Chemical GENISTEIN | Dr. Duke's Phytochemical and Ethnobotanical Databases

Chemical ID

GENISTEIN

Ubiquitous

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity	Dosage	Reference
NADH-Ubiquinone-Oxidoreductase-Inhibitor	not available	Duke, 1992 *
Natriuretic	not available	Duke, 1992 *
Ornithine-Decarboxylase-Inhibitor	not available	Duke, 1992 *
Peroxidase-Inhibitor	not available	Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide	not available	Duke, 1992 *
Phytoalexin	not available	Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Pituitary-sensitizer	not available	Medline (post 1990 searches filed in my computer)
PTK-Inhibitor	10-100 uM	Duke, 1992 *
Quinone-Reductase-Inducer	IC50=4.6 ug/ml	Duke, 1992 *
Topoisomerase-I-Inhibitor	IC50=250 ppm	Duke, 1992 *
Topoisomerase-I-Inhibitor	1-10 ug/ml	Okura, A., Arakawa, H., Oka, H., Yoshinari, T., Monden, Y. 1988. Effect of Genistein on Topoisomerase Activity and on the Growth of [VAL 12]HA-RAS-Transformed NIH 3T3 Cells. Biochem Biophys Res Commun, 157: 183-189.
Topoisomerase-II-Inhibitor	2-7.5 ug/ml	Duke, 1992 *
Topoisomerase-II-Inhibitor	IC50=30 ug/ml	Constantinou, A., Mehta, R., Runyan, C., Rao, K., Vaughan, A., Moon, R. 1995. Flavonoids as DNA Topoisomerase Antagonists and Poisons: Structure-Activity Relationships. J Natural Products, 58: 217-225.
Topoisomerase-II-Inhibitor	20 uM	Markovits, J., et al. 1989. Inhibitory Effects of the Tyrosine Kinase Inhibitor Genistein on Mammalian DNA Topoisomerase II. Cancer Research, 49: 5111-5117.
Topoisomerase-II-Inhibitor	IC50=1-150 uM	Duke, 1992 *
Topoisomerase-II-Poison	not available	Journal of Medicinal Food 2: 167.1999.
Trypanosomastat	not available	Medline (post 1990 searches filed in my computer)
Tyrosine-Kinase-Inhibitor	not available	Duke, 1992 *
Uterotrophic	ED50=0.5 mg/kg	Duke, 1992 *
Uterotrophic	EC50=0.1-25 uM/l	Duke, 1992 *

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List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name	Plant Part	Low Parts Per Million	High Parts Per Million	Standard Deviation	Reference
Galactia jussiaeana	Leaf Diffusate	not available	not available	not available	Duke, 1992 *
Genista clavata	Leaf	not available	not available	not available	Duke, 1992 *
Genista germanica	Leaf	not available	not available	not available	Duke, 1992 *
Genista lydia	Flower	not available	not available	not available	Duke, 1992 *
Genista ovata	Leaf	not available	not available	not available	Duke, 1992 *
Genista patula	Leaf	not available	not available	not available	Duke, 1992 *
Genista rumelica	Leaf	not available	not available	not available	Duke, 1992 *
Genista sp	Plant	not available	not available	not available	Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Genista tinctoria	Flower	not available	not available	not available	Duke, 1992 *
Glycine max	Cotyledon	28.0	59.0	not available	Duke, 1992 *
Glycine max	Endosperm	not available	267.0	not available	Duke, J. A. Writeups or information summaries on approximately 2,000 economic plants, USDA, ARS, Beltsville, MD 20705.
Glycine max	Root	not available	not available	not available	Duke, 1992 *
Glycine max	Hypocotyl	242.0	247.0	not available	Duke, 1992 *
Glycine max	Plant	not available	not available	not available	Duke, 1992 *
Glycine max	Seed	20.0	267000.0	3.3	Duke, 1992 *
Glycine max	Shoot	not available	not available	not available	Duke, 1992 *
Glycine max	Testa	5.0	15.0	not available	Duke, 1992 *
Glycine max	Embryo	not available	not available	not available	Duke, 1992 *
Glycine wightii	Leaf Diffusate	not available	5.0	-0.6	Duke, 1992 *
Glycyrrhiza glabra	Shoot	not available	not available	not available	Duke, 1992 *