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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Antimalarial

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
ANCISTROBERTSONINE-D IC50=4.8 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ANCISTROBREVINE IC50=5-25 ug/ml *
ANCISTROBREVINE-B IC50=2-4.7 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ANCISTROCLADINE IC50=5-25 ug/ml *
ANCISTROHEYNINE-A IC50=2.1 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ANCISTROLIKOKINE-A IC50=0.14-0.19 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ANCISTROLIKOKINE-B IC50=0.21-0.54 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ANCISTROLIKOKINE-C IC50=0.62-0.92 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ANHYDROLYCORINE IC50=6.1-6.4 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ANNONACIN IC50=1.3-1.5 ppm Rupprect, J. K., Hui, Y. H., and McLaughlin, J. L., Annonaceous acetogenins: a review, J. Nat. Prod, 53(2), 1990, 237-238.
ANOLIGNAN IC50=20 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
APIOLE *
ARBORININE IC50=8.5 ug/ml Khalid, S.A., Farouk, A., Geary**, T.G., and Jensen, J.B. 1985. Potential Antimalarial Candidates From African Plants: An In Vitro Approach Using Plasmodium falciparum*. Journal of Ethnopharmacology, 15: 201-209, 1986.
AROMOLINE IC50=0.67 ug/ml (ca 1/5 chloroquine) *
ARTARINE *
ARTEANNUIN *
ARTEINCULTON IC50=7.5 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ARTEMETHER Merck 11th Edition
ARTEMETIN (Synergic w artemisinin) IC50=26 uM *
ARTEMISINE *
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Gypsophila struthium 1 9.600000381469727
Haematoxylum campechianum Campechy; Logwood 1 0
Hamamelis virginiana Witch Hazel 1 0
Harpagophytum procumbens Devil's Claw; Grapple Plant 2 0
Hedera helix Ivy 3 0
Heimia salicifolia Sinicuichi 1 0
Helianthus annuus Sunflower; Girasol 5 1, 240
Helichrysum angustifolium Everlasting; Immortelle 1 0
Hemidesmus indicus Indian Sarsaparilla 2 0
Herpestis monniera 1 1, 100
Hibiscus mutabilis 1 0
Hibiscus rosa-sinensis Chinese hibiscus; Shoe-flower 1 0
Hippeastrum vittatum Barbados lily 1 0
Hippophae rhamnoides Sallow Thorn; Sea Buckthorn; Yellow Spine 1 0
Hoffmannia strigillosa 1 12.5
Holarrhena pubescens Tellicherry Bark; Zhi Xie Mu; Conessi; Kurchi 3 0
Hopea brevipetiolaris 1 0
Hopea cordifolia 1 360
Hopea jucunda 1 160
Houttuynia cordata Fishwort; Dokudami; Yu Xing Cao 3 3, 600