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Activities: 264
All Chemicals: 26
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Chemical Low PPM High PPM StdDev *Reference
16-HYDROXYINGENOL Plant-- -- *
3,4-DIOXYPHENYLALANINE Latex Exudate-- 5000.0 *
6,20-EPOXYLATHYROL-5,10-DIACETATE-3-PHENYLACETATE Plant-- -- *
7-HYDROXYLATHYROL Plant-- -- *
BETA-SITOSTEROL Leaf-- -- *
Activities (47)
Androgenic
Angiogenic
Anorexic Martindale's 28th
Antiadenomic Merck 11th Edition
Antiandrogenic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antibacterial Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155.
Anticancer (Breast) Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103.
Anticancer (Cervix)
Anticancer (Lung)
Antiedemic IC54=320 mg/kg orl
Antiestrogenic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antifeedant Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Antifertility Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antigonadotrophic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antihyperlipoproteinaemic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiinflammatory
Antileukemic
Antilymphomic
Antimutagenic 250 ug/ml
Antiophidic 2.3 mg musEconomic & Medicinal Plant Research, 5: 363.
Antioxidant IC44=10 uM
Antiprogestational Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antiprostaglandin 30 mg/day/12 wks
Antiprostatadenomic Merck 11th Edition
Antiprostatitic 10-20 mg 3 x/day/orl man
Antipyretic Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
Antitumor (Breast) Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103.
Antitumor (Cervix)
Antitumor (Lung)
Antiviral Abid Ali Khan, M.M., Jain, D.C., Bhakuni, R.S., Zaim, M., and Thakur, R.S. 1991. Occurrence of some antiviral sterols in Artemisia annua. Plant Science, 75: 161-165, 1991.
Apoptotic
Artemicide LC50=110 ppmJung, J.H., Pummangura, S., Chaichantipyuth, c., Patarapanich, C., and McLaughlin, J.L. 1989. Bioactive Constituents of Melodorum fruticosum. Phytochemistry. 29(5): 1667-1670. 1990.
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidicide Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155.
Caspase-8-Inducer
Estrogenic
Febrifuge Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
Gonadotrophic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Hepatoprotective
Hypocholesterolemic 2-6 g/man/day/orlMartindale's 30th
Hypocholesterolemic 9-3,330 mg/man/day/orlMartindale's 28th
Hypoglycemic Ivorra, M.D., Paya, M., and Villar, A. 1989. A Review of Natural Products and Plants as Potential Antidiabetic Drugs. Journal of Ethnopharmacology, 27: 243-275, 1989.
Hypolipidemic 2-6 g/day
Pesticide
Spermicide Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Ubiquiot Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Ulcerogenic 500 mg/kg ipr rat
BETULIN Plant-- -- *
Activities (13)
AntiHIV 6.1 uM
Anticarcinomic
Antifeedant
Antiflu
Antiinflammatory Recio, M., et al. 1994. Investigations on the Steroidal Anti-Inflammatory Activity of Triterpenoids from Diospyros leucomelas*. Planta Medica, 61: 9.
Antitumor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiviral 6.1 uM
Aphidifuge Lugemwa, F.N., Huang, F-Y., Bentley, M.D., Mendel, M.J., and Alford, A.R. 1990. A Heliothis zea Antifeedant from the Abundant Birchbark Triterpene Betulin. J. Agric. Food Chem. 38(2): 493-494.
Cytotoxic 600 ppm
Cytotoxic 8.6 uM
Hypolipemic
Prostaglandin-Synthesis-Inhibitor IC50=119 uMHuang, C., Tunon, H., Bohlin, L. 1995. Anti-Inflammatory Compounds Isolated from Menyanthes trifoliata L. Yao Hsueh Hsueh Pao, 30(8): 621-626.
Topoisomerase-II-Inhibitor IC50=38.6 uM
CAOUTCHOUC Latex Exudate-- -- *
DAPHNETIN Seed-- -- *
Activities (5)
Analgesic
Antibacterial Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Cholagogue
Immunostimulant
Pesticide
EUPHORBETIN Seed-- -- *
EUPHORBIASTEROID Seed-- -- *
FAT Seed400000.0 475000.0 1.1 *
FERULIC-ACID Leaf-- -- *
Activities (61)
Allelopathic Holappa, L.D., and Blum*, U. 1991. Effects of Exogenously Applied Ferulic Acid, a Potential Allelopathic Compound, on Leaf Growth, Water Utilization, and Endogenous Abscisic Acid Levels of Tomato, Cucumber, and Bean. J. of Chemical Ecology, 17(5): 865.
Analgesic Advance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 69.
Antiaggregant Ozaki, Y. and Ma, J-P. 1989. Inhibitory Effects of Tetramethylpyrazine and Ferulic Acid on Spontaneous Movement of Rat Uterus in Situ. Chem. Pharm. Bull. 38(6): 1620-1623, 1990.
Antiallergic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Antiarrhythmic
Antibacterial Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Anticancer (Colon)
Anticancer (Forestomach)
Anticancer (Liver)
Anticancer (Skin)
Anticarcinogenic
Antidysmenorrheic
Antiestrogenic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antihepatotoxic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiherpetic
Antiinflammatory Hagerman, A.E. Tannin-Protein Interactions. Phenolic Compounds in Food and Their Effects on Health, Ch.19.
Antileukemic IC50=25-56 ug/mlChiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antimitotic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antimutagenic Ki Soon Rhee. Oilseed Food Ingredients Used To Minimize Oxidative Flavor Deterioration in Meat Products. Phenolic Compounds in Food and Their Effects on Health, Ch.18.
Antineoplastic (Stomach)
Antinitrosaminic Ki Soon Rhee. Oilseed Food Ingredients Used To Minimize Oxidative Flavor Deterioration in Meat Products. Phenolic Compounds in Food and Their Effects on Health, Ch.18.
Antioxidant 3,000 uM
Antioxidant IC51=200 ppm
Antioxidant 1/3 quercetin
Antioxidant 1/2 BHA
Antioxidant EC50=9-15 ug/ml
Antiradicular EC50=9-15 ug/ml
Antiradicular IC50=116-124 uM
Antiserotonin Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antispasmodic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Antithrombic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Antitumor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antitumor (Colon)
Antitumor (Forestomach)
Antitumor (Liver)
Antitumor (Skin)
Antitumor-Promoter IC46=10 uMCancer Research, 48: 5941.
Antiviral Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
Arteriodilator Ozaki, Y. and Ma, J-P. 1989. Inhibitory Effects of Tetramethylpyrazine and Ferulic Acid on Spontaneous Movement of Rat Uterus in Situ. Chem. Pharm. Bull. 38(6): 1620-1623, 1990.
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidicide Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Cardiac Ozaki, Y. and Ma, J-P. 1989. Inhibitory Effects of Tetramethylpyrazine and Ferulic Acid on Spontaneous Movement of Rat Uterus in Situ. Chem. Pharm. Bull. 38(6): 1620-1623, 1990.
Cholagogue Pharmazie, 46: 156, 1991.
Choleretic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Fungicide Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Hepatoprotective Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
Hepatotropic
Herbicide Angewandte Botanik 68(5/6)=1994. Page 195.
Hydrocholerectic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Hypolipidemic
Immunostimulant Economic & Medicinal Plant Research, 1: 124.
Insectifuge Tunon, H., Thorsell, W., and Bohlin, L. 1993. Mosquito Repelling Activity of Compounds Occurring in Achillea millefolium L. (Asteraceae). Economic Botany 48(2): 111-120, 1994.
Metal-Chelator McEvily, A.J., Iyengar, R., and Gross, A.T. Inhibition of Polyphenol Oxidase by Phenolic Compounds. Phenolic Compounds in Food and Their Effects on Health, Ch.25.
Ornithine-Decarboxylase-Inhibitor Hagerman, A.E. Tannin-Protein Interactions. Phenolic Compounds in Food and Their Effects on Health, Ch.19.
Pesticide
Phagocytotic
Preservative Merck 11th Edition
Prostaglandigenic
Prostaglandin-Synthesis-Inhibitor 0.58-3.2 mMXu, L. N., Yu, W. G., Tian, J. Y., Liu, Q. Y. 1990. Effect of Sodium Ferulate on Arachidonic Acid Metabolism. Yao Hsueh Hsueh Pao, 25(6): 412-416.
Sunscreen Chemical Marketing Reporter; a weekly tabloid, 9/10/92.
Uterosedative 30-100 mg/kg ivn ratOzaki, Y. and Ma, J-P. 1989. Inhibitory Effects of Tetramethylpyrazine and Ferulic Acid on Spontaneous Movement of Rat Uterus in Situ. Chem. Pharm. Bull. 38(6): 1620-1623, 1990.
HENTRIACONTANE Stem-- -- *
INGENOL-3-HEXADECANIC-ACID-ESTER Plant-- -- *
KAEMPFEROL Leaf-- -- *
Activities (75)
11B-HSD-Inhibitor
5-Lipoxygenase-Inhibitor IC50 (uM)=20
Aldose-Reductase-Inhibitor 100 uMOliveira, T. T., Nagem, T. J., Miranda, L. C. G., Paula, V. F., Teixeira, M. A. 1997. Inhibitory Action on Aldose Reductase by Soybean Flavonoids. J Braz Chem Soc, 8(3): 211-213.
Antiaflatoxin IC50=8.73 uM
Antiaflatoxin IC50=3.28 ppm
Antiaggregant 30 uM
Antiallergic
Antibacterial 20 ug/ml
Anticancer
Antifertility 250 mg/kg/day/60 days/orl ratKumar, P., Dixit*, V.P., and Khanna, P. Antifertility Studies of Kaempferol: Isolation and Identification from Tissue Culture of some Medicinally Important Plant Species. Plantes medicinales et phytotherapie, 23: 193-201, 1989.
Antigingivitic 20 ug/ml
Antiherpetic 23-92 ug/mlAmoros, M., Simoes, C.M.O., Girre, L., et al. Synergistic Effect Of Flavones And Flavonols Against Herpes Simplex Virus Type 1 In Cell Culture. Comparison With The Antiviral Activity Of Propolis. J. of Natural Products 55(12):1732-1740, 1992.
Antihistaminic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Antiimplantation
Antiinflammatory 20 mg/kg
Antiinflammatory 200 mg/kg ipr rat
Antileukemic IC50=3.1 ug/mlLife Sciences 55: 1061.
Antilymphocytic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antimutagenic ID50=10-40 nMPhenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
Antioxidant IC50=40 uM
Antioxidant 3/4 quercetin
Antioxidant IC50=1.2 ug/ml
Antiperiodontic 20 ug/ml
Antiplaque 20 ug/ml
Antiradicular 7 x quercetin
Antiseptic 20 ug/ml
Antiserotonin 200 mg/kg ipr rat
Antispasmodic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Antistaphylococcic
Antitumor
Antitumor-Promoter Yasukawa, K., Takido, M., Takeuchi, M., Sato, Y., Nitta, K., and Nakagawa, S. 1989. Inhibitory Effects of Flavonol Glycosides on 12-O-Tetradecanoylphorbol-13-acetate-Induced Tumor Promotion. Chem. Pharm. Bull. 38(3): 774-776, 1990.
Antiulcer 50-200 mg/kg ipr rat
Antiviral 23-92 ug/ml
Apoptotic 60 uM
Aromatase-Inhibitor IC12=1 uM/lJournal of Medicinal Food 2: 235.1999.
COX-2-Inhibitor
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Carcinogenic Hutchings, A, Scott, AH, Lewis, G, and Cunningham, A. 1996. Zulu Medicinal Plants. An inventory. University of Natal Press, Pietermaritzburg. 450 pp.
Choleretic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Copper-Chelator
Cyclooxygenase-Inhibitor IC50 (uM) =20
Cytotoxic
Diaphoretic? Lawrence Review of Natural Products, Dec-90.
Diuretic
Estrogenic EC50=0.1-25 uM/lJournal of Medicinal Food 2: 227.1999.
Estrogenic EC50=0.56 uM
Fungicide 20 ug/mlFather Nature's Farmacy: The aggregate of all these three-letter citations.
HIV-RT-Inhibitor IC50=50-150 ug/mlGarcia, J., Morin,* C., Nyasse, B., Sondengam, B-L., Tchouankeu, J-C., and Tsamo, E. Complete Structural Assignments Of An Ergosterol Derivative From Entandrophragma utile. Journal of Natural Products, 54(1): 136-142, 1991.
Hepatoprotective IC50=5.46 uM
Hepatoprotective IC50=1.30 ppm
Hypotensive
ICAM-1-Inhibitor
Inotropic
Iodothyronine-Deiodinase-Inhibitor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
JNK-Inhibitor
Lipoxygenase-Inhibitor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
MAO-Inhibitor
Mutagenic
NO-Inhibitor IC50=13.9 uM
Natriuretic
Neuroprotective
PAF-Inhibitor
Pesticide
Protisticide Meckes, M., Calzada, F., Tapia-Contreras, A., Cedillo-Rivera, R. 1999. Antiprotozoal Properties of Helianthemum glomeratum. Phytotherapy Research, 13(2): 102-105.
Quinone-Reductase-Inducer 3 uM
TNF-alpha-Inhibitor IC50=3.99 uM
Teratologic
Topoisomerase-I-Inhibitor Santti, R., Makela, S., Strauss, L., Korman, J., Kostian, M. L. 1998. Phytoestrogens: Potential Endocrine Disruptors in Males. Toxicol Ind Health, 14: 223-237.
Topoisomerase-II-Inhibitor IC50=8.1 ug/mlConstantinou, A., Mehta, R., Runyan, C., Rao, K., Vaughan, A., Moon, R. 1995. Flavonoids as DNA Topoisomerase Antagonists and Poisons: Structure-Activity Relationships. J Natural Products, 58: 217-225.
Tyrosinase-Inhibitor ID50=230 uM
Uterotrophic EC50=0.1-25 uM/lJournal of Medicinal Food 2: 227.1999.
Vasodilator
cAMP-Phosphodiesterase-Inhibitor
iNOS-Inhibitor IC50=<15 uM
iNOS-Inhibitor IC50=13.9 uM
KAEMPFEROL-3-GLUCURONIDE Leaf-- -- *
L-DOPA Latex Exudate-- 17000.0 *
Activities (25)
Analgesic Martindale's 29th
Anorexic 50 mg/kg scu ratBorchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
Antidote (Manganese) Martindale's 29th
Antiencephalopathic Martindale's 29th
Antifeedant
Antimorphinic 100 scu musBorchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
Antineuroleptic Martindale's 29th
Antiparkinsonian 250-8,000 mg/man/day
Antireserpine ED50=400 orl musBorchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
Antitremor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Aphrodisiac Martindale's 29th
Arrhythmigenic Martindale's 29th
CNS-Active 50 ivn ratBorchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
Cardiovascular 12 ivn ratBorchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
Depressant Martindale's 29th
Diuretic 1-2 g/man/dayMartindale's 28th
Dopaminergic 225 orl mus
Dopaminergic 50 ipr ratBorchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
Emetic Martindale's 28th
Hallucinogen Martindale's 29th
Hypertensive Martindale's 29th
Hypotensive Martindale's 29th
Insectifuge Duke, J. A. Writeups or information summaries on approximately 2,000 economic plants, USDA, ARS, Beltsville, MD 20705.
Miotic Martindale's 29th
Natriuretic Martindale's 28th
LATHYROLS Seed-- -- *
OLEIC-ACID Seed340000.0 365500.0 2.03 *
Activities (18)
5-Alpha-Reductase-Inhibitor
Allergenic
Alpha-Reductase-Inhibitor
Anemiagenic
Antialopecic
Antiandrogenic
Antiinflammatory IC50=21 uM
Antileukotriene-D4 IC50=21 uM
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Choleretic 5 ml/man
Dermatitigenic
FLavor FEMA 1-30Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Hypocholesterolemic Spiller, G. A. 1996 (Spiller, G. A. Ed. 1996. CRC Handbook of Lipids in Human Nutrition. CRC Press. Boca Raton, FL. 233 pp.)
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Irritant Merck 11th Edition
Percutaneostimulant Seki, T., Toeda, C., Kawaguchi, T., Juni, K., Sugibayashi, K., and Morimoto, Y. 1990. Enhanced Transdermal Delivery of Zidovudine in Rats and Human Skin. Chem. Pharm. Bull. 38(11): 3086-3089, 1990.
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Propecic
P-COUMARIC-ACID Leaf-- -- *
Activities (25)
Aldose-Reductase-Inhibitor 4 ug/ml (weak activity)Ichikawa, K., et al. 1991. Isolation and Structure Determination of Aldose Reductase Inhibitors from Traditional Thai Medicine, and Syntheses of Their Derivatives. Sankyo Kenkyusho Nempo, 43: 99-110.
Allelopathic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antibacterial Pharmazie, 46: 156, 1991.
Anticlastogen
Antifertility
Antihepatotoxic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antileukemic IC50=25-56 ug/mlChiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antinitrosaminic Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Antioxidant IC24=30 ppm
Antioxidant 1/3 BHA
Antiperoxidant IC50=>100 uMPlanta Medica, 57: A54, 1991.
Antiseptic
Antispasmodic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Antitumor
Cancer-Preventive
Chemopreventive
Choleretic
Cytotoxic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Diaphoretic? Lawrence Review of Natural Products, Dec-90.
Fungicide Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Lipoxygenase-Inhibitor IC11=5 mMOszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690.
Pesticide
Prostaglandigenic
Prostaglandin-Synthesis-Inhibitor
Tyrosinase-Inhibitor ID50=3,650 uM
PROTEIN Seed-- 150000.0 -0.75 *
QUERCETIN Leaf-- -- *
Activities (176)
11B-HSD-Inhibitor
5-Lipoxygenase-Inhibitor IC50 (uM)=4
ATPase-Inhibitor Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Aldehyde-Oxidase-Inhibitor IC70-96=10 uM
Aldose-Reductase-Inhibitor 100 uM
Aldose-Reductase-Inhibitor 4 ug/mlIchikawa, K., et al. 1991. Isolation and Structure Determination of Aldose Reductase Inhibitors from Traditional Thai Medicine, and Syntheses of Their Derivatives. Sankyo Kenkyusho Nempo, 43: 99-110.
Aldose-Reductase-Inhibitor IC50=0.84 ug/ml cowOkada,Y,et al.1995.Search for Naturally Occurring Substances to Prevent the Complications of Diabetes.II.Inhibitory Effect of Coumarin and Flavonoid Derivatives on Bovine Lens Aldose Reductase and Rabbit Platelet Aggregation.Chem Pharm Bull43(8):1385-1387
Aldose-Reductase-Inhibitor IC50=0.344 uMMao, X. M., Zhang, J. Q. 1993. Inhibition of Aldose Reductase by Extracts of Chinese Herbal Medicine. Zhongguo Zhongyao Zazhi , 18(10): 623-624.
Allelochemic IC82=1 mMLydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Allergenic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Analgesic
AntiCrohn's 400 mg/man/3x/dayPizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
AntiGTF ID50=120 ug/ml
AntiHIV
AntiPMS 500 mg/2x/day/wmnPizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiaflatoxin IC50=25 uM
Antiaflatoxin IC50=7.5 ppm
Antiaggregant IC50=55 uMEconomic & Medicinal Plant Research, 5: 333.
Antiaggregant 30 uM
Antiaging
Antiallergic IC50=14 uMJim Duke's personal files.
Antialzheimeran
Antianaphylactic Meli, R., Autore, G., Di Carlo, G., Capasso, F. Inhibitory Action of Quercetin on Intestinal Transit in Mice. Phytotherapy Research 4(5): 201, 1990.
Antiangiogenic
Antiarthritic
Antiasthmatic IC50=14 uM
Antiatherosclerotic
Antibacterial Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Anticarcinomic (Breast) IC50=1.5 uMMedline (post 1990 searches filed in my computer)
Anticariogenic ID50=120 ug/ml
Anticataract
Anticolitic 400 mg/man/3x/dayPizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Anticomplementary
Anticystitic 1,000 mg/day/4 weeks
Antidepressant
Antidermatitic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antidiabetic
Antielastase IC50=0.8 ug/ml
Antiencephalitic Economic & Medicinal Plant Research, 5: 199.
Antiescherichic
Antiestrogenic
Antifeedant IC52=<1,000 ppm dietLydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Antifibrosarcomic
Antiflu Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
Antigastric Rastitel'nye Resursy, 21: 85.
Antigonadotropic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antihepatotoxic Joyeux, M., Rolland, A., Fleurentin, J., Mortier, F., and Dorfman, P. 1989. Tert-Butyl Hydroperoxide-Induced Injury in Isolated Rat Hepatocytes: A Model for Studying Anti-Hepatotoxic Crude Drugs. Planta Medica 56(2): 171-173, 1990.
Antiherpetic 48-150 ug/ml
Antihistaminic IC50=<10 uM
Antihydrophobic Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
Antihypertensive Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Antiinflammatory 20-150 mg/kgFitoterapia No.5-1990.
Antileishmanic IC50=64
Antileukemic IC50=10 uMEconomic & Medicinal Plant Research, 5: 225.
Antileukemic IC50=>10 ug/mlLife Sciences 55: 1061.
Antileukemic 5.5-60 uM
Antileukotriene Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antilipoperoxidant IC67=50
Antimalarial IC50=1-6.4 ug/mlMedicinal and Poisonous Plants of the Tropics. Leeuwenberg, A.J.M., ed. Pudoc, Wageningen. 1987.
Antimelanomic
Antimetastatic
Antimutagenic ID50=2-5 nMPhenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
Antimutagenic ID50=0.62 ug/ml
Antimyocarditic Economic & Medicinal Plant Research, 5: 199.
Antinitrosaminic
Antinociceptive
Antioxidant IC96=300 ppmPhenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
Antioxidant ED50=2.3 uMSeidel, V., Verholle, M., Malard, Y., Tillequin, F., Fruchart, J-C., Duriez, P., Bailleul, F., Teissier, E. 2000. Phenylpropanoids from Ballota nigra L. Inhibit in vitro LDL Peroxidation. Phytotherapy Research, 14(2): 93-98.
Antioxidant 4.7 x Vit. E
Antioxidant IC47=10 uM
Antipancreatitic Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Antiperiodontal Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiperistaltic
Antipermeability
Antiperoxidant Planta Medica, 57: A110, 1991.
Antipharyngitic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiplaque Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiplasmodial IC50=13-64
Antipodriac
Antipolio Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiproliferant 10 nM
Antiprostanoid
Antiprostatitic Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Antipsoriac Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiradicular IC50=4.6 uMPlanta Medica, 56(6): 695, 1990.
Antispasmodic
Antistreptococcic ID50=120 ug/ml
Antithiamin Phenolic Compounds in Food and Their Effects on Health, 69.
Antithrombic
Antitrypanosomic IC50=13
Antitumor 10 uM
Antitumor (Bladder)
Antitumor (Breast)
Antitumor (Colon)
Antitumor (Lung)
Antitumor (Ovary)
Antitumor (Skin) 20 uM
Antitumor-Promoter Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiulcer
Antiviral IC50=10 uMEconomic & Medicinal Plant Research, 5: 225.
Antiviral 48-150 ug/mlAmoros, M., Simoes, C.M.O., Girre, L., et al. Synergistic Effect Of Flavones And Flavonols Against Herpes Simplex Virus Type 1 In Cell Culture. Comparison With The Antiviral Activity Of Propolis. J. of Natural Products 55(12):1732-1740, 1992.
Apoptotic 20-60 uM
Bacteristat 10 mg/ml
Bradycardiac Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
COMT-Inhibitor
COX-2-Inhibitor <40 uM
Calmodulin-Antagonist Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidicide
Capillariprotective Merck 11th Edition
Carcinogenic 40,000 ppm (diet) musNigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Catabolic
Copper-Chelator
Cyclooxygenase-Inhibitor
Cytochrome-P450-1A2-Inhibitor
Cytotoxic ED50=70 ug/mlMatsukawa, Y., et al. The Effect of Quercetin and Other Flavonoids on Cell Cycle Progresssion and Growth of Human Gastric Cancer Cells. Planta Medica, 56(6): 677, 1990.
Cytotoxic IC82=100 ug/mlPlanta Medica, 57: A113, 1991.
Deiodinase-Inhibitor Jim Duke's personal files.
Diaphoretic? Lawrence Review of Natural Products, Dec-90.
Differentiator 5.5 uM
Estrogenic 10% genistein
Fungicide
Glucosyl-Transferase-Inhibitor ID50=120 ug/ml
HIV-RT-Inhibitor IC50=<1 ug/mlNakane, H., Fukushima, M., and Ono*, K. Differential Inhibition Of Reverse Transcriptase And Various DNA Polymerases By Digallic Acid And Its Derivatives. Journal of Natural Products, 53(5): 1234-1240, 1990.
Hemostat Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Hepatomagenic 5,000 ppm (diet) ratPhenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
Hepatoprotective
Hypoglycemic 100 mg/kg orl ratIvorra, M.D., Paya, M., and Villar, A. 1989. A Review of Natural Products and Plants as Potential Antidiabetic Drugs. Journal of Ethnopharmacology, 27: 243-275, 1989.
Inotropic
Insulinogenic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Juvabional Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Larvistat 8,000 ppm dietLydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Lipoxygenase-Inhibitor IC11=1.25 mMOszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690.
Lipoxygenase-Inhibitor IC50=0.1-5 uM
MAO-A-Inhibitor
MMP-9-Inhibitor 20 uM
Mast-Cell-Stabilizer
Metal-Chelator (Copper) Seidel, V., Verholle, M., Malard, Y., Tillequin, F., Fruchart, J-C., Duriez, P., Bailleul, F., Teissier, E. 2000. Phenylpropanoids from Ballota nigra L. Inhibit in vitro LDL Peroxidation. Phytotherapy Research, 14(2): 93-98.
Metalloproteinase-Inhibitor IC50=>42 uM
Mutagenic
NADH-Oxidase-Inhibitor
NEP-Inhibitor IC50=>42 uM
NF-kB-Inhibitor
NO-Inhibitor IC>50=125 uM
NO-Inhibitor IC50=20 uM
NO-Synthase-Inhibitor 5-50 uM
Neuroprotective 5-25 uM
Ornithine-Decarboxylase-Inhibitor <10 uM
P450-Inducer 5 uMFather Nature's Farmacy: The aggregate of all these three-letter citations.
P450-Inhibitor 50-100 uMFather Nature's Farmacy: The aggregate of all these three-letter citations.
PGE2-Inhibitor
PTK-Inhibitor 0.4-24 uM
Pesticide
Phospholipase-Inhibitor
Plasmodicide Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
Proliferant
Prostaglandin-Synthesis-Inhibitor 40 ug/mlIbewuike, J. C., Ogungbamila, F. O., Ogundaini, A. O., Okeke, I. N., Bohlin, L. 1997. Antiinflammatory and Antibacterial Activities of C-methylflavonol from Piliostigma thonningii. Phytotherapy Research, 11(4): 281-284.
Protein-Kinase-C-Inhibitor Naim, M., Zehavi, U., Nagy, S., and Rouseff, R.L. Hydroxycinnamic Acids as Off-Flavor Precursors in Citrus Fruits and Their Products. Phenolic Compounds in Food and Their Effects on Health, Ch.14.
Quinone-Reductase-Inducer 6 uMUda, Y., Price, K. R., Williamson, G., Rhodes, M. J. C. 1997. Induction of the Anticarcinogenic Marker Enzyme, Quinone Reductase, in Murine Hepatoma Cells In Vitro by Flavonoids. Cancer Lett., 120 (2): 213-216.
Quinone-Reductase-Inducer 13 uM
TNF-alpha-Inhibitor IC50=3.11 uM
Teratologic
Topoisomerase-I-Inhibitor IC50=12.8 ug/ml
Topoisomerase-I-Inhibitor IC50=42 uM
Topoisomerase-II-Inhibitor IC50=1-6.9 ug/ml
Topoisomerase-II-Inhibitor IC50=23-40 uM
Tumorigenic 0.1% diet orl rat/yrJim Duke's personal files.
Tyrosinase-Inhibitor ID50=70 uM
Tyrosine-Kinase-Inhibitor Economic & Medicinal Plant Research, 6: 170.
VEGF-Inhibitor
Vasodilator
Xanthine-Oxidase-Inhibitor IC50=>0.4 ug/mlChem. & Pharm. Bull. 38: 1772.
Xanthine-Oxidase-Inhibitor IC50=10.6 ug/ml
Xanthine-Oxidase-Inhibitor 3.1 uM
cAMP-Phosphodiesterase-Inhibitor Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
iNOS-Inhibitor IC50=20 uM
QUERCETIN-3-BETA-D-GLUCURONIDE Leaf-- -- *
TARAXEROL Stem-- -- *
Activities (2)
Antisecretory Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiulcer Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
TARAXERONE Stem-- -- *
WAX Leaf-- 2000.0 -0.9 *
*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.