An official website of the United States government.
Chemical ID
18CINEOLE
Ubiquitous
No
| Dosage | Reference |
|---|---|
| LD50=2,480 (orl rat) | Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253. |
| LD50=3,480 mg/kg | |
| LD50=>5,000 (dml rbt) | |
| LD100=1,000 ug/ml | |
| LD50=100 mg/kg (ims mus) | Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin. |
| Activity | Dosage | Reference |
|---|---|---|
| Expectorant | not available | Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. |
| FLavor | FEMA 1-200 | Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry |
| Fungicide | not available | Duke, 1992 * |
| Gastroprotective | not available | Duke, 1992 * |
| Gram(+)icide | not available | Duke, 1992 * |
| Gram(-)icide | not available | Duke, 1992 * |
| Hepatotonic | not available | Duke, 1992 * |
| Herbicide | IC50=78 uM | Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp. |
| Hypotensive | not available | Duke, 1992 * |
| Inflammatory | inj | Duke, 1992 * |
| Insectifuge | not available | Duke, 1992 * |
| Irritant | not available | Rinzler, C. A. 1990. The Complete Book of Herbs, Spices and Condiments. Facts on File, New York. 199 pp. |
| Myorelaxant | not available | Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp. |
| Nematicide | not available | Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp. |
| Neurotoxic | not available | Duke, 1992 * |
| P450-Inducer | not available | Duke, 1992 * |
| Pediculicide | 2.3 x pyrethrin | Duke, 1992 * |
| Perfume | not available | Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry |
| Pesticide | not available | Duke, 1992 * |
| Rubefacient | not available | Martindale's 29th |
| Plant Name | Plant Part | Low Parts Per Million | High Parts Per Million | Standard Deviation | Reference |
|---|---|---|---|---|---|
| Pycnanthemum incanum | Shoot | 33.0 | 76.0 | -0.1 | Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980. |
| Pycnanthemum loomisii | Shoot | 17853.0 | 26040.0 | 0.2 | Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980. |
| Pycnanthemum montanum | Shoot | 21.0 | 720.0 | -0.1 | Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980. |
| Pycnanthemum muticum | Shoot | 1.0 | 50.0 | -0.1 | Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980. |
| Pycnanthemum pilosum | Flower | 10.0 | 35.0 | -0.4 | Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980. |
| Pycnanthemum pilosum | Leaf | 10.0 | 35.0 | -0.5 | Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980. |
| Pycnanthemum pycnanthemoides | Shoot | 39.0 | 116.0 | -0.1 | Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980. |
| Pycnanthemum setosum | Shoot | 20.0 | 7099.0 | 0.0 | Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980. |
| Pycnanthemum tenuifolium | Shoot | 1.0 | 1100.0 | -0.1 | Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980. |
| Pycnanthemum torreyi | Shoot | not available | 10.0 | -0.1 | Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980. |
| Pycnanthemum verticillatum | Shoot | not available | 42.0 | -0.1 | Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980. |
| Pycnanthemum virginianum | Shoot | 6.0 | 58.0 | -0.1 | Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980. |
| Ravensara aromatica | Bark | not available | 44.0 | -1.0 | Duke, 1992 * |
| Ravensara aromatica | Leaf | not available | 20.0 | -0.5 | Duke, 1992 * |
| Ribes nigrum | Fruit | not available | not available | not available | List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979. |
| Rosmarinus eriocalyx | Shoot | 380.0 | 705.0 | -0.1 | Soriano Cano, M.C., Sotomayor Sanchez, J.A., Sanchez Gomez, P. and Garcia Vallejo, M.C. 1993. Essential Oils of the Rosmarinus eriocalyx-tomentosus Complex in Southeast Spain. J. Ess. Oil Res. 5: 243-246. |
| Rosmarinus eriocalyx | Shoot | 380.0 | 705.0 | -0.1 | Soriano Cano, M.C., Sotomayor Sanchez, J.A., Sanchez Gomez, P. and Garcia Vallejo, M.C. 1993. Essential Oils of the Rosmarinus eriocalyx-tomentosus Complex in Southeast Spain. J. Ess. Oil Res. 5: 243-246. |
| Rosmarinus officinalis | Leaf | not available | 0.0 | -0.5 | Soliman, F.M., El-Kashoury, M.M., Fathy, M.M. and Gonaid, M.H. 1994. Analysis and Biological Activity of the Essential Oil of Rosmarinus officinalis L. from Egypt. Flavour and Fragrance J. 9: 29-33. |
| Rosmarinus officinalis | Leaf | not available | 0.0 | -0.5 | Soliman, F.M., El-Kashoury, M.M., Fathy, M.M. and Gonaid, M.H. 1994. Analysis and Biological Activity of the Essential Oil of Rosmarinus officinalis L. from Egypt. Flavour and Fragrance J. 9: 29-33. |
| Rosmarinus officinalis | Plant | 0.0 | 8125.0 | 1.7 | Duke, 1992 * |