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Chemical CINCHONINE

Chemical ID

CINCHONINE

Ubiquitous

No

List of known dosages
Dosage
LD50=152 (ipr rat)

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity Sort descending	Dosage	Reference
Antiaggregant	IC50=125-180 uM	Duke, 1992 *
Antimalarial	LD50=152 (ipr rat)	Merck 11th Edition
Antipyretic	not available	=ICMR(Indian Council of Medical Research).1976.Medicinal Plants of India.Vol.1.Indian Council of Med. Res.Cambridge Printing Works, New Delhi.487 pp;ICMR.1987.Medicinal Plants of India.Vol.2.Indian Council of Med. Res.Cambr. Printing Works,New Delhi.600pp
MDR-Inhibitor	250 mg/kg igs rat	Genne, P., Duchamp, O., Solary, E., Magnette, J., Belon, J. P., Chauffert, B. 1995. Cinchonine Per OS: Efficient Circumvention of P-Glycoprotein-Mediated Multidrug Resistance. Anticancer Drug Design, 10(2): 103-118.
MDR-Inhibitor	5 uM	Duke, 1992 *
PAF-Inhibitor	IC50=125-180 uM	Duke, 1992 *
Pesticide	not available	Duke, 1992 *

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