An official website of the United States government.
Plant Cornus florida (Cornaceae)
Download a full report in PDF format
Common name(s)
American Dogwood
How used
Medicinal
Data Views
| # Activity | Chemical Name | Part | Low PPM | High PPM | StdDev | *Reference |
|---|---|---|---|---|---|---|
| 0 | ASH | Seed | -- | 36000.0 | -0.36 | * |
| 22 | BETULINIC-ACID | Bark | -- | 20000.0 | 2.00 | Jim Duke's personal files. |
|
Anthelmintic
*
Antibacterial
*
Anticancer
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Anticarcinomic
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiedemic
*
AntiHIV EC50=2.0 ug/ml
Kashiwada, Y., et. al. 1998. Anti-AIDS Agents. 30. Anti-HIV Activity of Oleanolic Acid, Pomolic Acid, and Structurally Related Triterpenoids. J. Nat. Prod., 61 (9): 1090-1095.
AntiHIV IC50=6.5 ug/ml
*
AntiHIV 14.8 uM
*
Antiinflammatory
Recio, M., et al. 1994. Investigations on the Steroidal Anti-Inflammatory Activity of Triterpenoids from Diospyros leucomelas*. Planta Medica, 61: 9.
Antileukemic
*
Antimalarial IC50=19-26 ug/ml
*
Antimelanomic
New York Times, 3/28/95.
Antinociceptive
*
Antiplasmodial IC50=19-26 ug/ml
*
Antitumor
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiviral 14.8 uM
*
Apoptotic
*
Cytotoxic 50-100 ppm
Biosyn. Prod. Cancer Chemotherapy (Petit et al)
Cytotoxic 16.4 uM
*
Phospholipase-A2-Inhibitor
*
Prostaglandin-Synthesis-Inhibitor 200 ug/ml
Dunstan, C. A., Liu, B., Welch, C. J., Perera, P., Bohlin, L. 1998. Alphitol, a Phenolic Substance from Alphitonia zizyphoides which Inhibits Prostaglandin Biosynthesis in vitro. Phytochemistry, 48(3): 495-497.
Prostaglandin-Synthesis-Inhibitor IC50=101 uM
Huang, C., Tunon, H., Bohlin, L. 1995. Anti-Inflammatory Compounds Isolated from Menyanthes trifoliata L. Yao Hsueh Hsueh Pao, 30(8): 621-626.
|
||||||
| 22 | BETULINIC-ACID | Bark | -- | 20000.0 | 2.00 | Pavannasasivam, G., & M.U.S. Sultanbawa. 1974. Betulinic acid in the Dilleniaceae and a review of its natural distribution. Phytochem. 13:2002-2006. |
|
Anthelmintic
*
Antibacterial
*
Anticancer
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Anticarcinomic
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiedemic
*
AntiHIV EC50=2.0 ug/ml
Kashiwada, Y., et. al. 1998. Anti-AIDS Agents. 30. Anti-HIV Activity of Oleanolic Acid, Pomolic Acid, and Structurally Related Triterpenoids. J. Nat. Prod., 61 (9): 1090-1095.
AntiHIV IC50=6.5 ug/ml
*
AntiHIV 14.8 uM
*
Antiinflammatory
Recio, M., et al. 1994. Investigations on the Steroidal Anti-Inflammatory Activity of Triterpenoids from Diospyros leucomelas*. Planta Medica, 61: 9.
Antileukemic
*
Antimalarial IC50=19-26 ug/ml
*
Antimelanomic
New York Times, 3/28/95.
Antinociceptive
*
Antiplasmodial IC50=19-26 ug/ml
*
Antitumor
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiviral 14.8 uM
*
Apoptotic
*
Cytotoxic 50-100 ppm
Biosyn. Prod. Cancer Chemotherapy (Petit et al)
Cytotoxic 16.4 uM
*
Phospholipase-A2-Inhibitor
*
Prostaglandin-Synthesis-Inhibitor 200 ug/ml
Dunstan, C. A., Liu, B., Welch, C. J., Perera, P., Bohlin, L. 1998. Alphitol, a Phenolic Substance from Alphitonia zizyphoides which Inhibits Prostaglandin Biosynthesis in vitro. Phytochemistry, 48(3): 495-497.
Prostaglandin-Synthesis-Inhibitor IC50=101 uM
Huang, C., Tunon, H., Bohlin, L. 1995. Anti-Inflammatory Compounds Isolated from Menyanthes trifoliata L. Yao Hsueh Hsueh Pao, 30(8): 621-626.
|
||||||
| 28 | CALCIUM | Plant | -- | -- | -- | * |
|
Antiallergic 500 mg/day
*
Antianxiety
Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Antiarrhythmic 500-1,500 mg
*
Antiarthritic 1,000 mg/day
*
Antiatherosclerotic 500 mg/day
Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
Anticlimacteric 1,000-1,500 mg/day
*
Antidepressant
Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Antidote (Aluminum)
Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Antidote (Lead)
Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Antihyperkinetic
Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Antihypertensive
*
Antiinsomniac
Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Antimenopausal 1,000-1,500 mg/day
*
Antiobesity
*
Antiosteoporotic 500-2,000 mg/day
*
Antiperiodontitic 750 mg/day
Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
AntiPMS 1 g/day
*
Antirheumatic 1,000 mg/day
*
Antistress 500-1,500 mg/day
*
Antitic
Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Anxiolytic 500-1,500 mg/day
*
Calcium-Channel-Blocker
*
Diuretic
*
Hypocholesterolemic 500 mg/day
Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
Hypotensive 1 g/day
Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
Laxative 1,000-1,200 mg
*
Tranquilizer 500-1,500 mg/day
*
Vasodilator
*
|
||||||
| 0 | CARBOHYDRATES | Seed | -- | 733000.0 | 0.83 | * |
| 0 | FAT | Seed | 24000.0 | 494000.0 | 1.20 | * |
| 15 | FIBER | Seed | -- | 160000.0 | 0.20 | * |
|
Angiotensin-Receptor-Blocker
*
Antidiabetic
*
Antihypertensive
*
Antiobesity
*
Antitumor
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiulcer
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Beta-Blocker
*
Cancer-Preventive
Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Cardioprotective
*
Diuretic
*
Hypocholesterolemic
*
Hypotensive 10 g/man/day/orl
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Hypouricemic
*
Laxative
*
Vasodilator
*
|
||||||
| 62 | GALLIC-ACID | Bark | -- | -- | -- | * |
|
ACE-Inhibitor IC50=7.7 mM/l
*
Analgesic
*
Antiadenovirus
Economic & Medicinal Plant Research, 5: 194.
Antiallergenic
Dorsch, W., Wagner, H. New Antiasthmatic Drugs from Traditional Medicine? Int Arch Allergy Appl Immunol 94: 262-265, 1991.
Antianaphylactic
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiangiogenic
*
Antiasthmatic
Watt, J.M., and Breyer-Brandwijk, M.G. The Medicinal and Poisonous Plants of Southern and Eastern Africa. 1962.
Antibacterial MIC=1,000 ug/ml
*
Antibronchitic
Dorsch, W., Wagner, H. New Antiasthmatic Drugs from Traditional Medicine? Int Arch Allergy Appl Immunol 94: 262-265, 1991.
Anticancer
*
Anticarcinomic ED50=3
*
Antiescherichic
*
Antifibrinolytic
Economic & Medicinal Plant Research, 1: 53.
Antiflu
Economic & Medicinal Plant Research, 5: 194.
Antihepatotoxic
Okuda, T., Yoshida, T., and Hatano, T. Antioxidant Effects of Tannins and Related Polyphenols. Phenolic Compounds in Food and Their Effects on Health, Ch.7 p.93.
Antiherpetic EC50=>10 ug/ml
*
AntiHIV
*
Antiinflammatory
Kroes, B.H., et al. 1991. Anti-Inflammatory Activity of Gallic Acid. Planta Medica, 58(6): 499.
Antileishmanic EC50=4.4 ug/ml
*
AntiMRSA
*
Antimutagenic
Economic & Medicinal Plant Research, 6: 235.
Antinitrosaminic
*
Antioxidant 2/3 BHA
*
Antioxidant 7 x quercetin
*
Antioxidant IC44=33 ppm
*
Antiperiodontitic 10 ug/ml
*
Antiperoxidant IC50=69 uM
*
Antipolio
Economic & Medicinal Plant Research, 5: 194.
Antiproteolytic 10 ug/ml
*
Antiradicular IC50=4.9 uM
*
Antiradicular 7 x quercetin
*
Antiseptic
Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Antistaphylococcic MIC=1,000 ug/ml
*
Antitumor
*
Antitumor-Promoter
*
Antiviral
*
Apoptotic
*
Astringent
Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Bacteristat
Lamikanra, A., Ogundaini, A.O., and Ogungbamila*, F.O. Antibacterial Constituents of Alchornea cordifolia Leaves. Phytotherapy Research 4(5): 198.
Bronchodilator
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Cancer-Preventive
Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidicide
*
Carcinogenic
*
Choleretic
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Cyclooxygenase-Inhibitor
*
Cytotoxic 500 uM
*
Floral-Inhibitor
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Gram(+)icide MIC=1,000 ug/ml
*
Gram(-)icide MIC=1,000 ug/ml
*
Hemostat
*
Hepatoprotective
Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
Immunomodulator
*
Immunostimulant
McKenna, D. J., Hughes, K., and Jones, K. 2000. Green Tea Monograph. Alternative Therapies, 6(3): 61-82.
Immunosuppressant
*
Insulin-Sparing
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Myorelaxant
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Nephrotoxic
Martindale's 29th
NO-Inhibitor IC-26=250 uM
*
Pesticide
*
Styptic
*
Topoisomerase-I-Inhibitor
Hamada, S. I., Kataoka, T., Woo, J. T., Yamada, A., Yoshida, T., Nishimura, T., Otake, N., Nagai, K. 1997. Immunosuppressive Effects by Gallic Acid and Chebulagic Acid on CTL-Mediated Cytotoxicity. Biol Pharm Bull, 20: 1017-1019.
Xanthine-Oxidase-Inhibitor IC50=24 uM
Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
|
||||||
| 8 | INOSITOL | Flower | -- | -- | -- | * |
|
Antialopecic
*
Anticirrhotic
*
Antidiabetic?
Martindale's 29th
Antineuropathic? 2 g/day
Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
Cholesterolytic 2,000 mg/man/day
*
Lipotropic
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Sweetener
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Ubiquiot
Duke, J. A. Writeups or information summaries on approximately 2,000 economic plants, USDA, ARS, Beltsville, MD 20705.
|
||||||
| 75 | KAEMPFEROL | Flower | -- | -- | -- | * |
|
11B-HSD-Inhibitor
*
5-Lipoxygenase-Inhibitor IC50 (uM)=20
*
Aldose-Reductase-Inhibitor 100 uM
Oliveira, T. T., Nagem, T. J., Miranda, L. C. G., Paula, V. F., Teixeira, M. A. 1997. Inhibitory Action on Aldose Reductase by Soybean Flavonoids. J Braz Chem Soc, 8(3): 211-213.
Antiaflatoxin IC50=8.73 uM
*
Antiaflatoxin IC50=3.28 ppm
*
Antiaggregant 30 uM
*
Antiallergic
*
Antibacterial 20 ug/ml
*
Anticancer
*
Antifertility 250 mg/kg/day/60 days/orl rat
Kumar, P., Dixit*, V.P., and Khanna, P. Antifertility Studies of Kaempferol: Isolation and Identification from Tissue Culture of some Medicinally Important Plant Species. Plantes medicinales et phytotherapie, 23: 193-201, 1989.
Antigingivitic 20 ug/ml
*
Antiherpetic 23-92 ug/ml
Amoros, M., Simoes, C.M.O., Girre, L., et al. Synergistic Effect Of Flavones And Flavonols Against Herpes Simplex Virus Type 1 In Cell Culture. Comparison With The Antiviral Activity Of Propolis. J. of Natural Products 55(12):1732-1740, 1992.
Antihistaminic
Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Antiimplantation
*
Antiinflammatory 20 mg/kg
*
Antiinflammatory 200 mg/kg ipr rat
*
Antileukemic IC50=3.1 ug/ml
Life Sciences 55: 1061.
Antilymphocytic
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antimutagenic ID50=10-40 nM
Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
Antioxidant IC50=40 uM
*
Antioxidant IC50=1.2 ug/ml
*
Antioxidant 3/4 quercetin
*
Antiperiodontic 20 ug/ml
*
Antiplaque 20 ug/ml
*
Antiradicular 7 x quercetin
*
Antiseptic 20 ug/ml
*
Antiserotonin 200 mg/kg ipr rat
*
Antispasmodic
Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Antistaphylococcic
*
Antitumor
*
Antitumor-Promoter
Yasukawa, K., Takido, M., Takeuchi, M., Sato, Y., Nitta, K., and Nakagawa, S. 1989. Inhibitory Effects of Flavonol Glycosides on 12-O-Tetradecanoylphorbol-13-acetate-Induced Tumor Promotion. Chem. Pharm. Bull. 38(3): 774-776, 1990.
Antiulcer 50-200 mg/kg ipr rat
*
Antiviral 23-92 ug/ml
*
Apoptotic 60 uM
*
Aromatase-Inhibitor IC12=1 uM/l
Journal of Medicinal Food 2: 235.1999.
cAMP-Phosphodiesterase-Inhibitor
*
Cancer-Preventive
Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Carcinogenic
Hutchings, A, Scott, AH, Lewis, G, and Cunningham, A. 1996. Zulu
Medicinal Plants. An inventory. University of Natal Press, Pietermaritzburg. 450 pp.
Choleretic
Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Copper-Chelator
*
COX-2-Inhibitor
*
Cyclooxygenase-Inhibitor IC50 (uM) =20
*
Cytotoxic
*
Diaphoretic?
Lawrence Review of Natural Products, Dec-90.
Diuretic
*
Estrogenic EC50=0.56 uM
*
Estrogenic EC50=0.1-25 uM/l
Journal of Medicinal Food 2: 227.1999.
Fungicide 20 ug/ml
Father Nature's Farmacy: The aggregate of all these three-letter citations.
Hepatoprotective IC50=5.46 uM
*
Hepatoprotective IC50=1.30 ppm
*
HIV-RT-Inhibitor IC50=50-150 ug/ml
Garcia, J., Morin,* C., Nyasse, B., Sondengam, B-L., Tchouankeu, J-C., and Tsamo, E. Complete Structural Assignments Of An Ergosterol Derivative From Entandrophragma utile. Journal of Natural Products, 54(1): 136-142, 1991.
Hypotensive
*
ICAM-1-Inhibitor
*
iNOS-Inhibitor IC50=<15 uM
*
iNOS-Inhibitor IC50=13.9 uM
*
Inotropic
*
Iodothyronine-Deiodinase-Inhibitor
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
JNK-Inhibitor
*
Lipoxygenase-Inhibitor
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
MAO-Inhibitor
*
Mutagenic
*
Natriuretic
*
Neuroprotective
*
NO-Inhibitor IC50=13.9 uM
*
PAF-Inhibitor
*
Pesticide
*
Protisticide
Meckes, M., Calzada, F., Tapia-Contreras, A., Cedillo-Rivera, R. 1999. Antiprotozoal Properties of Helianthemum glomeratum. Phytotherapy Research, 13(2): 102-105.
Quinone-Reductase-Inducer 3 uM
*
Teratologic
*
TNF-alpha-Inhibitor IC50=3.99 uM
*
Topoisomerase-I-Inhibitor
Santti, R., Makela, S., Strauss, L., Korman, J., Kostian, M. L. 1998. Phytoestrogens: Potential Endocrine Disruptors in Males. Toxicol Ind Health, 14: 223-237.
Topoisomerase-II-Inhibitor IC50=8.1 ug/ml
Constantinou, A., Mehta, R., Runyan, C., Rao, K., Vaughan, A., Moon, R. 1995. Flavonoids as DNA Topoisomerase Antagonists and Poisons: Structure-Activity Relationships. J Natural Products, 58: 217-225.
Tyrosinase-Inhibitor ID50=230 uM
*
Uterotrophic EC50=0.1-25 uM/l
Journal of Medicinal Food 2: 227.1999.
Vasodilator
*
|
||||||
| 1 | N-NONACOSANE | Flower | -- | -- | -- | * |
|
Antimutagenic
Economic & Medicinal Plant Research, 6: 235.
|
||||||
| 4 | PHOSPHORUS | Seed | -- | 1500.0 | -1.02 | * |
|
Antiosteoporotic
Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Anxiolytic
*
Immunostimulant
Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Osteogenic
Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
|
||||||
| 0 | PROTEIN | Seed | 23000.0 | 390000.0 | 1.39 | * |
| 176 | QUERCETIN | Flower | -- | -- | -- | * |
|
11B-HSD-Inhibitor
*
5-Lipoxygenase-Inhibitor IC50 (uM)=4
*
Aldehyde-Oxidase-Inhibitor IC70-96=10 uM
*
Aldose-Reductase-Inhibitor 100 uM
*
Aldose-Reductase-Inhibitor 4 ug/ml
Ichikawa, K., et al. 1991. Isolation and Structure Determination of Aldose Reductase Inhibitors from Traditional Thai Medicine, and Syntheses of Their Derivatives. Sankyo Kenkyusho Nempo, 43: 99-110.
Aldose-Reductase-Inhibitor IC50=0.84 ug/ml cow
Okada,Y,et al.1995.Search for Naturally Occurring Substances to Prevent the Complications of Diabetes.II.Inhibitory Effect of Coumarin and Flavonoid Derivatives on Bovine Lens Aldose Reductase and Rabbit Platelet Aggregation.Chem Pharm Bull43(8):1385-1387
Aldose-Reductase-Inhibitor IC50=0.344 uM
Mao, X. M., Zhang, J. Q. 1993. Inhibition of Aldose Reductase by Extracts of Chinese Herbal Medicine. Zhongguo Zhongyao Zazhi , 18(10): 623-624.
Allelochemic IC82=1 mM
Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Allergenic
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Analgesic
*
Antiaflatoxin IC50=25 uM
*
Antiaflatoxin IC50=7.5 ppm
*
Antiaggregant 30 uM
*
Antiaggregant IC50=55 uM
Economic & Medicinal Plant Research, 5: 333.
Antiaging
*
Antiallergic IC50=14 uM
Jim Duke's personal files.
Antialzheimeran
*
Antianaphylactic
Meli, R., Autore, G., Di Carlo, G., Capasso, F. Inhibitory Action of Quercetin on Intestinal Transit in Mice. Phytotherapy Research 4(5): 201, 1990.
Antiangiogenic
*
Antiarthritic
*
Antiasthmatic IC50=14 uM
*
Antiatherosclerotic
*
Antibacterial
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Anticarcinomic (Breast) IC50=1.5 uM
Medline (post 1990 searches filed in my computer)
Anticariogenic ID50=120 ug/ml
*
Anticataract
*
Anticolitic 400 mg/man/3x/day
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Anticomplementary
*
AntiCrohn's 400 mg/man/3x/day
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Anticystitic 1,000 mg/day/4 weeks
*
Antidepressant
*
Antidermatitic
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antidiabetic
*
Antielastase IC50=0.8 ug/ml
*
Antiencephalitic
Economic & Medicinal Plant Research, 5: 199.
Antiescherichic
*
Antiestrogenic
*
Antifeedant IC52=<1,000 ppm diet
Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Antifibrosarcomic
*
Antiflu
Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
Antigastric
Rastitel'nye Resursy, 21: 85.
Antigonadotropic
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
AntiGTF ID50=120 ug/ml
*
Antihepatotoxic
Joyeux, M., Rolland, A., Fleurentin, J., Mortier, F., and Dorfman, P. 1989. Tert-Butyl Hydroperoxide-Induced Injury in Isolated Rat Hepatocytes: A Model for Studying Anti-Hepatotoxic Crude Drugs. Planta Medica 56(2): 171-173, 1990.
Antiherpetic 48-150 ug/ml
*
Antihistaminic IC50=<10 uM
*
AntiHIV
*
Antihydrophobic
Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
Antihypertensive
Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Antiinflammatory 20-150 mg/kg
Fitoterapia No.5-1990.
Antileishmanic IC50=64
*
Antileukemic 5.5-60 uM
*
Antileukemic IC50=10 uM
Economic & Medicinal Plant Research, 5: 225.
Antileukemic IC50=>10 ug/ml
Life Sciences 55: 1061.
Antileukotriene
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antilipoperoxidant IC67=50
*
Antimalarial IC50=1-6.4 ug/ml
Medicinal and Poisonous Plants of the Tropics. Leeuwenberg, A.J.M., ed. Pudoc, Wageningen. 1987.
Antimelanomic
*
Antimetastatic
*
Antimutagenic ID50=0.62 ug/ml
*
Antimutagenic ID50=2-5 nM
Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
Antimyocarditic
Economic & Medicinal Plant Research, 5: 199.
Antinitrosaminic
*
Antinociceptive
*
Antioxidant IC96=300 ppm
Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
Antioxidant ED50=2.3 uM
Seidel, V., Verholle, M., Malard, Y., Tillequin, F., Fruchart, J-C., Duriez, P., Bailleul, F., Teissier, E. 2000. Phenylpropanoids from Ballota nigra L. Inhibit in vitro LDL Peroxidation. Phytotherapy Research, 14(2): 93-98.
Antioxidant 4.7 x Vit. E
*
Antioxidant IC47=10 uM
*
Antipancreatitic
Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Antiperiodontal
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiperistaltic
*
Antipermeability
*
Antiperoxidant
Planta Medica, 57: A110, 1991.
Antipharyngitic
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiplaque
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiplasmodial IC50=13-64
*
AntiPMS 500 mg/2x/day/wmn
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antipodriac
*
Antipolio
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiproliferant 10 nM
*
Antiprostanoid
*
Antiprostatitic
Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Antipsoriac
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiradicular IC50=4.6 uM
Planta Medica, 56(6): 695, 1990.
Antispasmodic
*
Antistreptococcic ID50=120 ug/ml
*
Antithiamin
Phenolic Compounds in Food and Their Effects on Health, 69.
Antithrombic
*
Antitrypanosomic IC50=13
*
Antitumor 10 uM
*
Antitumor (Bladder)
*
Antitumor (Breast)
*
Antitumor (Colon)
*
Antitumor (Lung)
*
Antitumor (Ovary)
*
Antitumor (Skin) 20 uM
*
Antitumor-Promoter
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiulcer
*
Antiviral 48-150 ug/ml
Amoros, M., Simoes, C.M.O., Girre, L., et al. Synergistic Effect Of Flavones And Flavonols Against Herpes Simplex Virus Type 1 In Cell Culture. Comparison With The Antiviral Activity Of Propolis. J. of Natural Products 55(12):1732-1740, 1992.
Antiviral IC50=10 uM
Economic & Medicinal Plant Research, 5: 225.
Apoptotic 20-60 uM
*
ATPase-Inhibitor
Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Bacteristat 10 mg/ml
*
Bradycardiac
Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Calmodulin-Antagonist
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
cAMP-Phosphodiesterase-Inhibitor
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Cancer-Preventive
Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidicide
*
Capillariprotective
Merck 11th Edition
Carcinogenic 40,000 ppm (diet) mus
Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Catabolic
*
COMT-Inhibitor
*
Copper-Chelator
*
COX-2-Inhibitor <40 uM
*
Cyclooxygenase-Inhibitor
*
Cytochrome-P450-1A2-Inhibitor
*
Cytotoxic ED50=70 ug/ml
Matsukawa, Y., et al. The Effect of Quercetin and Other Flavonoids on Cell Cycle Progresssion and Growth of Human Gastric Cancer Cells. Planta Medica, 56(6): 677, 1990.
Cytotoxic IC82=100 ug/ml
Planta Medica, 57: A113, 1991.
Deiodinase-Inhibitor
Jim Duke's personal files.
Diaphoretic?
Lawrence Review of Natural Products, Dec-90.
Differentiator 5.5 uM
*
Estrogenic 10% genistein
*
Fungicide
*
Glucosyl-Transferase-Inhibitor ID50=120 ug/ml
*
Hemostat
Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Hepatomagenic 5,000 ppm (diet) rat
Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
Hepatoprotective
*
HIV-RT-Inhibitor IC50=<1 ug/ml
Nakane, H., Fukushima, M., and Ono*, K. Differential Inhibition Of Reverse Transcriptase And Various DNA Polymerases By Digallic Acid And Its Derivatives. Journal of Natural Products, 53(5): 1234-1240, 1990.
Hypoglycemic 100 mg/kg orl rat
Ivorra, M.D., Paya, M., and Villar, A. 1989. A Review of Natural Products and Plants as Potential Antidiabetic Drugs. Journal of Ethnopharmacology, 27: 243-275, 1989.
iNOS-Inhibitor IC50=20 uM
*
Inotropic
*
Insulinogenic
Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Juvabional
Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Larvistat 8,000 ppm diet
Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Lipoxygenase-Inhibitor IC11=1.25 mM
Oszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690.
Lipoxygenase-Inhibitor IC50=0.1-5 uM
*
MAO-A-Inhibitor
*
Mast-Cell-Stabilizer
*
Metal-Chelator (Copper)
Seidel, V., Verholle, M., Malard, Y., Tillequin, F., Fruchart, J-C., Duriez, P., Bailleul, F., Teissier, E. 2000. Phenylpropanoids from Ballota nigra L. Inhibit in vitro LDL Peroxidation. Phytotherapy Research, 14(2): 93-98.
Metalloproteinase-Inhibitor IC50=>42 uM
*
MMP-9-Inhibitor 20 uM
*
Mutagenic
*
NADH-Oxidase-Inhibitor
*
NEP-Inhibitor IC50=>42 uM
*
Neuroprotective 5-25 uM
*
NF-kB-Inhibitor
*
NO-Inhibitor IC>50=125 uM
*
NO-Inhibitor IC50=20 uM
*
NO-Synthase-Inhibitor 5-50 uM
*
Ornithine-Decarboxylase-Inhibitor <10 uM
*
P450-Inducer 5 uM
Father Nature's Farmacy: The aggregate of all these three-letter citations.
P450-Inhibitor 50-100 uM
Father Nature's Farmacy: The aggregate of all these three-letter citations.
Pesticide
*
PGE2-Inhibitor
*
Phospholipase-Inhibitor
*
Plasmodicide
Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
Proliferant
*
Prostaglandin-Synthesis-Inhibitor 40 ug/ml
Ibewuike, J. C., Ogungbamila, F. O., Ogundaini, A. O., Okeke, I. N., Bohlin, L. 1997. Antiinflammatory and Antibacterial Activities of C-methylflavonol from Piliostigma thonningii. Phytotherapy Research, 11(4): 281-284.
Protein-Kinase-C-Inhibitor
Naim, M., Zehavi, U., Nagy, S., and Rouseff, R.L. Hydroxycinnamic Acids as Off-Flavor Precursors in Citrus Fruits and Their Products. Phenolic Compounds in Food and Their Effects on Health, Ch.14.
PTK-Inhibitor 0.4-24 uM
*
Quinone-Reductase-Inducer 6 uM
Uda, Y., Price, K. R., Williamson, G., Rhodes, M. J. C. 1997. Induction of the Anticarcinogenic Marker Enzyme, Quinone Reductase, in Murine Hepatoma Cells In Vitro by Flavonoids. Cancer Lett., 120 (2): 213-216.
Quinone-Reductase-Inducer 13 uM
*
Teratologic
*
TNF-alpha-Inhibitor IC50=3.11 uM
*
Topoisomerase-I-Inhibitor IC50=42 uM
*
Topoisomerase-I-Inhibitor IC50=12.8 ug/ml
*
Topoisomerase-II-Inhibitor IC50=23-40 uM
*
Topoisomerase-II-Inhibitor IC50=1-6.9 ug/ml
*
Tumorigenic 0.1% diet orl rat/yr
Jim Duke's personal files.
Tyrosinase-Inhibitor ID50=70 uM
*
Tyrosine-Kinase-Inhibitor
Economic & Medicinal Plant Research, 6: 170.
Vasodilator
*
VEGF-Inhibitor
*
Xanthine-Oxidase-Inhibitor IC50=10.6 ug/ml
*
Xanthine-Oxidase-Inhibitor 3.1 uM
*
Xanthine-Oxidase-Inhibitor IC50=>0.4 ug/ml
Chem. & Pharm. Bull. 38: 1772.
|
||||||
| 0 | RESIN | Bark | -- | -- | -- | * |
| 0 | SCYLLITOL | Flower | -- | -- | -- | * |
| 35 | TANNIN | Bark | -- | 30000.0 | -0.97 | * |
|
Anthelmintic
*
Antibacterial
*
Anticancer
*
Anticariogenic
*
Antidiarrheic
*
Antidysenteric
*
Antihepatotoxic
*
AntiHIV
*
Antihypertensive
*
Antilipolytic
*
Antimutagenic
*
Antinephritic
Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990.
Antiophidic
Economic & Medicinal Plant Research, 5: 363.
Antioxidant IC50=1.44 ug/ml
*
Antioxidant 1/3 quercetin
*
Antiradicular 500 mg/kg/day orl mus
Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990.
Antiradicular 1/3 quercetin
*
Antirenitic
Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990.
Antitumor
*
Antitumor-Promoter
*
Antiulcer
*
Antiviral
*
Cancer-Preventive
HerbalGram No. 22 - Spring 1990, page 14.
Carcinogenic
*
Chelator
*
Cyclooxygenase-Inhibitor
*
Glucosyl-Transferase-Inhibitor
*
Hepatoprotective
*
Immunosuppressant
*
Lipoxygenase-Inhibitor
*
MAO-Inhibitor
*
Ornithine-Decarboxylase-Inhibitor
*
Pesticide
*
Psychotropic
Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990.
Xanthine-Oxidase-Inhibitor
*
|
||||||
| 89 | URSOLIC-ACID | Plant | -- | -- | -- | * |
|
Analgesic
*
Antialzheimeran
Ringbom, T., Seguar, L., Noreen, Y., Perera, P., Bohlin, L. 1998. Ursolic Acid from Plantago major, a Selective Inhibitor of Cyclooxygenase-2 Catalyzed Prostaglandin Biosynthesis. J. Nat. Prod., 61(10): 1212-1215.
Antiarrhythmic
*
Antiarthritic
Planta Medica, 57: A56, 1991.
Antibacterial
*
Anticancer
Ringbom, T., Seguar, L., Noreen, Y., Perera, P., Bohlin, L. 1998. Ursolic Acid from Plantago major, a Selective Inhibitor of Cyclooxygenase-2 Catalyzed Prostaglandin Biosynthesis. J. Nat. Prod., 61(10): 1212-1215.
Anticancer (Colon)
Ringbom, T., Seguar, L., Noreen, Y., Perera, P., Bohlin, L. 1998. Ursolic Acid from Plantago major, a Selective Inhibitor of Cyclooxygenase-2 Catalyzed Prostaglandin Biosynthesis. J. Nat. Prod., 61(10): 1212-1215.
Anticarcinomic
Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Anticariogenic
Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Anticholestatic 28-100 mg/kg orl
Shukla, B., Visen, P.K.S., Patnaik, G.K., Tripathi, S.C., Srimal, R.C., Dayal, R., and Dobhal, P.C. Hepatoprotective Activity in the Rat of Ursolic Acid Isolated from Eucalyptus Hybrid. Phytotherapy Research 6: 74-79, 1992.
Anticomplement IC100 0.1 mM/l gpg
Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
Anticomplement IC80-90 0.05 mM/l gpg
Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
Antidiabetic
Chemical Constituents of Oriental Herbs (3 diff. books)
AntiEBV
Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Antiedemic
*
Antiescherichic
*
Antifibrosarcomic IC80=10 uM
*
Antihepatotoxic 5-20 mg/kg ipr
Shukla, B., Visen, P.K.S., Patnaik, G.K., Tripathi, S.C., Srimal, R.C., Dayal, R., and Dobhal, P.C. Hepatoprotective Activity in the Rat of Ursolic Acid Isolated from Eucalyptus Hybrid. Phytotherapy Research 6: 74-79, 1992.
Antihistaminic
Tsuruga, T., Chun, Y.-T., Ebizuka, Y., and Sankawa, U. 1991. Biologically Active Constituents of Melaleuca leucadendron: Inhibitors of Induced Histamine Release from Rat Mast Cells. Chem. Pharm. Bull. 39(12): 3276-3278, 1991.
AntiHIV 6.7 uM
*
AntiHIV EC50=2.0 ug/ml
Kashiwada, Y., et. al. 1998. Anti-AIDS Agents. 30. Anti-HIV Activity of Oleanolic Acid, Pomolic Acid, and Structurally Related Triterpenoids. J. Nat. Prod., 61 (9): 1090-1095.
AntiHIV IC50=6.5 ug/ml
Kashiwada, Y., et. al. 1998. Anti-AIDS Agents. 30. Anti-HIV Activity of Oleanolic Acid, Pomolic Acid, and Structurally Related Triterpenoids. J. Nat. Prod., 61 (9): 1090-1095.
AntiHIV IC85=18 ug/ml
*
Antihyperlipidemic
*
Antiinflammatory 1/3 indomethacin
*
Antiinflammatory IC24=500 mg/kg
*
Antileishmanic ED50=20 uM
*
Antileukemic IC50=2.5-17.8 ug/ml
*
Antilymphomic
Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Antimalarial IC50=28-37 ug/ml
*
Antimetastatic IC80=10 uM
*
Antimutagenic IC57-80=80 mg/kg
*
Antinephritic IC50=6-7.5 uM
*
Antiobesity?
Internat. J. Oriental Med. 16: 4.
Antioxidant IC50=10 uM
*
Antiperoxidant IC35=200 ug/ml
*
Antiplasmodial IC50=28-37 ug/ml
*
Antiproliferative IC50=15-20 uM
*
Antistaphylococcic
*
AntiTGF-beta IC50=6-7.5 uM
*
Antithromboxane IC50=50 uM
*
Antitrypanosomic
*
Antitumor
Cancer Research, 54: 701, 1994.
Antitumor (brain)
Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor (Breast) 0.5% diet
*
Antitumor (Breast) IC50=15-20 uM
*
Antitumor (Cervix)
Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor (Colon)
*
Antitumor (Lung)
*
Antitumor (Ovary)
Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor (Stomach) IC50=15-20 uM
*
Antitumor-Promoter
Planta Medica, 57: A56, 1991.
Antiulcer
Shukla, B., Visen, P.K.S., Patnaik, G.K., Tripathi, S.C., Srimal, R.C., Dayal, R., and Dobhal, P.C. Hepatoprotective Activity in the Rat of Ursolic Acid Isolated from Eucalyptus Hybrid. Phytotherapy Research 6: 74-79, 1992.
Antiviral IC85=18 ug/ml
*
Aromatase-Inhibitor
*
Beta-Blocker
*
Beta-Glucuronidase-Inhibitor ~100 mg/kg
*
Cancer-Preventive
Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidicide
*
Cardioprotective
*
Cardiotonic
*
Choleretic 5-20 mg/kg orl
Shukla, B., Visen, P.K.S., Patnaik, G.K., Tripathi, S.C., Srimal, R.C., Dayal, R., and Dobhal, P.C. Hepatoprotective Activity in the Rat of Ursolic Acid Isolated from Eucalyptus Hybrid. Phytotherapy Research 6: 74-79, 1992.
CNS-Depressant
*
COX-2-Inhibitor IC50=130 uM/
*
Cyclooxygenase-Inhibitor
Ringbom, T., Seguar, L., Noreen, Y., Perera, P., Bohlin, L. 1998. Ursolic Acid from Plantago major, a Selective Inhibitor of Cyclooxygenase-2 Catalyzed Prostaglandin Biosynthesis. J. Nat. Prod., 61(10): 1212-1215.
Cytotoxic ED50=3.75 ug/ml
*
Cytotoxic 50 ppm
*
Cytotoxic 7.2 uM
*
Diuretic
*
Elastase-Inhibitor IC50=~15 uM
*
Hepatoprotective 10 mg/kg
*
Hepatoprotective 1-100 ug/ml
*
Hypoglycemic
Ivorra, M.D., Paya, M., and Villar, A. 1989. A Review of Natural Products and Plants as Potential Antidiabetic Drugs. Journal of Ethnopharmacology, 27: 243-275, 1989.
Hypotensive
*
Immunomodulator
*
Leucocytogenic
*
Lipoxygenase-Inhibitor IC50=0.18 mM
*
MMP-9-Inhibitor IC80=10 uM
*
Ornithine-Decarboxylase-Inhibitor
*
Pesticide
*
Piscicide
*
Potassium-Sparing 3 mg/rat
Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Protease-Inhibitor IC85=18 ug/ml
*
Protisticide
Chemical Express, 7: 285, 1992.
Quinone-Reductase-Inducer 5 ug/ml
Lee, S. K., Song, Y., Mata-Greenwood, E., Kelloff, G. J., Steele, V. E., Pezzuto, J. M. 1999. Modulation of in vitro Biomarkers of the Carcinogenic Process by Chemopreventive Agents. Anticancer Res., 19: 35-44.
Sodium-Sparing 3 mg/rat
Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
TOPO-2-Inhibitor
*
Trypanocide
*
Vasopressor
*
|
||||||
| 7 | VERBENALIN | Bark | -- | -- | -- | * |
|
Abortifacient
*
Cathartic ED50=110 mg/kg
Wagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
CNS-Stimulant
*
Coagulant
*
Parasympathicomimetic
Wagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
Purgative
Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Uterotonic
Wagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
|
||||||
| # Activity | Chemical Name | Part | Low PPM | High PPM | StdDev | *Reference |
|---|
| # Chemical | Activity Name | *Reference |
|---|---|---|
 |
||
*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.