|
0
|
ALKALOIDS
|
Leaf |
-- |
1400.0 |
-0.52 |
Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin. |
|
1
|
ANGUSTINE
|
Stem Bark |
-- |
-- |
-- |
Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin. |
Toxic
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
|
|
1
|
ANGUSTINE
|
Leaf |
-- |
-- |
-- |
* |
Toxic
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
|
|
0
|
ANGUSTOLINE
|
Leaf |
-- |
-- |
-- |
* |
|
77
|
CHLOROGENIC-ACID
|
Bark |
-- |
-- |
-- |
Van Ginkel, A. 1996. Identification of the Alkaloids and Flavonoids from Uncaria tomentosa Bark by TLC in Quality Control. Phytotherapy Research, 10: S18-S19. |
Aldose-Reductase-Inhibitor IC50=1.8 uM rat (strong activity)
Yoshikawa, M., et al. 1999. Medicinal Flowers. I. Aldose Reductase Inhibitors and Three New Eudesmane-Type Sesquiterpenes, Kikkanols A, B, and C, From the Flowers of Chrysanthemum inducum L. Chem Pharm Bull, 47(3): 340-345.
Anticancer (Forestomach)
*
AntiEBV
Economic & Medicinal Plant Research, 6: 189.
Antigonadotropic
Jim Duke's personal files.
Antihemolytic 10 uM
Ohnishi, M., Morishita, H., Iwahashi, H., Toda, S., Shirataki, Y., Kimura, M., and Kido, R. 1993. Inhibitory Effects of Chlorogenic Acids on Linoleic Acid Peroxidation and Haemolysis. Phytochemistry. 36(3): 579-583. 1994.
Antiherpetic
Economic & Medicinal Plant Research, 5: 194.
AntiHIV
Economic & Medicinal Plant Research, 6: 189.
Antihypercholesterolemic
Economic & Medicinal Plant Research, 6: 189.
Antiinflammatory
Hagerman, A.E. Tannin-Protein Interactions. Phenolic Compounds in Food and Their Effects on Health, Ch.19.
Antioxidant IC53=200 ppm
Huang, M-T., and Ferraro, T. Phenolic Compounds in Food and Cancer Prevention. Phenolic Compounds in Food and Their Effects on Health, Ch.2 p.21.
Antioxidant IC50=54.2 uM
*
Antiperoxidant IC50=36 uM
Planta Medica, 57: A54, 1991.
Antipolio
Jim Duke's personal files.
Antiradicular 9 x quercetin
*
Antiradicular 10 uM
Ohnishi, M., Morishita, H., Iwahashi, H., Toda, S., Shirataki, Y., Kimura, M., and Kido, R. 1993. Inhibitory Effects of Chlorogenic Acids on Linoleic Acid Peroxidation and Haemolysis. Phytochemistry. 36(3): 579-583. 1994.
Antithyroid
Jim Duke's personal files.
Antitumor
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antitumor (Forestomach)
*
Antitumor-Promoter IC25=10 uM
*
Antiulcer
Economic & Medicinal Plant Research, 6: 189.
Antiviral
Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
Cancer-Preventive
Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Cholagogue
Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
Choleretic
Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Clastogenic
Friedman, M. and Dao, L. 1990. Effect of Autoclaving and Conventional and Microwave Baking on the Ergot Alkaloid and Chlorogenic Acid Contents of Morning Glory (Ipomoea tricolor Cav. cv.) Heavenly Blue Seeds. J. Agric. Food Chem. 38: 805-808.
CNS-Active
Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
CNS-Stimulant 1/6 Caffeine
*
Fungicide
Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Hepatoprotective
Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Insectifuge
Tunon, H., Thorsell, W., and Bohlin, L. 1993. Mosquito Repelling Activity of Compounds Occurring in Achillea millefolium L. (Asteraceae). Economic Botany 48(2): 111-120, 1994.
Interferonogenic
Economic & Medicinal Plant Research, 1: 124.
Juvabional
Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Larvistat
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Lipoxygenase-Inhibitor IC23=5 mM
Oszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690.
Metal-Chelator
McEvily, A.J., Iyengar, R., and Gross, A.T. Inhibition of Polyphenol Oxidase by Phenolic Compounds. Phenolic Compounds in Food and Their Effects on Health, Ch.25.
Ornithine-Decarboxylase-Inhibitor
Hagerman, A.E. Tannin-Protein Interactions. Phenolic Compounds in Food and Their Effects on Health, Ch.19.
Oviposition-Stimulant
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Sweetener
Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
|
|
7
|
DIHYDROCORYNANTHEINE
|
Leaf |
-- |
-- |
-- |
* |
Antimalarial IC50=66 uM
Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
Antiplasmodial IC50=66 uM
Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
|
|
7
|
DIHYDROCORYNANTHEINE
|
Stem Bark |
-- |
-- |
-- |
Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin. |
Antimalarial IC50=66 uM
Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
Antiplasmodial IC50=66 uM
Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
|
|
0
|
DIHYDROKAEMPFEROL
|
Leaf |
-- |
-- |
-- |
* |
|
40
|
EPICATECHIN
|
Root |
-- |
-- |
-- |
* |
Allelochemic IC100=1 mM
Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Antiaggregant IC94=200 ug/ml
*
Antibacterial MIC=>1,000 ug/ml
*
Anticomplementary 1/2 aspirin
*
Antidiabetic 30 mg/kg rat
*
AntiEBV
Economic & Medicinal Plant Research, 6: 189.
Antihepatitic
Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
Antileukemic IC50=>10 ug/ml
*
Antioxidant 2.5 x Vit. E
*
Antioxidant IC50=6.3 ug/ml
Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990.
Antioxidant IC50=10.2 uM
*
Antioxidant 3/4 quercetin
*
Antiperoxidant
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Cancer-Preventive
Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Choline-Sparing
Singleton, V.L. 1981. Naturally Occurring Food Toxicants: Phenolic Substances of Plant Origin Common in Foods. Advances in Food Research 27: 149-217.
Hypocholesterolemic
Singleton, V.L. 1981. Naturally Occurring Food Toxicants: Phenolic Substances of Plant Origin Common in Foods. Advances in Food Research 27: 149-217.
Insulinogenic
Economic & Medicinal Plant Research, 6: 170.
Interleukin-1-alpha-Inhibitor
*
Interleukin-6-mRNA-Inhibitor
*
Lipoxygenase-Inhibitor IC50=140 uM
Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
Lipoxygenase-Inhibitor IC97=5 mM
Oszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690.
Peroxynitrite-Scavenger IC50=0.181 ug/ml
*
Xanthine-Oxidase-Inhibitor IC50=>40
*
|
|
1
|
HETEROYOHIMBINES
|
Leaf |
-- |
-- |
-- |
* |
|
|
|
3
|
HIRSUTEINE
|
Leaf |
-- |
-- |
-- |
* |
|
|
|
3
|
HIRSUTEINE
|
Stem Bark |
-- |
-- |
-- |
Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin. |
|
|
|
8
|
HIRSUTINE
|
Stem Bark |
-- |
-- |
-- |
Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin. |
Calcium-Antagonist 1 uM
*
|
|
8
|
HIRSUTINE
|
Leaf |
-- |
-- |
-- |
* |
Calcium-Antagonist 1 uM
*
|
|
15
|
INDOLE
|
Leaf |
-- |
-- |
-- |
* |
Aldose-Reductase-Inhibitor
*
Antibacterial MBC=800 ug/ml
*
Antibacterial MIC=800 ug/ml
Muroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105.
Anticariogenic MIC=800 ug/ml
Muroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105.
Antisalmonella MIC=800 ug/ml
*
Cancer-Preventive
Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Carcinogenic
Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Insectiphile
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Nematicide MLC=1 mg/ml
Shoyakugaku Zasshi, 44: 183.
Perfumery Fragrance
Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Tumorigenic
Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
|
|
3
|
ISOMITRAPHYLLINE
|
Leaf |
-- |
-- |
-- |
* |
Antileukemic IC50=45-60 uM/l
*
|
|
0
|
ISOMITRAPHYLLINE-N-OXIDE
|
Leaf |
-- |
-- |
-- |
* |
|
3
|
ISOPTEROPODINE
|
Stem Bark |
-- |
-- |
-- |
Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin. |
Antileukemic IC54=25-35 uM/l
*
|
|
15
|
ISORHYNCHOPHYLLINE
|
Stem Bark |
-- |
-- |
-- |
Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin. |
Calcium-Antagonist 10.1 uM rat
*
Neuroprotective 100-1,000 uM
*
Phagocytotic
Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin.
|
|
15
|
ISORHYNCHOPHYLLINE
|
Leaf |
-- |
-- |
-- |
* |
Calcium-Antagonist 10.1 uM rat
*
Neuroprotective 100-1,000 uM
*
Phagocytotic
Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin.
|
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