Chemical DEMECOLCINE | Dr. Duke's Phytochemical and Ethnobotanical Databases

Dr. Duke's Phytochemical and Ethnobotanical Databases

U.S. Department of Agriculture

Chemical ID

DEMECOLCINE

Ubiquitous

No

List of known dosages
Dosage
LDlo=6 (ivn rat)

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity	Dosage	Reference
Antileukemic	not available	Duke, 1992 *
Antimitotic	not available	Duke, 1992 *
Antipodagric	not available	Duke, 1992 *
Antitubulin	IC50=2.4 uM	Duke, 1992 *
Antitumor	not available	Merck 11th Edition
Marrow-Suppresant	not available	Martindale's 28th
MDR-Inhibitor	ED50=78 ng/ml	Tang-Wai, D. F., Brossi, A., Arnold, L. D., Gros, P. 1993. The Nitrogen of the Acetamido Group of Colchicine Modulates P-Glycoprotein-Mediated Multidrug Resistance. Biochemistry, 32(25): 6470-6476.

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List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name	Plant Part	Low Parts Per Million	High Parts Per Million	Standard Deviation	Reference
Colchicum autumnale	Plant	not available	not available	not available	Duke, 1992 *