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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture

Biological Activity Antimalarial

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
(-)-CORYDALMINE IC50=840-2840 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(-)-CURINE IC50=353 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(-)-CYCLEAPELTINE IC50=0.03-0.04 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(-)-DICENTRINE IC50=1260-2550 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(-)-ISOLAURELINE IC50=1610-2560 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(-)-NOR-DICENTRINE IC50=470-1030 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(-)-ROEMEROLINE IC50=1,780-3,150 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(-)-TETRAHYDROSTEPHABINE IC50=1,940-2,230 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(-)-THAICANINE IC50=550-1,610 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(-)-XYLOPINE IC50=440-2,270 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
(8',9'-DIHYDROXY)-3-FARNESYLINDOLE IC50=2.8 ug/ml *
1(S)-HYDROXY-ALPHA-BISABOLOLOXIDE IC50=5.09 ug/ml *
1,2-DI-O-ACETYLCORINE IC50=1 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
1-BETA-HYDROPEROXYISOBILIN IC50=1 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
1-DEACETYLKHIVORIN IC50=10 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
1-HYDROXYBENZOISOCHROMAN IC50=2.7 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
1-O-ACETYLNORPLUVIININE IC50=28.3-34.2 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
10'-HYDROXYUSAMBARENSINE IC50=0.2-0.5 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
10,12-PEROXYCALAMENENE IC50=2.3 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
11-BETA-ACETOXYGEDUNIN IC50=3.11 ug/ml *
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Polygonum hydropiper Common Smartweed 3 30, 000
Polygonum hydropiperoides Mild Water Pepper 1 0
Polygonum multiflorum Chinese Cornbind; Fleeceflower; Fo Ti; He Shou Wu; Chinese Knotweed 1 0
Polygonum plebeium 1 75
Pongamia pinnata 1 45
Populus balsamifera Balsam Poplar 1 0
Populus tacamahacca Balm Of Gilead 2 0
Pouteria torta 1 15
Prosopis glandulosa Mesquite; Honey Mesquite 2 320
Prosopis juliflora Mesquite 1 0
Prunella vulgaris Self-Heal; Heal-All 6 10, 281.760000228882
Prunus africana Bitter Almond; Red Stinkwood 2 57, 800
Prunus armeniaca Apricot 2 17, 700
Prunus cerasus Sour Cherry 4 0
Prunus domestica Plum 1 0
Prunus dulcis Almond 1 0
Prunus laurocerasus Cherry Laurel 2 10, 000
Prunus persica Peach 2 0
Prunus serotina Black Cherry; Wild Cherry 2 0
Prunus spinosa Blackthorn; Sloe 2 0