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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Antimalarial

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
(-)-CORYDALMINE IC50=840-2840 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(-)-CURINE IC50=353 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(-)-CYCLEAPELTINE IC50=0.03-0.04 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(-)-DICENTRINE IC50=1260-2550 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(-)-ISOLAURELINE IC50=1610-2560 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(-)-NOR-DICENTRINE IC50=470-1030 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(-)-ROEMEROLINE IC50=1,780-3,150 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(-)-TETRAHYDROSTEPHABINE IC50=1,940-2,230 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(-)-THAICANINE IC50=550-1,610 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(-)-XYLOPINE IC50=440-2,270 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(8',9'-DIHYDROXY)-3-FARNESYLINDOLE IC50=2.8 ug/ml *
1(S)-HYDROXY-ALPHA-BISABOLOLOXIDE IC50=5.09 ug/ml *
1,2-DI-O-ACETYLCORINE IC50=1 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
1-BETA-HYDROPEROXYISOBILIN IC50=1 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
1-DEACETYLKHIVORIN IC50=10 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
1-HYDROXYBENZOISOCHROMAN IC50=2.7 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
1-O-ACETYLNORPLUVIININE IC50=28.3-34.2 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
10'-HYDROXYUSAMBARENSINE IC50=0.2-0.5 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
10,12-PEROXYCALAMENENE IC50=2.3 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
11-BETA-ACETOXYGEDUNIN IC50=3.11 ug/ml *
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Arbutus unedo Arbutus; Strawberry Tree 5 0
Arctium lappa Gobo; Great Burdock; Burdock 2 0
Arctostaphylos uva-ursi Bearberry; Uva Ursi 7 25, 909
Ardisia japonica Marlberry 1 0
Argemone mexicana Prickly Poppy 1 820
Armoracia rusticana Horseradish 1 0
Artemisia abrotanum Southernwood 2 0
Artemisia absinthium Wormwood 2 60
Artemisia annua Qinghao; Sweet Annie; Annual Mugwort (GRIN); Annual Wormwood (GRIN); Sweet Wormwood (GRIN) 15 309, 175
Artemisia capillaris Capillary Wormwood 1 0
Artemisia dracunculus Tarragon 4 560
Artemisia herba-alba Desert Wormwood 3 0
Artemisia indica 4 155
Artemisia salsoloides 3 10, 150
Artemisia vulgaris Mugwort 1 0
Artocarpus altilis Breadfruit 1 0
Artocarpus heterophyllus Jackfruit 2 0
Artocarpus integrifolia 1 3, 000
Arundo donax Giant Reed 1 0
Asimina triloba Pawpaw 2 0