An official website of the United States government.

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

Chemical SAFROLE

Chemical ID
SAFROLE
Ubiquitous
No
List of known dosages
Dosage Reference
LD50=1,950 (orl rat)
LD50=2,350 (orl mus) Merck 11th Edition
List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity Dosage Reference
Irritant not available Rinzler, C. A. 1990. The Complete Book of Herbs, Spices and Condiments. Facts on File, New York. 199 pp.
Mutagenic not available Duke, 1992 *
Nematicide MLC=1 mg/ml Shoyakugaku Zasshi, 44: 183.
Neurotoxic not available R.J. Hixtable (Huxtable, R.J. (as T. Max). 1992. This and That:The Essential Pharmacology of Herbs and Spices. Tips 13:15-20 Huxtable, R.J. 1992b. The Myth of Benficent Nature. The Risk of Herbal Preparations. Anns. Intern. Med. 117(2):165-6; Huxtable, R.
Pediculicide not available Merck 11th Edition
Perfumery not available Merck 11th Edition
Pesticide not available Duke, 1992 *
Psychoactive not available R.J. Hixtable (Huxtable, R.J. (as T. Max). 1992. This and That:The Essential Pharmacology of Herbs and Spices. Tips 13:15-20 Huxtable, R.J. 1992b. The Myth of Benficent Nature. The Risk of Herbal Preparations. Anns. Intern. Med. 117(2):165-6; Huxtable, R.
Tremorigenic not available Duke, 1992 *
List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name Plant Part Low Parts Per Million High Parts Per Million Standard Deviation Reference
Agastache rugosa Essential Oil not available not available not available Jim Duke's personal files.
Anethum graveolens Plant 125.0 360.0 0.6 Duke, 1992 *
Anethum graveolens Seed Essent. Oil not available not available not available Duke, 1992 *
Angelica sinensis Root Essent. Oil not available not available not available Jim Duke's personal files.
Angelica sinensis Root not available not available not available Pedersen, M. 1987. Nutritional Herbology. Pederson Publishing. Bountiful, Utah. 377 pp.
Asiasarum heterotropoides Root not available not available not available Duke, 1992 *
Asiasarum sieboldii Root not available not available not available Duke, 1992 *
Camellia sinensis Leaf not available not available not available Duke, 1992 *
Cananga odorata Flower not available not available not available Duke, 1992 *
Chenopodium ambrosioides Plant not available not available not available Duke, 1992 *
Cinnamomum aromaticum Plant not available not available not available Duke, 1992 *
Cinnamomum camphora Leaf not available not available not available Duke, 1992 *
Cinnamomum verum Plant not available not available not available Duke, 1992 *
Cinnamomum verum Leaf not available not available not available Wealth of India.
Cinnamomum verum Bark not available not available not available Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Cinnamomum verum Leaf Essent. Oil 6500.0 23000.0 not available Duke, 1992 *
Cinnamomum verum Bark Essent. Oil not available not available not available Duke, 1992 *
Cinnamomum verum Stem Bark not available not available not available Duke, 1992 *
Cinnamomum verum Root Bark not available not available not available Duke, 1992 *
Ephedra sinica Shoot not available 2.0 not available Duke, 1992 *