Curcuma zedoaria | Plant | Dr. Duke's Phytochemical and Ethnobotanical Databases

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Common name(s)

Shoti, Zedoary

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Medicinal

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Activities: 212

Chemicals w/Activities: 19

All Chemicals: 50

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# Activity	Chemical Name	Part Filter by plant part	Low PPM	High PPM	StdDev	^*Reference
0	1,4-CINEOLE	Rhizome	--	--	--	Chemical Constituents of Oriental Herbs (3 diff. books)
67	1,8-CINEOLE	Rhizome	902.0	1920.0	-0.59	*
(-)-Chronotropic 87 nl/ml Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin. (-)-Inotropic 87 nl/ml Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin. Acaricide LC100=6 uM * Allelopathic * Allergenic * Anesthetic * Anthelmintic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antiacetylcholinesterase IC50=41 ug/ml * Antiallergic J. Food Hyg. Soc. Jap. 33(6): 569. Antibacterial 50 ppm * Antibronchitic * Anticariogenic * Anticatarrh Martindale's 29th Anticholinesterase IC50=50-70 * Antifatigue * Antihalitosic American Health, 12(4): 17, 1993. Antiinflammatory * Antilaryngitic * Antinociceptive * Antipharyngitic * Antiplaque * Antirheumatic * Antirhinitic * Antiseptic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antisinusitic * Antispasmodic * Antistaphylococcic 50 ppm * Antitussive * Antiulcer * Candidicide * Carcinogenic Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253. Choleretic * CNS-Stimulant * Convulsant * Counterirritant Martindale's 29th Cytochrome-P450-Inducer * Decongestant * Degranulant 0.3 ul/ml * Dentifrice Martindale's 29th Edemagenic inj * Expectorant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. FLavor FEMA 1-200 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Fungicide * Gastroprotective * Gram(+)icide * Gram(-)icide * Hepatotonic * Herbicide IC50=78 uM Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp. Hypotensive * Inflammatory inj * Insectifuge * Irritant Rinzler, C. A. 1990. The Complete Book of Herbs, Spices and Condiments. Facts on File, New York. 199 pp. Myorelaxant Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp. Nematicide Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp. Neurotoxic * P450-Inducer * Pediculicide 2.3 x pyrethrin * Perfume Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Pesticide * Rubefacient Martindale's 29th Secretogogue * Sedative * Spasmogenic * Surfactant * Testosterone-Hydroxylase-Inducer * Transdermal * Trichomonicide LD100=1,000 ug/ml *
28	ALPHA-PINENE	Rhizome	--	--	--	Chemical Constituents of Oriental Herbs (3 diff. books)
Allelochemic * Allergenic * Antiacne * Antibacterial * Antifeedant * Antiflu Economic & Medicinal Plant Research, 5: 195. Antiinflammatory 500 mg/kg * Antipneumonic * Antiseptic * Antispasmodic * Antistaphylococcic * Antiviral Economic & Medicinal Plant Research, 5: 195. Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Coleoptophile * Expectorant Michael Castleman 1991. The Healing Herbs. Rodale Press, Emmaus, PA 436 pp. FLavor FEMA 15-150 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Herbicide IC50=30 uM Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp. Insecticide 0.82 uM/fly * Insectifuge 50 ppm * Insectiphile J. Stored. Prod. Res., 22:141, 1986. Irritant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. P450-2B1-Inhibitor IC50=0.087 uM * Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Pesticide * Sedative Lawrence Review of Natural Products, Jun-90. Spasmogenic * Tranquilizer Lawrence Review of Natural Products, Jun-90. Transdermal *
0	AMYLOSE	Tuber	--	--	--	ANON. 1948-1976. The Wealth of India raw materials. Publications and Information Directorate, CSIR, New Delhi. 11 volumes.
5	BIS-DESMETHOXYCURCUMIN	Rhizome	0.0	1000.0	-1.00	*
Antialzheimeran 0.5-10 ug/ml * Antiamyloid-Beta 0.5-10 ug/ml * Antiangiogenic * Anticholeretic HerbalGram No. 17. Antiinflammatory Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
0	BISMETHOXYCURCUMIN	Rhizome	--	--	--	*
0	CURCULONE	Rhizome	--	--	--	*
0	CURCUMADIOL	Rhizome	--	--	--	Chemical Constituents of Oriental Herbs (3 diff. books)
0	CURCUMANOLIDE-A	Rhizome	--	--	--	Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
0	CURCUMANOLIDE-B	Rhizome	--	--	--	Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
3	CURCUMENOL	Rhizome	--	--	--	*
Anticancer Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. Antitumor Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. Emetic Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
0	CURCUMENONE	Rhizome	--	--	--	Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
135	CURCUMIN	Rhizome	0.0	1000.0	-0.89	*
12-Lipoxygenase-Inhibitor * 5-Alpha-Reductase-Inhibitor * 5-HETE-Inhibitor IC50=3-10 uM * 5-Lipoxygenase-Inhibitor * 8-HETE-Inhibitor IC40=3 uM * Antiadenomacarcinogenic 50-200 mg/kg ipr rat * Antiaflatoxin IC50=81 uM * Antiaggregant * Antialzheimeran 0.5-10 ug/ml * Antiamyloid-Beta 0.5-10 ug/ml * Antiangiogenic * Antiarachidonate * Antiarthritic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antiasthmatic * Antiatherosclerotic 0.4-20 mg/kg/day * Antibacterial Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp. Antibronchitic * Anticancer * Anticancer (Breast) * Anticancer (Colon) * Anticancer (Duodenum) * Anticancer (Mammary) 50-200 mg/kg ipr rat * Anticancer (Skin) * Anticancer (Stomach) * Anticarcinogenic * Anticataract 75 mg/kg orl rat * Anticholecystosic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Anticolitic * Anticollagenic * AntiCrohn's * AntiEBV IC50=5.4 uM * Antieczemic Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp. Antiedemic ED50=100.2 mg/kg orl mus (cf 78 for cortisone) * Antiedemic ED50=48 mg/kg orl rat (cf 45 for cortisone) * Antiedemic ED50=48 mg/kg orl rat (cf 48 for phenylbutazone) * Antieicosanoid * Antihepatotic * AntiHIV IC50=40 uM * Antiinflammatory 1,200 mg/man/day * Antiinflammatory 1 uM * Antiintegrase 40-150 uM * Antiischemic * Antileishmanic IC50=7.8 ug/ml * Antileukemic * Antileukotriene 170 mg/kg orl rat * Antilipoperoxidant * Antilithic 0.5% diet * Antilymphomic 4 ug/ml Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Antilymphomic 0.4 mg/ml Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp. Antimelanomic 200 nM/kg orl mus * Antimetastatic 200 nM/kg orl mus * Antimutagenic * Antinitrosaminic * Antioxidant 1/3 BHA * Antioxidant IC50=500 uM * Antipapillomic * Antiperoxidant * Antiproliferant IC50=13 uM * Antiprostaglandin 8.8 uM * Antipsoriatic * Antispasmodic =ICMR(Indian Council of Medical Research).1976.Medicinal Plants of India.Vol.1.Indian Council of Med. Res.Cambridge Printing Works, New Delhi.487 pp;ICMR.1987.Medicinal Plants of India.Vol.2.Indian Council of Med. Res.Cambr. Printing Works,New Delhi.600pp Antithrombotic * Antithromboxane * Antitumor * Antitumor (Colon) * Antitumor (Liver) 10 uM * Antitumor-Promoter IC91=10 uM * Antiulcer orl rat * Antiviral IC50=5.4 uM * Apoptotic 150-2,000 ppm (diet) orl rat * Apoptotic 30-90 uM * Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Cardiodepressant =ICMR(Indian Council of Medical Research).1976.Medicinal Plants of India.Vol.1.Indian Council of Med. Res.Cambridge Printing Works, New Delhi.487 pp;ICMR.1987.Medicinal Plants of India.Vol.2.Indian Council of Med. Res.Cambr. Printing Works,New Delhi.600pp Chelator Iron * Chelator IC50=500 uM * Chemopreventive * Cholagogue * Choleretic HerbalGram No. 24, page 37. COX-2-Inhibitor 10-20 uM * Cyclooxygenase-Inhibitor * Cytochrome-P450-Inhibitor Pizzorno, J. 1998. Total Wellness. Prima Health, a division of Prima. Cytotoxic 0.4-4 mg/ml Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp. Cytotoxic IC50=1 ug/ml * Cytotoxic IC50=25 uM * Deodorant Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp. Detoxicant * DNA-Protective * Dye Merck 11th Edition Expectorant 100 uM * Fibrinolytic * Fungicide * Glutathionigenic 80 mg/kg igs rat * Hepatoprotective 30 ppm * Hepatoprotective 30 mg/kg/day * Hypocholesterolemic 0.15% diet 7 wks * Hypolipidemic 0.15% diet 7 wks * Hypotensive * IkappaB-alpha-Phosphorylation-Inhibitor * IKB-kinase-Inhibitor * IKK-Inhibitor * Immunostimulant 40 mg/kg/5 wk orl rat * Lipase-Inducer * Litholytic 0.5% diet * Maltase-Promoter * MDR-Inhibitor 1-55 uM * Metal-Chelator McEvily, A.J., Iyengar, R., and Gross, A.T. Inhibition of Polyphenol Oxidase by Phenolic Compounds. Phenolic Compounds in Food and Their Effects on Health, Ch.25. MMP-9-Inhibitor 10 uM * Mucogenic 100 uM * Nematicide * Neuroprotective 80 mg/kg igs rat * NF-kB-Inhibitor * NO-Inhibitor * NO-Scavenger * Ornithine-Decarboxylase-Inhibitor ED=~150 mg/kg * P450-Inhibitor IC50=2-14 ug/ml * Pesticide * PGE2-Inhibitor IC42=3 uM * Phototoxic Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp. Plasmodicide * Prostaglandin-Synthesis-Inhibitor 0.2% diet rat Rao, C. V., Rivenson, A., Simi, B., Reddy, B. S. 1995. Chemoprevention of Colon Carcinogenesis by Dietary Curcumin, a Naturally Occurring Plant Phenolic Compound. Cancer Research, 55(2): 259-266. Protease-Inhibitor IC50=11-250 uM * Protein-Kinase-C-Inhibitor IC69=15 uM * Protein-Kinase-C-Inhibitor IC50=15 uM * Protein-Kinase-Inhibitor * PTK-Inhibitor 5-100 uM * Pulmonoprotective 200 mg/kg/7 d * Quinone-Reductase-Inducer 3.4 uM Singletary, K., et al. 1998. Effect of the Beta-Diketones Diferoloylmethane (Curcumin) and Dibenzoylmethane on Rat Mammary DNA Adducts and Tumors Induced by 7,12-dimethylbenz(A)anthracene. Carcinogenesis, 19(6): 1039-1043. Radioprotective * Sortase-A-Inhibitor IC50=13-14 ug/ml * Sucrase-Promoter * TNF-Inhibitor * Topoisomerase-I-Inhibitor * Topoisomerase-II-Inhibitor * Ulcerogenic orl rat * VEGF-Inhibitor *
3	CURCUMOL	Rhizome	--	--	--	Chemical Constituents of Oriental Herbs (3 diff. books)
Anticancer (Cervix) * Antisarcomic * Antitumor (Cervix) *
6	CURDIONE	Rhizome	--	--	--	Chemical Constituents of Oriental Herbs (3 diff. books)
Anticancer (Cervix) Medicinal and Poisonous Plants of the Tropics. Leeuwenberg, A.J.M., ed. Pudoc, Wageningen. 1987. Antileukopenic Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. Antisarcomic * Antitumor * Antitumor (Cervix) Medicinal and Poisonous Plants of the Tropics. Leeuwenberg, A.J.M., ed. Pudoc, Wageningen. 1987. AntiX-Radiation Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
0	CURZERENONE	Rhizome	--	--	--	Chemical Constituents of Oriental Herbs (3 diff. books)
0	D-ALPHA-PINENE	Rhizome	141.0	300.0	--	ANON. 1948-1976. The Wealth of India raw materials. Publications and Information Directorate, CSIR, New Delhi. 11 volumes.
4	D-BORNEOL	Rhizome	141.0	300.0	-1.00	*
Convulsant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253. Emetic Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253. Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253. Perfume Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
0	D-CAMPHENE	Rhizome	329.0	700.0	1.00	*
0	D-CAMPHOR	Rhizome	395.0	840.0	-1.05	*

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^*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.

Plant Curcuma zedoaria (Zingiberaceae)

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