Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture

Chemical COLCHICEINE

Chemical ID
COLCHICEINE
Ubiquitous
No
List of known dosages
Dosage
LD50=84 (ipr mus)
LDlo=0.043 (orl hmn)

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity Dosage Reference
MDR-Inhibitor ED50=15 ng/ml Tang-Wai, D. F., Brossi, A., Arnold, L. D., Gros, P. 1993. The Nitrogen of the Acetamido Group of Colchicine Modulates P-Glycoprotein-Mediated Multidrug Resistance. Biochemistry, 32(25): 6470-6476.