Chemical ETOPOSIDE | Dr. Duke's Phytochemical and Ethnobotanical Databases

Chemical ID

ETOPOSIDE

Ubiquitous

No

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity	Dosage	Reference
Anaphylactic	not available	Martindale's 29th
Anticancer	not available	Duke, 1992 *
AntiKaposi's	not available	Martindale's 29th
Antileukemic	IC50=0.014 ug/ml	Life Sciences 55: 1061.
Antileukemic	not available	Duke, 1992 *
Antilymphomic	not available	Duke, 1992 *
Antimitotic	not available	Martindale's 29th
Antisarcomic	not available	Martindale's 29th
Antitumor	not available	Merck 11th Edition
Antiviral	not available	Duke, J. A. Writeups or information summaries on approximately 2,000 economic plants, USDA, ARS, Beltsville, MD 20705.
AZT-Synergist	not available	Duke, J. A. Writeups or information summaries on approximately 2,000 economic plants, USDA, ARS, Beltsville, MD 20705.
Cytotoxic	not available	Duke, 1992 *
DNA-Topoisomerase-Inhibitor	not available	Duke, 1992 *
Hypotensive	not available	Martindale's 29th
Myelosuppressant	not available	Martindale's 29th
Semisynthetic	not available	Duke, 1992 *
Topoisomerase-II-Inhibitor	2-50 uM	Duke, 1992 *
Topoisomerase-II-Inhibitor	ID50=50 uM	Duke, 1992 *
Topoisomerase-II-Inhibitor	IC50=59.2 uM	Terada, T., et al. 1992. Antitumor Agents. I. DNA Topoisomerase II Inhibitory Activity and the Structural Relationship of Podophyllotoxin Derivatives as Antitumor Agents. Chem Pharm Bull, 40: 2720-2727.
Topoisomerase-II-Inhibitor	10 ug/ml	Huff, A. C., Kreuzer, K. N. 1990. Evidence for a Common Mechanism of Action for Antitumor and Antibacterial Agents That Inhibit Type II DNA Topoisomerases. J Biol Chem, 265: 20496-20505.