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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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  2. BROMELAIN

BROMELAIN

Chemical ID
BROMELAIN
Ubiquitous
No
List of known dosages
Dosage Reference
LD50=20-35 (ivn rbt) Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
LD50=36 (ipr mus)
LD50=>10,000 (orl rat)
LD50=20-35 (ivn mus) Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
LD50=30-35 (par mus) Commission E. Blumenthal,M.,Hall,T. and Rister,R.S. eds.1997.The ABC's German Commission E Monographs - Therapeutic Monographs on Medicinal Plants for Human Use by Commission E - A Special Expert Committee of the German Federal Health Agency.ABC.Austin TX
LD50=85.2 (ipr rat) Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
LD50=>20 (par rbt) Commission E. Blumenthal,M.,Hall,T. and Rister,R.S. eds.1997.The ABC's German Commission E Monographs - Therapeutic Monographs on Medicinal Plants for Human Use by Commission E - A Special Expert Committee of the German Federal Health Agency.ABC.Austin TX

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity Dosage Reference
Fibrinolytic EC50=25 mg/kg *
Hypotensive Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Laxative Martindale's 29th
Lipolytic *
Mucolytic *
Myorelaxant Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Nematicide *
Pesticide *
Proliferant IC40=3-6 uM *
Proliferant IC50=0.2 uM *
Prostaglandin-Synthetase-Inhibitor hmn *
Proteolytic 400-600 mg 3 x/day *
Vermifuge *
Vulnerary Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
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List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name Plant Part Low Parts Per Million High Parts Per Million Standard Deviation Reference
Ananas comosus Fruit 800.0 *
Ananas comosus Fruit Juice *
Ananas comosus Pericarp 750.0 *
Ananas comosus Stem 400.0 6000.0 *
Ananas comosus Leaf *