Chemical CURCUMIN | Dr. Duke's Phytochemical and Ethnobotanical Databases

Dr. Duke's Phytochemical and Ethnobotanical Databases

U.S. Department of Agriculture

Chemical ID

CURCUMIN

Ubiquitous

No

List of known dosages
Dosage	Reference
LDlo=>2,000 mg/kg (orl mus)	Martindale's 28th
ADI=100 ug/kg	Martindale's 29th
TD=>5,000 mg/kg (orl rat)
LDlo=>1,800 mg/kg (orl rat)

Select a Results View:

Download these results as:

List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity	Dosage	Reference
Protease-Inhibitor	IC50=11-250 uM	Duke, 1992 *
Protein-Kinase-C-Inhibitor	IC69=15 uM	Duke, 1992 *
Protein-Kinase-C-Inhibitor	IC50=15 uM	Duke, 1992 *
Protein-Kinase-Inhibitor	not available	Duke, 1992 *
PTK-Inhibitor	5-100 uM	Duke, 1992 *
Pulmonoprotective	200 mg/kg/7 d	Duke, 1992 *
Quinone-Reductase-Inducer	3.4 uM	Singletary, K., et al. 1998. Effect of the Beta-Diketones Diferoloylmethane (Curcumin) and Dibenzoylmethane on Rat Mammary DNA Adducts and Tumors Induced by 7,12-dimethylbenz(A)anthracene. Carcinogenesis, 19(6): 1039-1043.
Radioprotective	not available	Duke, 1992 *
Sortase-A-Inhibitor	IC50=13-14 ug/ml	Duke, 1992 *
Sucrase-Promoter	not available	Duke, 1992 *
TNF-Inhibitor	not available	Duke, 1992 *
Topoisomerase-I-Inhibitor	not available	Duke, 1992 *
Topoisomerase-II-Inhibitor	not available	Duke, 1992 *
Ulcerogenic	orl rat	Duke, 1992 *
VEGF-Inhibitor	not available	Duke, 1992 *

Download these results as:

List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name	Plant Part	Low Parts Per Million	High Parts Per Million	Standard Deviation	Reference
Costus speciosus	Rhizome	not available	not available	not available	Duke, 1992 *
Curcuma longa	Root	not available	800.0	not available	Duke, 1992 *
Curcuma longa	Plant	not available	not available	not available	Duke, 1992 *
Curcuma longa	Resin, Exudate, Sap	not available	175000.0	not available	Duke, 1992 *
Curcuma longa	Rhizome	9.0	56000.0	1.4	Duke, 1992 *
Curcuma xanthorrhiza	Rhizome	100.0	10000.0	-0.5	Duke, 1992 *
Curcuma zedoaria	Rhizome	0.0	1000.0	-0.9	Duke, 1992 *
Zingiber officinale	Plant	not available	not available	not available	Stitt, Paul. Why George should eat broccoli.
Zingiber officinale	Rhizome	not available	not available	not available	Duke, 1992 *