Galium odoratum | Plant | Dr. Duke's Phytochemical and Ethnobotanical Databases

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Common name(s)

Waldmeister, Woodruff

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Medicinal

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Activities: 147

Chemicals w/Activities: 9

All Chemicals: 14

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# Activity	Chemical Name	Part	Low PPM	High PPM	StdDev	^*Reference
0	ANTHRACENE-DERIVATIVES	Plant	--	--	--	*
6	ANTHRAQUINONES	Plant	--	--	--	*
Antilithic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Bird-Repellent Merck 11th Edition Carcinogenic * Laxative Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Litholytic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Toxic Jim Duke's personal files.
9	ASPERULOSIDE	Plant	--	500.0	--	*
Anticlastogen * Antiinflammatory Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. Antimutagenic * Antineoplastic Medicinal and Poisonous Plants of the Tropics. Leeuwenberg, A.J.M., ed. Pudoc, Wageningen. 1987. Cathartic ED50=240 mg/kg Wagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176) Herbicide Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Hypotensive List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979. Laxative Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Pesticide *
23	CITRIC-ACID	Plant	--	--	--	*
Allergenic * Alpha-Amylase-Inhibitor * Antiaphthic 20,000 ppm Martindale's 28th Antiatherosclerotic * Antibacterial * Anticalculic * Anticoagulant Merck 11th Edition Antileishmanic * Antimutagenic Economic & Medicinal Plant Research, 6: 235. Antioxidant Synergist Merck 11th Edition Antiseborrheic * Antiseptic Martindale's 29th Antitubercular * Antitumor Economic & Medicinal Plant Research, 6: 235. Disinfectant Martindale's 29th FLavor FEMA 370-4,400 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Hemostat * Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253. Laxative? Lawrence Review of Natural Products, Sep-91. Litholytic Martindale's 29th Mycobactericide * Odontolytic Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253. Refrigerant Martindale's 28th
57	COUMARIN	Plant	7000.0	13000.0	2.41	*
Aldose-Reductase-Inhibitor 10 ug/ml cow (weak activity, 11% inhibition) Okada,Y,et al.1995.Search for Naturally Occurring Substances to Prevent the Complications of Diabetes.II.Inhibitory Effect of Coumarin and Flavonoid Derivatives on Bovine Lens Aldose Reductase and Rabbit Platelet Aggregation.Chem Pharm Bull43(8):1385-1387 Allelochemic IC100=2 mM Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp. Analgesic Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253. Anesthetic * Antiaggregant * Antiandrogenic Planta Medica, 56(6): 671, 1990. Antibrucellosic Gawron, A., Gorski, G., Glowniak, K. 1989. Increased proliferation of phytohaemagglutinin (PHA)-stimulated human leucocytes after 8-methoxypsoralen treatment. J. Pharm. Pharmacol. 42: 194-195, 1990. Anticancer (Kidney) 400-7,000 mg/day Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Anticancer (Prostate) 400-7,000 mg/day Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Antidiuretic Antiedemic Shimizu,M., et al. 1990. Anti-inflammatory Constituents of Topically Applied Crude Drugs. IV.1) Constituents and Anti-inflammatory Effect of Paraguayan Crude Drug 'Alhucema' (Lavandula latifolia Vill.)2). Chem. Pharm. Bull. 38(8): 2283-2284, 1990. Antiesherichic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antiinflammatory Shimizu,M., et al. 1990. Anti-inflammatory Constituents of Topically Applied Crude Drugs. IV.1) Constituents and Anti-inflammatory Effect of Paraguayan Crude Drug 'Alhucema' (Lavandula latifolia Vill.)2). Chem. Pharm. Bull. 38(8): 2283-2284, 1990. Antilymphedemic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Antimelanomic 50 mg/day * Antimetastatic 50 mg/man/day Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Antimitotic Pandeya, S.N. 1970. Biological Activity of Adamantyl Derivatives. The Indian Journal of Pharmacy, 33: 7. Antimononuccleotic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Antimutagenic Economic & Medicinal Plant Research, 6: 235. Antimycoplasmotic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Antipsittacotic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Antipsoriac Pandeya, S.N. 1970. Biological Activity of Adamantyl Derivatives. The Indian Journal of Pharmacy, 33: 7. Antitoxoplasmotic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Antitumor 50 mg/day * Antitumor (GI) * Antitumor (Kidney) 400-7,000 mg/day Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Antitumor (Prostate) 400-7,000 mg/day Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Bacteristat Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Bruchiphobe * Cancer-Preventive 5-25 ug/ml Gawron, A. and Glowniak, K. 1987. Cytostatic Activity of Coumarins in vitro. Planta Medica 1987: 526. Carcinogenic 200 mg/kg orl mus Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Cardiodepressant * Cardiotonic * Chemopreventive * DME-Inhibitor IC50=57.5 uM Advance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 134. Emetic * Estrogenic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp. Fungicide Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Hemorrhagic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Hepatotoxic 2,500 ppm diet * Hepatotoxic 100 mg/kg dog * Hepatotoxic 0.8-1.71 mM/kg orl rat * Hypnotic Schultes, R.E. De Plantis Toxicariis e Mundo Novo Tropicale Commentationes XXXVI. Justicia (Acanthaceae) as a Source of an Hallucinogenic Snuff. Economic Botany 44(1): 61-70, 1990. Hypoglycemic 250-1,000 mg/kg orl Economic & Medicinal Plant Research, 6: 165 Immunostimulant * Juvabional Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Larvistat Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Lymphocytogenic 100 mg/day Gawron, A., Gorski, G., Glowniak, K. 1989. Increased proliferation of phytohaemagglutinin (PHA)-stimulated human leucocytes after 8-methoxypsoralen treatment. J. Pharm. Pharmacol. 42: 194-195, 1990. Lymphokinetic Narcotic * Ovicide * Pesticide * Phagocytotic Planta Medica, 56(6): 671, 1990. Piscicide Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Respirodepressant * Rodenticide Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Sedative Schultes, R.E. De Plantis Toxicariis e Mundo Novo Tropicale Commentationes XXXVI. Justicia (Acanthaceae) as a Source of an Hallucinogenic Snuff. Economic Botany 44(1): 61-70, 1990.
0	EMULSIN	Plant	430000.0	450000.0	--	*
15	MALIC-ACID	Plant	--	--	--	*
Antiatherosclerotic * Antibacterial * Antifibromyalgic 300 mg 3x/day * Antioxidant Synergist Merck 11th Edition Antiseborrheic * Antiseptic Martindale's 29th Antitubercular * Antitumor Economic & Medicinal Plant Research, 6: 235. Bacteristat * Bruchiphobe Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Hemopoietic * Laxative? Lawrence Review of Natural Products, Sep-91. Mycobactericide * Pesticide * Sialogogue Martindale's 29th
2	MONOTROPEIN	Plant	--	--	--	*
Cathartic ED50=>500 mg/kg Wagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176) Laxative Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
0	NAPHTHALENE-DERIVATIVES	Plant	--	--	--	*
11	NICOTINIC-ACID	Plant	--	--	--	*
Antichilblain 50 mg/3x/day Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. AntiCrohn's Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antidote (pesticides) Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antischizophrenic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antithyrotoxic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Choleretic * Hypocholesterolemic 1-6 g/man/day Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Hypoglycemic * Insulinase-Inhibitor Economic & Medicinal Plant Research, 6: 157. Insulinotonic Economic & Medicinal Plant Research, 6: 157. Lipolytic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
0	NICOTINIC-ACID-AMIDE	Plant	--	--	--	*
0	RUBRICHLORIC-ACID	Plant	--	--	--	*
41	TANNIC-ACID	Plant	--	--	--	*
Aldose-Reductase-Inhibitor IC50=1.8 ug/ml Sawada, H., Hamatake, M., Hara, A., Nakagawa, M., Nakayama, T. 1989. Inhibition of Human Placenta Aldose Reductase by Tannic Acid. Chem Pharm Bull, 37(6): 1662-1664. Allergenic * Antianacarditic (Rhus) * Antibacterial * Anticariogenic * Anticolitic * Antidecubitic * Antidermatotic * Antidiarrheic * Antidote For Heavy Metals Merck 11th Edition Antidysenteric Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. Antiencephalitic Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart. Antienteritic Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart. Antifeedant 2-4% diet * Antigargantitic * Antigingivitic * Antihemorrhoidal Martindale's 29th Antiherpetic * AntiHIV IC90=200 ug/ml Tan, G.T., Pezzuto, J.M., Kinghorn,* A.D., Hughes, S.H. Evaluation Of Natural Products As Inhibitors Of Human Immunodeficiency Virus Type 1 (HIV-1) Reverse Transcriptase. Journal of Natural Products, 54(1): 143-154, 1991. Antimutagenic Economic & Medicinal Plant Research, 6: 235. Antinitrosaminic * Antiobesity (Antinutrient) Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. Antiophidic * Antioxidant IC56=30 ppm * Antipharyngitic * Antipolio Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart. Antirhinitic * Antiseptic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Antistomatitic * Antitonsilitic * Antiulcer Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. Antiviral Antiviral Research, 14: 323. Astringent Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Cytotoxic 15 ug * Detoxicant Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. Emetic Martindale's 29th FLavor FEMA 1-1,000 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Hemostat Merck 11th Edition Hepatotoxic Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. Immunostimulant McKenna, D. J., Hughes, K., and Jones, K. 2000. Green Tea Monograph. Alternative Therapies, 6(3): 61-82. Pesticide *
35	TANNIN	Plant	--	--	--	*
Anthelmintic * Antibacterial * Anticancer * Anticariogenic * Antidiarrheic * Antidysenteric * Antihepatotoxic * AntiHIV * Antihypertensive * Antilipolytic * Antimutagenic * Antinephritic Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990. Antiophidic Economic & Medicinal Plant Research, 5: 363. Antioxidant IC50=1.44 ug/ml * Antioxidant 1/3 quercetin * Antiradicular 500 mg/kg/day orl mus Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990. Antiradicular 1/3 quercetin * Antirenitic Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990. Antitumor * Antitumor-Promoter * Antiulcer * Antiviral * Cancer-Preventive HerbalGram No. 22 - Spring 1990, page 14. Carcinogenic * Chelator * Cyclooxygenase-Inhibitor * Glucosyl-Transferase-Inhibitor * Hepatoprotective * Immunosuppressant * Lipoxygenase-Inhibitor * MAO-Inhibitor * Ornithine-Decarboxylase-Inhibitor * Pesticide * Psychotropic Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990. Xanthine-Oxidase-Inhibitor *

^*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.

Plant Galium odoratum (Rubiaceae)

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