Chemical PODOPHYLLOTOXIN

List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)

Activity Sort descending	Dosage	Reference
Abortifacient	not available	Duke, 1992 *
Anticondylomata	not available	Martindale's 29th
Antifertility	not available	Pei-Gen, X., and Nai-Gong, W. Can ethnopharmacology contribute to the development of anti-fertility drugs? Journal of Ethnopharmacology, 32: 167-177, 1991.
Antiherpetic	IC88=414 ppb	Bedows, E. and Hatfield, G.M. An Investigation of the Antiviral Activity of Podophyllum peltatum. J. Nat. Prod. 45: 725.
Antileukemic	5.4 ppm	Duke, 1992 *
Antimeasles	not available	Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
Antimelanomic	ED50=>20 ug/ml	J. Ethnopharmacology, 32: 117.
Antimitotic	not available	Wagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
Antisarcomic	ED50=0.012 ug/ml	J. Ethnopharmacology, 32: 117.
Antitumor	2 ppm iv	Duke, 1992 *
Antitumor (Breast)	ED50=0.041 ug/ml	J. Ethnopharmacology, 32: 117.
Antitumor (Colon)	ED50=0.011 ug/ml	J. Ethnopharmacology, 32: 117.
Antitumor (Lung)	ED50=0.0181 ug/ml	J. Ethnopharmacology, 32: 117.
Antiviral	IC88=1 uM	Bedows, E. and Hatfield, G. M. An investigation of the antiviral activity of Podophyllum peltatum, J. Nat. Prod., 45(6), 1982, 725-9.
Cathartic	not available	Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Embryocide	not available	Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Fungicide	not available	Duke, 1992 *
Herbicide	50 ppm	Duke, 1992 *
Insecticide	1-20 ppm	Duke, 1992 *
Irritant	not available	Jim Duke's personal files.