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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Antimalarial

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
QUERCETIN IC50=1-6.4 ug/ml Medicinal and Poisonous Plants of the Tropics. Leeuwenberg, A.J.M., ed. Pudoc, Wageningen. 1987.
QUINDOLINE IC50=>229 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
QUINICINE IC50=11.2 ug/ml Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
QUINIDINE 10 mg/kg/orl/man/8 hrs Martindale's 29th
QUINIDINONE IC50=4.7 ug/ml Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
QUININE IC50=0.18 ug/ml Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
QUININE-SULFATE 2,000 mg/man/day Martindale's 28th
QUINOLINE Merck 11th Edition
ROBUSTANOL *
ROEMREFRIDINE IC50=0.6-0.7 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
RUBIADIN-1-METHYL-ETHER IC50=8-83 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
RUGOSAL-A IC50=1 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
RUTIN IC50=>100 ug/ml Khalid, S.A., Farouk, A., Geary**, T.G., and Jensen, J.B. 1985. Potential Antimalarial Candidates From African Plants: An In Vitro Approach Using Plasmodium falciparum*. Journal of Ethnopharmacology, 15: 201-209, 1986.
SALANNIN IC50=50 ug/ml *
SAMADERINE-B-CHAPARRINONE IC50=0.071 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
SAMADERINE-E-CHAPARRINONE IC50=0.021 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
SAMADERINE-X-CHAPARRINONE IC50=0.015 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
SAMADERINE-Z-CHAPARRINONE IC50=0.071 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
SARACHINE IC50=0.01-0.07 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
SECURINE IC50=5.4 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Myristica fragrans Mace; Nutmeg; Muskatnussbaum (Ger.); nogal moscado (Sp.); nuez moscada (Sp.) 2 0
Myroxylon balsamum Peru Balsam; Tolu Balsam 1 0
Myrrhis odorata Garden Myrrh; Myrrh; Sweet Chervil; Sweet Cicely; Cicely 1 47, 500
Myrtus communis Myrtle; Myrte (Ger.); Arrayan (Sp.); Mirto (Sp.) 5 1, 048
Nandina domestica Heavenly Bamboo; Sacred Bamboo; Southern Heaven Bamboo; Nanten (Jap.) 2 0
Narcissus tazetta Daffodil 1 0
Nasturtium officinale Berro; Watercress 1 0
Nelumbo nucifera Water Lotus 2 0
Nepeta cataria Catnip 1 10, 300
Nepeta racemosa Catmint 3 164
Nerium oleander Oleander 5 43, 000
Neurolaena lobata Bitter Wood; Contragavilana 2 0
Newcastelia viscida 1 0
Nicotiana glauca Tree Tobacco 1 21, 000
Nicotiana tabacum Tobacco 2 10, 000
Nigella sativa Black Cumin; Roman Coriander; Fennel-Flower; Nutmeg-Flower; Black Caraway 1 1, 000
Nuytsia floribunda 1 17, 000
Nymphoides peltatum 1 0
Ocimum americanum 1 0
Ocimum basilicum Basil; Sweet Basil; Cuban Basil 7 16, 944