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Plant Crataegus monogyna (Rosaceae)
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Common name(s)
English Hawthorn, Hawthorn
How used
Medicinal
Data Views
| # Activity | Chemical Name | Part | Low PPM | High PPM | StdDev | *Reference |
|---|---|---|---|---|---|---|
| 30 | (+)-CATECHIN | Plant | -- | -- | -- | Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. |
|
ACE-Inhibitor 0.24 mg/ml rbt (weak activity)
*
ACE-Inhibitor IC50=0.155 mM/l
*
Antiaggregant IC68=200 ug/ml
*
Anticoagulant
*
Anticomplementary 1/2 aspirin
*
AntiHIV EC50=4 ug/ml
*
Antiinflammatory IC50=40-943 uM (cf indomethacin IC50=1 uM)
*
Antimutagenic ID50=50-100 nM
Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
Antioxidant
*
Antiperoxidant
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiprostaglandin IC50=40-943 uM (cf indomethacin IC50=1 uM)
*
Antiradicular
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiulcer
*
Beta-Adrenergic Receptor Blocker 10 uM (weak activity)
Zhu, M., Phillipson, J. D., Greengrass, P. M., Bowery, N. E., Cai, Y. 1997. Plant Polyphenols: Biologically Active Compounds or Non-Selective Binders to Protein? Phytochemistry, 44(3): 441-447.
cAMP-Phosphodiesterase-Inhibitor
*
Cancer-Preventive
Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Cardiotonic
*
COX-1-Inhibitor IC50=183-279 uM (cf indomethacin IC50=1 uM)
*
COX-2-Inhibitor IC50=546-5,910 uM (cf indomethacin IC50=1 uM)
*
Cyclooxygenase-Inhibitor
*
Cytotoxic TC50=>100 ug/ml
*
Dermatitigenic
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Hemostat
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Hepatoprotective
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Immunostimulant
Economic & Medicinal Plant Research, 1: 124.
Neuroprotective 1-10 uM
*
NO-Inhibitor IC11=250 uM
*
Phagocytotic
Economic & Medicinal Plant Research, 1: 124.
Vasoconstrictor
Leung, A.Y., Encyclopedia of Common Natural Ingredients Used in Food, Drugs, and Cosmetics, John Wiley & Sons, New York, 1980.
Xanthine-Oxidase-Inhibitor
Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill
Livinston, Edinburgh.
|
||||||
| 38 | (-)-EPICATECHIN | Plant | -- | -- | -- | Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. |
|
5-Lipoxygenase-Inhibitor IC50=22-50 uM/l
*
ACE-Inhibitor IC50=0.216 mM/l
*
ACE-Inhibitor 0.5 mg/ml rbt (weak activity)
*
Allelochemic
Hanke, F. J., Natural Products as a Resource for Biologically Active Compounds, Thesis, U. Cal (Santa Cruz), 1986, 252 pp
Antiaggregant
*
Antianaphylactic
*
Antibacterial
*
Antidiabetic 30 mg/kg rat
*
AntiEBV
Economic & Medicinal Plant Research, 6: 189.
Antihepatitic
Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
AntiHIV EC50=2 ug/ml
*
Antihyperglycemic
*
Antiinflammatory
*
Antileukemic
Economic & Medicinal Plant Research, 6: 189.
Antileukotriene
*
Antilipoperoxidant
*
Antimutagenic
*
Antioxidant IC50=6.3 ug/ml
*
Antiperoxidant
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiviral EC50=2 ug/ml
*
Beta-Adrenergic Receptor Blocker 10 uM
Zhu, M., Phillipson, J. D., Greengrass, P. M., Bowery, N. E., Cai, Y. 1997. Plant Polyphenols: Biologically Active Compounds or Non-Selective Binders to Protein? Phytochemistry, 44(3): 441-447.
Cancer-Preventive
Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Cardiotonic
*
Choline-Sparing
*
COMP-Inhibitor
Dullo, A. G., et al. 1999. Efficacy of a green tea extract rich in catechin polyphenols and caffeine in increasing 24-h energy expenditure and fat oxidation in humans. Am. J. Clinical Nutrition, 70: 1040-1045.
Cytotoxic TC50=>100 ug/ml
*
Hypocholesterolemic
*
Hypoglycemic
*
Immunostimulant
*
Insulinogenic
Economic & Medicinal Plant Research, 6: 170.
Lipoxygenase-1-Inhibitor IC50=60 mM
*
Lipoxygenase-Inhibitor IC50=140 uM
Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
Lipoxygenase-Inhibitor IC97=5 mM
Oszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690.
Pancreatogenic
*
Pesticide
*
Reverse-Transcriptase-Inhibitor 10 ng/ml
McKenna, D. J., Hughes, K., and Jones, K. 2000. Green Tea Monograph. Alternative Therapies, 6(3): 61-82.
Vasodilator uM
McKenna, D. J., Hughes, K., and Jones, K. 2000. Green Tea Monograph. Alternative Therapies, 6(3): 61-82.
Xanthine-Oxidase-Inhibitor IC50=>40
Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
|
||||||
| 0 | 2''-O-RHAMNOSIDE-ISOORIENTIN | Leaf | -- | -- | -- | * |
| 0 | 2''-O-RHAMNOSIDE-ISOVITEXIN | Leaf | -- | -- | -- | * |
| 0 | 2''-O-RHAMNOSYL-ISOORIENTIN | Flower | -- | -- | -- | * |
| 0 | 2''-O-RHAMNOSYL-ISOVITEXIN | Flower | -- | -- | -- | * |
| 0 | 2''-O-RHAMNOSYL-ORIENTIN | Flower | -- | -- | -- | * |
| 0 | 2''-O-RHAMNOSYL-VITEXIN | Flower | -- | -- | -- | * |
| 0 | 2-ALPHA-HYDROXY-OLEANOLIC-ACID | Plant | -- | -- | -- | Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. |
| 0 | 2-PHENYLCHROMONE | Flower | -- | -- | -- | * |
| 0 | 4'-ACETYL-2-RHAMNOSIDE | Plant | -- | 5000.0 | -- | * |
| 0 | ACANTOLIC-ACID | Plant | -- | -- | -- | Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. |
| 19 | ACETYL-CHOLINE | Plant | -- | -- | -- | Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. |
|
Allergenic
*
Antiamblyopic
*
Antidiuretic
*
Antiileus
*
Antitachycardic
*
Cardiodepressant
Martindale's 29th
Cerebrostimulant
*
Histaminic
*
Hypotensive
*
Miotic
Martindale's 29th
Myocontractant 2 uM
*
Myopic
*
Myotonic
Martindale's 29th
Neurotransmitter
*
Parasympathomimetic 0.002 mg/kg ivn rat
Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
Peristaltic
*
Sialogogue
*
Spasmogenic Antidote=600 ug atropine sulfate ivn ims scu hmn
*
Vasodilator
*
|
||||||
| 11 | ADENINE | Plant | -- | -- | -- | Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. |
|
Antianemic 1.5 g/day
Martindale's 28th
Antigranulocytopenic
*
Antiviral
*
CNS-Stimulant
*
Diuretic
*
Hyperuricemic
Martindale's 28th
Insectifuge
Tunon, H., Thorsell, W., and Bohlin, L. 1993. Mosquito Repelling Activity of Compounds Occurring in Achillea millefolium L. (Asteraceae). Economic Botany 48(2): 111-120, 1994.
Lithogenic
*
Myocardiotonic
*
Pesticide
*
Vasodilator
*
|
||||||
| 28 | ADENOSINE | Plant | -- | -- | -- | Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. |
|
Analgesic
*
Antiaggregant
*
Antiarrhythmic
Merck 11th Edition
Antidiuretic
LAWSON in Koch, H. P. and Lawson, L. D., eds. 1996. Garlic- The
Science and therapeutic application of Allium sativum L. and related species. Williams & Wilkins, Baltimore. 329 pp.
Antiendotoxic 500 mg/kg ipr mus
Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
Antihypertensive
LAWSON in Koch, H. P. and Lawson, L. D., eds. 1996. Garlic- The
Science and therapeutic application of Allium sativum L. and related species. Williams & Wilkins, Baltimore. 329 pp.
Antiinsomniac
*
Antilipolytic
*
Antispasmodic
*
Antitachycardic 50-250 ug/kg/ivn
Martindale's 29th
Anxiolytic
*
Arteriodilator
*
Glucogonogenic
LAWSON in Koch, H. P. and Lawson, L. D., eds. 1996. Garlic- The
Science and therapeutic application of Allium sativum L. and related species. Williams & Wilkins, Baltimore. 329 pp.
Hypocholesterolemic
LAWSON in Koch, H. P. and Lawson, L. D., eds. 1996. Garlic- The
Science and therapeutic application of Allium sativum L. and related species. Williams & Wilkins, Baltimore. 329 pp.
Hypoglycemic
*
Hypotensive
LAWSON in Koch, H. P. and Lawson, L. D., eds. 1996. Garlic- The
Science and therapeutic application of Allium sativum L. and related species. Williams & Wilkins, Baltimore. 329 pp.
Immunomodulator
*
Insulinic
*
Laxative
*
Lipolytic
LAWSON in Koch, H. P. and Lawson, L. D., eds. 1996. Garlic- The
Science and therapeutic application of Allium sativum L. and related species. Williams & Wilkins, Baltimore. 329 pp.
Myorelaxant
Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
PAF-Inhibitor 0.024 ug/ml
*
PAF-Inhibitor IC50=90 nM
*
Pyrogenic 0.09 mg/kg ivn hmn
Conradson, T. B. G., Dixon, C. M. S., Clarke, B., Barnes, P. J. 1987. Cardiovascular Effects of Infused Adenosine in Man: Potentiation by Dipyridamole. Acta Physiol Scand, 129(3): 387-391.
Respirastimulant
Martindale's 29th
Secretomotor
*
Sedative
Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Vasodilator
*
|
||||||
| 33 | AESCULIN | Inflorescence | -- | -- | -- | * |
|
Aldose-Reductase-Inhibitor 10 ug/ml cow
Okada,Y,et al.1995.Search for Naturally Occurring Substances to Prevent the Complications of Diabetes.II.Inhibitory Effect of Coumarin and Flavonoid Derivatives on Bovine Lens Aldose Reductase and Rabbit Platelet Aggregation.Chem Pharm Bull43(8):1385-1387
Analgesic
*
Antiacrocyanotic
*
Antiaging
*
Antialopecic
*
Antiarthritic
*
Anticapillary-Fragility
Bisset, N.G., ed. 1994. Herbal Drugs and Phytopharmaceuticals. CRC Press. Boca Raton, FL. 566 pp.
Anticellulitic
*
AntiCVS
*
Antidermatitic
*
Antierythemic 4 mg orl man
*
Antihemorrhoidal
*
Antihistaminic
*
Antiinflammatory
*
Antioxidant
Jim Duke's personal files.
Antipanniculopathic
*
Antipyretic
*
AntiRaynaud's
*
Antiseborrheic
*
Bacteristat
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Cancer-Preventive
Jim Duke's personal files.
Cardiotonic
*
Choleretic
Fitoterapia No.5-1986.
Cosmetic
*
Diuretic
*
Hypertensive
*
Lipoxygenase-Inhibitor
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Microvasculokinetic
*
Sunscreen
*
Sunscreen IC39=20 mg/l
Lazarova*, G., Kostova, I., Neychev, H. 1992. Photodynamic damage prevention by some hydroxycoumarins. Fitoterapia 64(2): 134-136, 1993.
Sunscreen IC26=50 mg/l
*
Toxic
*
Vasoprotective
*
|
||||||
| 0 | AMINOPURINE | Inflorescence | -- | -- | -- | * |
| 101 | APIGENIN | Leaf | -- | -- | -- | * |
|
11B-HSD-Inhibitor
*
AntiADD
*
Antiaflatoxin IC50=9.52 uM
*
Antiaflatoxin IC50=2.57 ppm
*
Antiaggregant
*
Antiaging
*
Antiallergic
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiangiogenic 4 uM
*
Antiarrhythmic
*
Antibacterial
Recio, M. C., Rios, J. L., and Villar, A., A review of some antimicrobial compounds isolated from medicinal plants reported in the literature 1978-1988, Phytotherapy Research, 3(4), 1989, 117-125.
Anticancer (Lung)
*
Anticomplementary
*
Antidermatitic
Bisset, N.G., ed. 1994. Herbal Drugs and Phytopharmaceuticals. CRC Press. Boca Raton, FL. 566 pp.
Antiestrogenic
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiherpetic 20-54 ug/ml
*
Antihistaminic IC50=10-35 uM
*
AntiHIV IC50=143 ug/ml
*
AntiHIV IC72=200 ug/ml
*
Antiinflammatory IC~65=1,000 uM
*
Antiinflammatory #NAME?
*
Antileukemic 20-50 uM
*
Antimelanomic 1-50 uM
*
Antimetastatic 1-50 uM
*
Antimutagenic ID50=10-40 nM
Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
Antimutagenic ID50=0.55 ug/ml
*
Antioxidant 1.5 x Vit. E
*
Antioxidant IC28.5=62.5 ug/ml
*
Antiperistaltic
*
Antiproliferant IC50=155 uM
*
Antiproliferant 1-50 uM
*
Antispasmodic EC50=1-5 uM
*
Antistress 10 mg/kg
*
Antithyroid
Jim Duke's personal files.
Antitumor 1-50 uM
*
Antitumor (Breast) 1-50 uM
*
Antitumor (Lung)
*
Antitumor (Skin)
*
Antiviral 20-54 ug/ml
*
Anxiolytic 10 mg/kg
*
Apoptotic 12-60 uM
*
Aromatase-Inhibitor IC65=1 uM/l
Journal of Medicinal Food 2: 235.1999.
Beta-Glucuronidase-Inhibitor IC50=~40 uM
*
Calcium-Antagonist?
Biochimica & Biophysica Acta, 1115: 69, 1991.
Cancer-Preventive
Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Choleretic
*
CNS-Depressant
*
COX-1-Inhibitor IC65=1,000 uM
*
COX-2-Inhibitor IC>65=1,000 uM
*
COX-2-Inhibitor IC50=<15 uM
*
COX-2-Inhibitor <40 uM
*
Cyclooxygenase-Inhibitor
*
Cytochrome-P450-1A1-Inhibitor
*
Cytotoxic IC50=9.5 uM
*
Cytotoxic IC88=10 ug/ml
Planta Medica, 57: A113, 1991.
Cytotoxic 1-50 uM
*
Deiodinase-Inhibitor
Jim Duke's personal files.
Differentiator MIC=30 uM
*
Differentiator IC40=40 uM
*
Diuretic
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
DNA-Protective
*
Estrogenic EC50=1 uM
*
Estrogenic EC50=0.1-25 uM/l
Journal of Medicinal Food 2: 227.1999.
Estrogenic 16% genistein
*
HIF-1alpha-Inhibitor
*
Hyaluronidase-Inhibitor IC50+=50-250 uM
*
Hypotensive
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
ICAM-1-Inhibitor
*
IKK-Inhibitor
*
iNOS-Inhibitor IC50=<15 uM
*
Inotropic
*
Interleukin-6-Inhibitor
*
MAO-Inhibitor
*
MAPK-Inhibitor
*
Musculotropic
Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
Mutagenic
*
Myorelaxant
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
NADH-Oxidase-Inhibitor
*
NF-kB-Inhibitor
*
NO-Synthase-Inhibitor 5-50 uM
*
Nodulation-Signal
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Ornithine-Decarboxylase-Inhibitor
*
P21-Inducer 10-70 uM
*
Pesticide
*
PKC-Inhibitor IC50=10 uM
*
Polyamine-Synthesis-Inhibitor
*
Progestational
*
Protein-Kinase-C-Inhibitor IC50=10-40 uM
*
PTK-Inhibitor 10-100 uM
*
Quinone-Reductase-Inducer 20 uM
Uda, Y., Price, K. R., Williamson, G., Rhodes, M. J. C. 1997. Induction of the Anticarcinogenic Marker Enzyme, Quinone Reductase, in Murine Hepatoma Cells In Vitro by Flavonoids. Cancer Lett., 120 (2): 213-216.
Radioprotective
*
Sedative 30-100 mg/kg
*
Sunscreen
*
TNF-alpha-Inhibitor IC50=3.27 uM
*
Topoisomerase-I-Inhibitor
Santti, R., Makela, S., Strauss, L., Korman, J., Kostian, M. L. 1998. Phytoestrogens: Potential Endocrine Disruptors in Males. Toxicol Ind Health, 14: 223-237.
Topoisomerase-II-Inhibitor IC45=180 uM
*
Topoisomerase-II-Inhibitor IC28=18 uM
*
Topoisomerase-II-Inhibitor 50 ug/ml
Azuma, Y., Onishi, Y., Sato, Y., Kizaki, H. 1995. Effects of Protein Tyrosine Kinase Inhibitors With Different Modes of Action on Topoisomerase Activity and Death of IL-2-Dependent CTLL-2-Cells. J Biochemistry, 118: 312-318.
Uterotrophic EC50=0.1-25 uM/l
Journal of Medicinal Food 2: 227.1999.
Vasodilator
*
VEGF-Inhibitor IC50=2-7 uM
*
Xanthine-Oxidase-Inhibitor 0.36 uM
*
|
||||||
| 101 | APIGENIN | Fruit | -- | -- | -- | Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp. |
|
11B-HSD-Inhibitor
*
AntiADD
*
Antiaflatoxin IC50=9.52 uM
*
Antiaflatoxin IC50=2.57 ppm
*
Antiaggregant
*
Antiaging
*
Antiallergic
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiangiogenic 4 uM
*
Antiarrhythmic
*
Antibacterial
Recio, M. C., Rios, J. L., and Villar, A., A review of some antimicrobial compounds isolated from medicinal plants reported in the literature 1978-1988, Phytotherapy Research, 3(4), 1989, 117-125.
Anticancer (Lung)
*
Anticomplementary
*
Antidermatitic
Bisset, N.G., ed. 1994. Herbal Drugs and Phytopharmaceuticals. CRC Press. Boca Raton, FL. 566 pp.
Antiestrogenic
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiherpetic 20-54 ug/ml
*
Antihistaminic IC50=10-35 uM
*
AntiHIV IC50=143 ug/ml
*
AntiHIV IC72=200 ug/ml
*
Antiinflammatory IC~65=1,000 uM
*
Antiinflammatory #NAME?
*
Antileukemic 20-50 uM
*
Antimelanomic 1-50 uM
*
Antimetastatic 1-50 uM
*
Antimutagenic ID50=10-40 nM
Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
Antimutagenic ID50=0.55 ug/ml
*
Antioxidant 1.5 x Vit. E
*
Antioxidant IC28.5=62.5 ug/ml
*
Antiperistaltic
*
Antiproliferant IC50=155 uM
*
Antiproliferant 1-50 uM
*
Antispasmodic EC50=1-5 uM
*
Antistress 10 mg/kg
*
Antithyroid
Jim Duke's personal files.
Antitumor 1-50 uM
*
Antitumor (Breast) 1-50 uM
*
Antitumor (Lung)
*
Antitumor (Skin)
*
Antiviral 20-54 ug/ml
*
Anxiolytic 10 mg/kg
*
Apoptotic 12-60 uM
*
Aromatase-Inhibitor IC65=1 uM/l
Journal of Medicinal Food 2: 235.1999.
Beta-Glucuronidase-Inhibitor IC50=~40 uM
*
Calcium-Antagonist?
Biochimica & Biophysica Acta, 1115: 69, 1991.
Cancer-Preventive
Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Choleretic
*
CNS-Depressant
*
COX-1-Inhibitor IC65=1,000 uM
*
COX-2-Inhibitor IC>65=1,000 uM
*
COX-2-Inhibitor IC50=<15 uM
*
COX-2-Inhibitor <40 uM
*
Cyclooxygenase-Inhibitor
*
Cytochrome-P450-1A1-Inhibitor
*
Cytotoxic IC50=9.5 uM
*
Cytotoxic IC88=10 ug/ml
Planta Medica, 57: A113, 1991.
Cytotoxic 1-50 uM
*
Deiodinase-Inhibitor
Jim Duke's personal files.
Differentiator MIC=30 uM
*
Differentiator IC40=40 uM
*
Diuretic
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
DNA-Protective
*
Estrogenic EC50=1 uM
*
Estrogenic EC50=0.1-25 uM/l
Journal of Medicinal Food 2: 227.1999.
Estrogenic 16% genistein
*
HIF-1alpha-Inhibitor
*
Hyaluronidase-Inhibitor IC50+=50-250 uM
*
Hypotensive
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
ICAM-1-Inhibitor
*
IKK-Inhibitor
*
iNOS-Inhibitor IC50=<15 uM
*
Inotropic
*
Interleukin-6-Inhibitor
*
MAO-Inhibitor
*
MAPK-Inhibitor
*
Musculotropic
Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
Mutagenic
*
Myorelaxant
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
NADH-Oxidase-Inhibitor
*
NF-kB-Inhibitor
*
NO-Synthase-Inhibitor 5-50 uM
*
Nodulation-Signal
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Ornithine-Decarboxylase-Inhibitor
*
P21-Inducer 10-70 uM
*
Pesticide
*
PKC-Inhibitor IC50=10 uM
*
Polyamine-Synthesis-Inhibitor
*
Progestational
*
Protein-Kinase-C-Inhibitor IC50=10-40 uM
*
PTK-Inhibitor 10-100 uM
*
Quinone-Reductase-Inducer 20 uM
Uda, Y., Price, K. R., Williamson, G., Rhodes, M. J. C. 1997. Induction of the Anticarcinogenic Marker Enzyme, Quinone Reductase, in Murine Hepatoma Cells In Vitro by Flavonoids. Cancer Lett., 120 (2): 213-216.
Radioprotective
*
Sedative 30-100 mg/kg
*
Sunscreen
*
TNF-alpha-Inhibitor IC50=3.27 uM
*
Topoisomerase-I-Inhibitor
Santti, R., Makela, S., Strauss, L., Korman, J., Kostian, M. L. 1998. Phytoestrogens: Potential Endocrine Disruptors in Males. Toxicol Ind Health, 14: 223-237.
Topoisomerase-II-Inhibitor IC45=180 uM
*
Topoisomerase-II-Inhibitor IC28=18 uM
*
Topoisomerase-II-Inhibitor 50 ug/ml
Azuma, Y., Onishi, Y., Sato, Y., Kizaki, H. 1995. Effects of Protein Tyrosine Kinase Inhibitors With Different Modes of Action on Topoisomerase Activity and Death of IL-2-Dependent CTLL-2-Cells. J Biochemistry, 118: 312-318.
Uterotrophic EC50=0.1-25 uM/l
Journal of Medicinal Food 2: 227.1999.
Vasodilator
*
VEGF-Inhibitor IC50=2-7 uM
*
Xanthine-Oxidase-Inhibitor 0.36 uM
*
|
||||||
| 101 | APIGENIN | Flower | -- | -- | -- | * |
|
11B-HSD-Inhibitor
*
AntiADD
*
Antiaflatoxin IC50=9.52 uM
*
Antiaflatoxin IC50=2.57 ppm
*
Antiaggregant
*
Antiaging
*
Antiallergic
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiangiogenic 4 uM
*
Antiarrhythmic
*
Antibacterial
Recio, M. C., Rios, J. L., and Villar, A., A review of some antimicrobial compounds isolated from medicinal plants reported in the literature 1978-1988, Phytotherapy Research, 3(4), 1989, 117-125.
Anticancer (Lung)
*
Anticomplementary
*
Antidermatitic
Bisset, N.G., ed. 1994. Herbal Drugs and Phytopharmaceuticals. CRC Press. Boca Raton, FL. 566 pp.
Antiestrogenic
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiherpetic 20-54 ug/ml
*
Antihistaminic IC50=10-35 uM
*
AntiHIV IC50=143 ug/ml
*
AntiHIV IC72=200 ug/ml
*
Antiinflammatory IC~65=1,000 uM
*
Antiinflammatory #NAME?
*
Antileukemic 20-50 uM
*
Antimelanomic 1-50 uM
*
Antimetastatic 1-50 uM
*
Antimutagenic ID50=10-40 nM
Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
Antimutagenic ID50=0.55 ug/ml
*
Antioxidant 1.5 x Vit. E
*
Antioxidant IC28.5=62.5 ug/ml
*
Antiperistaltic
*
Antiproliferant IC50=155 uM
*
Antiproliferant 1-50 uM
*
Antispasmodic EC50=1-5 uM
*
Antistress 10 mg/kg
*
Antithyroid
Jim Duke's personal files.
Antitumor 1-50 uM
*
Antitumor (Breast) 1-50 uM
*
Antitumor (Lung)
*
Antitumor (Skin)
*
Antiviral 20-54 ug/ml
*
Anxiolytic 10 mg/kg
*
Apoptotic 12-60 uM
*
Aromatase-Inhibitor IC65=1 uM/l
Journal of Medicinal Food 2: 235.1999.
Beta-Glucuronidase-Inhibitor IC50=~40 uM
*
Calcium-Antagonist?
Biochimica & Biophysica Acta, 1115: 69, 1991.
Cancer-Preventive
Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Choleretic
*
CNS-Depressant
*
COX-1-Inhibitor IC65=1,000 uM
*
COX-2-Inhibitor IC>65=1,000 uM
*
COX-2-Inhibitor IC50=<15 uM
*
COX-2-Inhibitor <40 uM
*
Cyclooxygenase-Inhibitor
*
Cytochrome-P450-1A1-Inhibitor
*
Cytotoxic IC50=9.5 uM
*
Cytotoxic IC88=10 ug/ml
Planta Medica, 57: A113, 1991.
Cytotoxic 1-50 uM
*
Deiodinase-Inhibitor
Jim Duke's personal files.
Differentiator MIC=30 uM
*
Differentiator IC40=40 uM
*
Diuretic
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
DNA-Protective
*
Estrogenic EC50=1 uM
*
Estrogenic EC50=0.1-25 uM/l
Journal of Medicinal Food 2: 227.1999.
Estrogenic 16% genistein
*
HIF-1alpha-Inhibitor
*
Hyaluronidase-Inhibitor IC50+=50-250 uM
*
Hypotensive
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
ICAM-1-Inhibitor
*
IKK-Inhibitor
*
iNOS-Inhibitor IC50=<15 uM
*
Inotropic
*
Interleukin-6-Inhibitor
*
MAO-Inhibitor
*
MAPK-Inhibitor
*
Musculotropic
Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
Mutagenic
*
Myorelaxant
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
NADH-Oxidase-Inhibitor
*
NF-kB-Inhibitor
*
NO-Synthase-Inhibitor 5-50 uM
*
Nodulation-Signal
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Ornithine-Decarboxylase-Inhibitor
*
P21-Inducer 10-70 uM
*
Pesticide
*
PKC-Inhibitor IC50=10 uM
*
Polyamine-Synthesis-Inhibitor
*
Progestational
*
Protein-Kinase-C-Inhibitor IC50=10-40 uM
*
PTK-Inhibitor 10-100 uM
*
Quinone-Reductase-Inducer 20 uM
Uda, Y., Price, K. R., Williamson, G., Rhodes, M. J. C. 1997. Induction of the Anticarcinogenic Marker Enzyme, Quinone Reductase, in Murine Hepatoma Cells In Vitro by Flavonoids. Cancer Lett., 120 (2): 213-216.
Radioprotective
*
Sedative 30-100 mg/kg
*
Sunscreen
*
TNF-alpha-Inhibitor IC50=3.27 uM
*
Topoisomerase-I-Inhibitor
Santti, R., Makela, S., Strauss, L., Korman, J., Kostian, M. L. 1998. Phytoestrogens: Potential Endocrine Disruptors in Males. Toxicol Ind Health, 14: 223-237.
Topoisomerase-II-Inhibitor IC45=180 uM
*
Topoisomerase-II-Inhibitor IC28=18 uM
*
Topoisomerase-II-Inhibitor 50 ug/ml
Azuma, Y., Onishi, Y., Sato, Y., Kizaki, H. 1995. Effects of Protein Tyrosine Kinase Inhibitors With Different Modes of Action on Topoisomerase Activity and Death of IL-2-Dependent CTLL-2-Cells. J Biochemistry, 118: 312-318.
Uterotrophic EC50=0.1-25 uM/l
Journal of Medicinal Food 2: 227.1999.
Vasodilator
*
VEGF-Inhibitor IC50=2-7 uM
*
Xanthine-Oxidase-Inhibitor 0.36 uM
*
|
||||||
| # Activity | Chemical Name | Part | Low PPM | High PPM | StdDev | *Reference |
|---|
| # Chemical | Activity Name | *Reference |
|---|---|---|
 |
||
*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.