An official website of the United States government.
Chemical ID
18CINEOLE
Ubiquitous
No
| Dosage | Reference |
|---|---|
| LD50=2,480 (orl rat) | Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253. |
| LD50=3,480 mg/kg | |
| LD50=>5,000 (dml rbt) | |
| LD100=1,000 ug/ml | |
| LD50=100 mg/kg (ims mus) | Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin. |
| Activity | Dosage | Reference |
|---|---|---|
| Expectorant | not available | Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. |
| FLavor | FEMA 1-200 | Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry |
| Fungicide | not available | Duke, 1992 * |
| Gastroprotective | not available | Duke, 1992 * |
| Gram(+)icide | not available | Duke, 1992 * |
| Gram(-)icide | not available | Duke, 1992 * |
| Hepatotonic | not available | Duke, 1992 * |
| Herbicide | IC50=78 uM | Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp. |
| Hypotensive | not available | Duke, 1992 * |
| Inflammatory | inj | Duke, 1992 * |
| Insectifuge | not available | Duke, 1992 * |
| Irritant | not available | Rinzler, C. A. 1990. The Complete Book of Herbs, Spices and Condiments. Facts on File, New York. 199 pp. |
| Myorelaxant | not available | Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp. |
| Nematicide | not available | Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp. |
| Neurotoxic | not available | Duke, 1992 * |
| P450-Inducer | not available | Duke, 1992 * |
| Pediculicide | 2.3 x pyrethrin | Duke, 1992 * |
| Perfume | not available | Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry |
| Pesticide | not available | Duke, 1992 * |
| Rubefacient | not available | Martindale's 29th |
| Plant Name | Plant Part | Low Parts Per Million | High Parts Per Million | Standard Deviation | Reference |
|---|---|---|---|---|---|
| Turnera diffusa | Leaf | 550.0 | 1100.0 | -0.4 | List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979. |
| Umbellularia californica | Plant | 2340.0 | 9360.0 | 2.1 | Duke, 1992 * |
| Vaccinium corymbosum | Fruit | not available | not available | not available | Duke, 1992 * |
| Valeriana officinalis | Leaf | 85.0 | 1660.0 | -0.3 | Duke, 1992 * |
| Vetiveria zizanioides | Root | not available | 15.0 | not available | Duke, 1992 * |
| Vitex agnus-castus | Leaf | not available | 115.0 | -0.5 | Ekundayo, O., Laakso, I., Holopainen, M., Hiltunen, R., Oguntimein, B., and Kauppinen, V. 1990. The Chemical Composition and Antimicrobial Activity of the Leaf Oil of Vitex agnus-castus L. J. Essential Oil Research, 2: 115-119. |
| Vitex agnus-castus | Flower | not available | not available | not available | Duke, 1992 * |
| Vitex agnus-castus | Fruit | 600.0 | 4225.0 | -0.2 | Duke, 1992 * |
| Zea mays | Silk Stigma Style | not available | not available | not available | Duke, 1992 * |
| Zingiber officinale | Rhizome Essent. Oil | 26000.0 | 100000.0 | not available | Duke, 1992 * |
| Zingiber officinale | Rhizome | not available | 490.0 | -0.8 | Duke, 1992 * |