Rubus phoenicolasius | Plant | Dr. Duke's Phytochemical and Ethnobotanical Databases

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Common name(s)

Japanese Wineberry, Wine Raspberry, Wineberry

How used

Medicinal

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Activities: 83

Chemicals w/Activities: 9

All Chemicals: 18

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# Activity	Chemical Name	Part Filter by plant part	Low PPM	High PPM	StdDev	^*Reference
0	CARYATIN	Flower	--	--	--	Wollenweber, E., Dorr, M., Armbruster, S. 1993. Flavonoid Aglycones from Rosa centifolia cv. muscosa and Rubus phoenicolasius. Z Naturforsch Ser C, 48(11/12): 956-958.
0	CARYATIN	Inflorescence	--	--	--	Wollenweber, E., Dorr, M., Armbruster, S. 1993. Flavonoid Aglycones as Glandular Products in Rosa centifolia cv. muscosa and in Rubus phoenicolasius. Z Naturforsch Ser C, 48(11/12): 956-958.
4	CASUARININ	Leaf	--	--	--	Okuda, T., Yoshida, T., Hatano, T., Iwasaki, M., Kubo, M., Orime, T., Yoshizaki, M., Naruhashi, N. 1992. Hydrolysable Tannins as Chemotaxonomic Markers in the Rosaceae. Phytochemistry, 31(9): 3091-3096.
Antiperoxidant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Lipoxygenase-Inhibitor * Topoisomerase-II-Inhibitor IC100=0.2 uM Kashiwada, Y., Nonaka, G. I., Nishioka, I., Lee, J. H., Bori, I., Fukushima, Y., Bastow, K. F., Lee, K. H. 1993. Tannins as Potent Inhibitors of DNA Topoisomerase II in vitro. J Pharm Sci, 82: 487-492. Xanthine-Oxidase-Inhibitor IC50=36 uM Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
77	CHLOROGENIC-ACID	Leaf	--	--	--	Okuda, T., Yoshida, T., Hatano, T., Iwasaki, M., Kubo, M., Orime, T., Yoshizaki, M., Naruhashi, N. 1992. Hydrolysable Tannins as Chemotaxonomic Markers in the Rosaceae. Phytochemistry, 31(9): 3091-3096.
Aldose-Reductase-Inhibitor IC50=1.8 uM rat (strong activity) Yoshikawa, M., et al. 1999. Medicinal Flowers. I. Aldose Reductase Inhibitors and Three New Eudesmane-Type Sesquiterpenes, Kikkanols A, B, and C, From the Flowers of Chrysanthemum inducum L. Chem Pharm Bull, 47(3): 340-345. Allelochemic * Allergenic * Analgesic * Antiatherosclerotic * Antibacterial * Anticancer (Colon) * Anticancer (Forestomach) * Anticancer (Liver) * Anticancer (Skin) * Anticarcinogenic * Antidiabetic * AntiEBV Economic & Medicinal Plant Research, 6: 189. Antifeedant * Antigenotoxic * Antigonadotropic Jim Duke's personal files. Antihemolytic 10 uM Ohnishi, M., Morishita, H., Iwahashi, H., Toda, S., Shirataki, Y., Kimura, M., and Kido, R. 1993. Inhibitory Effects of Chlorogenic Acids on Linoleic Acid Peroxidation and Haemolysis. Phytochemistry. 36(3): 579-583. 1994. Antihepatotoxic * Antiherpetic Economic & Medicinal Plant Research, 5: 194. Antihistaminic * AntiHIV Economic & Medicinal Plant Research, 6: 189. Antihypercholesterolemic Economic & Medicinal Plant Research, 6: 189. Antihyperthyroid * Antiinflammatory Hagerman, A.E. Tannin-Protein Interactions. Phenolic Compounds in Food and Their Effects on Health, Ch.19. AntiLegionella * Antileukotriene * Antimelanogenic * Antimutagenic * Antinitrosaminic * Antioxidant IC53=200 ppm Huang, M-T., and Ferraro, T. Phenolic Compounds in Food and Cancer Prevention. Phenolic Compounds in Food and Their Effects on Health, Ch.2 p.21. Antioxidant IC80=12 uM * Antioxidant IC50=54.2 uM * Antiperoxidant IC50=36 uM Planta Medica, 57: A54, 1991. Antipolio Jim Duke's personal files. Antiradicular 10 uM Ohnishi, M., Morishita, H., Iwahashi, H., Toda, S., Shirataki, Y., Kimura, M., and Kido, R. 1993. Inhibitory Effects of Chlorogenic Acids on Linoleic Acid Peroxidation and Haemolysis. Phytochemistry. 36(3): 579-583. 1994. Antiradicular 9 x quercetin * Antiseptic * Antisunburn * Antithyroid Jim Duke's personal files. Antitumor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antitumor (Colon) * Antitumor (Forestomach) * Antitumor (Liver) * Antitumor (Skin) * Antitumor-Promoter IC25=10 uM * Antiulcer Economic & Medicinal Plant Research, 6: 189. Antiviral Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart. Autotoxic * Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Cardioprotective * Chemopreventive * Cholagogue Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp. Choleretic Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. Clastogenic Friedman, M. and Dao, L. 1990. Effect of Autoclaving and Conventional and Microwave Baking on the Ergot Alkaloid and Chlorogenic Acid Contents of Morning Glory (Ipomoea tricolor Cav. cv.) Heavenly Blue Seeds. J. Agric. Food Chem. 38: 805-808. CNS-Active Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp. CNS-Stimulant 1/6 Caffeine * Collagen-Sparing * Diuretic * Fungicide Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp. Hepatoprotective Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. Histamine-Inhibitor * Hypoglycemic * Immunostimulant * Insectifuge Tunon, H., Thorsell, W., and Bohlin, L. 1993. Mosquito Repelling Activity of Compounds Occurring in Achillea millefolium L. (Asteraceae). Economic Botany 48(2): 111-120, 1994. Interferonogenic Economic & Medicinal Plant Research, 1: 124. Juvabional Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Larvistat Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Leukotriene-Inhibitor * Lipoxygenase-Inhibitor IC23=5 mM Oszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690. Metal-Chelator McEvily, A.J., Iyengar, R., and Gross, A.T. Inhibition of Polyphenol Oxidase by Phenolic Compounds. Phenolic Compounds in Food and Their Effects on Health, Ch.25. NO-Genic * Ornithine-Decarboxylase-Inhibitor Hagerman, A.E. Tannin-Protein Interactions. Phenolic Compounds in Food and Their Effects on Health, Ch.19. Oviposition-Stimulant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Pesticide * Sunscreen * Sweetener Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. Vulnerary *
0	CHRYSANTHEMIN	Fruit	--	--	--	Torre, L. C., Barritt, B. H. 1977. Quantitative Evaluation of Rubus Fruit Anthocyanin Pigments. J. Food Sci., 42: 488.
0	CYANIDIN-3-O-BETA-D-RUTINOSIDE	Fruit	--	--	--	Torre, L. C., Barritt, B. H. 1977. Quantitative Evaluation of Rubus Fruit Anthocyanin Pigments. J. Food Sci., 42: 488.
10	ERIODICTYOL	Flower	--	--	--	Wollenweber, E., Dorr, M., Armbruster, S. 1993. Flavonoid Aglycones from Rosa centifolia cv. muscosa and Rubus phoenicolasius. Z Naturforsch Ser C, 48(11/12): 956-958.
Antibacterial Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antifeedant IC52=<1,000 ppm diet Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp. Antiinflammatory * Antioxidant * Antiperoxidant Planta Medica, 57: A110, 1991. Aphidifuge * Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Expectorant Lawrence Review of Natural Products, Mar-91. Juvabional Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Pesticide *
0	ERIODICTYOL-7-METHYL-ETHER	Flower	--	--	--	Wollenweber, E., Dorr, M., Armbruster, S. 1993. Flavonoid Aglycones from Rosa centifolia cv. muscosa and Rubus phoenicolasius. Z Naturforsch Ser C, 48(11/12): 956-958.
0	ISOKAEMPFERIDE	Flower	--	--	--	Wollenweber, E., Dorr, M., Armbruster, S. 1993. Flavonoid Aglycones from Rosa centifolia cv. muscosa and Rubus phoenicolasius. Z Naturforsch Ser C, 48(11/12): 956-958.
0	LAMBERTIANIN-C	Leaf	--	--	--	Tanaka,T., Tachibana,H., Nonaka,G., Nishioka,I., Hsu,F.L., Kohda,H., Tanaka,O. 1993. Tannins and Related Compounds. CXXII. New Dimeric, Trimeric and Tetrameric Ellagitannins, Lambertianins A-D, from Rubus lambertianus. Chem & Pharm Bull, 41(7): 1214-1220.
0	LAMBERTIANIN-D	Leaf	--	--	--	Tanaka,T., Tachibana,H., Nonaka,G., Nishioka,I., Hsu,F.L., Kohda,H., Tanaka,O. 1993. Tannins and Related Compounds. CXXII. New Dimeric, Trimeric and Tetrameric Ellagitannins, Lambertianins A-D, from Rubus lambertianus. Chem & Pharm Bull, 41(7): 1214-1220.
9	PEDUNCULAGIN	Leaf	--	--	--	*
Antihepatotoxic Okuda, T., Yoshida, T., and Hatano, T. Antioxidant Effects of Tannins and Related Polyphenols. Phenolic Compounds in Food and Their Effects on Health, Ch.7 p.93. Antilipolytic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antimutagenic Economic & Medicinal Plant Research, 6: 235. Antioxidant * Antiperoxidant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Beta-Adrenergic Receptor Blocker 10 uM Zhu, M., Phillipson, J. D., Greengrass, P. M., Bowery, N. E., Cai, Y. 1997. Plant Polyphenols: Biologically Active Compounds or Non-Selective Binders to Protein? Phytochemistry, 44(3): 441-447. Topoisomerase-I-Inhibitor 0.03 ug/ml Ooishi, K., Kato, J., Hayamizu, K. 1994. Topoisomerase Inhibitors Containing Tannins, Especially Pedunculagin, for Treatment of Cancer. Patent, Japan Kokai Tokkyo Koho-06 72,885. 7pp. Topoisomerase-II-Inhibitor IC100=0.5 uM Kashiwada, Y., Nonaka, G. I., Nishioka, I., Lee, J. H., Bori, I., Fukushima, Y., Bastow, K. F., Lee, K. H. 1993. Tannins as Potent Inhibitors of DNA Topoisomerase II in vitro. J Pharm Sci, 82: 487-492. Xanthine-Oxidase-Inhibitor IC50=18 uM Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
2	QUERCETIN-3'-METHYLETHER	Flower	--	--	--	Wollenweber, E., Dorr, M., Armbruster, S. 1993. Flavonoid Aglycones from Rosa centifolia cv. muscosa and Rubus phoenicolasius. Z Naturforsch Ser C, 48(11/12): 956-958.
Antihistaminic * Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
1	QUERCETIN-3,3'-DIMETHYLETHER	Flower	--	--	--	Wollenweber, E., Dorr, M., Armbruster, S. 1993. Flavonoid Aglycones from Rosa centifolia cv. muscosa and Rubus phoenicolasius. Z Naturforsch Ser C, 48(11/12): 956-958.
Antiviral *
1	QUERCETIN-3,3'-DIMETHYLETHER	Inflorescence	--	--	--	Wollenweber, E., Dorr, M., Armbruster, S. 1993. Flavonoid Aglycones as Glandular Products in Rosa centifolia cv. muscosa and in Rubus phoenicolasius. Z Naturforsch Ser C, 48(11/12): 956-958.
Antiviral *
1	SANGUIIN-H-11	Leaf	--	--	--	Okuda, T., Yoshida, T., Hatano, T., Iwasaki, M., Kubo, M., Orime, T., Yoshizaki, M., Naruhashi, N. 1992. Hydrolysable Tannins as Chemotaxonomic Markers in the Rosaceae. Phytochemistry, 31(9): 3091-3096.
Topoisomerase-II-Inhibitor IC100=0.2 uM Kashiwada, Y., Nonaka, G. I., Nishioka, I., Lee, J. H., Bori, I., Fukushima, Y., Bastow, K. F., Lee, K. H. 1993. Tannins as Potent Inhibitors of DNA Topoisomerase II in vitro. J Pharm Sci, 82: 487-492.
5	SANGUIIN-H-6	Leaf	--	--	--	Okuda, T., Yoshida, T., Hatano, T., Iwasaki, M., Kubo, M., Orime, T., Yoshizaki, M., Naruhashi, N. 1992. Hydrolysable Tannins as Chemotaxonomic Markers in the Rosaceae. Phytochemistry, 31(9): 3091-3096.
Antiangiogenic * Topoisomerase-I-Inhibitor IC50=0.02-5 uM Bastow, K.F., Bori, I.D., Fukushima, Y., Kashiwada, Y., Tanaka, T., Nonaka, G., Nishioka, I., Lee, K.H. 1993. Inhibition of DNA Topoisomerases by Sanguiin H-6, a Cytotoxic Dimeric Ellagitannin From Sanguisorba officinalis. Planta Medica, 59: 240-245. Topoisomerase-II-Inhibitor IC50=0.01-0.16 uM Bastow, K.F., Bori, I.D., Fukushima, Y., Kashiwada, Y., Tanaka, T., Nonaka, G., Nishioka, I., Lee, K.H. 1993. Inhibition of DNA Topoisomerases by Sanguiin H-6, a Cytotoxic Dimeric Ellagitannin From Sanguisorba officinalis. Planta Medica, 59: 240-245. Topoisomerase-II-Inhibitor IC100=0.2 uM Kashiwada, Y., Nonaka, G. I., Nishioka, I., Lee, J. H., Bori, I., Fukushima, Y., Bastow, K. F., Lee, K. H. 1993. Tannins as Potent Inhibitors of DNA Topoisomerase II in vitro. J Pharm Sci, 82: 487-492. VEGF-Inhibitor IC50=7.4 ug/ml *
0	SCOPAROL	Inflorescence	--	--	--	Wollenweber, E., Dorr, M., Armbruster, S. 1993. Flavonoid Aglycones as Glandular Products in Rosa centifolia cv. muscosa and in Rubus phoenicolasius. Z Naturforsch Ser C, 48(11/12): 956-958.

^*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.

Plant Rubus phoenicolasius (Rosaceae)

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