Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture

Chemical IMPERATORIN

Chemical ID
IMPERATORIN
Ubiquitous
No
List of known dosages
Dosage Reference
LDlo=600 (par mus)
LD50=300-600 mg/kg (ipr mus) Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin.

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity Dosage Reference
Antiaflatoxin 0.7 ppm *
Antiaflatoxin IC50=2.66 uM *
Antiaggregant *
Antialopecic Martindale's 28th
Anticonvulsant *
Antiinflammatory *
Antileukodermic *
Antimitotic 5-25 ug/ml Gawron, A. and Glowniak, K. 1987. Cytostatic Activity of Coumarins in vitro. Planta Medica 1987: 526.
Antimutagenic Saqib, Q. N., Hui, Y. H., Anderson, J. E. and McLaughlin, J. L. 1990. Bioactive Furanocoumarins from the Berries of Zanthoxylum americanum. Phytotherapy Research 4(6): 216-219.
Antiplatelet *
Antitumor-Promoter IC86=50 ug/ml *
Antivitiligic *
Bufocide Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Calcium-Antagonist IC50=4 ug/ml *
Calcium-Antagonist 31.6 ug/ml gpg *
Cancer-Preventive 5-25 ug/ml Gawron, A. and Glowniak, K. 1987. Cytostatic Activity of Coumarins in vitro. Planta Medica 1987: 526.
Cytochrome-P450-Inhibitor 2 nM *
DME-Inhibitor IC50=116 uM Advance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 134.
Hepatoprotective IC50=2.66 uM *
Hepatoprotective 0.7 ppm *
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List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name Plant Part Low Parts Per Million High Parts Per Million Standard Deviation Reference
Ammi majus Seed 100.0 8000.0 1.1 *
Anethum graveolens Seed Essent. Oil *
Angelica archangelica Fruit 66.0 1.9 *
Angelica archangelica Plant *
Angelica archangelica Shoot *
Angelica archangelica Seed 50.0 5000.0 0.2 *
Angelica archangelica Root *
Angelica dahurica Root *
Apium graveolens Seed Wealth of India.
Apium graveolens Root *
Apium graveolens Leaf *
Chenopodium album Plant *
Citrus aurantiifolia Fruit Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Citrus limon Fruit *
Citrus limon Fruit Essent. Oil Jim Duke's personal files.
Citrus meyerii Seed Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Foeniculum vulgare Fruit 0.0 3.0 -0.8 *
Foeniculum vulgare Seed 0.0 3.0 -1.3 *
Fragaria spp Leaf Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Glehnia littoralis Rhizome *