Pelargonium roseum | Plant | Dr. Duke's Phytochemical and Ethnobotanical Databases

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Common name(s)

Scented Geranium

How used

Medicinal

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Activities: 108

Chemicals w/Activities: 13

All Chemicals: 19

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List of all chemical
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# Activity	Chemical Name	Part	Low PPM	High PPM	StdDev	^*Reference
0	(E)-ROSE-OXIDE	Shoot	--	36.0	--	*
0	(Z)-LINALOOL-OXIDE	Shoot	--	54.0	--	*
0	(Z)-ROSE-OXIDE	Shoot	--	126.0	--	*
28	ALPHA-PINENE	Shoot	--	126.0	-0.13	*
Allelochemic * Allergenic * Antiacne * Antibacterial * Antifeedant * Antiflu Economic & Medicinal Plant Research, 5: 195. Antiinflammatory 500 mg/kg * Antipneumonic * Antiseptic * Antispasmodic * Antistaphylococcic * Antiviral Economic & Medicinal Plant Research, 5: 195. Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Coleoptophile * Expectorant Michael Castleman 1991. The Healing Herbs. Rodale Press, Emmaus, PA 436 pp. FLavor FEMA 15-150 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Herbicide IC50=30 uM Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp. Insecticide 0.82 uM/fly * Insectifuge 50 ppm * Insectiphile J. Stored. Prod. Res., 22:141, 1986. Irritant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. P450-2B1-Inhibitor IC50=0.087 uM * Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Pesticide * Sedative Lawrence Review of Natural Products, Jun-90. Spasmogenic * Tranquilizer Lawrence Review of Natural Products, Jun-90. Transdermal *
13	BETA-PINENE	Shoot	--	18.0	-0.12	*
Allergenic * Antiinflammatory * Antiseptic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. Antispasmodic * Candidicide * FLavor FEMA 15-600 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Herbicide Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp. Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253. Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Pesticide * Spasmogenic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp. Transdermal *
15	CITRONELLOL	Shoot	--	4050.0	0.14	*
Allergenic * Antibacterial * Antiseptic * Antistaphylococcic * Antistreptococcic * Candidicide * FLavor FEMA 1-50 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Fungicide HerbalGram No. 17. Herbicide IC50=160 uM Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp. Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253. Nematicide MLC=100 ug/ml Shoyakugaku Zasshi, 44: 183. Perfumery Merck 11th Edition Pesticide * Sedative Wagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176) Trichomonicide LD100=300 ug/ml *
1	CITRONELLYL-FORMATE	Shoot	--	1548.0	1.00	*
FLavor FEMA 4-100 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
0	EO	Shoot	--	18000.0	0.71	*
13	GERANIAL	Shoot	--	252.0	0.04	*
Antiaflatoxin * Antibacterial Onawunmi, G.O., Yisak, W-A., Ogunlana,* E.O. 1984. Antibacterial Constituents In The Essential Oil Of Cymbopogon citratus (DC.) Stapf. Journal of Ethnopharmacology, 12: 279-286, 1984. AntiEBV IC50=16 uM * Antitumor (Colon) * Antitumor (Skin) * Antiviral IC50=16 uM * Antiyeast * Chemopreventive * Estrogenic * Fungicide * Glutathionigenic * Pesticide * Spasmolytic *
35	GERANIOL	Shoot	--	3276.0	1.54	*
Allergenic * Anthelmintic Madaus, G. 1976. Lehrbuch der Biologischen Hilfmittel. Vol,. 1-3. 2862 pp. (+ 144 p. index). Georg Olms Verlag, Hildescheim. Reprint of 1938 Madaus. Antibacterial MIC=64 ug/ml * Antibacterial MBC=800 ug/ml * Antibacterial MIC=400 ug/ml Muroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105. Anticancer (Pancreas) IC50=265 uM * Anticariogenic MIC=400 ug/ml Muroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105. Antimelanomic IC50=150 uM/l * Antisalmonella MIC=400 ug/ml * Antiseptic MIC=64 ug/ml * Antiseptic 400-800 ug/ml * Antiseptic 7 x phenol Wagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176) Antispasmodic Buchbauer, G., Jirovetz, L., Nikiforov, A., Remberg, G., Raverdino, V. 1989. Headspace-Analysis and Aroma Compounds of Austrian Hay-Blossoms (Flores Graminis, Graminis Flos) used in Aromatherapy. J. Ess. Oil Res., 2: 185-191, 1990. Antitubercular MIC=64 ug/ml Antitumor Yu, S.G., Anderson, P.J., and Elson, C.E. 1995. Efficacy of B-Ionone in the Chemoprevention of Rat Mammary Carcinogenesis. J. Agric. Food Chem. 43: 2144-2147. Antitumor (Pancreas) IC50=265 uM * Ascaricide Madaus, G. 1976. Lehrbuch der Biologischen Hilfmittel. Vol,. 1-3. 2862 pp. (+ 144 p. index). Georg Olms Verlag, Hildescheim. Reprint of 1938 Madaus. Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Candidicide * CNS-Stimulant List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979. Embryotoxic * Emetic 3 x ipecac Lawrence Review of Natural Products, Sep-97. Expectorant Madaus, G. 1976. Lehrbuch der Biologischen Hilfmittel. Vol,. 1-3. 2862 pp. (+ 144 p. index). Georg Olms Verlag, Hildescheim. Reprint of 1938 Madaus. FLavor FEMA 1-10 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Fungicide IC93=2 mM Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp. Herbicide IC100-2,000 uM Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp. Insectifuge 50 ppm * Insectiphile Merck 11th Edition Mycobactericide MIC=64 ug/ml * Nematicide IC86=100 ug/ml Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp. Nematicide MLC=1,000 ug/ml Shoyakugaku Zasshi, 44: 183. Perfumery Merck 11th Edition Pesticide * Sedative * Trichomonicide LD100=300 ug/ml *
0	GERANOIC-ACID	Shoot	--	18.0	--	*
2	GERANYL-FORMATE	Shoot	--	1152.0	--	*
FLavor FEMA 1-10 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
0	GERANYL-TIGLATE	Shoot	--	180.0	1.00	*
3	ISOMENTHONE	Shoot	--	1188.0	-0.32	*
Antiacetylcholinesterase IC50=1.6 mM * Antioxidant * Antiradicular *
53	LINALOOL	Shoot	--	1962.0	-0.15	*
Acaricide C90=<15 ul/l (=<15 ppm * Allergenic * Analgesic * Anesthetic 0.01-1 ug/ml * Antiacetylcholinesterase * Antiallergic Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. Antianaphylactic * Antibacterial MIC=1,600 ug/ml * Anticariogenic MIC=1,600 ug/ml Muroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105. Anticolic * Anticonvulsant 200 mg/kg ipr mus * Antiedemic * Antiglutamaergic * Antihistaminic Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. Antiinflammatory * Antileukemic IC50=3.5-4.2 ug/ml Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46. Antilymphomic IC50=3.5-4.2 ug/ml Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46. Antimange * Antimite * Antimutagenic * Antiseptic 5 x phenol Wagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176) Antishock Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. Antispasmodic Buchbauer, G., Jirovetz, L., Nikiforov, A., Remberg, G., Raverdino, V. 1989. Headspace-Analysis and Aroma Compounds of Austrian Hay-Blossoms (Flores Graminis, Graminis Flos) used in Aromatherapy. J. Ess. Oil Res., 2: 185-191, 1990. Antiviral Barbituate-Synergist * Bronchorelaxant Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Candidistat * Carminative * CNS-Depressant * Culicide LC50=156-194 mg/l * Cytotoxic * Expectorant Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. FLavor FEMA 2-40 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Fungicide Acta Botanica Sinica, 32: 49. GABA-nergic * Hypnotic * Hypothermic * Insecticide LC50=156-194 mg/l * Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253. Larvicide LC50=156-194 mg/l * Mosquitofuge > Deet * Motor-Depressant Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC Nematicide MLC=1 mg/ml Shoyakugaku Zasshi, 44: 183. Perfumery Merck 11th Edition Pesticide * Prooxidant Charalambous, G. (Ed.). 1994. Spices, Herbs and Edible Fungi. Elsevier Science B. V. Amsterdam. 764 pp. Sedative 200 mg/kg ipr mus (1% as active as diazepam) * Sedative ED=1-32 mg/kg Wagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176) Termitifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Trichomonicide LD100=600 ug/ml * Tumor-Promoter *
30	MENTHONE	Shoot	--	612.0	-0.72	*
Acaricide * Allelopathic * Analgesic * Antiacetylcholinesterase IC50=1.4 mM * Antiaggregant IC50=750 * Antiallergic J. Food Hyg. Soc. Jap. 33(6): 569. Antibacillary MIC=1.25 mg/ml * Antibacterial MIC=0.625-5 mg/ml * Antiescherichic MIC=5 mg/ml * Antihistaminic J. Food Hyg. Soc. Jap. 33(6): 569. Antilisteria MIC=1.25 mg/ml * Antisalmonella MIC=5 mg/ml * Antiseptic 2.25 x phenol Wagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176) Antispasmodic ED50=0.044 mg/ml Fitoterapia No.59-1984. Antistaphylococcic MIC=0.625-2.5 mg/ml * Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Candidicide MIC=2.5 mg/ml * Cerebrotoxic orl man J. Aromatherapy 4: 24. Culicide LC50=156-194 mg/l * FLavor FEMA 5-50 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Fungicide * Insecticide LC50=156-194 mg/l * Larvicide LC50=156-194 mg/l * Mutagenic * Nematicide MLC=1 mg/ml Shoyakugaku Zasshi, 44: 183. Perfumery Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Pesticide * Psychoactive * Sedative Ortiz de Urbina, A.V., Martin, M.L., Montero, M.J., Moran, A., and San Roman, L. 1988. Sedating and Antipyretic Activity of the Essential Oil of Calamintha sylvatica subsp. Ascendens. Journal of Ethnopharmacology, 25: 165-171, 1989. Trichomonicide LD100=600 ug/ml
4	NERAL	Shoot	--	18.0	-0.52	*
Antibacterial Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp. Antispasmodic * Pesticide * Termiticide LD100=5 mg/g *
10	NEROL	Shoot	--	216.0	-0.20	*
Antibacterial HerbalGram No. 17. Antihelicobacter * Antiseptic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. Antiulcer * Estrogenic * FLavor FEMA 1-20 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Perfumery Merck 11th Edition Pesticide * Sedative Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253. Trichomonicide ED100=300 ug/ml *
23	TERPINEN-4-OL	Shoot	--	1080.0	0.28	*
Allelopathic Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands. Antiacetylcholinesterase IC21-24=1.2 mM * Antiacne * Antiallergic * Antiasthmatic Chin. J. Tuber. Respir. Dis., 4:203, 1982. Antibacterial * Antioxidant * Antiseptic Flav. & Frag. J. 9: 129. Antispasmodic * Antitussive Chin. J. Tuber. Respir. Dis. Antiulcer * Bacteriostatic Chin. J. Tuber. Respir. Dis. Diuretic 0.1 ml/rat * Fungicide * Herbicide IC50=22 uM Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp. Herbicide IC50=200 mM Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp. Insectifuge * Irritant Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp. Nematicide MLC=1 mg/ml Shoyakugaku Zasshi, 44: 183. Pesticide * Renoirritant Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp. Spermicide ED100=0.015 * Vulnerary Lawrence Review of Natural Products, Jan-91.

^*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.

Plant Pelargonium roseum (Geraniaceae)

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