0
|
1,1,3-TRIMETHYL-P-3-PHENYLINDAN
|
Essential Oil |
-- |
-- |
-- |
* |
0
|
1-METHYL-2-ETHYL-BENZENE
|
Essential Oil |
-- |
-- |
-- |
* |
0
|
1-METHYL-3-ETHYL-BENZENE
|
Essential Oil |
-- |
-- |
-- |
* |
0
|
1-METHYL-4-ETHYL-BENZENE
|
Essential Oil |
-- |
-- |
-- |
* |
0
|
2,4-DIMETHYL-HEPTA-2,4-DIENAL
|
Essential Oil |
-- |
-- |
-- |
* |
0
|
2-PHENYLETHANOL
|
Essential Oil |
-- |
-- |
-- |
* |
0
|
2-PHENYLETHANOL
|
Leaf Essent. Oil |
-- |
-- |
-- |
* |
0
|
3,5-DIMETHYL-METHYLBENZOATE
|
Essential Oil |
-- |
-- |
-- |
* |
0
|
ACETYL-NAPHTHALENE
|
Essential Oil |
-- |
-- |
-- |
* |
10
|
ALPHA-AMYRIN
|
Root |
-- |
600.0 |
-- |
* |
Antiedemic IC43=40 mg/kg ipr rat
*
Antiinflammatory IC71=1,000 ppm orl
*
|
7
|
ASTRAGALIN
|
Leaf |
-- |
-- |
-- |
* |
ACE-Inhibitor ID50=180 ug/ml rat (24 hr.)
*
Aldose-Reductase-Inhibitor IC30=1 uM
*
Aldose-Reductase-Inhibitor IC62=10 uM
Shimizu, M., Ito, T., Terashima, S., Hayashi, T., Arisawa, M., Morita, N., Kurokawa, S., Ito, K., and Hashimoto, Y. 1984. Inhibition of Lens Aldose Reductase by Flavonoids. Phytochemistry, 23: 1885-1888.
Hypotensive
Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990.
|
0
|
BENZOTHIAZOLE
|
Essential Oil |
-- |
-- |
-- |
* |
9
|
BENZYL-ALCOHOL
|
Essential Oil |
-- |
-- |
-- |
* |
Allergenic
Martindale's 29th
Anesthetic
Martindale's 28th
Antiodontalgic
Martindale's 28th
Antiseptic
Martindale's 29th
FLavor Fema 200-1,200
Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Sedative
Jim Duke's personal files.
|
13
|
BETA-PINENE
|
Essential Oil |
-- |
-- |
-- |
* |
Antiseptic
Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
FLavor FEMA 15-600
Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Herbicide
Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Insectifuge
Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Irritant
Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Perfumery
Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Spasmogenic
Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
|
47
|
BETA-SITOSTEROL
|
Root |
-- |
50.0 |
-0.27 |
* |
Anorexic
Martindale's 28th
Antiadenomic
Merck 11th Edition
Antiandrogenic
Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antibacterial
Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155.
Anticancer (Breast)
Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103.
Antiedemic IC54=320 mg/kg orl
*
Antiestrogenic
Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antifeedant
Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Antifertility
Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antigonadotrophic
Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antihyperlipoproteinaemic
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antimutagenic 250 ug/ml
*
Antiophidic 2.3 mg mus
Economic & Medicinal Plant Research, 5: 363.
Antiprogestational
Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antiprostaglandin 30 mg/day/12 wks
*
Antiprostatadenomic
Merck 11th Edition
Antiprostatitic 10-20 mg 3 x/day/orl man
*
Antipyretic
Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
Antitumor (Breast)
Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103.
Antiviral
Abid Ali Khan, M.M., Jain, D.C., Bhakuni, R.S., Zaim, M., and Thakur, R.S. 1991. Occurrence of some antiviral sterols in Artemisia annua. Plant Science, 75: 161-165, 1991.
Artemicide LC50=110 ppm
Jung, J.H., Pummangura, S., Chaichantipyuth, c., Patarapanich, C., and McLaughlin, J.L. 1989. Bioactive Constituents of Melodorum fruticosum. Phytochemistry. 29(5): 1667-1670. 1990.
Cancer-Preventive
Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidicide
Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155.
Febrifuge
Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
Gonadotrophic
Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Hypocholesterolemic 2-6 g/man/day/orl
Martindale's 30th
Hypocholesterolemic 9-3,330 mg/man/day/orl
Martindale's 28th
Hypoglycemic
Ivorra, M.D., Paya, M., and Villar, A. 1989. A Review of Natural Products and Plants as Potential Antidiabetic Drugs. Journal of Ethnopharmacology, 27: 243-275, 1989.
Hypolipidemic 2-6 g/day
*
Spermicide
Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Ubiquiot
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Ulcerogenic 500 mg/kg ipr rat
*
|
13
|
BETULIN
|
Root |
-- |
-- |
-- |
* |
Antiinflammatory
Recio, M., et al. 1994. Investigations on the Steroidal Anti-Inflammatory Activity of Triterpenoids from Diospyros leucomelas*. Planta Medica, 61: 9.
Antitumor
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Aphidifuge
Lugemwa, F.N., Huang, F-Y., Bentley, M.D., Mendel, M.J., and Alford, A.R. 1990. A Heliothis zea Antifeedant from the Abundant Birchbark Triterpene Betulin. J. Agric. Food Chem. 38(2): 493-494.
Prostaglandin-Synthesis-Inhibitor IC50=119 uM
Huang, C., Tunon, H., Bohlin, L. 1995. Anti-Inflammatory Compounds Isolated from Menyanthes trifoliata L. Yao Hsueh Hsueh Pao, 30(8): 621-626.
Topoisomerase-II-Inhibitor IC50=38.6 uM
*
|
13
|
BETULIN
|
Shoot |
-- |
-- |
-- |
* |
Antiinflammatory
Recio, M., et al. 1994. Investigations on the Steroidal Anti-Inflammatory Activity of Triterpenoids from Diospyros leucomelas*. Planta Medica, 61: 9.
Antitumor
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Aphidifuge
Lugemwa, F.N., Huang, F-Y., Bentley, M.D., Mendel, M.J., and Alford, A.R. 1990. A Heliothis zea Antifeedant from the Abundant Birchbark Triterpene Betulin. J. Agric. Food Chem. 38(2): 493-494.
Prostaglandin-Synthesis-Inhibitor IC50=119 uM
Huang, C., Tunon, H., Bohlin, L. 1995. Anti-Inflammatory Compounds Isolated from Menyanthes trifoliata L. Yao Hsueh Hsueh Pao, 30(8): 621-626.
Topoisomerase-II-Inhibitor IC50=38.6 uM
*
|
0
|
BETULINALDEHYDE
|
Shoot |
-- |
-- |
-- |
* |
22
|
BETULINIC-ACID
|
Leaf |
-- |
-- |
-- |
Duke, J. A. Writeups or information summaries on approximately 2,000 economic plants, USDA, ARS, Beltsville, MD 20705. |
Anticancer
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Anticarcinomic
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
AntiHIV EC50=2.0 ug/ml
Kashiwada, Y., et. al. 1998. Anti-AIDS Agents. 30. Anti-HIV Activity of Oleanolic Acid, Pomolic Acid, and Structurally Related Triterpenoids. J. Nat. Prod., 61 (9): 1090-1095.
Antiinflammatory
Recio, M., et al. 1994. Investigations on the Steroidal Anti-Inflammatory Activity of Triterpenoids from Diospyros leucomelas*. Planta Medica, 61: 9.
Antimalarial IC50=19-26 ug/ml
*
Antimelanomic
New York Times, 3/28/95.
Antiplasmodial IC50=19-26 ug/ml
*
Antitumor
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Cytotoxic 50-100 ppm
Biosyn. Prod. Cancer Chemotherapy (Petit et al)
Phospholipase-A2-Inhibitor
*
Prostaglandin-Synthesis-Inhibitor IC50=101 uM
Huang, C., Tunon, H., Bohlin, L. 1995. Anti-Inflammatory Compounds Isolated from Menyanthes trifoliata L. Yao Hsueh Hsueh Pao, 30(8): 621-626.
Prostaglandin-Synthesis-Inhibitor 200 ug/ml
Dunstan, C. A., Liu, B., Welch, C. J., Perera, P., Bohlin, L. 1998. Alphitol, a Phenolic Substance from Alphitonia zizyphoides which Inhibits Prostaglandin Biosynthesis in vitro. Phytochemistry, 48(3): 495-497.
|
22
|
BETULINIC-ACID
|
Root |
-- |
-- |
-- |
* |
Anticancer
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Anticarcinomic
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
AntiHIV EC50=2.0 ug/ml
Kashiwada, Y., et. al. 1998. Anti-AIDS Agents. 30. Anti-HIV Activity of Oleanolic Acid, Pomolic Acid, and Structurally Related Triterpenoids. J. Nat. Prod., 61 (9): 1090-1095.
Antiinflammatory
Recio, M., et al. 1994. Investigations on the Steroidal Anti-Inflammatory Activity of Triterpenoids from Diospyros leucomelas*. Planta Medica, 61: 9.
Antimalarial IC50=19-26 ug/ml
*
Antimelanomic
New York Times, 3/28/95.
Antiplasmodial IC50=19-26 ug/ml
*
Antitumor
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Cytotoxic 50-100 ppm
Biosyn. Prod. Cancer Chemotherapy (Petit et al)
Phospholipase-A2-Inhibitor
*
Prostaglandin-Synthesis-Inhibitor IC50=101 uM
Huang, C., Tunon, H., Bohlin, L. 1995. Anti-Inflammatory Compounds Isolated from Menyanthes trifoliata L. Yao Hsueh Hsueh Pao, 30(8): 621-626.
Prostaglandin-Synthesis-Inhibitor 200 ug/ml
Dunstan, C. A., Liu, B., Welch, C. J., Perera, P., Bohlin, L. 1998. Alphitol, a Phenolic Substance from Alphitonia zizyphoides which Inhibits Prostaglandin Biosynthesis in vitro. Phytochemistry, 48(3): 495-497.
|