Chemical IMPERATORIN | Dr. Duke's Phytochemical and Ethnobotanical Databases

Chemical ID

IMPERATORIN

Ubiquitous

List of known dosages
Dosage	Reference
LDlo=600 (par mus)
LD50=300-600 mg/kg (ipr mus)	Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin.

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity	Dosage	Reference
Antiaflatoxin	0.7 ppm	Duke, 1992 *
Antiaflatoxin	IC50=2.66 uM	Duke, 1992 *
Antiaggregant	not available	Duke, 1992 *
Antialopecic	not available	Martindale's 28th
Anticonvulsant	not available	Duke, 1992 *
Antiinflammatory	not available	Duke, 1992 *
Antileukodermic	not available	Duke, 1992 *
Antimitotic	5-25 ug/ml	Gawron, A. and Glowniak, K. 1987. Cytostatic Activity of Coumarins in vitro. Planta Medica 1987: 526.
Antimutagenic	not available	Saqib, Q. N., Hui, Y. H., Anderson, J. E. and McLaughlin, J. L. 1990. Bioactive Furanocoumarins from the Berries of Zanthoxylum americanum. Phytotherapy Research 4(6): 216-219.
Antiplatelet	not available	Duke, 1992 *
Antitumor-Promoter	IC86=50 ug/ml	Duke, 1992 *
Antivitiligic	not available	Duke, 1992 *
Bufocide	not available	Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Calcium-Antagonist	IC50=4 ug/ml	Duke, 1992 *
Calcium-Antagonist	31.6 ug/ml gpg	Duke, 1992 *
Cancer-Preventive	5-25 ug/ml	Gawron, A. and Glowniak, K. 1987. Cytostatic Activity of Coumarins in vitro. Planta Medica 1987: 526.
Cytochrome-P450-Inhibitor	2 nM	Duke, 1992 *
DME-Inhibitor	IC50=116 uM	Advance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 134.
Hepatoprotective	IC50=2.66 uM	Duke, 1992 *
Hepatoprotective	0.7 ppm	Duke, 1992 *

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List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name	Plant Part	Low Parts Per Million	High Parts Per Million	Standard Deviation	Reference
Glehnia littoralis	Root	not available	not available	not available	Duke, 1992 *
Levisticum officinale	Fruit	not available	13.0	-0.4	Abstract (See species file)
Pastinaca sativa	Leaf	not available	not available	not available	Duke, 1992 *
Pastinaca sativa	Root	not available	1700.0	not available	Duke, 1992 *
Pastinaca sativa	Seed	not available	not available	not available	Duke, 1992 *
Petroselinum crispum	Fruit	1.0	6.0	-0.7	Duke, 1992 *
Petroselinum crispum	Leaf	not available	0.5	not available	Duke, 1992 *
Peucedanum ostruthium	Plant	not available	not available	not available	Duke, 1992 *
Pimpinella anisum	Leaf	not available	not available	not available	Duke, 1992 *
Zanthoxylum americanum	Fruit	5.0	19.0	-0.1	Duke, 1992 *