Chemical GENISTEIN | Dr. Duke's Phytochemical and Ethnobotanical Databases

Chemical ID

GENISTEIN

Ubiquitous

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity	Dosage	Reference
Calcium-Antagonist	50 uM gpg	Duke, 1992 *
Cancer-Preventive	not available	Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Cardioprotective	not available	Journal of Medicinal Food 2: 163.1999.
Catechol-O-Methyltransferase-Inhibitor	not available	Duke, 1992 *
Cytotoxic	>50 ug/ml (185 uM)	Medline (post 1990 searches filed in my computer)
Cytotoxic	IC89=10 ug/ml	Planta Medica, 57: A113, 1991.
DOPA-Decarboxylase-Inhibitor	not available	Duke, 1992 *
Estrogen-Agonist	0.1-1 uM/l	Journal of Medicinal Food 2: 139.1999.
Estrogenic	EC50=0.1-25 uM/l	Duke, 1992 *
Flatulent	not available	Duke, 1992 *
Fungicide	2.5 mM	Geibel, M. 1994. Sensitivity of the Fungus Cytospora persoonii to the Flavonoids of Prunus cerasus. Phytochemistry. 38(3): 599-601. 1995.
Fungicide	ED50=50->100	Duke, 1992 *
Fungistat	IC34=200 uM	Duke, 1992 *
Histidine-Kinase-Inhibitor	IC50=110 uM	Medline (post 1990 searches filed in my computer)
Hypocholesterolemic	ED50=0.5 mg/kg	Duke, 1992 *
Immunostimulant	2-20 mg/kg orl mus	Duke, 1992 *
Lipase-Inhibitor	not available	Duke, 1992 *
MAO-Inhibitor	IC50=60-140 uM	Duke, 1992 *
MAO-Inhibitor	IC50=95	Duke, 1992 *
MDR-Inhibitor	200 uM	Castro, A. F., Altenberg, G. A. 1997. Inhibition of Drug Transport by Genistein in Multidrug-Resistant Cell Expressing P-Glycoprotein. Biochem Pharmacol, 53(1): 89-93.

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List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name	Plant Part	Low Parts Per Million	High Parts Per Million	Standard Deviation	Reference
Macrotyloma axillare	Leaf Diffusate	not available	not available	not available	Duke, 1992 *
Macrotyloma uniflora	Leaf	not available	not available	not available	Duke, 1992 *
Medicago sativa	Shoot	not available	not available	not available	Duke, 1992 *
Medicago sativa	Leaf	not available	not available	not available	Duke, 1992 *
Medicago sativa	Plant	not available	not available	not available	Duke, 1992 *
Moghania macrophylla	Wood	not available	not available	not available	Duke, 1992 *
Mucuna deeringiana	Hypocotyl	not available	not available	not available	Duke, 1992 *
Mucuna pruriens	Leaf Diffusate	not available	6.0	-0.5	Duke, 1992 *
Mucuna pruriens	Leaf Diffusate	not available	8.0	-0.3	Duke, 1992 *
Neonotonia wightii	Leaf Diffusate	not available	5.0	-0.6	Duke, 1992 *
Ononis spinosa	Root	17.0	38.0	1.0	Duke, 1992 *
Pericopsis laxiflora	Fruit	not available	not available	not available	Duke, 1992 *
Phaseolus coccineus	Plant	not available	not available	not available	J.S. Glasby Dict.Pls Containing 2ndary Metabolite. 1991.
Phaseolus coccineus	Plant	not available	not available	not available	Duke, 1992 *
Phaseolus lunatus	Leaf Diffusate	not available	not available	not available	Duke, 1992 *
Phaseolus lunatus	Leaf	not available	2300.0	-0.6	Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Phaseolus lunatus	Seed	0.0	40.1	-0.3	Duke, 1992 *
Phaseolus spp	Plant	not available	not available	not available	Duke, 1992 *
Phaseolus vulgaris	Fruit	not available	not available	not available	Duke, 1992 *
Phaseolus vulgaris	Seed	17.7	45.1	-0.3	Kaufman,PB,Duke,JA,Brielmann,H,Boik,J and Hoyt,JE. 1997. A Comparative Survey of Leguminous Plants as Sources of the Isoflavones Genistein and Daidzein: Implications For Human Nutrition and Health. Journal of Alternative & Complementary Medicine 3(1):7-12