,500 mg/day * Antiobesity * Antiosteoporotic 500-2,000 mg/day * Antiperiodontitic 750 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. AntiPMS 1 g/day * Antirheumatic 1,000 mg/day * Antistress 500-1,500 mg/day * Antitic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Anxiolytic 500-1,500 mg/day * Calcium-Channel-Blocker * Diuretic * Hypocholesterolemic 500 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Hypotensive 1 g/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Laxative 1,000-1,200 mg * Tranquilizer 500-1,500 mg/day * Vasodilator *
7	CHLORINE	Bark	--	200.0	0.09	*
Antibacterial Martindale's 29th Antiherpetic Martindale's 29th Antiseptic Martindale's 29th Antiviral Martindale's 29th Candidicide Martindale's 29th Fungicide Martindale's 29th Pesticide *
7	CHLORINE	Root Bark	--	300.0	--	*
Antibacterial Martindale's 29th Antiherpetic Martindale's 29th Antiseptic Martindale's 29th Antiviral Martindale's 29th Candidicide Martindale's 29th Fungicide Martindale's 29th Pesticide *
24	CHROMIUM	Root Bark	--	2.0	--	*
Amphiglycemic? Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antiacne * AntiAGE 200-1,000 ug Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Antiaging 200-1,000 ug Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Antiatherosclerotic 20 ug/day * AntiCFS 200 ug * Anticorneotic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antidiabetic 200-1,000 ug * Antidote (Lead) Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antifatigue 200 ug * Antiglycosuric 200-1,000 ug * Antiobesity 200-1,000 ug Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Antisyndrome-X 200-800 ug Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Antitriglyceride 200-1,000 ug Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Antitriglyceride 20 ug/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Cardioprotective * Energizer * Hypocholesterolemic 200-1,000 ug Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Hypocholesterolemic 20 ug/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Hypoglycemic 200-1,000 ug Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Hypotensive 200-1,000 ug Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Immunomodulator * Insulinogenic * Memorigenic *
12	COPPER	Bark	--	7.0	0.07	*
Antianemic * Antiarthritic * Antidiabetic 2-4 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antifatigue * Antiinflammatory Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antinociceptive Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antiosteoporotic * Cardioprotective * Contraceptive Martindale's 28th Hypocholesterolemic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Immunomodulator * Schizophrenigenic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
12	COPPER	Root Bark	--	9.0	-0.15	*
Antianemic * Antiarthritic * Antidiabetic 2-4 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antifatigue * Antiinflammatory Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antinociceptive Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antiosteoporotic * Cardioprotective * Contraceptive Martindale's 28th Hypocholesterolemic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Immunomodulator * Schizophrenigenic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
40	EPICATECHIN	Plant	--	--	--	*
Allelochemic IC100=1 mM Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp. Anabolic * Antiaggregant IC94=200 ug/ml * Antianaphylactic * Antibacterial MIC=>1,000 ug/ml * Anticomplementary 1/2 aspirin * Antidiabetic 30 mg/kg rat * AntiEBV Economic & Medicinal Plant Research, 6: 189. Antifeedant * Antihepatitic Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart. AntiHIV EC50=2 ug/ml * Antihyperglycemic * Antiinflammatory * Antileukemic IC50=>10 ug/ml * Antilipoperoxidant * Antimutagenic * Antioxidant 2.5 x Vit. E * Antioxidant IC50=6.3 ug/ml Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990. Antioxidant IC50=10.2 uM * Antioxidant 3/4 quercetin * Antiperoxidant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antiviral * Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Cardiotonic * Choline-Sparing Singleton, V.L. 1981. Naturally Occurring Food Toxicants: Phenolic Substances of Plant Origin Common in Foods. Advances in Food Research 27: 149-217. Hepatotropic * Hypocholesterolemic Singleton, V.L. 1981. Naturally Occurring Food Toxicants: Phenolic Substances of Plant Origin Common in Foods. Advances in Food Research 27: 149-217. Hypoglycemic * Insulinogenic Economic & Medicinal Plant Research, 6: 170. Interleukin-1-alpha-Inhibitor * Interleukin-6-mRNA-Inhibitor * Lipoxygenase-Inhibitor IC50=140 uM Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp. Lipoxygenase-Inhibitor IC97=5 mM Oszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690. NO-Inhibitor * Pancreatogenic * Peroxynitrite-Scavenger IC50=0.181 ug/ml * Pesticide * Propecic * TNF-alpha-Inhibitor * Xanthine-Oxidase-Inhibitor IC50=>40 *
12	IODINE	Bark	--	--	--	*
Acnegenic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antibacterial * Antigoiter Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antiseptic * Antithyrotoxic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antiviral * Dermatitigenic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Fungicide * Goitrogenic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Hyperthyroid >1 mm/day/diet * Protisticide * Thyrotropic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
12	IODINE	Root Bark	--	4.0	--	*
Acnegenic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antibacterial * Antigoiter Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antiseptic * Antithyrotoxic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antiviral * Dermatitigenic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Fungicide * Goitrogenic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Hyperthyroid >1 mm/day/diet * Protisticide * Thyrotropic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
6	IRON	Root Bark	--	200.0	-0.40	*
Antiakathisic Martindale's 29th Antianemic Martindale's 29th Anticanker * Anticheilitic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antimenorrhagic 100 mg/day/wmn/orl Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Prooxidant *
0	LEAD	Bark	--	8.0	--	*
0	LEAD	Root Bark	--	9.0	--	*
14	MANGANESE	Root Bark	--	220.0	2.11	*
Antialcoholic Forest H. Nielsen, USDA, Grand Forks, various publications. Antianemic Martindale's 28th Antiarthritic * Antidiabetic 3-5 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antidiabetic 10-30 mg/man/day * Antidiscotic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antidyskinetic Martindale's 28th Antiepileptic 450 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antiosteoporotic * Antiototic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antioxidant * AntiPMS * Antisyndrome-X 10-30 mg/man/day Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Hypoglycemic 10-30 mg/man/day *

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^*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.

Plant Cinnamomum sieboldii (Lauraceae)

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