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Activities: 374
All Chemicals: 135
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Chemical Low PPM High PPM StdDev *Reference
1-PENTADECENE Root-- -- Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Activities (1)
Antitumor
2-METHYLTETRADECA-5,12-DIENE Root-- -- Jim Duke's personal files.
2-METHYLTETRADECA-6,12-DIENE Root-- -- Jim Duke's personal files.
3,4-EPOXY-TRIDECA-1,5-DIENE-7,9,11-TRIYNE Stem-- 100.0 Jim Duke's personal files.
3,4-EPOXY-TRIDECA-1,5-DIENE-7,9,11-TRIYNE Flower-- -- Jim Duke's personal files.
3,4-EPOXY-TRIDECA-1,5-DIENE-7,9,11-TRIYNE Root8000.0 10000.0 -1.0 Jim Duke's personal files.
8-HYDROXY-PENTADEC-TRANS-9-ENE-11,13-DIYN-2-ONE Root-- -- Jim Duke's personal files.
8-HYDROXY-PENTADECA-TRANS-9-EN-11,13-DIYN-2-ONE Root-- -- Jim Duke's personal files.
ALKANES(C10-C33) Leaf-- -- Jim Duke's personal files.
ALKYLAMIDES Root-- -- Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
APIGENIN Leaf-- -- Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Activities (101)
11B-HSD-Inhibitor
AntiADD
AntiHIV IC72=200 ug/ml
AntiHIV IC50=143 ug/ml
Antiaflatoxin IC50=9.52 uM
Antiaflatoxin IC50=2.57 ppm
Antiaggregant
Antiaging
Antiallergic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiangiogenic 4 uM
Antiarrhythmic
Antibacterial Recio, M. C., Rios, J. L., and Villar, A., A review of some antimicrobial compounds isolated from medicinal plants reported in the literature 1978-1988, Phytotherapy Research, 3(4), 1989, 117-125.
Anticancer (Lung)
Anticomplementary
Antidermatitic Bisset, N.G., ed. 1994. Herbal Drugs and Phytopharmaceuticals. CRC Press. Boca Raton, FL. 566 pp.
Antiestrogenic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiherpetic 20-54 ug/ml
Antihistaminic IC50=10-35 uM
Antiinflammatory #NAME?
Antiinflammatory IC~65=1,000 uM
Antileukemic 20-50 uM
Antimelanomic 1-50 uM
Antimetastatic 1-50 uM
Antimutagenic ID50=10-40 nMPhenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
Antimutagenic ID50=0.55 ug/ml
Antioxidant 1.5 x Vit. E
Antioxidant IC28.5=62.5 ug/ml
Antiperistaltic
Antiproliferant 1-50 uM
Antiproliferant IC50=155 uM
Antispasmodic EC50=1-5 uM
Antistress 10 mg/kg
Antithyroid Jim Duke's personal files.
Antitumor 1-50 uM
Antitumor (Breast) 1-50 uM
Antitumor (Lung)
Antitumor (Skin)
Antiviral 20-54 ug/ml
Anxiolytic 10 mg/kg
Apoptotic 12-60 uM
Aromatase-Inhibitor IC65=1 uM/lJournal of Medicinal Food 2: 235.1999.
Beta-Glucuronidase-Inhibitor IC50=~40 uM
CNS-Depressant
COX-1-Inhibitor IC65=1,000 uM
COX-2-Inhibitor IC>65=1,000 uM
COX-2-Inhibitor <40 uM
COX-2-Inhibitor IC50=<15 uM
Calcium-Antagonist? Biochimica & Biophysica Acta, 1115: 69, 1991.
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Choleretic
Cyclooxygenase-Inhibitor
Cytochrome-P450-1A1-Inhibitor
Cytotoxic IC88=10 ug/mlPlanta Medica, 57: A113, 1991.
Cytotoxic 1-50 uM
Cytotoxic IC50=9.5 uM
DNA-Protective
Deiodinase-Inhibitor Jim Duke's personal files.
Differentiator MIC=30 uM
Differentiator IC40=40 uM
Diuretic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Estrogenic EC50=0.1-25 uM/lJournal of Medicinal Food 2: 227.1999.
Estrogenic 16% genistein
Estrogenic EC50=1 uM
HIF-1alpha-Inhibitor
Hyaluronidase-Inhibitor IC50+=50-250 uM
Hypotensive Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
ICAM-1-Inhibitor
IKK-Inhibitor
Inotropic
Interleukin-6-Inhibitor
MAO-Inhibitor
MAPK-Inhibitor
Musculotropic Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
Mutagenic
Myorelaxant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
NADH-Oxidase-Inhibitor
NF-kB-Inhibitor
NO-Synthase-Inhibitor 5-50 uM
Nodulation-Signal Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Ornithine-Decarboxylase-Inhibitor
P21-Inducer 10-70 uM
PKC-Inhibitor IC50=10 uM
PTK-Inhibitor 10-100 uM
Pesticide
Polyamine-Synthesis-Inhibitor
Progestational
Protein-Kinase-C-Inhibitor IC50=10-40 uM
Quinone-Reductase-Inducer 20 uMUda, Y., Price, K. R., Williamson, G., Rhodes, M. J. C. 1997. Induction of the Anticarcinogenic Marker Enzyme, Quinone Reductase, in Murine Hepatoma Cells In Vitro by Flavonoids. Cancer Lett., 120 (2): 213-216.
Radioprotective
Sedative 30-100 mg/kg
Sunscreen
TNF-alpha-Inhibitor IC50=3.27 uM
Topoisomerase-I-Inhibitor Santti, R., Makela, S., Strauss, L., Korman, J., Kostian, M. L. 1998. Phytoestrogens: Potential Endocrine Disruptors in Males. Toxicol Ind Health, 14: 223-237.
Topoisomerase-II-Inhibitor 50 ug/mlAzuma, Y., Onishi, Y., Sato, Y., Kizaki, H. 1995. Effects of Protein Tyrosine Kinase Inhibitors With Different Modes of Action on Topoisomerase Activity and Death of IL-2-Dependent CTLL-2-Cells. J Biochemistry, 118: 312-318.
Topoisomerase-II-Inhibitor IC28=18 uM
Topoisomerase-II-Inhibitor IC45=180 uM
Uterotrophic EC50=0.1-25 uM/lJournal of Medicinal Food 2: 227.1999.
VEGF-Inhibitor IC50=2-7 uM
Vasodilator
Xanthine-Oxidase-Inhibitor 0.36 uM
iNOS-Inhibitor IC50=<15 uM
BEHENIC-ACID-ETHYL-ESTER Root-- -- Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
BETA-SITOSTEROL Root-- -- *
Activities (47)
Androgenic
Angiogenic
Anorexic Martindale's 28th
Antiadenomic Merck 11th Edition
Antiandrogenic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antibacterial Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155.
Anticancer (Breast) Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103.
Anticancer (Cervix)
Anticancer (Lung)
Antiedemic IC54=320 mg/kg orl
Antiestrogenic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antifeedant Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Antifertility Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antigonadotrophic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antihyperlipoproteinaemic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiinflammatory
Antileukemic
Antilymphomic
Antimutagenic 250 ug/ml
Antiophidic 2.3 mg musEconomic & Medicinal Plant Research, 5: 363.
Antioxidant IC44=10 uM
Antiprogestational Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antiprostaglandin 30 mg/day/12 wks
Antiprostatadenomic Merck 11th Edition
Antiprostatitic 10-20 mg 3 x/day/orl man
Antipyretic Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
Antitumor (Breast) Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103.
Antitumor (Cervix)
Antitumor (Lung)
Antiviral Abid Ali Khan, M.M., Jain, D.C., Bhakuni, R.S., Zaim, M., and Thakur, R.S. 1991. Occurrence of some antiviral sterols in Artemisia annua. Plant Science, 75: 161-165, 1991.
Apoptotic
Artemicide LC50=110 ppmJung, J.H., Pummangura, S., Chaichantipyuth, c., Patarapanich, C., and McLaughlin, J.L. 1989. Bioactive Constituents of Melodorum fruticosum. Phytochemistry. 29(5): 1667-1670. 1990.
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidicide Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155.
Caspase-8-Inducer
Estrogenic
Febrifuge Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
Gonadotrophic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Hepatoprotective
Hypocholesterolemic 2-6 g/man/day/orlMartindale's 30th
Hypocholesterolemic 9-3,330 mg/man/day/orlMartindale's 28th
Hypoglycemic Ivorra, M.D., Paya, M., and Villar, A. 1989. A Review of Natural Products and Plants as Potential Antidiabetic Drugs. Journal of Ethnopharmacology, 27: 243-275, 1989.
Hypolipidemic 2-6 g/day
Pesticide
Spermicide Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Ubiquiot Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Ulcerogenic 500 mg/kg ipr rat
BETAINE Root-- 1000.0 -0.29 Jim Duke's personal files.
Activities (14)
Abortifacient
Antigastritic Martindale's 29th
Antihomocystinuric
Antimyoatrophic
Bruchiphobe Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Cardioprotective
Diuretic Wealth of India.
Emmenagogue Wealth of India.
Ethanolytic
Expectorant
Hepatoprotective
Lipotropic
Mucogenic
Pesticide
BORNEOL Shoot-- -- Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Activities (35)
(-)-Chronotropic 29 ug/mlHansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
(-)-Inotropic 29 ug/mlHansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
Allelochemic
Analgesic
Antiacetylcholine Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Antibacterial MIC=125-250 ug/ml
Antibronchitic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiescherichic MIC=125 ug/ml
Antifeedant
Antiinflammatory
Antiotitic
Antipyretic
Antisalmonella MIC=125 ug/ml
Antispasmodic ED50=0.008 mg/ml
Antistaphylococcic MIC=250 ug/ml
Antiyeast MIC=250 ug/ml
CNS-Stimulant List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
CNS-Toxic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Candidicide MIC=250 ug/ml
Choleretic
FLavor FEMA<1Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide
Hepatoprotective
Herbicide IC50=470 mMLydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Herbicide IC50=470 uMKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Inhalant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Insect-Repellent
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Irritant Rinzler, C. A. 1990. The Complete Book of Herbs, Spices and Condiments. Facts on File, New York. 199 pp.
Myorelaxant Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Nematicide MLC=1 mg/mlShoyakugaku Zasshi, 44: 183.
Perfumery Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
Sedative Medline (post 1990 searches filed in my computer)
Tranquilizer
BORNYL-ACETATE Shoot-- -- Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Activities (12)
(-)-Chronotropic 933 nl/mlHansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
(-)-Inotropic 933 nl/mlHansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
Antibacterial Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Antifeedant Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Antispasmodic ED50=0.09 mg/mlFitoterapia No.59-1984.
Antiviral Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Expectorant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
FLavor FEMA 70-80Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Insectifuge Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin.
Myorelaxant Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Pesticide
Sedative
CAFTARIC-ACID Root-- -- Jim Duke's personal files.
Activities (3)
Antiotitic
Bacteristat
Hyaluronidase-Inhibitor
CARYOPHYLLENE Shoot-- -- Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Activities (31)
Aldose-Reductase-Inhibitor
Allergenic
Analgesic Taylor, Leslie. 2005. The Healing Power of Rainforest Herbs. SquareOne Publisher, Garden City Park, NY. 519 pp.
Antiacne
Antiasthmatic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Antibacterial
Anticariogenic MIC=>1,600 ug/mlMuroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105.
Antidermatitic
Antiedemic Shimizu,*M., et al. 1990. Anti-inflammatory Constituents of Topically Applied Crude Drugs. IV.1) Constituents and Anti-inflammatory Effect of Paraguayan Crude Drug 'Alhucema' (Lavandula latifolia Vill.)2). Chem. Pharm. Bull. 38(8): 2283-2284, 1990.
Antifeedant 500 ppmKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Antiinflammatory IC50=100 uMShimizu,*M., et al. 1990. Anti-inflammatory Constituents of Topically Applied Crude Drugs. IV.1) Constituents and Anti-inflammatory Effect of Paraguayan Crude Drug 'Alhucema' (Lavandula latifolia Vill.)2). Chem. Pharm. Bull. 38(8): 2283-2284, 1990.
Antileishmanic
Antionychyotic Taylor, Leslie. 2005. The Healing Power of Rainforest Herbs. SquareOne Publisher, Garden City Park, NY. 519 pp.
Antiproliferant
Antispasmodic
Antistaphylococcic
Antistreptococcic
Antitumor Zheng, G-Q., Kenney, P.M., and Lam, L.K.T. Sesquiterpenes From Clove (Eugenia caryophyllata) As Potential Anticarcinogenic Agents. Journal of Natural Products 55(7): 999-1003, 1992.
Antiulcer Taylor, Leslie. 2005. The Healing Power of Rainforest Herbs. SquareOne Publisher, Garden City Park, NY. 519 pp.
Candidicide
FLavor FEMA 20-200Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide
Gastroprotective Taylor, Leslie. 2005. The Healing Power of Rainforest Herbs. SquareOne Publisher, Garden City Park, NY. 519 pp.
Insectifuge
Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Larvicide
Mosquitocide
Perfumery Merck 11th Edition
Pesticide
Sedative
Termitifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
CARYOPHYLLENE-EPOXIDE Shoot-- -- Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Activities (6)
Antifeedant 1 mM (diet)Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Attifuge CIBA (Chadwick, D.J. and Marsh, J. 1990. Bioactive Compounds from Plants. CIBA Foundation Symposium 154. John Wiley & Sons, Ltd. Chichester UK. 242 pp.
Fungistat CIBA (Chadwick, D.J. and Marsh, J. 1990. Bioactive Compounds from Plants. CIBA Foundation Symposium 154. John Wiley & Sons, Ltd. Chichester UK. 242 pp.
Insectifuge CIBA (Chadwick, D.J. and Marsh, J. 1990. Bioactive Compounds from Plants. CIBA Foundation Symposium 154. John Wiley & Sons, Ltd. Chichester UK. 242 pp.
Larvicide IC60=5 mMLydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Pesticide
CEROTIC-ACID Root-- -- *
CHICHORIC-ACID Flower-- -- Jim Duke's personal files.
CHICHORIC-ACID Leaf-- -- Jim Duke's personal files.
CHICHORIC-ACID Stem-- -- Jim Duke's personal files.
CHICHORIC-ACID Root-- -- Jim Duke's personal files.
CHICHORIC-ACID-DIMETHYL-ETHER Flower-- -- Jim Duke's personal files.
CHICHORIC-ACID-DIMETHYL-ETHER Leaf-- -- Jim Duke's personal files.
CHICHORIC-ACID-DIMETHYL-ETHER Stem-- -- Jim Duke's personal files.
CHICHORIC-ACID-DIMETHYL-ETHER Root-- -- Jim Duke's personal files.
CHICHORIC-ACID-MONOMETHYL-ETHER Flower-- -- Jim Duke's personal files.
CHICHORIC-ACID-MONOMETHYL-ETHER Leaf-- -- Jim Duke's personal files.
CHICHORIC-ACID-MONOMETHYL-ETHER Stem-- -- Jim Duke's personal files.
CHICHORIC-ACID-MONOMETHYL-ETHER Root-- -- Jim Duke's personal files.
CHICORIC-ACID Root-- -- Jim Duke's personal files.
Activities (10)
AntiHIV
AntiHIV-Integrase
Antiflu Economic & Medicinal Plant Research, 5: 207.
Antiradicular
Antistomatitic Economic & Medicinal Plant Research, 5: 194.
Antisunburn IC87=20 uM
Antiviral IC50=125 ug/mlEconomic & Medicinal Plant Research, 5: 253.
Immunostimulant 10-100 ug/ml
Pesticide
Phagocytotic 10-100 ug/ml
CHLOROGENIC-ACID Leaf-- -- Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Activities (77)
Aldose-Reductase-Inhibitor IC50=1.8 uM rat (strong activity)Yoshikawa, M., et al. 1999. Medicinal Flowers. I. Aldose Reductase Inhibitors and Three New Eudesmane-Type Sesquiterpenes, Kikkanols A, B, and C, From the Flowers of Chrysanthemum inducum L. Chem Pharm Bull, 47(3): 340-345.
Allelochemic
Allergenic
Analgesic
AntiEBV Economic & Medicinal Plant Research, 6: 189.
AntiHIV Economic & Medicinal Plant Research, 6: 189.
AntiLegionella
Antiatherosclerotic
Antibacterial
Anticancer (Colon)
Anticancer (Forestomach)
Anticancer (Liver)
Anticancer (Skin)
Anticarcinogenic
Antidiabetic
Antifeedant
Antigenotoxic
Antigonadotropic Jim Duke's personal files.
Antihemolytic 10 uMOhnishi, M., Morishita, H., Iwahashi, H., Toda, S., Shirataki, Y., Kimura, M., and Kido, R. 1993. Inhibitory Effects of Chlorogenic Acids on Linoleic Acid Peroxidation and Haemolysis. Phytochemistry. 36(3): 579-583. 1994.
Antihepatotoxic
Antiherpetic Economic & Medicinal Plant Research, 5: 194.
Antihistaminic
Antihypercholesterolemic Economic & Medicinal Plant Research, 6: 189.
Antihyperthyroid
Antiinflammatory Hagerman, A.E. Tannin-Protein Interactions. Phenolic Compounds in Food and Their Effects on Health, Ch.19.
Antileukotriene
Antimelanogenic
Antimutagenic
Antinitrosaminic
Antioxidant IC53=200 ppmHuang, M-T., and Ferraro, T. Phenolic Compounds in Food and Cancer Prevention. Phenolic Compounds in Food and Their Effects on Health, Ch.2 p.21.
Antioxidant IC80=12 uM
Antioxidant IC50=54.2 uM
Antiperoxidant IC50=36 uMPlanta Medica, 57: A54, 1991.
Antipolio Jim Duke's personal files.
Antiradicular 10 uMOhnishi, M., Morishita, H., Iwahashi, H., Toda, S., Shirataki, Y., Kimura, M., and Kido, R. 1993. Inhibitory Effects of Chlorogenic Acids on Linoleic Acid Peroxidation and Haemolysis. Phytochemistry. 36(3): 579-583. 1994.
Antiradicular 9 x quercetin
Antiseptic
Antisunburn
Antithyroid Jim Duke's personal files.
Antitumor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antitumor (Colon)
Antitumor (Forestomach)
Antitumor (Liver)
Antitumor (Skin)
Antitumor-Promoter IC25=10 uM
Antiulcer Economic & Medicinal Plant Research, 6: 189.
Antiviral Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
Autotoxic
CNS-Active Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
CNS-Stimulant 1/6 Caffeine
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Cardioprotective
Chemopreventive
Cholagogue Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
Choleretic Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Clastogenic Friedman, M. and Dao, L. 1990. Effect of Autoclaving and Conventional and Microwave Baking on the Ergot Alkaloid and Chlorogenic Acid Contents of Morning Glory (Ipomoea tricolor Cav. cv.) Heavenly Blue Seeds. J. Agric. Food Chem. 38: 805-808.
Collagen-Sparing
Diuretic
Fungicide Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Hepatoprotective Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Histamine-Inhibitor
Hypoglycemic
Immunostimulant
Insectifuge Tunon, H., Thorsell, W., and Bohlin, L. 1993. Mosquito Repelling Activity of Compounds Occurring in Achillea millefolium L. (Asteraceae). Economic Botany 48(2): 111-120, 1994.
Interferonogenic Economic & Medicinal Plant Research, 1: 124.
Juvabional Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Larvistat Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Leukotriene-Inhibitor
Lipoxygenase-Inhibitor IC23=5 mMOszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690.
Metal-Chelator McEvily, A.J., Iyengar, R., and Gross, A.T. Inhibition of Polyphenol Oxidase by Phenolic Compounds. Phenolic Compounds in Food and Their Effects on Health, Ch.25.
NO-Genic
Ornithine-Decarboxylase-Inhibitor Hagerman, A.E. Tannin-Protein Interactions. Phenolic Compounds in Food and Their Effects on Health, Ch.19.
Oviposition-Stimulant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
Sunscreen
Sweetener Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Vulnerary
CICHORIC-ACID Root-- -- Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Activities (14)
AntiHIV
AntiHIV-Integrase
Antiflu Economic & Medicinal Plant Research, 5: 207.
Antiotitic
Antiradicular
Antistomatitic Economic & Medicinal Plant Research, 5: 194.
Antisunburn IC87=20 uM
Antiviral IC50=125 ug/mlEconomic & Medicinal Plant Research, 5: 253.
Bacteristat
Collagen-Sparing IC87=20 uM
Hyaluronidase-Inhibitor
Immunostimulant 10-100 ug/ml
Pesticide
Phagocytotic 10-100 ug/ml
CYNARIN Root-- -- *
Activities (23)
Antibacterial
Antidyspeptic
Antilipolytic
Antistaphylococcic
Antistreptococcic
Antisunburn
CNS-Active Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
Cholagogue Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
Choleretic 200-250 mg/3x/dayMartindale's 28th
Cholesterolytic
Collagen-Sparing
Cytoprotective Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Diuretic Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
Hepatoprotective 100 mg/kg
Hepatoregenerative Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Hepatotonic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Hyperemic
Hypocholesterolemic 60-1,500 mg/man/day
Hypolipidemic 500 mg/2x/dayMartindale's 28th
Hypotriglyceridemic 60-1,500 mg/man/dayNewall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Lipolytic
Pesticide
Sweetener Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
DOCECA-2E,4E,8Z,10E/Z-TETRAENOIC-ACID-ISOBUTYLAMIDES Shoot-- -- Bisset, N.G., ed. 1994. Herbal Drugs and Phytopharmaceuticals. CRC Press. Boca Raton, FL. 566 pp.
DOCECA-2E,4E,8Z,10E/Z-TETRAENOIC-ACID-ISOBUTYLAMIDES Root-- -- Bisset, N.G., ed. 1994. Herbal Drugs and Phytopharmaceuticals. CRC Press. Boca Raton, FL. 566 pp.
DODECA-2,4,8,10-TETRAEN-1-OIC-ACID-ISOBUTYLAMIDE Root-- 298.5 1.0 Jim Duke's personal files.
DODECA-2,4-DIEN-1-YL-ISOVALERATE Root-- -- Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
DODECA-2-TRANS-4-CIS-10-CIS-TRIEN-8-YNOIC-ACID-ISOBUTYLAMIDE Root-- -- Jim Duke's personal files.
DODECA-2-TRANS-4-CIS-DIENE-8,10-DIYNOIC-ACID-ISOBUTYLAMIDE Shoot-- -- Jim Duke's personal files.
DODECA-2-TRANS-4-CIS-DIENE-8,10-DIYNOIC-ACID-ISOBUTYLAMIDE Root-- -- Jim Duke's personal files.
DODECA-2-TRANS-4-TRANS-10-CIS-TRIEN-8-YNOIC-ACID-ISOBUTYLAMIDE Shoot-- -- Jim Duke's personal files.
DODECA-2-TRANS-4-TRANS-8-CIS-10-CIS-TETRAENOIC-ACID-ISOBUTYLAMIDE Shoot-- -- Jim Duke's personal files.
DODECA-2-TRANS-4-TRANS-8-CIS-10-CIS-TETRAENOIC-ACID-ISOBUTYLAMIDE Root-- -- Jim Duke's personal files.
DODECA-2-TRANS-4-TRANS-8-CIS-10-TRANS-TETRAENOIC-ACID-ISOBUTYLAMIDE Shoot-- -- Jim Duke's personal files.
DODECA-2-TRANS-4-TRANS-8-CIS-10-TRANS-TETRAENOIC-ACID-ISOBUTYLAMIDE Root-- -- Jim Duke's personal files.
DODECA-2-TRANS-4-TRANS-8-CIS-TRIENOIC-ACID-ISOBUTYLAMIDE Shoot-- -- Jim Duke's personal files.
DODECA-2-TRANS-4-TRANS-DIENOIC-ACID-ISOBUTYLAMIDE Shoot-- -- Jim Duke's personal files.
DODECA-2-TRANS-4-TRANS-DIENOIC-ACID-ISOBUTYLAMIDE Root-- -- Jim Duke's personal files.
DODECA-2-TRANS-ENE-8,10-DIYNOIC-ACID-2-METHYL-BUTYLAMIDE Root-- -- Jim Duke's personal files.
DODECA-2-TRANS-ENE-8,10-DIYNOIC-ACID-ISOBUTYLAMIDE Root-- -- Jim Duke's personal files.
DODECA-CIS-2-TRANS-4-DIENE-8,10-DIYN-1-OIC-ACID-ISOBUTYLAMIDE Root-- 298.5 1.0 Jim Duke's personal files.
DODECA-TRANS-2-CIS-4-CIS-10-TRIEN-8-YNOIC-ACID-ISOBUTYLAMIDE Root-- 13.7 Jim Duke's personal files.
DODECA-TRANS-2-CIS-4-DIENE-8,10-DIYNOIC-ACID-ISOBUTYLAMIDE Root-- 6.8 1.0 Jim Duke's personal files.
DODECA-TRANS-2-ENE-8,10-DIYNOIC-ACID-2-METHYL-BUTYLAMIDE Root-- 6.8 Jim Duke's personal files.
DODECA-TRANS-2-ENE-8,10-DIYNOIC-ACID-ISOBUTYLAMIDE Root-- 241.3 Jim Duke's personal files.
DODECA-TRANS-2-TRANS-4-CIS-8-CIS-10-TETRAENOIC-ACID-ISOBUTYLAMIDE Root-- -- Jim Duke's personal files.
DODECA-TRANS-2-TRANS-4-CIS-8-TRANS-10-TETRAENOIC-ACID-ISOBUTYLAMIDE Root-- -- Jim Duke's personal files.
DODECA-TRANS-2-TRANS-4-DIENOIC-ACID-ISOBUTYLAMIDE Root-- 103.4 Jim Duke's personal files.
ECHINACEA-FACTOR-A Root-- -- Jim Duke's personal files.
ECHINACEA-FACTOR-B Root-- -- Jim Duke's personal files.
ECHINACEA-POLYSACCHARIDE Tissue Culture-- -- Jim Duke's personal files.
ECHINACEIN Root4.0 100.0 0.71 *
Activities (3)
Insecticide
Pesticide
Sialogogue
ECHINACIN-B Root-- -- Jim Duke's personal files.
Activities (1)
Vulnerary Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
ECHINACOSIDE Flower1000.0 10000.0 Bisset, N.G., ed. 1994. Herbal Drugs and Phytopharmaceuticals. CRC Press. Boca Raton, FL. 566 pp.
Activities (10)
Antibacterial Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
Antiflu Economic & Medicinal Plant Research, 5: 207.
Antihepatotoxic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antistaph
Antistomatitic Economic & Medicinal Plant Research, 5: 194.
Antisunburn IC90=20 uM
Antiviral
Collagen-Sparing IC90=20 uM
Immunostimulant
Pesticide
ECHINACOSIDE Root3000.0 13000.0 -1.41 *
Activities (10)
Antibacterial Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
Antiflu Economic & Medicinal Plant Research, 5: 207.
Antihepatotoxic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antistaph
Antistomatitic Economic & Medicinal Plant Research, 5: 194.
Antisunburn IC90=20 uM
Antiviral
Collagen-Sparing IC90=20 uM
Immunostimulant
Pesticide
ECHINACOSIDE-1 Root-- -- Jim Duke's personal files.
ECHINACOSIDE-2 Root-- -- Jim Duke's personal files.
ECHINOLONE Root-- 3.0 Jim Duke's personal files.
Activities (2)
Juvabional
Pesticide
EO Root400.0 13000.0 -0.04 *
FRUCTANS Root-- -- Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
GERMACRENE-D Shoot-- -- Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Activities (2)
Pesticide
Pheromone
GLYCINE-BETAINE Leaf-- 1130.0 -1.0 Jim Duke's personal files.
GLYCINE-BETAINE Flower-- 8050.0 -1.0 Jim Duke's personal files.
GLYCINE-BETAINE Root-- 3100.0 -1.0 Jim Duke's personal files.
GLYCINE-BETAINE Stem-- 4900.0 -1.0 Jim Duke's personal files.
HEXADECA-2-TRANS-9-CIS-DIENE-12,14-DIYNOIC-ACID-ISOBUTYLAMIDE Root-- -- Jim Duke's personal files.
HEXADECA-TRANS-2-CIS-9-DIENE-12,14-DIYNOIC-ACID-ISOBUTYLAMIDE Root-- 6.8 Jim Duke's personal files.
HYDROCARBONS Root Essent. Oil-- -- Jim Duke's personal files.
INULIN Root50000.0 90000.0 -0.9 *
Activities (19)
Alcohol-Dehydrogenase-Inhibitor (diagnostic)=50 mg/kg/ivn/manMartindale's 29th
Anticolitic?
Antidiabetic
Antidiarrheic
Antiobesity?
Antiosteoporotic?
Bifidogenic
Chemopreventive (Breast Cancer)
Chemopreventive (Colon Cancer)
Expectorant Pedersen, M. 1987. Nutritional Herbology. Pederson Publishing. Bountiful, Utah. 377 pp.
Gastrostimulant
Hypocholesterolemic
Hypoglycemic
Immunostimulant
Laxative
Lipolytic
Prebiotic
Probiotic
Probiotigenic
ISOBUTYLAMIDES Root90.0 1510.0 Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
ISOCHLOROGENIC-ACID Leaf-- -- Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Activities (4)
Antioxidant Phenolic Compounds in Food and Their Effects on Health, 64.
Antiseptic J. Nat. Prod. 46(5).
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Pesticide
ISORHAMNETIN Leaf-- -- Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Activities (11)
Antibacterial
Antihistaminic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Antiinflammatory Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Antioxidant Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Antispasmodic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Hepatoprotective Advance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 210.
MAO-Inhibitor
Pesticide
Quinone-Reductase-Inducer Yannai, S., Day, A. J., Williamson, G., Rhodes, M. J. C. 1998. Characterization of Flavonoids as Monofunctional or Bifunctional Inducers of Quinone Reductase in Murine Hepatoma Cell Lines. Food Chem Toxicol, 36(8): 623-630.
Vasodilator
ISOTUSSILAGIN Plant-- -- Jim Duke's personal files.
ISOTUSSILAGINE Root15.0 60.0 Bisset, N.G., ed. 1994. Herbal Drugs and Phytopharmaceuticals. CRC Press. Boca Raton, FL. 566 pp.
KAEMPFEROL Leaf-- -- Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Activities (75)
11B-HSD-Inhibitor
5-Lipoxygenase-Inhibitor IC50 (uM)=20
Aldose-Reductase-Inhibitor 100 uMOliveira, T. T., Nagem, T. J., Miranda, L. C. G., Paula, V. F., Teixeira, M. A. 1997. Inhibitory Action on Aldose Reductase by Soybean Flavonoids. J Braz Chem Soc, 8(3): 211-213.
Antiaflatoxin IC50=8.73 uM
Antiaflatoxin IC50=3.28 ppm
Antiaggregant 30 uM
Antiallergic
Antibacterial 20 ug/ml
Anticancer
Antifertility 250 mg/kg/day/60 days/orl ratKumar, P., Dixit*, V.P., and Khanna, P. Antifertility Studies of Kaempferol: Isolation and Identification from Tissue Culture of some Medicinally Important Plant Species. Plantes medicinales et phytotherapie, 23: 193-201, 1989.
Antigingivitic 20 ug/ml
Antiherpetic 23-92 ug/mlAmoros, M., Simoes, C.M.O., Girre, L., et al. Synergistic Effect Of Flavones And Flavonols Against Herpes Simplex Virus Type 1 In Cell Culture. Comparison With The Antiviral Activity Of Propolis. J. of Natural Products 55(12):1732-1740, 1992.
Antihistaminic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Antiimplantation
Antiinflammatory 20 mg/kg
Antiinflammatory 200 mg/kg ipr rat
Antileukemic IC50=3.1 ug/mlLife Sciences 55: 1061.
Antilymphocytic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antimutagenic ID50=10-40 nMPhenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
Antioxidant IC50=40 uM
Antioxidant 3/4 quercetin
Antioxidant IC50=1.2 ug/ml
Antiperiodontic 20 ug/ml
Antiplaque 20 ug/ml
Antiradicular 7 x quercetin
Antiseptic 20 ug/ml
Antiserotonin 200 mg/kg ipr rat
Antispasmodic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Antistaphylococcic
Antitumor
Antitumor-Promoter Yasukawa, K., Takido, M., Takeuchi, M., Sato, Y., Nitta, K., and Nakagawa, S. 1989. Inhibitory Effects of Flavonol Glycosides on 12-O-Tetradecanoylphorbol-13-acetate-Induced Tumor Promotion. Chem. Pharm. Bull. 38(3): 774-776, 1990.
Antiulcer 50-200 mg/kg ipr rat
Antiviral 23-92 ug/ml
Apoptotic 60 uM
Aromatase-Inhibitor IC12=1 uM/lJournal of Medicinal Food 2: 235.1999.
COX-2-Inhibitor
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Carcinogenic Hutchings, A, Scott, AH, Lewis, G, and Cunningham, A. 1996. Zulu Medicinal Plants. An inventory. University of Natal Press, Pietermaritzburg. 450 pp.
Choleretic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Copper-Chelator
Cyclooxygenase-Inhibitor IC50 (uM) =20
Cytotoxic
Diaphoretic? Lawrence Review of Natural Products, Dec-90.
Diuretic
Estrogenic EC50=0.1-25 uM/lJournal of Medicinal Food 2: 227.1999.
Estrogenic EC50=0.56 uM
Fungicide 20 ug/mlFather Nature's Farmacy: The aggregate of all these three-letter citations.
HIV-RT-Inhibitor IC50=50-150 ug/mlGarcia, J., Morin,* C., Nyasse, B., Sondengam, B-L., Tchouankeu, J-C., and Tsamo, E. Complete Structural Assignments Of An Ergosterol Derivative From Entandrophragma utile. Journal of Natural Products, 54(1): 136-142, 1991.
Hepatoprotective IC50=5.46 uM
Hepatoprotective IC50=1.30 ppm
Hypotensive
ICAM-1-Inhibitor
Inotropic
Iodothyronine-Deiodinase-Inhibitor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
JNK-Inhibitor
Lipoxygenase-Inhibitor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
MAO-Inhibitor
Mutagenic
NO-Inhibitor IC50=13.9 uM
Natriuretic
Neuroprotective
PAF-Inhibitor
Pesticide
Protisticide Meckes, M., Calzada, F., Tapia-Contreras, A., Cedillo-Rivera, R. 1999. Antiprotozoal Properties of Helianthemum glomeratum. Phytotherapy Research, 13(2): 102-105.
Quinone-Reductase-Inducer 3 uM
TNF-alpha-Inhibitor IC50=3.99 uM
Teratologic
Topoisomerase-I-Inhibitor Santti, R., Makela, S., Strauss, L., Korman, J., Kostian, M. L. 1998. Phytoestrogens: Potential Endocrine Disruptors in Males. Toxicol Ind Health, 14: 223-237.
Topoisomerase-II-Inhibitor IC50=8.1 ug/mlConstantinou, A., Mehta, R., Runyan, C., Rao, K., Vaughan, A., Moon, R. 1995. Flavonoids as DNA Topoisomerase Antagonists and Poisons: Structure-Activity Relationships. J Natural Products, 58: 217-225.
Tyrosinase-Inhibitor ID50=230 uM
Uterotrophic EC50=0.1-25 uM/lJournal of Medicinal Food 2: 227.1999.
Vasodilator
cAMP-Phosphodiesterase-Inhibitor
iNOS-Inhibitor IC50=<15 uM
iNOS-Inhibitor IC50=13.9 uM
KAEMPFEROL-GLUCOSIDE Leaf-- -- Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
LINOLEIC-ACID Root-- -- *
Activities (27)
5-Alpha-Reductase-Inhibitor
AntiMS Economic & Medicinal Plant Research, 6: 189.
Antiacne
Antialopecic
Antianaphylactic Economic & Medicinal Plant Research, 6: 189.
Antiandrogenic
Antiarteriosclerotic
Antiarthritic Economic & Medicinal Plant Research, 6: 189.
Anticoronary Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antieczemic Economic & Medicinal Plant Research, 6: 189.
Antifibrinolytic Economic & Medicinal Plant Research, 1: 53.
Antigranular
Antihistaminic Economic & Medicinal Plant Research, 6: 189.
Antiinflammatory IC50=31 uM
Antileukotriene-D4 IC50=31 uM
Antimenorrhagic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiprostatitic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Carcinogenic Science News, 146: 421.
Comedolytic
Hepatoprotective
Hypocholesterolemic Spiller, G. A. 1996 (Spiller, G. A. Ed. 1996. CRC Handbook of Lipids in Human Nutrition. CRC Press. Boca Raton, FL. 233 pp.)
Immunomodulator Economic & Medicinal Plant Research, 6: 189.
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Metastatic Science News, 146: 421.
Nematicide Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Propecic
LINOLENIC-ACID Root-- -- Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
LUTEOLIN Leaf-- -- Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Activities (78)
Aldose-Reductase-Inhibitor EC=3 ppmShin*, K.H., Chung, M.S., Chae, Y.J., Yoon, K.Y., Cho, T.S. 1992. A survey for aldose reductase inhibition of herbal medicines. Fitoterapia 64(2): 130, 1993.
Aldose-Reductase-Inhibitor IC50=0.45 uM rat
AntiHIV
Antiallergic
Antiangiogenic IC60-75=10 uM
Antiatherogenic
Antibacterial MIC=500 ug/mlPlanta Medica, 57: A43, 1991.
Anticarcinogenic
Anticarcinomic Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Anticataract EC=3 ppmShin*, K.H., Chung, M.S., Chae, Y.J., Yoon, K.Y., Cho, T.S. 1992. A survey for aldose reductase inhibition of herbal medicines. Fitoterapia 64(2): 130, 1993.
Anticomplementary
Antidermatic Bisset, N.G., ed. 1994. Herbal Drugs and Phytopharmaceuticals. CRC Press. Boca Raton, FL. 566 pp.
Antiestrogenic
Antifeedant IC52=<1,000 ppm dietLydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Antiherpetic 11-23 ug/ml
Antihistaminic <10-15 uM
Antiinflammatory #NAME?Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
Antileukemic 20-50 uM
Antilymphomic Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antimelanomic Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antimutagenic ID50=2-5 nM
Antimutagenic ID50=0.44 ug/ml
Antinociceptive
Antioxidant IC50=10 uM
Antipolio Economic & Medicinal Plant Research, 5: 197.
Antiproliferant
Antispasmodic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Antitumor 1-50 uM
Antitumor (Colon) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor (Kidney) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor (Lung) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor (Ovary) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor (Pancreas) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor (Skin) 20 uM
Antitumor (Stomach) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor (Thyroid) 12-50 uM
Antitumor (brain) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitussive
Antiviral 11-23 ug/ml
Aphidifuge
Apoptotic 12-50 uM
Aromatase-Inhibitor IC35=1 uM/lJournal of Medicinal Food 2: 235.1999.
Beta-Glucuronidase-Inhibitor IC50=~40 uM
Calcium-Antagonist IC50=1.2 uM rbt
Cancer-Preventive
Chemopreventive
Choleretic
Cytotoxic 1-50 uM
Deiodinase-Inhibitor Jim Duke's personal files.
Differentiator IC>40=40 uM
Diuretic Jim Duke's personal files.
Estrogenic 58% genistein
Hepatoprotective
Hyaluronidase-Inhibitor IC50+=100-250 uM
Hypocholesterolemic
ICAM-1-Inhibitor
IKK-Inhibitor
Iodothyronine-Deiodinase-Inhibitor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Lipoxygenase-Inhibitor
MAPK-Inhibitor
MMP-9-Inhibitor 20 uM
Metalloproteinase-Inhibitor
Myorelaxant
NEP-Inhibitor IC50=>42 uM
NF-kB-Inhibitor
NO-Inhibitor
PTK-Inhibitor 10-100 uM
Pesticide
Proliferant
Prostaglandin-Synthetase-Inhibitor
Protein-Kinase-C-Inhibitor IC70=50 uM
Succinoxidase-Inhibitor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
TNF-alpha-Inhibitor IC50=14.44 uM
Topoisomerase-I-Inhibitor Santti, R., Makela, S., Strauss, L., Korman, J., Kostian, M. L. 1998. Phytoestrogens: Potential Endocrine Disruptors in Males. Toxicol Ind Health, 14: 223-237.
VEGF-Inhibitor IC50=2-7 uM
Vasodilator
Xanthine-Oxidase-Inhibitor IC50=0.11 ug/mlChem. & Pharm. Bull. 38: 1772.
iNOS-Inhibitor
LUTEOLIN-7-GLUCOSIDE Leaf-- -- Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Activities (7)
Aldose-Reductase-Inhibitor IC73=10 uM
Aldose-Reductase-Inhibitor IC31=1 uMShimizu, M., Ito, T., Terashima, S., Hayashi, T., Arisawa, M., Morita, N., Kurokawa, S., Ito, K., and Hashimoto, Y. 1984. Inhibition of Lens Aldose Reductase by Flavonoids. Phytochemistry, 23: 1885-1888.
Antidermatic Bisset, N.G., ed. 1994. Herbal Drugs and Phytopharmaceuticals. CRC Press. Boca Raton, FL. 566 pp.
Antiherpetic Economic & Medicinal Plant Research, 5: 204.
Antiinflammatory Bisset, N.G., ed. 1994. Herbal Drugs and Phytopharmaceuticals. CRC Press. Boca Raton, FL. 566 pp.
Antiviral Economic & Medicinal Plant Research, 5: 204.
Pesticide
MYRISTIC-ACID Root-- -- *
Activities (6)
Antioxidant IC71=60
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Cosmetic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Hypercholesterolemic Spiller, G. A. 1996 (Spiller, G. A. Ed. 1996. CRC Handbook of Lipids in Human Nutrition. CRC Press. Boca Raton, FL. 233 pp.)
Lubricant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Nematicide Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
N-TRIACONTANOL Root-- -- Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
OLEIC-ACID Root-- -- *
Activities (18)
5-Alpha-Reductase-Inhibitor
Allergenic
Alpha-Reductase-Inhibitor
Anemiagenic
Antialopecic
Antiandrogenic
Antiinflammatory IC50=21 uM
Antileukotriene-D4 IC50=21 uM
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Choleretic 5 ml/man
Dermatitigenic
FLavor FEMA 1-30Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Hypocholesterolemic Spiller, G. A. 1996 (Spiller, G. A. Ed. 1996. CRC Handbook of Lipids in Human Nutrition. CRC Press. Boca Raton, FL. 233 pp.)
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Irritant Merck 11th Edition
Percutaneostimulant Seki, T., Toeda, C., Kawaguchi, T., Juni, K., Sugibayashi, K., and Morimoto, Y. 1990. Enhanced Transdermal Delivery of Zidovudine in Rats and Human Skin. Chem. Pharm. Bull. 38(11): 3086-3089, 1990.
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Propecic
PALMITIC-ACID Root-- -- *
Activities (13)
5-Alpha-Reductase-Inhibitor
Antialopecic
Antiandrogenic
Antifibrinolytic Economic & Medicinal Plant Research, 1: 53.
Antioxidant IC40=60
FLavor FEMA 1Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Hemolytic Bisset, N.G., ed. 1994. Herbal Drugs and Phytopharmaceuticals. CRC Press. Boca Raton, FL. 566 pp.
Hypercholesterolemic Spiller, G. A. 1996 (Spiller, G. A. Ed. 1996. CRC Handbook of Lipids in Human Nutrition. CRC Press. Boca Raton, FL. 233 pp.)
Lubricant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Nematicide Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Pesticide
Propecic
Soap Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
PENTA-(1,8Z)-DIENE Root-- -- Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
PENTADEC-1-ENE Root-- -- Jim Duke's personal files.
PENTADEC-1-ENE Root Essent. Oil-- -- Jim Duke's personal files.
PENTADEC-8-EN-2-ONE Root3600.0 4000.0 Jim Duke's personal files.
PENTADECA-1-CIS-8-DIENE Root Essent. Oil-- -- Jim Duke's personal files.
PENTADECA-2-TRANS-9-CIS-DIENE-12,14-DIYNOIC-ACID-ISOBUTYLAMIDE Root-- -- Jim Duke's personal files.
PENTADECA-8-EN-2-ONE Shoot-- -- Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
PENTADECA-TRANS-2-CIS-9-DIENE-12,14-DIYNOIC-ACID-ISOBUTYLAMIDE Root-- 13.7 Jim Duke's personal files.
PENTADECA-TRANS-9-CIS-13-DIEN-11-YN Root-- -- Jim Duke's personal files.
QUERCETAGETIN-7-GLUCOSIDE Leaf-- -- Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
QUERCETIN Leaf-- -- Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Activities (176)
11B-HSD-Inhibitor
5-Lipoxygenase-Inhibitor IC50 (uM)=4
ATPase-Inhibitor Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Aldehyde-Oxidase-Inhibitor IC70-96=10 uM
Aldose-Reductase-Inhibitor 100 uM
Aldose-Reductase-Inhibitor 4 ug/mlIchikawa, K., et al. 1991. Isolation and Structure Determination of Aldose Reductase Inhibitors from Traditional Thai Medicine, and Syntheses of Their Derivatives. Sankyo Kenkyusho Nempo, 43: 99-110.
Aldose-Reductase-Inhibitor IC50=0.84 ug/ml cowOkada,Y,et al.1995.Search for Naturally Occurring Substances to Prevent the Complications of Diabetes.II.Inhibitory Effect of Coumarin and Flavonoid Derivatives on Bovine Lens Aldose Reductase and Rabbit Platelet Aggregation.Chem Pharm Bull43(8):1385-1387
Aldose-Reductase-Inhibitor IC50=0.344 uMMao, X. M., Zhang, J. Q. 1993. Inhibition of Aldose Reductase by Extracts of Chinese Herbal Medicine. Zhongguo Zhongyao Zazhi , 18(10): 623-624.
Allelochemic IC82=1 mMLydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Allergenic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Analgesic
AntiCrohn's 400 mg/man/3x/dayPizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
AntiGTF ID50=120 ug/ml
AntiHIV
AntiPMS 500 mg/2x/day/wmnPizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiaflatoxin IC50=25 uM
Antiaflatoxin IC50=7.5 ppm
Antiaggregant IC50=55 uMEconomic & Medicinal Plant Research, 5: 333.
Antiaggregant 30 uM
Antiaging
Antiallergic IC50=14 uMJim Duke's personal files.
Antialzheimeran
Antianaphylactic Meli, R., Autore, G., Di Carlo, G., Capasso, F. Inhibitory Action of Quercetin on Intestinal Transit in Mice. Phytotherapy Research 4(5): 201, 1990.
Antiangiogenic
Antiarthritic
Antiasthmatic IC50=14 uM
Antiatherosclerotic
Antibacterial Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Anticarcinomic (Breast) IC50=1.5 uMMedline (post 1990 searches filed in my computer)
Anticariogenic ID50=120 ug/ml
Anticataract
Anticolitic 400 mg/man/3x/dayPizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Anticomplementary
Anticystitic 1,000 mg/day/4 weeks
Antidepressant
Antidermatitic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antidiabetic
Antielastase IC50=0.8 ug/ml
Antiencephalitic Economic & Medicinal Plant Research, 5: 199.
Antiescherichic
Antiestrogenic
Antifeedant IC52=<1,000 ppm dietLydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Antifibrosarcomic
Antiflu Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
Antigastric Rastitel'nye Resursy, 21: 85.
Antigonadotropic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antihepatotoxic Joyeux, M., Rolland, A., Fleurentin, J., Mortier, F., and Dorfman, P. 1989. Tert-Butyl Hydroperoxide-Induced Injury in Isolated Rat Hepatocytes: A Model for Studying Anti-Hepatotoxic Crude Drugs. Planta Medica 56(2): 171-173, 1990.
Antiherpetic 48-150 ug/ml
Antihistaminic IC50=<10 uM
Antihydrophobic Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
Antihypertensive Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Antiinflammatory 20-150 mg/kgFitoterapia No.5-1990.
Antileishmanic IC50=64
Antileukemic IC50=10 uMEconomic & Medicinal Plant Research, 5: 225.
Antileukemic IC50=>10 ug/mlLife Sciences 55: 1061.
Antileukemic 5.5-60 uM
Antileukotriene Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antilipoperoxidant IC67=50
Antimalarial IC50=1-6.4 ug/mlMedicinal and Poisonous Plants of the Tropics. Leeuwenberg, A.J.M., ed. Pudoc, Wageningen. 1987.
Antimelanomic
Antimetastatic
Antimutagenic ID50=2-5 nMPhenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
Antimutagenic ID50=0.62 ug/ml
Antimyocarditic Economic & Medicinal Plant Research, 5: 199.
Antinitrosaminic
Antinociceptive
Antioxidant IC96=300 ppmPhenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
Antioxidant ED50=2.3 uMSeidel, V., Verholle, M., Malard, Y., Tillequin, F., Fruchart, J-C., Duriez, P., Bailleul, F., Teissier, E. 2000. Phenylpropanoids from Ballota nigra L. Inhibit in vitro LDL Peroxidation. Phytotherapy Research, 14(2): 93-98.
Antioxidant 4.7 x Vit. E
Antioxidant IC47=10 uM
Antipancreatitic Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Antiperiodontal Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiperistaltic
Antipermeability
Antiperoxidant Planta Medica, 57: A110, 1991.
Antipharyngitic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiplaque Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiplasmodial IC50=13-64
Antipodriac
Antipolio Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiproliferant 10 nM
Antiprostanoid
Antiprostatitic Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Antipsoriac Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiradicular IC50=4.6 uMPlanta Medica, 56(6): 695, 1990.
Antispasmodic
Antistreptococcic ID50=120 ug/ml
Antithiamin Phenolic Compounds in Food and Their Effects on Health, 69.
Antithrombic
Antitrypanosomic IC50=13
Antitumor 10 uM
Antitumor (Bladder)
Antitumor (Breast)
Antitumor (Colon)
Antitumor (Lung)
Antitumor (Ovary)
Antitumor (Skin) 20 uM
Antitumor-Promoter Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiulcer
Antiviral IC50=10 uMEconomic & Medicinal Plant Research, 5: 225.
Antiviral 48-150 ug/mlAmoros, M., Simoes, C.M.O., Girre, L., et al. Synergistic Effect Of Flavones And Flavonols Against Herpes Simplex Virus Type 1 In Cell Culture. Comparison With The Antiviral Activity Of Propolis. J. of Natural Products 55(12):1732-1740, 1992.
Apoptotic 20-60 uM
Bacteristat 10 mg/ml
Bradycardiac Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
COMT-Inhibitor
COX-2-Inhibitor <40 uM
Calmodulin-Antagonist Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidicide
Capillariprotective Merck 11th Edition
Carcinogenic 40,000 ppm (diet) musNigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Catabolic
Copper-Chelator
Cyclooxygenase-Inhibitor
Cytochrome-P450-1A2-Inhibitor
Cytotoxic ED50=70 ug/mlMatsukawa, Y., et al. The Effect of Quercetin and Other Flavonoids on Cell Cycle Progresssion and Growth of Human Gastric Cancer Cells. Planta Medica, 56(6): 677, 1990.
Cytotoxic IC82=100 ug/mlPlanta Medica, 57: A113, 1991.
Deiodinase-Inhibitor Jim Duke's personal files.
Diaphoretic? Lawrence Review of Natural Products, Dec-90.
Differentiator 5.5 uM
Estrogenic 10% genistein
Fungicide
Glucosyl-Transferase-Inhibitor ID50=120 ug/ml
HIV-RT-Inhibitor IC50=<1 ug/mlNakane, H., Fukushima, M., and Ono*, K. Differential Inhibition Of Reverse Transcriptase And Various DNA Polymerases By Digallic Acid And Its Derivatives. Journal of Natural Products, 53(5): 1234-1240, 1990.
Hemostat Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Hepatomagenic 5,000 ppm (diet) ratPhenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
Hepatoprotective
Hypoglycemic 100 mg/kg orl ratIvorra, M.D., Paya, M., and Villar, A. 1989. A Review of Natural Products and Plants as Potential Antidiabetic Drugs. Journal of Ethnopharmacology, 27: 243-275, 1989.
Inotropic
Insulinogenic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Juvabional Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Larvistat 8,000 ppm dietLydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Lipoxygenase-Inhibitor IC11=1.25 mMOszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690.
Lipoxygenase-Inhibitor IC50=0.1-5 uM
MAO-A-Inhibitor
MMP-9-Inhibitor 20 uM
Mast-Cell-Stabilizer
Metal-Chelator (Copper) Seidel, V., Verholle, M., Malard, Y., Tillequin, F., Fruchart, J-C., Duriez, P., Bailleul, F., Teissier, E. 2000. Phenylpropanoids from Ballota nigra L. Inhibit in vitro LDL Peroxidation. Phytotherapy Research, 14(2): 93-98.
Metalloproteinase-Inhibitor IC50=>42 uM
Mutagenic
NADH-Oxidase-Inhibitor
NEP-Inhibitor IC50=>42 uM
NF-kB-Inhibitor
NO-Inhibitor IC>50=125 uM
NO-Inhibitor IC50=20 uM
NO-Synthase-Inhibitor 5-50 uM
Neuroprotective 5-25 uM
Ornithine-Decarboxylase-Inhibitor <10 uM
P450-Inducer 5 uMFather Nature's Farmacy: The aggregate of all these three-letter citations.
P450-Inhibitor 50-100 uMFather Nature's Farmacy: The aggregate of all these three-letter citations.
PGE2-Inhibitor
PTK-Inhibitor 0.4-24 uM
Pesticide
Phospholipase-Inhibitor
Plasmodicide Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
Proliferant
Prostaglandin-Synthesis-Inhibitor 40 ug/mlIbewuike, J. C., Ogungbamila, F. O., Ogundaini, A. O., Okeke, I. N., Bohlin, L. 1997. Antiinflammatory and Antibacterial Activities of C-methylflavonol from Piliostigma thonningii. Phytotherapy Research, 11(4): 281-284.
Protein-Kinase-C-Inhibitor Naim, M., Zehavi, U., Nagy, S., and Rouseff, R.L. Hydroxycinnamic Acids as Off-Flavor Precursors in Citrus Fruits and Their Products. Phenolic Compounds in Food and Their Effects on Health, Ch.14.
Quinone-Reductase-Inducer 6 uMUda, Y., Price, K. R., Williamson, G., Rhodes, M. J. C. 1997. Induction of the Anticarcinogenic Marker Enzyme, Quinone Reductase, in Murine Hepatoma Cells In Vitro by Flavonoids. Cancer Lett., 120 (2): 213-216.
Quinone-Reductase-Inducer 13 uM
TNF-alpha-Inhibitor IC50=3.11 uM
Teratologic
Topoisomerase-I-Inhibitor IC50=12.8 ug/ml
Topoisomerase-I-Inhibitor IC50=42 uM
Topoisomerase-II-Inhibitor IC50=1-6.9 ug/ml
Topoisomerase-II-Inhibitor IC50=23-40 uM
Tumorigenic 0.1% diet orl rat/yrJim Duke's personal files.
Tyrosinase-Inhibitor ID50=70 uM
Tyrosine-Kinase-Inhibitor Economic & Medicinal Plant Research, 6: 170.
VEGF-Inhibitor
Vasodilator
Xanthine-Oxidase-Inhibitor IC50=>0.4 ug/mlChem. & Pharm. Bull. 38: 1772.
Xanthine-Oxidase-Inhibitor IC50=10.6 ug/ml
Xanthine-Oxidase-Inhibitor 3.1 uM
cAMP-Phosphodiesterase-Inhibitor Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
iNOS-Inhibitor IC50=20 uM
RUTOSIDE Leaf-- -- Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Activities (4)
Antiaggregant
Anticapillary-Fragility
COMT-Inhibitor
Choleretic 50 mg/kg ipr
SITOSTEROL-3-O-BETA-D-GLUCOSIDE Leaf-- -- Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
STIGMASTEROL Root-- -- Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Activities (12)
Antihepatotoxic
Antiinflammatory Lawrence Review of Natural Products, 1995
Antinociceptive
Antiophidic 2.3 mg ipr musEconomic & Medicinal Plant Research, 5: 363.
Antioxidant IC33=10 uM
Antiviral Abid Ali Khan, M.M., Jain, D.C., Bhakuni, R.S., Zaim, M., and Thakur, R.S. 1991. Occurrence of some antiviral sterols in Artemisia annua. Plant Science, 75: 161-165, 1991.
Artemicide LC50=110 ppmJung, J.H., Pummangura, S., Chaichantipyuth, c., Patarapanich, C., and McLaughlin, J.L. 1989. Bioactive Constituents of Melodorum fruticosum. Phytochemistry. 29(5): 1667-1670. 1990.
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Estrogenic
Hypocholesterolemic Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Ovulant
Sedative
SUCROSE Root-- 69200.0 -0.56 Jim Duke's personal files.
Activities (14)
Aggregant Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antihiccup 1 tspMartindale's 29th
Antiophthalmic Martindale's 29th
Antioxidant Merck 11th Edition
Atherogenic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Collyrium Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Demulcent Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Flatugenic Singh, J., Gupta, K., and Arora, S.K. 1993. Changes in the anti-nutritional factors of developing seeds and pod walls of fenugreek (Trigonella foenum graecum L.). Plant Foods for Human Nutrition. 46: 77-84, 1994.
Hypercholesterolemic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Preservative Merck 11th Edition
Sweetener 1 x sucroseMerck 11th Edition
Triglycerigenic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Uricogenic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Vulnerary Martindale's 29th
TRIDEC-1-ENE-3-5-7-9-11-PENTAYNE Stem-- 500.0 1.0 Jim Duke's personal files.
TRIDEC-1-ENE-3-5-7-9-11-PENTAYNE Flower-- 800.0 -1.0 Jim Duke's personal files.
TRIDEC-1-ENE-3-5-7-9-11-PENTAYNE Root3.0 9000.0 0.64 Jim Duke's personal files.
TRIDECA-1,3-DIENE-5,7,9,11-TETRAYNE Root-- 100.0 Jim Duke's personal files.
TRIDECA-1-11-DIENE-3-5-7-9-TETRAYNE Root-- 100.0 -0.55 Jim Duke's personal files.
TRIDECA-2-TRANS-7-CIS-DIENE-10,12-DIYNOIC-ACID-ISOBUTYLAMINE Root-- -- Jim Duke's personal files.
TRIDECA-8,10,12-TRIENE-2,4,6-TRIYNE Flower-- -- Jim Duke's personal files.
TRIDECA-8,10,12-TRIENE-2,4,6-TRIYNE Root100.0 200.0 -1.0 Jim Duke's personal files.
TRIDECA-TRANS-2-CIS-7-DIENE-10,12-DIYNOIC-ACID-ISOBUTYLAMIDE Root-- 6.8 1.0 Jim Duke's personal files.
TUSSILAGIN Plant-- -- Jim Duke's personal files.
TUSSILAGINE Root15.0 60.0 Bisset, N.G., ed. 1994. Herbal Drugs and Phytopharmaceuticals. CRC Press. Boca Raton, FL. 566 pp.
Activities (1)
Calcium-Antagonist IC50=1.2 uM
UNDECA-2-CIS-4-TRANS-DIENE-8,10-DIYNOIC-ACID-ISOBUTYLAMIDE Root-- -- Jim Duke's personal files.
UNDECA-2-CIS-ENE-8,10-DIYNOIC-ACID-2-METHYL-BUTYLAMIDE Root-- -- Jim Duke's personal files.
UNDECA-2-CIS-ENE-8,10-DIYNOIC-ACID-ISOBUTYLAMIDE Root-- -- Jim Duke's personal files.
UNDECA-2-TRANS-4-CIS-8,10-DIYNOIC-ACID-ISOBUTYLAMIDE Root-- -- Jim Duke's personal files.
UNDECA-2-TRANS-4-CIS-DIENE-8,10-DIYNOIC-ACID-ISOBUTYLAMIDE Shoot-- -- Jim Duke's personal files.
UNDECA-2-TRANS-ENE-8,10-DIYNOIC-ACID-ISOBUTYLAMIDE Root-- -- Jim Duke's personal files.
UNDECA-CIS-2,8,10-DIYNOIC-ACID-ISOBUTYLAMIDE Root-- 31.0 Jim Duke's personal files.
UNDECA-CIS-2-ENE-8,10-DIYNOIC-ACID-2-METHYL-BUTYLAMIDE Root-- 6.8 Jim Duke's personal files.
UNDECA-CIS-2-ENE-8,10-DIYNOIC-ACID-ISOBUTYLAMIDE Root-- 103.4 Jim Duke's personal files.
UNDECA-CIS-2-TRANS-4-DIENE-2,4-DIYN-1-OIC-ACID-ISOBUTYLAMIDE Root-- 298.5 1.0 Jim Duke's personal files.
UNDECA-CIS-2-TRANS-4-DIENE-8,10-DIYNOIC-ACID-ISOBUTYLAMIDE Root-- 13.7 1.0 Jim Duke's personal files.
UNDECA-TRANS-2-CIS-4-DIENE-8,10-DIYNOIC-ACID-ISOBUTYLAMIDE Root-- 10.3 1.0 Jim Duke's personal files.
*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.