Porophyllum ruderale | Plant | Dr. Duke's Phytochemical and Ethnobotanical Databases

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Common name(s)

Quilquinya

How used

Medicinal

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Activities: 90

Chemicals w/Activities: 13

All Chemicals: 25

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# Activity	Chemical Name	Part	Low PPM	High PPM	StdDev	^*Reference
0	(E)-ANETHOLE	Plant	6.0	9.0	--	Loayza, I., de Groot, W., Lorenzo, D. et al. 1999. Composition of the essential oil of Porophyllum ruderale (Jacq.) Cass. from Bolivia. Flav. & Fragr. J. 14: 393-8.
0	(E)-BETA-OCIMENE	Plant	3.0	4.0	-0.61	Loayza, I., de Groot, W., Lorenzo, D. et al. 1999. Composition of the essential oil of Porophyllum ruderale (Jacq.) Cass. from Bolivia. Flav. & Fragr. J. 14: 393-8.
0	(E)-CARYOPHYLLENE	Plant	15.0	22.0	--	Loayza, I., de Groot, W., Lorenzo, D. et al. 1999. Composition of the essential oil of Porophyllum ruderale (Jacq.) Cass. from Bolivia. Flav. & Fragr. J. 14: 393-8.
0	(E)-NEROLIDIOL	Plant	3.0	4.0	--	Loayza, I., de Groot, W., Lorenzo, D. et al. 1999. Composition of the essential oil of Porophyllum ruderale (Jacq.) Cass. from Bolivia. Flav. & Fragr. J. 14: 393-8.
0	(Z)-BETA-OCIMENE	Plant	80.0	120.0	1.41	Loayza, I., de Groot, W., Lorenzo, D. et al. 1999. Composition of the essential oil of Porophyllum ruderale (Jacq.) Cass. from Bolivia. Flav. & Fragr. J. 14: 393-8.
8	4-TERPINEOL	Plant	310.0	465.0	-1.00	Loayza, I., de Groot, W., Lorenzo, D. et al. 1999. Composition of the essential oil of Porophyllum ruderale (Jacq.) Cass. from Bolivia. Flav. & Fragr. J. 14: 393-8.
Antiasthmatic * Antioxidant * Antiradicular * Diuretic Rinzler, C. A. 1990. The Complete Book of Herbs, Spices and Condiments. Facts on File, New York. 199 pp. FLavor FEMA 20-100 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Insectifuge Bowers, W.S., Ortego, F., You, X., and Evans, P.H. Insect Repellents From The Chinese Prickly Ash Zanthoxylum bungeanum. Journal of Natural Products, 56(6): 935-938, 1993. Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Pesticide *
11	ALPHA-PHELLANDRENE	Plant	3.0	4.0	-1.14	Loayza, I., de Groot, W., Lorenzo, D. et al. 1999. Composition of the essential oil of Porophyllum ruderale (Jacq.) Cass. from Bolivia. Flav. & Fragr. J. 14: 393-8.
Antibacterial Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands. Antistaphylococcic Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands. Dermal Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Emetic * FLavor FEMA 10-130 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Fungicide Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin. Insectiphile Pakistan Encyclopedia Planta Medica. 1986. Irritant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Laxative * Perfumery Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Pesticide *
28	ALPHA-PINENE	Plant	27.0	40.0	-0.45	Loayza, I., de Groot, W., Lorenzo, D. et al. 1999. Composition of the essential oil of Porophyllum ruderale (Jacq.) Cass. from Bolivia. Flav. & Fragr. J. 14: 393-8.
Allelochemic * Allergenic * Antiacne * Antibacterial * Antifeedant * Antiflu Economic & Medicinal Plant Research, 5: 195. Antiinflammatory 500 mg/kg * Antipneumonic * Antiseptic * Antispasmodic * Antistaphylococcic * Antiviral Economic & Medicinal Plant Research, 5: 195. Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Coleoptophile * Expectorant Michael Castleman 1991. The Healing Herbs. Rodale Press, Emmaus, PA 436 pp. FLavor FEMA 15-150 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Herbicide IC50=30 uM Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp. Insecticide 0.82 uM/fly * Insectifuge 50 ppm * Insectiphile J. Stored. Prod. Res., 22:141, 1986. Irritant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. P450-2B1-Inhibitor IC50=0.087 uM * Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Pesticide * Sedative Lawrence Review of Natural Products, Jun-90. Spasmogenic * Tranquilizer Lawrence Review of Natural Products, Jun-90. Transdermal *
13	ALPHA-TERPINENE	Plant	55.0	85.0	-0.37	Loayza, I., de Groot, W., Lorenzo, D. et al. 1999. Composition of the essential oil of Porophyllum ruderale (Jacq.) Cass. from Bolivia. Flav. & Fragr. J. 14: 393-8.
Acaricide * ACE-Inhibitor 100 ug/ml (weak activity) * Aldose-Reductase-Inhibitor 100 ug/ml Okamura, K., Iwakami, S., Matsunaga, T. 1992. Biological Activity of Monoterpenes from Trees. Toyama-Ken Yakuji Kenkyusho Nenpo, (20): 95-101. Antiacetylcholinesterase IC50=1.0 mM * Antinitrosaminic * Antispasmodic * FLavor FEMA 1-40 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Insecticide 0.86 uM/fly * Insectifuge * P450-2B1-Inhibitor IC50=0.76 uM * Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Pesticide * Spasmogenic *
0	ALPHA-TERPINOLENE	Plant	24.0	36.0	1.00	Loayza, I., de Groot, W., Lorenzo, D. et al. 1999. Composition of the essential oil of Porophyllum ruderale (Jacq.) Cass. from Bolivia. Flav. & Fragr. J. 14: 393-8.
0	ALPHA-THUJENE	Plant	--	15.0	-0.56	Loayza, I., de Groot, W., Lorenzo, D. et al. 1999. Composition of the essential oil of Porophyllum ruderale (Jacq.) Cass. from Bolivia. Flav. & Fragr. J. 14: 393-8.
13	BETA-PINENE	Plant	3.0	4.0	-0.43	Loayza, I., de Groot, W., Lorenzo, D. et al. 1999. Composition of the essential oil of Porophyllum ruderale (Jacq.) Cass. from Bolivia. Flav. & Fragr. J. 14: 393-8.
Allergenic * Antiinflammatory * Antiseptic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. Antispasmodic * Candidicide * FLavor FEMA 15-600 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Herbicide Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp. Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253. Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Pesticide * Spasmogenic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp. Transdermal *
0	CIS-PINENE-HYDRATE	Plant	12.0	18.0	--	Loayza, I., de Groot, W., Lorenzo, D. et al. 1999. Composition of the essential oil of Porophyllum ruderale (Jacq.) Cass. from Bolivia. Flav. & Fragr. J. 14: 393-8.
2	DECANOL	Plant	3.0	4.0	1.40	Loayza, I., de Groot, W., Lorenzo, D. et al. 1999. Composition of the essential oil of Porophyllum ruderale (Jacq.) Cass. from Bolivia. Flav. & Fragr. J. 14: 393-8.
Nematicide MLC 100-700 ug/ml Shoyakugaku Zasshi, 44: 183. Pesticide *
0	EO	Plant	3000.0	4500.0	-0.40	Loayza, I., de Groot, W., Lorenzo, D. et al. 1999. Composition of the essential oil of Porophyllum ruderale (Jacq.) Cass. from Bolivia. Flav. & Fragr. J. 14: 393-8.
11	GAMMA-TERPINENE	Plant	100.0	155.0	-0.47	Loayza, I., de Groot, W., Lorenzo, D. et al. 1999. Composition of the essential oil of Porophyllum ruderale (Jacq.) Cass. from Bolivia. Flav. & Fragr. J. 14: 393-8.
Acaricide * ACE-Inhibitor 100 ug/ml (weak activity) * Aldose-Reductase-Inhibitor 100 ug/ml Okamura, K., Iwakami, S., Matsunaga, T. 1992. Biological Activity of Monoterpenes from Trees. Toyama-Ken Yakuji Kenkyusho Nenpo, (20): 95-101. Antiacetylcholinesterase IC23=1.2 mM * Antifeedant Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin. Antioxidant Jim Duke's personal files. FLavor FEMA 1-40 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Insectifuge Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin. Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253. Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Pesticide *
2	GERMACRENE-D	Plant	--	--	--	Loayza, I., de Groot, W., Lorenzo, D. et al. 1999. Composition of the essential oil of Porophyllum ruderale (Jacq.) Cass. from Bolivia. Flav. & Fragr. J. 14: 393-8.
Pesticide * Pheromone *
60	LIMONENE	Plant	9.0	13.0	-0.48	Loayza, I., de Groot, W., Lorenzo, D. et al. 1999. Composition of the essential oil of Porophyllum ruderale (Jacq.) Cass. from Bolivia. Flav. & Fragr. J. 14: 393-8.
Acaricide LC100=8 uM * AChE-Inhibitor Grundy, D. L. and Still, C. C., Inhibition of acetylcholinesterases by pulegone-1,2-epoxide, Oest. Biochem. & Physiol., 23, 1985, 383-8. Allelochemic * Allergenic 1/20th carene * Antiacetylcholinesterase IC22-26=1.2 mM * Antiadenomic * Antialzheimeran? Grundy, D. L. and Still, C. C., Inhibition of acetylcholinesterases by pulegone-1,2-epoxide, Oest. Biochem. & Physiol., 23, 1985, 383-8. Antiasthmatic * Antibacterial Revista Itiliana Eppos, 12: 5, 1994. Anticancer * Antiesophagitic * Antifeedant * Antiflu Economic & Medicinal Plant Research, 5: 195. Antiinflammatory * Antilithic * Antilymphomic * Antimetastatic (Stomach) * Antimutagenic Economic & Medicinal Plant Research, 6: 235. Antiobesity * Antiseptic * Antispasmodic ED50=0.197 mg/ml Fitoterapia No.59-1984. Antitumor * Antitumor (Breast) * Antitumor (Colon) * Antitumor (Pancreas) * Antitumor (Prostate) * Antitumor (Stomach) * Antiviral * Apoptotic * Bronchoprotectant * Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Candidistat * Chemopreventive * Cholesterolytic * Detoxicant * Enterocontractant J. Aromatherapy 4: 22. Expectorant * FLavor * Fungiphilic J. Agric. Food Chem. 43: 2283. Fungistat * GST-Inducer * Herbicide IC50=45 uM Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp. Histaminic * Immunomodulator * Insecticide 0.37 uM/fly * Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Interleukin-6-Inhibitor * Irritant * Lipolytic * Myorelaxant 50 mg/kg * Nematicide IC=100 ug/ml Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp. NO-Genic * Ornithine-Decarboxylase-Inhibitor ~750 mg/kg (diet) * Ozone-Scavenger * P450-Inducer * Peristaltic * Pesticide * Photosensitizer Rinzler, C. A. 1990. The Complete Book of Herbs, Spices and Condiments. Facts on File, New York. 199 pp. Sedative ED=1-32 mg/kg Wagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176) Transdermal *
22	MYRCENE	Plant	35.0	55.0	-0.42	Loayza, I., de Groot, W., Lorenzo, D. et al. 1999. Composition of the essential oil of Porophyllum ruderale (Jacq.) Cass. from Bolivia. Flav. & Fragr. J. 14: 393-8.
ACE-Inhibitor 100 ug/ml * Aldose-Reductase-Inhibitor 100 ug/ml Okamura, K., Iwakami, S., Matsunaga, T. 1992. Biological Activity of Monoterpenes from Trees. Toyama-Ken Yakuji Kenkyusho Nenpo, (20): 95-101. Allergenic * Analgesic Kauderer, B., Zamith, H., Paumgartten, F.J.R., and Speit, G. Evaluation of the Mutagenicity of B-Myrcene in Mammalian Cells In Vitro. Environmental and Molecular Mutagenesis 18: 28-34, 1991. Antibacterial * Anticonvulsant * Antimutagenic Kauderer, B., Zamith, H., Paumgartten, F.J.R., and Speit, G. Evaluation of the Mutagenicity of B-Myrcene in Mammalian Cells In Vitro. Environmental and Molecular Mutagenesis 18: 28-34, 1991. Antinitrosaminic * Antinociceptive 10-20 mg/kg ipr mus Rao, V.S.N., Menezes, A.M.S., Viana, G.S.B. 1990. Effect of myrcene on nociception in mice. J. Pharm. Pharmacol. 42: 877-878, 1990. Antinociceptive 20-40 mg/kg scu mus Rao, V.S.N., Menezes, A.M.S., Viana, G.S.B. 1990. Effect of myrcene on nociception in mice. J. Pharm. Pharmacol. 42: 877-878, 1990. Antioxidant Jim Duke's personal files. Antispasmodic Jim Duke's personal files. Chemopreventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. FLavor FEMA 0.5-9 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Fungicide Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp. Hypothermic * Insectifuge * Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253. Myorelaxant 100-200 mg/kg * P450-2B1-Inhibitor IC50=0.14 uM * Perfumery Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Pesticide *
1	N-DECANAL	Plant	38.0	55.0	--	Loayza, I., de Groot, W., Lorenzo, D. et al. 1999. Composition of the essential oil of Porophyllum ruderale (Jacq.) Cass. from Bolivia. Flav. & Fragr. J. 14: 393-8.
FLavor FEMA <1-4 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry

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^*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.

Plant Porophyllum ruderale (Asteraceae)

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