0
|
2-PIPEONYLIDENE-2-VERYTRYL-3-R-GAMMA-BUTYROLACTONE
|
Seed |
-- |
-- |
-- |
* |
101
|
APIGENIN
|
Leaf |
-- |
-- |
-- |
* |
Antiaflatoxin IC50=9.52 uM
*
Antiaflatoxin IC50=2.57 ppm
*
Antiallergic
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antibacterial
Recio, M. C., Rios, J. L., and Villar, A., A review of some antimicrobial compounds isolated from medicinal plants reported in the literature 1978-1988, Phytotherapy Research, 3(4), 1989, 117-125.
Antidermatitic
Bisset, N.G., ed. 1994. Herbal Drugs and Phytopharmaceuticals. CRC Press. Boca Raton, FL. 566 pp.
Antiestrogenic
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiherpetic 20-54 ug/ml
*
Antihistaminic IC50=10-35 uM
*
Antiinflammatory #NAME?
*
Antiinflammatory IC~65=1,000 uM
*
Antimutagenic ID50=10-40 nM
Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
Antimutagenic ID50=0.55 ug/ml
*
Antioxidant 1.5 x Vit. E
*
Antioxidant IC28.5=62.5 ug/ml
*
Antiproliferant 1-50 uM
*
Antiproliferant IC50=155 uM
*
Antispasmodic EC50=1-5 uM
*
Antithyroid
Jim Duke's personal files.
Antitumor (Breast) 1-50 uM
*
Aromatase-Inhibitor IC65=1 uM/l
Journal of Medicinal Food 2: 235.1999.
Beta-Glucuronidase-Inhibitor IC50=~40 uM
*
Calcium-Antagonist?
Biochimica & Biophysica Acta, 1115: 69, 1991.
Cancer-Preventive
Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
COX-1-Inhibitor IC65=1,000 uM
*
COX-2-Inhibitor IC50=<15 uM
*
COX-2-Inhibitor IC>65=1,000 uM
*
Cyclooxygenase-Inhibitor
*
Cytochrome-P450-1A1-Inhibitor
*
Cytotoxic IC88=10 ug/ml
Planta Medica, 57: A113, 1991.
Deiodinase-Inhibitor
Jim Duke's personal files.
Differentiator MIC=30 uM
*
Differentiator IC40=40 uM
*
Diuretic
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Estrogenic 16% genistein
*
Estrogenic EC50=0.1-25 uM/l
Journal of Medicinal Food 2: 227.1999.
Hyaluronidase-Inhibitor IC50+=50-250 uM
*
Hypotensive
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
iNOS-Inhibitor IC50=<15 uM
*
Interleukin-6-Inhibitor
*
Musculotropic
Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
Myorelaxant
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
NO-Synthase-Inhibitor 5-50 uM
*
Nodulation-Signal
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Ornithine-Decarboxylase-Inhibitor
*
PKC-Inhibitor IC50=10 uM
*
Polyamine-Synthesis-Inhibitor
*
Protein-Kinase-C-Inhibitor IC50=10-40 uM
*
PTK-Inhibitor 10-100 uM
*
Quinone-Reductase-Inducer 20 uM
Uda, Y., Price, K. R., Williamson, G., Rhodes, M. J. C. 1997. Induction of the Anticarcinogenic Marker Enzyme, Quinone Reductase, in Murine Hepatoma Cells In Vitro by Flavonoids. Cancer Lett., 120 (2): 213-216.
TNF-alpha-Inhibitor IC50=3.27 uM
*
Topoisomerase-I-Inhibitor
Santti, R., Makela, S., Strauss, L., Korman, J., Kostian, M. L. 1998. Phytoestrogens: Potential Endocrine Disruptors in Males. Toxicol Ind Health, 14: 223-237.
Topoisomerase-II-Inhibitor IC28=18 uM
*
Topoisomerase-II-Inhibitor IC45=180 uM
*
Topoisomerase-II-Inhibitor 50 ug/ml
Azuma, Y., Onishi, Y., Sato, Y., Kizaki, H. 1995. Effects of Protein Tyrosine Kinase Inhibitors With Different Modes of Action on Topoisomerase Activity and Death of IL-2-Dependent CTLL-2-Cells. J Biochemistry, 118: 312-318.
Uterotrophic EC50=0.1-25 uM/l
Journal of Medicinal Food 2: 227.1999.
VEGF-Inhibitor IC50=2-7 uM
*
Xanthine-Oxidase-Inhibitor 0.36 uM
*
|
47
|
BETA-SITOSTEROL
|
Plant |
-- |
-- |
-- |
* |
Anorexic
Martindale's 28th
Antiadenomic
Merck 11th Edition
Antiandrogenic
Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antibacterial
Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155.
Anticancer (Breast)
Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103.
Antiedemic IC54=320 mg/kg orl
*
Antiestrogenic
Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antifeedant
Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Antifertility
Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antigonadotrophic
Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antihyperlipoproteinaemic
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antimutagenic 250 ug/ml
*
Antiophidic 2.3 mg mus
Economic & Medicinal Plant Research, 5: 363.
Antiprogestational
Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antiprostaglandin 30 mg/day/12 wks
*
Antiprostatadenomic
Merck 11th Edition
Antiprostatitic 10-20 mg 3 x/day/orl man
*
Antipyretic
Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
Antitumor (Breast)
Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103.
Antiviral
Abid Ali Khan, M.M., Jain, D.C., Bhakuni, R.S., Zaim, M., and Thakur, R.S. 1991. Occurrence of some antiviral sterols in Artemisia annua. Plant Science, 75: 161-165, 1991.
Artemicide LC50=110 ppm
Jung, J.H., Pummangura, S., Chaichantipyuth, c., Patarapanich, C., and McLaughlin, J.L. 1989. Bioactive Constituents of Melodorum fruticosum. Phytochemistry. 29(5): 1667-1670. 1990.
Cancer-Preventive
Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidicide
Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155.
Febrifuge
Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
Gonadotrophic
Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Hypocholesterolemic 2-6 g/man/day/orl
Martindale's 30th
Hypocholesterolemic 9-3,330 mg/man/day/orl
Martindale's 28th
Hypoglycemic
Ivorra, M.D., Paya, M., and Villar, A. 1989. A Review of Natural Products and Plants as Potential Antidiabetic Drugs. Journal of Ethnopharmacology, 27: 243-275, 1989.
Hypolipidemic 2-6 g/day
*
Spermicide
Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Ubiquiot
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Ulcerogenic 500 mg/kg ipr rat
*
|
0
|
CURCIN
|
Seed |
-- |
-- |
-- |
* |
0
|
GADAIN
|
Plant |
-- |
-- |
-- |
* |
18
|
HISTAMINE
|
Leaf |
-- |
-- |
-- |
* |
Antichilblain
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
AntiMeniere's
Martindale's 28th
Antimigraine
Martindale's 28th
Bronchoconstrictor
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Bronchostimulant
Martindale's 28th
Cardiovascular 0.15 mg/kg ivn rbt
Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
Gastrostimulant
Martindale's 28th
Histaminic Antidote:Adrenaline
Martindale's 29th
Hypotensive
Martindale's 28th
Irritant
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Myostimulant
Martindale's 29th
Radioprotective
Martindale's 28th
Secretogogue
Martindale's 29th
Tachycardic
Martindale's 29th
Ulcerogenic 100 mg/kg ipr rat
*
Vasodilator
Martindale's 29th
|
0
|
ISOPHYTOSTEROL
|
Bark |
-- |
3500.0 |
-- |
* |
4
|
ISOVITEXIN
|
Leaf |
-- |
-- |
-- |
* |
ACE-Inhibitor IC50=0.28 mM/l
*
Antioxidant >BHA
Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Cancer-Preventive
Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
|
0
|
JATROPHINE
|
Bark |
-- |
4000.0 |
-- |
* |
1
|
JATROPHOLONES
|
Plant |
-- |
-- |
-- |
* |
Antitumor
Grenand, P., Moretti, C., and Jacquemin, H. 1987. Pharmacopees Traditionnelles en Guyane. l'ORSTROM, Paris. 569 pp.
|
2
|
JATROPHONE
|
Root |
-- |
-- |
-- |
* |
Antitumor
Wagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
Cytotoxic 0.17
Biosyn. Prod. Cancer Chemotherapy (Petit et al)
|
35
|
TANNIN
|
Leaf |
-- |
-- |
-- |
* |
Antinephritic
Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990.
Antiophidic
Economic & Medicinal Plant Research, 5: 363.
Antioxidant 1/3 quercetin
*
Antioxidant IC50=1.44 ug/ml
*
Antiradicular 500 mg/kg/day orl mus
Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990.
Antiradicular 1/3 quercetin
*
Antirenitic
Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990.
Cancer-Preventive
HerbalGram No. 22 - Spring 1990, page 14.
Cyclooxygenase-Inhibitor
*
Glucosyl-Transferase-Inhibitor
*
Ornithine-Decarboxylase-Inhibitor
*
Psychotropic
Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990.
Xanthine-Oxidase-Inhibitor
*
|
18
|
VITEXIN
|
Leaf |
-- |
-- |
-- |
* |
ACE-Inhibitor IC50=0.3 mM/l
*
Aldose-Reductase-Inhibitor IC15=10 uM
Shimizu, M., Ito, T., Terashima, S., Hayashi, T., Arisawa, M., Morita, N., Kurokawa, S., Ito, K., and Hashimoto, Y. 1984. Inhibition of Lens Aldose Reductase by Flavonoids. Phytochemistry, 23: 1885-1888.
Aldose-Reductase-Inhibitor 5 ug/ml
Okamot, Y., Yoshizawa, T. 1994. Angiotensin-Converting Enzyme Inhibitors and Aldose Reductase Inhibitors Containing Passiflora quadraqularis Extracts or Vitexin. Patent, Japan Kokai Tokkyo Koho-06,293,657. 4pp.
Antiarrhythmic
Jim Duke's personal files.
Antibradiquinic
Fitoterapia No.61: 277, 1990.
Antiinflammatory
Fitoterapia No.61: 263, 1990.
Antithyroid
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
cAMP-Phosphodiesterase-Inhibitor IC50=1.6 mg/ml
Schussler, M., Fricke, U., Nikolov, N., and Holzl, J. 1991. Comparison of the Flavonoids Occurring in Crataegus species and Inhibition of 3',5'-Cyclic Adenosine Monophosphate Phosphodiesterase. Plant Medica 57: Suppl Issue 2. p.A-133.
Cancer-Preventive
Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Goitrogenic
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Thyroid-Peroxidase-Inhibitor
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
|