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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Antimalarial

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
SECURININE 5.4 ug/ml *
SERGEOLIDE ED50=0.26 mg/kg day Grenand, P., Moretti, C., and Jacquemin, H. 1987. Pharmacopees Traditionnelles en Guyane. l'ORSTROM, Paris. 569 pp.
SIMALIKALACTONE-D IC50=0.001-0.002 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
SIPANDINOLIDE IC50=46 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
SKIMMIANINE IC50=48.2 ug/ml Khalid, S.A., Farouk, A., Geary**, T.G., and Jensen, J.B. 1985. Potential Antimalarial Candidates From African Plants: An In Vitro Approach Using Plasmodium falciparum*. Journal of Ethnopharmacology, 15: 201-209, 1986.
SUNGUCINE IC50=7.8-10.1 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
SWERCHIN Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
TALCARPINE IC50=40.3 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
TERMILIGNAN IC50=6-9 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
THALIFABERIDINE IC50=0.12-0.88 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
THALIFABERINE IC50=0.44-5.1 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
THALIFASINE IC50=0.05-0.24 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
TILIACORINE IC50=0.67 ug/ml *
TILIACORININE IC50=3.5 ug/ml *
TOMENTOSRIN IC50=7.8 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
TOTAQUINE 600 mg/3x/day/man Martindale's 29th
TRANS-PINOCARVEOL IC50=5-50 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
TRANS-PINOCARVYL-HYDROPEROXIDE IC50=7.5 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
TRICHIRUBRINE-A IC50=0.3 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
TRIGILLETIMINE IC50=22 ug/ml (ca 1/200 x chloroquine) *
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Citrus sinensis Orange 5 15, 103.400000095367
Citrus spp Citrus 2 0
Claoxylon polot 1 10
Clinopodium umbrosum 1 0
Clusia arboricida 1 60.79999923706055
Clusia sp. 1 0
Cnicus benedictus Blessed Thistle 3 0
Coccinia grandis Ivy Gourd; Kundree; Tindora; Tindori; Pepasan; Little Gourd; Kanduri 1 0
Coccoloba excoriata 1 0
Colchicum autumnale Autumn Crocus; Meadow Saffron 1 24, 600
Coleus barbatus Forskohl's Coleus 1 17, 000
Colubrina granulosa 1 0
Combretum imberbe 1 0
Commiphora wightii Guggul; Indian Bdellium-Tree 2 0
Consolida ajacis Larkspur 1 0
Convallaria majalis Lily-Of-The-Valley 1 0
Copaifera spp Copaiba 3 0
Coptis chinensis Chinese Goldthread; Huang-Lian; Huang-Lien 3 540, 000
Coptis japonica Huang-Lia; Huang-Lian; Huang-Lien; Japanese Goldthread 3 560, 000
Coptis spp Generic Goldthread 4 180, 000