Chemical EUGENOL | Dr. Duke's Phytochemical and Ethnobotanical Databases

Chemical ID

EUGENOL

Ubiquitous

List of known dosages
Dosage	Reference
LD50=2,680 (orl rat)	Jim Duke's personal files.
LD50=3,000 (orl mus)
LDlo=500 (orl rat)
ADI=2.5 mg/kg	Martindale's 28th

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity	Dosage	Reference
Motor-Depressant	not available	Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC
Nematicide	MLC=2,000 ug/ml	Shoyakugaku Zasshi, 44: 183.
Neurotoxic	not available	R.J. Hixtable (Huxtable, R.J. (as T. Max). 1992. This and That:The Essential Pharmacology of Herbs and Spices. Tips 13:15-20 Huxtable, R.J. 1992b. The Myth of Benficent Nature. The Risk of Herbal Preparations. Anns. Intern. Med. 117(2):165-6; Huxtable, R.
Perfumery	not available	Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide	not available	Duke, 1992 *
Prostaglandin-Synthesis-Inhibitor	1 mM rbt	Chen, S. J., Wang, M. H., Chen, I. J. 1996. Antiplatelet and Calcium Inhibitory Properties of Eugenol and Sodium Eugenol Acetate. Gen Pharmacol, 27(4): 629-633.
Prostaglandin-Synthesis-Inhibitor	IC50=9.2 uM	Duke, 1992 *
Sedative	not available	Duke, 1992 *
Termiticide	LD100=5 mg/g	Duke, 1992 *
Trichomonicide	LD100=300 ug/ml	Duke, 1992 *
Trichomonistat	IC50=10 ug/ml	Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Trypsin-Enhancer	not available	Lawrence Review of Natural Products, Dec-93.
Ulcerogenic	not available	Phytotherapy Research, 4: 93.
Varroacide	not available	Duke, 1992 *
Vasodilator	not available	Duke, 1992 *
Vermifuge	not available	Duke, 1992 *

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List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name	Plant Part	Low Parts Per Million	High Parts Per Million	Standard Deviation	Reference
Morinda citrifolia	Fruit	not available	0.0	-0.7	Duke, 1992 *
Morus alba	Plant	not available	not available	not available	Duke, 1992 *
Myristica fragrans	Essential Oil	2000.0	3000.0	-0.7	Duke, 1992 *
Myristica fragrans	Seed Essent. Oil	1000.0	38000.0	not available	Duke, 1992 *
Myristica fragrans	Seed	40.0	320.0	-0.9	Duke, 1992 *
Myroxylon balsamum	Plant	not available	not available	not available	Duke, 1992 *
Myrtus communis	Shoot	1.0	15.0	-0.5	Duke, 1992 *
Narcissus tazetta	Flower	not available	not available	not available	Duke, 1992 *
Nicotiana tabacum	Leaf	not available	not available	not available	ANON. 1948-1976. The Wealth of India raw materials. Publications and Information Directorate, CSIR, New Delhi. 11 volumes.
Ocimum basilicum	Leaf Essent. Oil	51200.0	270000.0	-0.3	Duke, 1992 *
Ocimum basilicum	Leaf	14.0	8575.0	0.2	Duke, 1992 *
Ocimum basilicum	Plant	not available	14.0	-0.6	Duke, 1992 *
Ocimum basilicum	Essential Oil	300.0	857500.0	1.7	Duke, 1992 *
Ocimum basilicum	Shoot Essent. Oil	5700.0	26700.0	not available	Duke, 1992 *
Ocimum canum	Shoot	not available	not available	not available	=ICMR(Indian Council of Medical Research).1976.Medicinal Plants of India.Vol.1.Indian Council of Med. Res.Cambridge Printing Works, New Delhi.487 pp;ICMR.1987.Medicinal Plants of India.Vol.2.Indian Council of Med. Res.Cambr. Printing Works,New Delhi.600pp
Ocimum gratissimum	Plant	0.0	5340.0	2.3	Duke, 1992 *
Ocimum gratissimum	Seed	not available	1670.0	-0.5	ANON. 1948-1976. The Wealth of India raw materials. Publications and Information Directorate, CSIR, New Delhi. 11 volumes.
Ocimum gratissimum	Shoot	not available	4045.0	2.8	Vostrowsky, O., Garbe, W., Bestmann, H.J. and Maia, J.G.S. 1990. Essential Oil of Alfavaca, Ocimum gratissimum, from Brazilian Amazon. Zeitschr. Naturforschung 45(C): 1073-6.
Ocimum kilimandscharicum	Shoot	0.0	3000.0	1.9	Charles, D.J., and Simon, J.E. 1992. Essential Oil Constituents of Ocimum killimandscharicum Guerke. J. Ess. Oil Res., 4: 125-128.
Ocimum kilimandscharicum	Flower	0.0	35.0	-0.4	Charles, D.J., and Simon, J.E. 1992. Essential Oil Constituents of Ocimum killimandscharicum Guerke. J. Ess. Oil Res., 4: 125-128.