Cassia tora | Plant | Dr. Duke's Phytochemical and Ethnobotanical Databases

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Common name(s)

Sickle Senna

How used

Medicinal

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Activities: 246

Chemicals w/Activities: 28

All Chemicals: 46

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# Activity	Chemical Name	Part Filter by plant part	Low PPM	High PPM	StdDev	^*Reference
24	ALOE-EMODIN	Seed	--	--	--	*
Antibacterial MIC=2-64 ug/ml * Antiherpetic * Antileukemic * Antisalmonella Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp. Antiseptic MIC=2-64 ug/ml * Antistaphylococcic MIC=2-64 ug/ml * Antitumor 1 ug/mL * Antiviral * Arylamine-N-Acetyltransferase-Inhibitor * Calcium-Antagonist (strong activity) * Candidicide MIC=25-250 ug/ml * Cathartic Merck 11th Edition Cytotoxic 20 ppm * Estrogenic * Fungicide MIC=25-250 ug/ml * Genotoxic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Laxative * Mutagenic * Pesticide * Purgative ED50=>59.6 mg/kg orl mus * Termitifuge Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Topoisomerase-II-Inhibitor 1 mM Muller, S. O., Eckert, I., Lutz, W. K., Stopper, H. 1996. Genotoxicity of the Laxative Drug Components Emodin, Aloe-emodin and Danthron in Mammalian Cells: Topoisomerase II Mediated? Mutat Res, 371: 165-173. Topoisomerase-II-Inhibitor IC50=741 uM/ml Mueller, S. O., Stopper, H. 1999. Characterization of the Genotoxicity of Anthraquinones in Mammalian Cells. Biochimica & Biophysica Acta, 1428: 406-414. Tuberculostatic Pakistan Encyclopedia Planta Medica. 1986.
1	ANTHRONE	Seed	--	--	--	*
Emetic *
0	ASH	Sprout Seedling	--	99000.0	0.92	*
3	AURANTIOBTUSIN	Seed	--	--	--	*
Aldose-Reductase-Inhibitor IC50=13.6 uM * Antiaggregant * Estrogenic *
28	CALCIUM	Seed	--	11700.0	1.39	*
Antiallergic 500 mg/day * Antianxiety Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antiarrhythmic 500-1,500 mg * Antiarthritic 1,000 mg/day * Antiatherosclerotic 500 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Anticlimacteric 1,000-1,500 mg/day * Antidepressant Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antidote (Aluminum) Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antidote (Lead) Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antihyperkinetic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antihypertensive * Antiinsomniac Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antimenopausal 1,000-1,500 mg/day * Antiobesity * Antiosteoporotic 500-2,000 mg/day * Antiperiodontitic 750 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. AntiPMS 1 g/day * Antirheumatic 1,000 mg/day * Antistress 500-1,500 mg/day * Antitic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Anxiolytic 500-1,500 mg/day * Calcium-Channel-Blocker * Diuretic * Hypocholesterolemic 500 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Hypotensive 1 g/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Laxative 1,000-1,200 mg * Tranquilizer 500-1,500 mg/day * Vasodilator *
28	CALCIUM	Sprout Seedling	--	28100.0	2.61	*
Antiallergic 500 mg/day * Antianxiety Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antiarrhythmic 500-1,500 mg * Antiarthritic 1,000 mg/day * Antiatherosclerotic 500 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Anticlimacteric 1,000-1,500 mg/day * Antidepressant Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antidote (Aluminum) Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antidote (Lead) Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antihyperkinetic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antihypertensive * Antiinsomniac Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antimenopausal 1,000-1,500 mg/day * Antiobesity * Antiosteoporotic 500-2,000 mg/day * Antiperiodontitic 750 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. AntiPMS 1 g/day * Antirheumatic 1,000 mg/day * Antistress 500-1,500 mg/day * Antitic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Anxiolytic 500-1,500 mg/day * Calcium-Channel-Blocker * Diuretic * Hypocholesterolemic 500 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Hypotensive 1 g/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Laxative 1,000-1,200 mg * Tranquilizer 500-1,500 mg/day * Vasodilator *
0	CARBOHYDRATES	Sprout Seedling	--	726000.0	0.82	*
0	CAROTIN	Seed	--	--	--	*
1	CHRYSO-OBTUSIN	Seed	--	--	--	*
Antiaggregant *
2	CHRYSOPHANIC-ACID-9-ANTHRONE	Seed	--	--	--	*
Fungicide Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Pesticide *
10	CHRYSOPHANOL	Seed	--	--	--	*
Antibacterial Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155. Antiseptic * Calcium-Antagonist 5/6 aloeemodin * Candidicide Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155. Cathartic * Hemostat * Pesticide * Pigment Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Purgative ED50=>500 mg/kg orl mus * Termitifuge Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
0	CHRYSOPHANOL-1-BETA-GENTIOBIOSIDE	Seed	--	--	--	*
12	COPPER	Seed	8.0	10.0	-0.44	*
Antianemic * Antiarthritic * Antidiabetic 2-4 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antifatigue * Antiinflammatory Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antinociceptive Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antiosteoporotic * Cardioprotective * Contraceptive Martindale's 28th Hypocholesterolemic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Immunomodulator * Schizophrenigenic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
58	EMODIN	Seed	--	--	--	*
AGEs-Inhibitor IC50=118 uM * Aldose-Reductase-Inhibitor IC50=15.9 uM * Allergenic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp. Antiaggregant * Antiangiogenic * Antibacterial * Anticytomegalovirus ED50=1.1 ug/ml * Antifeedant Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Antiinflammatory 15 mg/kg * Antileukemic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antilymphomic * AntiMRSA MIC 2-64 ug/ml * Antimutagenic * Antineoplastic * Antiplaque ED50=1.1 ug/ml * Antiproliferant IC50=20-30 uM * Antisarcomic * Antiseptic * Antispasmodic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Antisprout * Antitumor (Breast) * Antiulcer 15 mg/kg * Antivaginitic TIllotson, A. K. (with Abel, Jr., R., Tillotson, N.H., Bajracharya, V.M.B.). 2001. The One Earth Herbal Sourcebook: Everything You Need to Know about Chinese, Western, and Ayurvedic Herbal Treatments. Twin Streams, Kensington Publishing Corp. NY,NY. 596 pp Antiviral ED50=1.1 ug/ml * Antiviral EC50=1.1 * Cathartic Merck 11th Edition CNS-Depressant 15 mg/kg ipr mus * Collagenase-Inhibitor IC50=40 uM * COX-2-Inhibitor * Cytotoxic CD50=2.6 ug/ml * Differentiator IC50=20-30 uM * Estrogenic * Genotoxic * Gonadotropic * Hypolipidemic * Immunostimulant * Immunosuppressant * iNOS-Inhibitor * Leucocytogenic * MMP-2-Inhibitor * MMP-7-Inhibitor * MMP-9-Inhibitor * Mutagenic * NO-Inhibitor IC50=60.7 uM * Pesticide * PGE2-Inhibitor * Prostaglandin-Synthesis-Inhibitor IC50=23 uM/ml Mueller, S. O., Stopper, H. 1999. Characterization of the Genotoxicity of Anthraquinones in Mammalian Cells. Biochimica & Biophysica Acta, 1428: 406-414. Protein-Kinase-C-Inhibitor IC50=25 uM * PTK-Inhibitor 10-100 uM * PTK-Inhibitor IC50=19-37 uM * Purgative ED50=>500 mg/kg orl mus * Styptic * Topoisomerase-II-Inhibitor 1 mM Muller, S. O., Eckert, I., Lutz, W. K., Stopper, H. 1996. Genotoxicity of the Laxative Drug Components Emodin, Aloe-emodin and Danthron in Mammalian Cells: Topoisomerase II Mediated? Mutat Res, 371: 165-173. Topoisomerase-II-Inhibitor IC50=7 uM/ml Mueller, S. O., Stopper, H. 1999. Characterization of the Genotoxicity of Anthraquinones in Mammalian Cells. Biochimica & Biophysica Acta, 1428: 406-414. Trichomonicide * Tyrosine-Kinase-Inhibitor * Vasodilator * Vasorelaxant *
0	FAT	Plant	--	44000.0	-0.11	*
0	FAT	Seed	33000.0	74000.0	-1.01	*
15	FIBER	Sprout Seedling	--	199000.0	1.24	*
Angiotensin-Receptor-Blocker * Antidiabetic * Antihypertensive * Antiobesity * Antitumor Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antiulcer Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Beta-Blocker * Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Cardioprotective * Diuretic * Hypocholesterolemic * Hypotensive 10 g/man/day/orl Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Hypouricemic * Laxative * Vasodilator *
7	GLUCOSE	Plant	--	--	--	*
Acetylcholinergic * Antiedemic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antihepatotoxic Merck 11th Edition Antiketotic Merck 11th Edition Antivaricose Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Hyperglycemic Merck 11th Edition Memory-Enhancer Science News, 138: 189, 1990.
6	IRON	Seed	--	50.0	-0.47	*
Antiakathisic Martindale's 29th Antianemic Martindale's 29th Anticanker * Anticheilitic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antimenorrhagic 100 mg/day/wmn/orl Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Prooxidant *
0	KAEMPFEROL-3-0-SOPHOROSIDE	Leaf	--	--	--	*

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^*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.

Plant Cassia tora (Fabaceae)

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