Melissa officinalis | Plant | Dr. Duke's Phytochemical and Ethnobotanical Databases

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Common name(s)

Balm, Bee Balm, Lemonbalm, Melissa

How used

GRAS

Data Views

Activities: 368

Chemicals w/Activities: 55

All Chemicals: 125

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Exclude ubiquitous chemicals - View the list of ubiquitous chemicals

List of all chemical
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# Activity	Chemical Name	Part Filter by plant part	Low PPM	High PPM	StdDev	^*Reference
0	(+)-CITRONELLAL	Shoot	2.0	975.0	--	*
0	1,2-HUMULENE-EPOXIDE	Shoot	--	0.1	--	Deutsche Apot. Ziit. 129(4):155-163. W. Schulze et al. Die Melisse.
0	1-OCTEN-3-OL	Shoot	0.0	50.0	-0.42	*
0	10-(ALPHA)-CADINOL	Plant	1.0	8.0	-1.00	*
0	2-PHENYLETHANOL	Tissue Culture	--	--	--	Gbolade, A.A. and Lockwood, G.B. 1991. The Constituents of Melissa officinalis L. Cultures. J. Ess. Oil Res., 3: 111-114.
0	2Z,4E,6E-ALLOFARNESENE	Shoot	--	0.1	--	Deutsche Apot. Ziit. 129(4):155-163. W. Schulze et al. Die Melisse.
2	3-OCTANOL	Shoot	0.0	8.0	-0.29	*
FLavor FEMA Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
0	3-OCTANONE	Shoot	1.0	15.0	-0.24	Deutsche Apot. Ziit. 129(4):155-163. W. Schulze et al. Die Melisse.
0	3E,6E-ALPHA-FARNESENE	Shoot	5.0	40.0	--	Deutsche Apot. Ziit. 129(4):155-163. W. Schulze et al. Die Melisse.
0	6-METHYL-5-HEPTEN-2-ONE	Shoot	3.0	24.0	2.40	Deutsche Apot. Ziit. 129(4):155-163. W. Schulze et al. Die Melisse.
0	ALPHA-CADINENE	Shoot	--	0.1	-0.50	Deutsche Apot. Ziit. 129(4):155-163. W. Schulze et al. Die Melisse.
3	ALPHA-CADINOL	Shoot	1.0	120.0	1.51	Deutsche Apot. Ziit. 129(4):155-163. W. Schulze et al. Die Melisse.
Acaricide * Antimite * Pesticide *
0	ALPHA-COPAENE	Shoot	2.0	120.0	1.03	*
0	ALPHA-CUBEBENE	Shoot	0.1	38.0	0.44	*
2	ALPHA-HUMULENE	Shoot	1.0	80.0	0.35	*
Antitumor Zheng, G-Q., Kenney, P.M., and Lam, L.K.T. Sesquiterpenes From Clove (Eugenia caryophyllata) As Potential Anticarcinogenic Agents. Journal of Natural Products 55(7): 999-1003, 1992. Perfumery Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
0	ALPHA-MUUROLENE	Shoot	3.0	24.0	-0.07	Deutsche Apot. Ziit. 129(4):155-163. W. Schulze et al. Die Melisse.
23	ALPHA-TERPINEOL	Shoot	--	--	--	*
ACE-Inhibitor 100 ug/ml (weak activity) * Aldose-Reductase-Inhibitor 100 ug/ml Okamura, K., Iwakami, S., Matsunaga, T. 1992. Biological Activity of Monoterpenes from Trees. Toyama-Ken Yakuji Kenkyusho Nenpo, (20): 95-101. Allelopathic Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands. Antiacne * Antibacterial MIC=800-1,600 ug/ml Muroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105. Anticancer Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY. Anticariogenic MIC=800-1,600 ug/ml Muroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105. Antiinflammatory * Antiproliferant * Antiseptic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Cicatrizant ED50=240 ug/g mus * FLavor FEMA 5-40 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Insecticide 1.29 uM/fly * Interleukin-6-Inhibitor * Mosquitofuge > Deet * Motor-Depressant Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC Nematicide MLC=1 mg/ml Shoyakugaku Zasshi, 44: 183. Perfumery Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Pesticide * Sedative Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC Termiticide IC100=5 mg/g * Transdermal * Vulnerary ED50=240 ug/g mus *
0	ANETHOL	Shoot	--	--	--	*
0	APIGENIN-7-O-BETA-D-GLUCOSIDE	Shoot	--	--	--	*
24	BENZALDEHYDE	Tissue Culture	--	--	--	Gbolade, A.A. and Lockwood, G.B. 1991. The Constituents of Melissa officinalis L. Cultures. J. Ess. Oil Res., 3: 111-114.
Allergenic * Anesthetic * Antibacterial * Anticancer * Antimutagenic * Antipeptic * Antiseptic * Antispasmodic * Antitumor * Candidicide * FLavor FEMA 150-800 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Immunostimulant * Insecticide Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. Insectifuge 50 ppm J. Stored. Prod. Res., 22:141, 1986. Motor-Depressant Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC Narcotic Merck 11th Edition Nematicide MLC=1 mg/ml Shoyakugaku Zasshi, 44: 183. Pesticide * Sedative Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC Termiticide LD100=5 mg/g * Tyrosinase-Inhibitor ID50=830 uM * Tyrosinase-Inhibitor ID50=820 uM * Tyrosinase-Inhibitor ID50=87 ug/ml * Tyrosinase-Inhibitor ID50=0.82 mM *

List of all activity chemical
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# Activity	Chemical Name	Part Filter by plant part	Low PPM	High PPM	StdDev	^*Reference

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^*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.

Plant Melissa officinalis (Lamiaceae)

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