Senna occidentalis | Plant | Dr. Duke's Phytochemical and Ethnobotanical Databases

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Common name(s)

Coffee Senna

How used

Medicinal

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Activities: 357

Chemicals w/Activities: 24

All Chemicals: 53

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Exclude ubiquitous chemicals - View the list of ubiquitous chemicals

List of all chemical
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# Activity	Chemical Name	Part Filter by plant part	Low PPM	High PPM	StdDev	^*Reference
0	1,7-DIHYDROXY-5-METHOXYCARBONYL-3-METHYLXANTHONE	Plant	--	--	--	*
0	4,4',5,5'-TETRAHYDROXY-2,2'-DIMETHYL-1,1'-BIANTHRAQUINONE	Leaf	--	--	--	*
0	4-O-BETA-D-MANNOPYRANOSYL-D-MANNOPYRANOSE	Seed	--	--	--	*
0	6-O-ALPHA-D-GALACTOPYRANOSYL-D-MANNOPYRANOSE	Seed	--	--	--	*
0	ACHROSINE	Plant	--	--	--	*
24	ALOE-EMODIN	Seed	--	--	--	*
Antibacterial MIC=2-64 ug/ml * Antiherpetic * Antileukemic * Antisalmonella Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp. Antiseptic MIC=2-64 ug/ml * Antistaphylococcic MIC=2-64 ug/ml * Antitumor 1 ug/mL * Antiviral * Arylamine-N-Acetyltransferase-Inhibitor * Calcium-Antagonist (strong activity) * Candidicide MIC=25-250 ug/ml * Cathartic Merck 11th Edition Cytotoxic 20 ppm * Estrogenic * Fungicide MIC=25-250 ug/ml * Genotoxic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Laxative * Mutagenic * Pesticide * Purgative ED50=>59.6 mg/kg orl mus * Termitifuge Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Topoisomerase-II-Inhibitor 1 mM Muller, S. O., Eckert, I., Lutz, W. K., Stopper, H. 1996. Genotoxicity of the Laxative Drug Components Emodin, Aloe-emodin and Danthron in Mammalian Cells: Topoisomerase II Mediated? Mutat Res, 371: 165-173. Topoisomerase-II-Inhibitor IC50=741 uM/ml Mueller, S. O., Stopper, H. 1999. Characterization of the Genotoxicity of Anthraquinones in Mammalian Cells. Biochimica & Biophysica Acta, 1428: 406-414. Tuberculostatic Pakistan Encyclopedia Planta Medica. 1986.
0	ALPHA-3-SITOSTEROL	Plant	--	--	--	*
6	ANTHRAQUINONES	Root	--	19000.0	-0.37	*
Antilithic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Bird-Repellent Merck 11th Edition Carcinogenic * Laxative Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Litholytic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Toxic Jim Duke's personal files.
0	ANTHRONES	Root	--	45000.0	--	*
0	APIGENIN-C-GLYCOSIDE	Plant	--	--	--	*
0	BETA-SITOSTEROL-ALPHA-GLUCOSIDE	Seed	--	--	--	*
0	BIANTHRAQUINONE	Plant	--	--	--	*
28	CALCIUM	Seed	--	7450.0	0.61	*
Antiallergic 500 mg/day * Antianxiety Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antiarrhythmic 500-1,500 mg * Antiarthritic 1,000 mg/day * Antiatherosclerotic 500 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Anticlimacteric 1,000-1,500 mg/day * Antidepressant Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antidote (Aluminum) Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antidote (Lead) Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antihyperkinetic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antihypertensive * Antiinsomniac Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antimenopausal 1,000-1,500 mg/day * Antiobesity * Antiosteoporotic 500-2,000 mg/day * Antiperiodontitic 750 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. AntiPMS 1 g/day * Antirheumatic 1,000 mg/day * Antistress 500-1,500 mg/day * Antitic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Anxiolytic 500-1,500 mg/day * Calcium-Channel-Blocker * Diuretic * Hypocholesterolemic 500 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Hypotensive 1 g/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Laxative 1,000-1,200 mg * Tranquilizer 500-1,500 mg/day * Vasodilator *
2	CAMPESTEROL	Seed	--	--	--	*
Antioxidant IC37=10 uM * Hypocholesterolemic Duke, J. A. Writeups or information summaries on approximately 2,000 economic plants, USDA, ARS, Beltsville, MD 20705.
0	CASSIOLLIN	Plant	--	--	--	*
10	CHRYSAROBIN	Seed	--	2500.0	--	*
Allergenic Merck 11th Edition Antipsoriac Martindale's 29th Antitrichophytotic * Cytotoxic 1 ug/mL De Smet, P.A.G.M., Keller, K., Hansel, R. and Chandler, R.F., eds. 1993. Adverse Effects of Herbal Drugs 2. Springr-Verlag, Berlin. 348pp. Emetic * Fungicide Merck 11th Edition Irritant * Keratolytic * Mutagenic De Smet, P.A.G.M., Keller, K., Hansel, R. and Chandler, R.F., eds. 1993. Adverse Effects of Herbal Drugs 2. Springr-Verlag, Berlin. 348pp. Pesticide *
10	CHRYSOPHANOL	Leaf	--	--	--	*
Antibacterial Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155. Antiseptic * Calcium-Antagonist 5/6 aloeemodin * Candidicide Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155. Cathartic * Hemostat * Pesticide * Pigment Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Purgative ED50=>500 mg/kg orl mus * Termitifuge Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
10	CHRYSOPHANOL	Root	--	--	--	*
Antibacterial Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155. Antiseptic * Calcium-Antagonist 5/6 aloeemodin * Candidicide Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155. Cathartic * Hemostat * Pesticide * Pigment Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Purgative ED50=>500 mg/kg orl mus * Termitifuge Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
12	COPPER	Seed	--	15.0	0.02	*
Antianemic * Antiarthritic * Antidiabetic 2-4 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antifatigue * Antiinflammatory Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antinociceptive Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antiosteoporotic * Cardioprotective * Contraceptive Martindale's 28th Hypocholesterolemic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Immunomodulator * Schizophrenigenic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
58	EMODIN	Root	--	--	--	*
AGEs-Inhibitor IC50=118 uM * Aldose-Reductase-Inhibitor IC50=15.9 uM * Allergenic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp. Antiaggregant * Antiangiogenic * Antibacterial * Anticytomegalovirus ED50=1.1 ug/ml * Antifeedant Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Antiinflammatory 15 mg/kg * Antileukemic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antilymphomic * AntiMRSA MIC 2-64 ug/ml * Antimutagenic * Antineoplastic * Antiplaque ED50=1.1 ug/ml * Antiproliferant IC50=20-30 uM * Antisarcomic * Antiseptic * Antispasmodic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Antisprout * Antitumor (Breast) * Antiulcer 15 mg/kg * Antivaginitic TIllotson, A. K. (with Abel, Jr., R., Tillotson, N.H., Bajracharya, V.M.B.). 2001. The One Earth Herbal Sourcebook: Everything You Need to Know about Chinese, Western, and Ayurvedic Herbal Treatments. Twin Streams, Kensington Publishing Corp. NY,NY. 596 pp Antiviral ED50=1.1 ug/ml * Antiviral EC50=1.1 * Cathartic Merck 11th Edition CNS-Depressant 15 mg/kg ipr mus * Collagenase-Inhibitor IC50=40 uM * COX-2-Inhibitor * Cytotoxic CD50=2.6 ug/ml * Differentiator IC50=20-30 uM * Estrogenic * Genotoxic * Gonadotropic * Hypolipidemic * Immunostimulant * Immunosuppressant * iNOS-Inhibitor * Leucocytogenic * MMP-2-Inhibitor * MMP-7-Inhibitor * MMP-9-Inhibitor * Mutagenic * NO-Inhibitor IC50=60.7 uM * Pesticide * PGE2-Inhibitor * Prostaglandin-Synthesis-Inhibitor IC50=23 uM/ml Mueller, S. O., Stopper, H. 1999. Characterization of the Genotoxicity of Anthraquinones in Mammalian Cells. Biochimica & Biophysica Acta, 1428: 406-414. Protein-Kinase-C-Inhibitor IC50=25 uM * PTK-Inhibitor IC50=19-37 uM * PTK-Inhibitor 10-100 uM * Purgative ED50=>500 mg/kg orl mus * Styptic * Topoisomerase-II-Inhibitor 1 mM Muller, S. O., Eckert, I., Lutz, W. K., Stopper, H. 1996. Genotoxicity of the Laxative Drug Components Emodin, Aloe-emodin and Danthron in Mammalian Cells: Topoisomerase II Mediated? Mutat Res, 371: 165-173. Topoisomerase-II-Inhibitor IC50=7 uM/ml Mueller, S. O., Stopper, H. 1999. Characterization of the Genotoxicity of Anthraquinones in Mammalian Cells. Biochimica & Biophysica Acta, 1428: 406-414. Trichomonicide * Tyrosine-Kinase-Inhibitor * Vasodilator * Vasorelaxant *

List of all activity chemical
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# Activity	Chemical Name	Part Filter by plant part	Low PPM	High PPM	StdDev	^*Reference

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^*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.

Plant Senna occidentalis (Fabaceae)

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