Theobroma angustifolium | Plant | Dr. Duke's Phytochemical and Ethnobotanical Databases

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Common name(s)

Castarica, Emerald Cacao

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Activities: 123

Chemicals w/Activities: 15

All Chemicals: 22

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# Activity	Chemical Name	Part Filter by plant part	Low PPM	High PPM	StdDev	^*Reference
0	ARACHIDIC-ACID	Seed	19735.0	51955.0	4.43	*
0	ASH	Seed	18200.0	44600.0	-0.10	*
1	BEHENIC-ACID	Seed	6835.0	17995.0	1.01	*
Cosmetic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
62	CAFFEINE	Petiole	80.0	82.0	-1.06	*
(+)-Inotropic Bruneton, J. 1999. Pharmacognosy, Phytochemistry, Medicinal Plants. 2nd Ed. Lavoisier Publishing, Paris. 1119 pp. Adenosine-Antagonist McKenna, D. J., Hughes, K., and Jones, K. 2000. Green Tea Monograph. Alternative Therapies, 6(3): 61-82. Analeptic 200 scu mus Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006. Analgesic-Synergist * Antiapneic Martindale's 29th Antiapoptotic * Antiasthmatic 5-10 mg/kg orl/man Martindale's 29th Anticarcinogenic * Anticariogenic * Antidermatitic Martindale's 29th Antiemetic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Antifeedant Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Antiflu Economic & Medicinal Plant Research, 5: 198. Antiherpetic * Antihypotensive 250 mg/day/orl/man Martindale's 29th Antinarcotic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Antiobesity * Antioxidant * Antirhinitic 140 mg/day/orl/man Martindale's 29th Antiserotonergic 40 ipr rat Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006. Antiserotonergic 40 scu rat Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006. Antitumor * Antitumor (Lung) * Antivaccinia * Antiviral Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart. Apoptotic * Arrhythmigenic 1,500 mg/man * cAMP-Phosphodiesterase-Inhibitor Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Cardiotonic 10-25 orl dog Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006. Cardiotonic 65-500 orl cat Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006. Catabolic Abstract (See species file) cGMP-Phosphodiesterase-Inhibitor Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Choleretic * CNS-Stimulant 100 orl mus * CNS-Stimulant 30 orl rat * Coronary-Dilator McKenna, D. J., Hughes, K., and Jones, K. 2000. Green Tea Monograph. Alternative Therapies, 6(3): 61-82. Diuretic * Energizer 20-200 mg/man * Ergotamine-Enhancer Martindale's 29th FLavor FEMA 125 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Herbicide * Hypertensive * Hypoglycemic * Insecticide Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Lypolytic Bruneton, J. 1999. Pharmacognosy, Phytochemistry, Medicinal Plants. 2nd Ed. Lavoisier Publishing, Paris. 1119 pp. Myorelaxant McKenna, D. J., Hughes, K., and Jones, K. 2000. Green Tea Monograph. Alternative Therapies, 6(3): 61-82. Neurotoxic R.J. Hixtable (Huxtable, R.J. (as T. Max). 1992. This and That:The Essential Pharmacology of Herbs and Spices. Tips 13:15-20 Huxtable, R.J. 1992b. The Myth of Benficent Nature. The Risk of Herbal Preparations. Anns. Intern. Med. 117(2):165-6; Huxtable, R. Pesticide * Phosphodiesterase-Inhibitor * Pyrogenic 60 mg/day oral hmn Daroca, P., Rodriguez, J., Reano, M., Canto, G., Miranda, P. 1996. Fever From Caffeine. Allergy, 51(3): 189-191. Pyrogenic 13.3 mg/kg ipr rbt Dascombe, M. J. 1977. Effects of Methylxanthine Drugs on Pyrogen-Induced Hyperthermia. Eur J Pharmacol, 45: 389-392. Pyrogenic 15 mg/kg ipr cat Dascombe, M. J. 1977. Effects of Methylxanthine Drugs on Pyrogen-Induced Hyperthermia. Eur J Pharmacol, 45: 389-392. Respirastimulant * Spasmogenic 1,500 mg/man * Stimulant R.J. Hixtable (Huxtable, R.J. (as T. Max). 1992. This and That:The Essential Pharmacology of Herbs and Spices. Tips 13:15-20 Huxtable, R.J. 1992b. The Myth of Benficent Nature. The Risk of Herbal Preparations. Anns. Intern. Med. 117(2):165-6; Huxtable, R. Tachycardic 1,500 mg/man * Teratogenic 14 orl rat Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006. Topoisomerase-I-Inhibitor 0.1 nM Tohda, H., Zhao, J. H., Oikawa, A. 1992. A Possible Involvement of DNA Topoisomerase I in 'Caffeine Effect' After Ultraviolet Irradiation. Tohoku J Exp Med, 168: 129-132. Topoisomerase-I-Inhibitor 75 uM Shin, C. G., Strayer, J. M., Wani, M., Snapka, R. M. 1990. Rapid Evaluation of Topoisomerase Inhibitors: Caffeine Inhibition of Topoisomerases in vivo. Teratogen Carcinogen Mutagen, 10: 41-52. Topoisomerase-II-Inhibitor 99 mM Shin, C. G., Strayer, J. M., Wani, M., Snapka, R. M. 1990. Rapid Evaluation of Topoisomerase Inhibitors: Caffeine Inhibition of Topoisomerases in vivo. Teratogen Carcinogen Mutagen, 10: 41-52. Vasodilator Bruneton, J. 1999. Pharmacognosy, Phytochemistry, Medicinal Plants. 2nd Ed. Lavoisier Publishing, Paris. 1119 pp.
62	CAFFEINE	Seed	35.0	57.0	-1.00	*
(+)-Inotropic Bruneton, J. 1999. Pharmacognosy, Phytochemistry, Medicinal Plants. 2nd Ed. Lavoisier Publishing, Paris. 1119 pp. Adenosine-Antagonist McKenna, D. J., Hughes, K., and Jones, K. 2000. Green Tea Monograph. Alternative Therapies, 6(3): 61-82. Analeptic 200 scu mus Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006. Analgesic-Synergist * Antiapneic Martindale's 29th Antiapoptotic * Antiasthmatic 5-10 mg/kg orl/man Martindale's 29th Anticarcinogenic * Anticariogenic * Antidermatitic Martindale's 29th Antiemetic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Antifeedant Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Antiflu Economic & Medicinal Plant Research, 5: 198. Antiherpetic * Antihypotensive 250 mg/day/orl/man Martindale's 29th Antinarcotic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Antiobesity * Antioxidant * Antirhinitic 140 mg/day/orl/man Martindale's 29th Antiserotonergic 40 ipr rat Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006. Antiserotonergic 40 scu rat Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006. Antitumor * Antitumor (Lung) * Antivaccinia * Antiviral Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart. Apoptotic * Arrhythmigenic 1,500 mg/man * cAMP-Phosphodiesterase-Inhibitor Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Cardiotonic 10-25 orl dog Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006. Cardiotonic 65-500 orl cat Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006. Catabolic Abstract (See species file) cGMP-Phosphodiesterase-Inhibitor Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Choleretic * CNS-Stimulant 100 orl mus * CNS-Stimulant 30 orl rat * Coronary-Dilator McKenna, D. J., Hughes, K., and Jones, K. 2000. Green Tea Monograph. Alternative Therapies, 6(3): 61-82. Diuretic * Energizer 20-200 mg/man * Ergotamine-Enhancer Martindale's 29th FLavor FEMA 125 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Herbicide * Hypertensive * Hypoglycemic * Insecticide Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Lypolytic Bruneton, J. 1999. Pharmacognosy, Phytochemistry, Medicinal Plants. 2nd Ed. Lavoisier Publishing, Paris. 1119 pp. Myorelaxant McKenna, D. J., Hughes, K., and Jones, K. 2000. Green Tea Monograph. Alternative Therapies, 6(3): 61-82. Neurotoxic R.J. Hixtable (Huxtable, R.J. (as T. Max). 1992. This and That:The Essential Pharmacology of Herbs and Spices. Tips 13:15-20 Huxtable, R.J. 1992b. The Myth of Benficent Nature. The Risk of Herbal Preparations. Anns. Intern. Med. 117(2):165-6; Huxtable, R. Pesticide * Phosphodiesterase-Inhibitor * Pyrogenic 60 mg/day oral hmn Daroca, P., Rodriguez, J., Reano, M., Canto, G., Miranda, P. 1996. Fever From Caffeine. Allergy, 51(3): 189-191. Pyrogenic 13.3 mg/kg ipr rbt Dascombe, M. J. 1977. Effects of Methylxanthine Drugs on Pyrogen-Induced Hyperthermia. Eur J Pharmacol, 45: 389-392. Pyrogenic 15 mg/kg ipr cat Dascombe, M. J. 1977. Effects of Methylxanthine Drugs on Pyrogen-Induced Hyperthermia. Eur J Pharmacol, 45: 389-392. Respirastimulant * Spasmogenic 1,500 mg/man * Stimulant R.J. Hixtable (Huxtable, R.J. (as T. Max). 1992. This and That:The Essential Pharmacology of Herbs and Spices. Tips 13:15-20 Huxtable, R.J. 1992b. The Myth of Benficent Nature. The Risk of Herbal Preparations. Anns. Intern. Med. 117(2):165-6; Huxtable, R. Tachycardic 1,500 mg/man * Teratogenic 14 orl rat Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006. Topoisomerase-I-Inhibitor 0.1 nM Tohda, H., Zhao, J. H., Oikawa, A. 1992. A Possible Involvement of DNA Topoisomerase I in 'Caffeine Effect' After Ultraviolet Irradiation. Tohoku J Exp Med, 168: 129-132. Topoisomerase-I-Inhibitor 75 uM Shin, C. G., Strayer, J. M., Wani, M., Snapka, R. M. 1990. Rapid Evaluation of Topoisomerase Inhibitors: Caffeine Inhibition of Topoisomerases in vivo. Teratogen Carcinogen Mutagen, 10: 41-52. Topoisomerase-II-Inhibitor 99 mM Shin, C. G., Strayer, J. M., Wani, M., Snapka, R. M. 1990. Rapid Evaluation of Topoisomerase Inhibitors: Caffeine Inhibition of Topoisomerases in vivo. Teratogen Carcinogen Mutagen, 10: 41-52. Vasodilator Bruneton, J. 1999. Pharmacognosy, Phytochemistry, Medicinal Plants. 2nd Ed. Lavoisier Publishing, Paris. 1119 pp.
62	CAFFEINE	Testa	38.0	52.0	-1.01	*
(+)-Inotropic Bruneton, J. 1999. Pharmacognosy, Phytochemistry, Medicinal Plants. 2nd Ed. Lavoisier Publishing, Paris. 1119 pp. Adenosine-Antagonist McKenna, D. J., Hughes, K., and Jones, K. 2000. Green Tea Monograph. Alternative Therapies, 6(3): 61-82. Analeptic 200 scu mus Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006. Analgesic-Synergist * Antiapneic Martindale's 29th Antiapoptotic * Antiasthmatic 5-10 mg/kg orl/man Martindale's 29th Anticarcinogenic * Anticariogenic * Antidermatitic Martindale's 29th Antiemetic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Antifeedant Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Antiflu Economic & Medicinal Plant Research, 5: 198. Antiherpetic * Antihypotensive 250 mg/day/orl/man Martindale's 29th Antinarcotic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Antiobesity * Antioxidant * Antirhinitic 140 mg/day/orl/man Martindale's 29th Antiserotonergic 40 ipr rat Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006. Antiserotonergic 40 scu rat Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006. Antitumor * Antitumor (Lung) * Antivaccinia * Antiviral Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart. Apoptotic * Arrhythmigenic 1,500 mg/man * cAMP-Phosphodiesterase-Inhibitor Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Cardiotonic 10-25 orl dog Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006. Cardiotonic 65-500 orl cat Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006. Catabolic Abstract (See species file) cGMP-Phosphodiesterase-Inhibitor Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Choleretic * CNS-Stimulant 100 orl mus * CNS-Stimulant 30 orl rat * Coronary-Dilator McKenna, D. J., Hughes, K., and Jones, K. 2000. Green Tea Monograph. Alternative Therapies, 6(3): 61-82. Diuretic * Energizer 20-200 mg/man * Ergotamine-Enhancer Martindale's 29th FLavor FEMA 125 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Herbicide * Hypertensive * Hypoglycemic * Insecticide Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Lypolytic Bruneton, J. 1999. Pharmacognosy, Phytochemistry, Medicinal Plants. 2nd Ed. Lavoisier Publishing, Paris. 1119 pp. Myorelaxant McKenna, D. J., Hughes, K., and Jones, K. 2000. Green Tea Monograph. Alternative Therapies, 6(3): 61-82. Neurotoxic R.J. Hixtable (Huxtable, R.J. (as T. Max). 1992. This and That:The Essential Pharmacology of Herbs and Spices. Tips 13:15-20 Huxtable, R.J. 1992b. The Myth of Benficent Nature. The Risk of Herbal Preparations. Anns. Intern. Med. 117(2):165-6; Huxtable, R. Pesticide * Phosphodiesterase-Inhibitor * Pyrogenic 60 mg/day oral hmn Daroca, P., Rodriguez, J., Reano, M., Canto, G., Miranda, P. 1996. Fever From Caffeine. Allergy, 51(3): 189-191. Pyrogenic 13.3 mg/kg ipr rbt Dascombe, M. J. 1977. Effects of Methylxanthine Drugs on Pyrogen-Induced Hyperthermia. Eur J Pharmacol, 45: 389-392. Pyrogenic 15 mg/kg ipr cat Dascombe, M. J. 1977. Effects of Methylxanthine Drugs on Pyrogen-Induced Hyperthermia. Eur J Pharmacol, 45: 389-392. Respirastimulant * Spasmogenic 1,500 mg/man * Stimulant R.J. Hixtable (Huxtable, R.J. (as T. Max). 1992. This and That:The Essential Pharmacology of Herbs and Spices. Tips 13:15-20 Huxtable, R.J. 1992b. The Myth of Benficent Nature. The Risk of Herbal Preparations. Anns. Intern. Med. 117(2):165-6; Huxtable, R. Tachycardic 1,500 mg/man * Teratogenic 14 orl rat Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006. Topoisomerase-I-Inhibitor 0.1 nM Tohda, H., Zhao, J. H., Oikawa, A. 1992. A Possible Involvement of DNA Topoisomerase I in 'Caffeine Effect' After Ultraviolet Irradiation. Tohoku J Exp Med, 168: 129-132. Topoisomerase-I-Inhibitor 75 uM Shin, C. G., Strayer, J. M., Wani, M., Snapka, R. M. 1990. Rapid Evaluation of Topoisomerase Inhibitors: Caffeine Inhibition of Topoisomerases in vivo. Teratogen Carcinogen Mutagen, 10: 41-52. Topoisomerase-II-Inhibitor 99 mM Shin, C. G., Strayer, J. M., Wani, M., Snapka, R. M. 1990. Rapid Evaluation of Topoisomerase Inhibitors: Caffeine Inhibition of Topoisomerases in vivo. Teratogen Carcinogen Mutagen, 10: 41-52. Vasodilator Bruneton, J. 1999. Pharmacognosy, Phytochemistry, Medicinal Plants. 2nd Ed. Lavoisier Publishing, Paris. 1119 pp.
0	CARBOHYDRATES	Seed	141500.0	554542.0	0.12	*
0	FAT	Seed	174800.0	460200.0	1.03	*
15	FIBER	Seed	113000.0	217000.0	0.65	*
Angiotensin-Receptor-Blocker * Antidiabetic * Antihypertensive * Antiobesity * Antitumor Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antiulcer Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Beta-Blocker * Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Cardioprotective * Diuretic * Hypocholesterolemic * Hypotensive 10 g/man/day/orl Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Hypouricemic * Laxative * Vasodilator *
27	LINOLEIC-ACID	Seed	8965.0	23600.0	-0.72	*
5-Alpha-Reductase-Inhibitor * Antiacne * Antialopecic * Antianaphylactic Economic & Medicinal Plant Research, 6: 189. Antiandrogenic * Antiarteriosclerotic * Antiarthritic Economic & Medicinal Plant Research, 6: 189. Anticoronary Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antieczemic Economic & Medicinal Plant Research, 6: 189. Antifibrinolytic Economic & Medicinal Plant Research, 1: 53. Antigranular * Antihistaminic Economic & Medicinal Plant Research, 6: 189. Antiinflammatory IC50=31 uM * Antileukotriene-D4 IC50=31 uM * Antimenorrhagic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). AntiMS Economic & Medicinal Plant Research, 6: 189. Antiprostatitic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Carcinogenic Science News, 146: 421. Comedolytic * Hepatoprotective * Hypocholesterolemic Spiller, G. A. 1996 (Spiller, G. A. Ed. 1996. CRC Handbook of Lipids in Human Nutrition. CRC Press. Boca Raton, FL. 233 pp.) Immunomodulator Economic & Medicinal Plant Research, 6: 189. Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Metastatic Science News, 146: 421. Nematicide Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp. Propecic *
18	OLEIC-ACID	Seed	86825.0	228580.0	0.90	*
5-Alpha-Reductase-Inhibitor * Allergenic * Alpha-Reductase-Inhibitor * Anemiagenic * Antialopecic * Antiandrogenic * Antiinflammatory IC50=21 uM * Antileukotriene-D4 IC50=21 uM * Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Choleretic 5 ml/man * Dermatitigenic * FLavor FEMA 1-30 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Hypocholesterolemic Spiller, G. A. 1996 (Spiller, G. A. Ed. 1996. CRC Handbook of Lipids in Human Nutrition. CRC Press. Boca Raton, FL. 233 pp.) Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Irritant Merck 11th Edition Percutaneostimulant Seki, T., Toeda, C., Kawaguchi, T., Juni, K., Sugibayashi, K., and Morimoto, Y. 1990. Enhanced Transdermal Delivery of Zidovudine in Rats and Human Skin. Chem. Pharm. Bull. 38(11): 3086-3089, 1990. Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Propecic *
13	PALMITIC-ACID	Seed	8740.0	23000.0	-0.23	*
5-Alpha-Reductase-Inhibitor * Antialopecic * Antiandrogenic * Antifibrinolytic Economic & Medicinal Plant Research, 1: 53. Antioxidant IC40=60 * FLavor FEMA 1 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Hemolytic Bisset, N.G., ed. 1994. Herbal Drugs and Phytopharmaceuticals. CRC Press. Boca Raton, FL. 566 pp. Hypercholesterolemic Spiller, G. A. 1996 (Spiller, G. A. Ed. 1996. CRC Handbook of Lipids in Human Nutrition. CRC Press. Boca Raton, FL. 233 pp.) Lubricant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Nematicide Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp. Pesticide * Propecic * Soap Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
0	PROTEIN	Seed	55500.0	105000.0	-1.15	*
8	STEARIC-ACID	Seed	43700.0	115050.0	1.93	*
5-Alpha-Reductase-Inhibitor * Cosmetic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. FLavor FEMA 2-4,000 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Hypocholesterolemic Spiller, G. A. 1996 (Spiller, G. A. Ed. 1996. CRC Handbook of Lipids in Human Nutrition. CRC Press. Boca Raton, FL. 233 pp.) Lubricant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Propecic * Suppository Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
21	THEOBROMINE	Petiole	30.0	32.0	-1.23	*
Anorexic Martindale's 28th Antiasthmatic 10 mg/kg/orl/man Martindale's 29th Anticellulitic * Arteriodilator * Bronchodilator Merck 11th Edition cAMP-Inhibitor IC50=0.06 mg/ml Schussler, M., Fricke, U., Nikolov, N., and Holzl, J. 1991. Comparison of the Flavonoids Occurring in Crataegus species and Inhibition of 3',5'-Cyclic Adenosine Monophosphate Phosphodiesterase. Plant Medica 57: Suppl Issue 2. p.A-133. cAMP-Phosphodiesterase-Inhibitor Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Cardiotonic Merck 11th Edition cGMP-Phosphodiesterase-Inhibitor Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). CNS-Stimulant * Diuretic 300-600 mg/man/day Martindale's 28th Emetic Martindale's 28th Fetotoxic 100 mg/kg * Herbicide IC41=100 ppm Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp. Myocardiotonic * Myorelaxant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Myostimulant Martindale's 29th Pesticide * Stimulant * Teratogenic 100 mg/kg * Vasodilator Merck 11th Edition
21	THEOBROMINE	Seed	330.0	368.0	-0.47	*
Anorexic Martindale's 28th Antiasthmatic 10 mg/kg/orl/man Martindale's 29th Anticellulitic * Arteriodilator * Bronchodilator Merck 11th Edition cAMP-Inhibitor IC50=0.06 mg/ml Schussler, M., Fricke, U., Nikolov, N., and Holzl, J. 1991. Comparison of the Flavonoids Occurring in Crataegus species and Inhibition of 3',5'-Cyclic Adenosine Monophosphate Phosphodiesterase. Plant Medica 57: Suppl Issue 2. p.A-133. cAMP-Phosphodiesterase-Inhibitor Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Cardiotonic Merck 11th Edition cGMP-Phosphodiesterase-Inhibitor Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). CNS-Stimulant * Diuretic 300-600 mg/man/day Martindale's 28th Emetic Martindale's 28th Fetotoxic 100 mg/kg * Herbicide IC41=100 ppm Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp. Myocardiotonic * Myorelaxant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Myostimulant Martindale's 29th Pesticide * Stimulant * Teratogenic 100 mg/kg * Vasodilator Merck 11th Edition
21	THEOBROMINE	Testa	294.0	332.0	-1.35	*
Anorexic Martindale's 28th Antiasthmatic 10 mg/kg/orl/man Martindale's 29th Anticellulitic * Arteriodilator * Bronchodilator Merck 11th Edition cAMP-Inhibitor IC50=0.06 mg/ml Schussler, M., Fricke, U., Nikolov, N., and Holzl, J. 1991. Comparison of the Flavonoids Occurring in Crataegus species and Inhibition of 3',5'-Cyclic Adenosine Monophosphate Phosphodiesterase. Plant Medica 57: Suppl Issue 2. p.A-133. cAMP-Phosphodiesterase-Inhibitor Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Cardiotonic Merck 11th Edition cGMP-Phosphodiesterase-Inhibitor Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). CNS-Stimulant * Diuretic 300-600 mg/man/day Martindale's 28th Emetic Martindale's 28th Fetotoxic 100 mg/kg * Herbicide IC41=100 ppm Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp. Myocardiotonic * Myorelaxant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Myostimulant Martindale's 29th Pesticide * Stimulant * Teratogenic 100 mg/kg * Vasodilator Merck 11th Edition
36	THEOPHYLLINE	Seed	84.0	96.0	-0.76	*
(+)-Inotropic Bruneton, J. 1999. Pharmacognosy, Phytochemistry, Medicinal Plants. 2nd Ed. Lavoisier Publishing, Paris. 1119 pp. Allergenic Martindale's 29th Antiapneic Martindale's 29th Antiasthmatic 5 mg/kg/orl/man Martindale's 29th Antibradyarrhythmic Martindale's 29th Antibronchitic * Anticellulitic * Antidote Charcoal & Propanolol Martindale's 29th Antiemphysemic Martindale's 29th Antineuralgic Martindale's 29th Antirhinitic Martindale's 29th Antispasmodic 100 uM * Antiviral * Arteriodilator * Bronchodilator * cAMP-Inhibitor IC50=0.06 mg/ml Schussler, M., Fricke, U., Nikolov, N., and Holzl, J. 1991. Comparison of the Flavonoids Occurring in Crataegus species and Inhibition of 3',5'-Cyclic Adenosine Monophosphate Phosphodiesterase. Plant Medica 57: Suppl Issue 2. p.A-133. cAMP-Phosphodiesterase-Inhibitor * Cardiovascular 30 mg/kg orl rat Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006. cGMP-Inhibitor Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). cGMP-Phosphodiesterase-Inhibitor Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Choleretic * CNS-Stimulant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Diuretic 15 mg/kg ivn rbt Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006. Fetotoxic 100 mg/kg * Herbicide IC58=100 ppm Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp. Hypertensive LAWSON in Koch, H. P. and Lawson, L. D., eds. 1996. Garlic- The Science and therapeutic application of Allium sativum L. and related species. Williams & Wilkins, Baltimore. 329 pp. Hyperuricemic Martindale's 29th Hypoglycemic * Myocardiotonic Martindale's 29th Myorelaxant 100 uM * Pesticide * Prostaglandin-Secretor 10 mg/kg orl rat Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006. Stimulant * Tachycardic Martindale's 29th Teratogenic CRC Handbook of Medicinal Herbs and/or CRC Handbook of Proximate Analyses Vasodilator *
36	THEOPHYLLINE	Testa	113.0	116.0	-1.34	*
(+)-Inotropic Bruneton, J. 1999. Pharmacognosy, Phytochemistry, Medicinal Plants. 2nd Ed. Lavoisier Publishing, Paris. 1119 pp. Allergenic Martindale's 29th Antiapneic Martindale's 29th Antiasthmatic 5 mg/kg/orl/man Martindale's 29th Antibradyarrhythmic Martindale's 29th Antibronchitic * Anticellulitic * Antidote Charcoal & Propanolol Martindale's 29th Antiemphysemic Martindale's 29th Antineuralgic Martindale's 29th Antirhinitic Martindale's 29th Antispasmodic 100 uM * Antiviral * Arteriodilator * Bronchodilator * cAMP-Inhibitor IC50=0.06 mg/ml Schussler, M., Fricke, U., Nikolov, N., and Holzl, J. 1991. Comparison of the Flavonoids Occurring in Crataegus species and Inhibition of 3',5'-Cyclic Adenosine Monophosphate Phosphodiesterase. Plant Medica 57: Suppl Issue 2. p.A-133. cAMP-Phosphodiesterase-Inhibitor * Cardiovascular 30 mg/kg orl rat Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006. cGMP-Inhibitor Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). cGMP-Phosphodiesterase-Inhibitor Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Choleretic * CNS-Stimulant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Diuretic 15 mg/kg ivn rbt Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006. Fetotoxic 100 mg/kg * Herbicide IC58=100 ppm Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp. Hypertensive LAWSON in Koch, H. P. and Lawson, L. D., eds. 1996. Garlic- The Science and therapeutic application of Allium sativum L. and related species. Williams & Wilkins, Baltimore. 329 pp. Hyperuricemic Martindale's 29th Hypoglycemic * Myocardiotonic Martindale's 29th Myorelaxant 100 uM * Pesticide * Prostaglandin-Secretor 10 mg/kg orl rat Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006. Stimulant * Tachycardic Martindale's 29th Teratogenic CRC Handbook of Medicinal Herbs and/or CRC Handbook of Proximate Analyses Vasodilator *
36	THEOPHYLLINE	Petiole	47.0	52.0	-1.31	*
(+)-Inotropic Bruneton, J. 1999. Pharmacognosy, Phytochemistry, Medicinal Plants. 2nd Ed. Lavoisier Publishing, Paris. 1119 pp. Allergenic Martindale's 29th Antiapneic Martindale's 29th Antiasthmatic 5 mg/kg/orl/man Martindale's 29th Antibradyarrhythmic Martindale's 29th Antibronchitic * Anticellulitic * Antidote Charcoal & Propanolol Martindale's 29th Antiemphysemic Martindale's 29th Antineuralgic Martindale's 29th Antirhinitic Martindale's 29th Antispasmodic 100 uM * Antiviral * Arteriodilator * Bronchodilator * cAMP-Inhibitor IC50=0.06 mg/ml Schussler, M., Fricke, U., Nikolov, N., and Holzl, J. 1991. Comparison of the Flavonoids Occurring in Crataegus species and Inhibition of 3',5'-Cyclic Adenosine Monophosphate Phosphodiesterase. Plant Medica 57: Suppl Issue 2. p.A-133. cAMP-Phosphodiesterase-Inhibitor * Cardiovascular 30 mg/kg orl rat Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006. cGMP-Inhibitor Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). cGMP-Phosphodiesterase-Inhibitor Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Choleretic * CNS-Stimulant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Diuretic 15 mg/kg ivn rbt Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006. Fetotoxic 100 mg/kg * Herbicide IC58=100 ppm Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp. Hypertensive LAWSON in Koch, H. P. and Lawson, L. D., eds. 1996. Garlic- The Science and therapeutic application of Allium sativum L. and related species. Williams & Wilkins, Baltimore. 329 pp. Hyperuricemic Martindale's 29th Hypoglycemic * Myocardiotonic Martindale's 29th Myorelaxant 100 uM * Pesticide * Prostaglandin-Secretor 10 mg/kg orl rat Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006. Stimulant * Tachycardic Martindale's 29th Teratogenic CRC Handbook of Medicinal Herbs and/or CRC Handbook of Proximate Analyses Vasodilator *

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^*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.

Plant Theobroma angustifolium (Sterculiaceae)

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