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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Cytotoxic

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
16-ACETYLSTROSPESIDE 0.035 ug/ml Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
19-O-METHYLANGUSTOLINE ED50=2.32 ug/ml *
2'',3''-DIHYDROROBUSTAFLAVONE-7,4'-DIMETHYL-ETHER Lin, L., Kuo, Y., Chou, C. 2000. Cytotoxic Biflavonoids from Selaginella delicatula. J. Natural Products, 63(5): 627-630.
2'-ACETYLNERIIFOLIN 9KB ED50=0.033 ppm Alkofahi, A., Rupprect, J. K., Anderson, J. E., McLaughlin, J. L., Mikolajczak, K. L., and Scott, B. A., Search for new pesticides from higer plants, Chap. 3 in ???, Arnason et al, eds, ACS, Washington, 1989
2,5-DIMETHOXY-P-BENZOQUINONE ED50=1.3-5.2ug/ml *
2-ALPHA-HYDROXYALANTOLACTONE *
2-HYDROXY-METHYL-ANTHRAQUINONE Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
2-N-NOROBAMEGINE ED50=2.3 Collins, D.J., Culvenor, C.C.J., Lamberton, J.A., Loder, J.W. and Price, J.R., Plants for Medicines, CSIRO, East Melbourne, Australia, 1990, 303 pp.
22-HYDROXYTINGENONE ED50=0.07-0.84 ug/ml *
28,29-DIHYDROXYFRIEDELAN-3-ONE ED50=0.64 ug/ml *
3,3',4-TRI-O-METHYL-ELLAGIC-ACID ED50(KB)=7.7 ug/ml *
3,5-DIHYDROXY-4-METHOXYBENZOIC-ACID-METHYL-ESTER ED50=8.6 ug/ml Arisawa, M., Hayashi, T., Shimizu, M., Morita, N., Bai, H., Kuze, S., and Ito, Y. Isolation And Cytotoxicity Of Two New Flavonoids From Chrysosplenium grayanum And Related Flavonols. J. Natural Products, 54(3): 898-901, 1991.
3-(3,3-DIMETHYLALLYL)-5-(3-ACETYL-2,4-DIHYDROXY-5-METHYL-6-METHOXYBENZYL)-PHLORACETOPHENONE *
3-ACETOXYNORERYTHROSTACHAMINE ED50=490 ug/ml Collins, D.J., Culvenor, C.C.J., Lamberton, J.A., Loder, J.W. and Price, J.R., Plants for Medicines, CSIRO, East Melbourne, Australia, 1990, 303 pp.
3-ACETOXYNORERYTHROSUAMINE ED50=300 ug/ml Collins, D.J., Culvenor, C.C.J., Lamberton, J.A., Loder, J.W. and Price, J.R., Plants for Medicines, CSIRO, East Melbourne, Australia, 1990, 303 pp.
3-ALPHA,17-ALPHA-CINCHOPHYLLINE IC50=3.55 ug/ml Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
3-ALPHA,17-BETA-CINCHOPHYLLINE IC50=0.4 ug/ml Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
3-BETA,17-BETA-CINCHOPHYLLINE IC50=2.24 ug/ml Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
3-BETA-23,28-TRIHYDROXY-12-OLEANENE-23-CAFFEATE *
3-BETA-23,28-TRIHYDROXY-12-OLEANENE-3-BETA-CAFFEATE *
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List of Activity Plants.
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Plant Name Common Name Chemical Count Total Parts Per Million
Senna alexandrina Alexandran senna; True Senna; Indian Senna 2 0
Senna lindheimeriana 1 100.80000305175781
Senna obtusifolia Sicklepod 2 1, 800
Senna occidentalis Coffee Senna 6 2, 500
Serenoa repens Saw Palmetto; Scrub-Palmetto 4 0
Sesamum indicum Sesame; Benneseed; Beni; Ajonjoli (Sp.); Sesamo (Sp.) 5 1, 940
Shorea affinis 2 1, 820
Shorea congestiflora 2 0
Shorea dyerii 2 900
Shorea magistophylla 2 60
Shorea oblongifolia 2 0
Shorea ovalifolia 2 0
Shorea stipularvis 2 1, 460
Shorea trapezifolia 2 0
Shorea zeylanica 2 0
Silybum marianum Milk Thistle; Lady's Thistle 5 0
Simaba multiflora Cajurana 1 0
Simaba obovata 1 0
Skimmia arborescens Skimmia 4 0
Solanum aviculare 1 60, 000