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Activities: 257
All Chemicals: 46
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Chemical Low PPM High PPM StdDev *Reference
1-(1',2'-DIHYDROXYETHYL)-4-METHOXY-BETA-CARBOLINE Root Bark-- -- *
1-(2'-HYDROXYETHYL)-4-METHOXY-BETA-CARBOLINE Root Bark-- -- *
1-ACETYL-4-METHOXY-BETA-CARBOLINE Root Bark-- -- *
1-HYDROXYCANTHIN-6-ONE Tissue Culture-- -- *
1-METHOXYCANTHIN-6-ONE Wood-- -- *
Activities (3)
Antibacterial
Antitumor
Pesticide
1-METHOXYCANTHIN-6-ONE-3N-OXIDE Root Bark-- -- *
2,6-DIMETHOXY-P-BENZOQUINONE Bark-- -- *
Activities (3)
Antibacterial
Fungicide Recio, M. C., Rios, J. L., and Villar, A., A review of some antimicrobial compounds isolated from medicinal plants reported in the literature 1978-1988, Phytotherapy Research, 3(4), 1989, 117-125.
Pesticide
2,6-DIMETHOXYQUINONE Plant-- -- *
ACETYLAMAROLIDE Bark-- -- *
AILANTHIIN Plant-- 49600.0 *
AILANTHINONE Bark-- -- *
Activities (8)
Amebicide IC50=0.132 uM
Antigiardial IC50=45 uM
Antileukemic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antimalarial IC50=0.025 uM
Antiplasmodial IC50=0.019 uM
Antitrypanosomic IC50=0.025 uM
Pesticide
Protisticide IC50=0.019-45 uM
AILANTHONE Fruit-- -- *
Activities (8)
Amebicide Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antibacterial IC17=12.5 ug/ml
Antifeedant
Antimalarial Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Antiplasmodial
Antitubercular IC17=12.5 ug/ml
Mycobactericide IC17=12.5 ug/ml
Pesticide
AMAROLIDE Bark-- -- *
BETA-SITOSTEROL Plant-- -- *
Activities (47)
Androgenic
Angiogenic
Anorexic Martindale's 28th
Antiadenomic Merck 11th Edition
Antiandrogenic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antibacterial Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155.
Anticancer (Breast) Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103.
Anticancer (Cervix)
Anticancer (Lung)
Antiedemic IC54=320 mg/kg orl
Antiestrogenic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antifeedant Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Antifertility Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antigonadotrophic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antihyperlipoproteinaemic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiinflammatory
Antileukemic
Antilymphomic
Antimutagenic 250 ug/ml
Antiophidic 2.3 mg musEconomic & Medicinal Plant Research, 5: 363.
Antioxidant IC44=10 uM
Antiprogestational Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antiprostaglandin 30 mg/day/12 wks
Antiprostatadenomic Merck 11th Edition
Antiprostatitic 10-20 mg 3 x/day/orl man
Antipyretic Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
Antitumor (Breast) Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103.
Antitumor (Cervix)
Antitumor (Lung)
Antiviral Abid Ali Khan, M.M., Jain, D.C., Bhakuni, R.S., Zaim, M., and Thakur, R.S. 1991. Occurrence of some antiviral sterols in Artemisia annua. Plant Science, 75: 161-165, 1991.
Apoptotic
Artemicide LC50=110 ppmJung, J.H., Pummangura, S., Chaichantipyuth, c., Patarapanich, C., and McLaughlin, J.L. 1989. Bioactive Constituents of Melodorum fruticosum. Phytochemistry. 29(5): 1667-1670. 1990.
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidicide Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155.
Caspase-8-Inducer
Estrogenic
Febrifuge Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
Gonadotrophic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Hepatoprotective
Hypocholesterolemic 2-6 g/man/day/orlMartindale's 30th
Hypocholesterolemic 9-3,330 mg/man/day/orlMartindale's 28th
Hypoglycemic Ivorra, M.D., Paya, M., and Villar, A. 1989. A Review of Natural Products and Plants as Potential Antidiabetic Drugs. Journal of Ethnopharmacology, 27: 243-275, 1989.
Hypolipidemic 2-6 g/day
Pesticide
Spermicide Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Ubiquiot Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Ulcerogenic 500 mg/kg ipr rat
CALCIUM-OXALATE Plant-- -- *
Activities (4)
Emetic
Inflammatory
Laxative
Lithogenic
CANTHIN-6-ONE Wood-- -- *
Activities (8)
Antibacterial MIC=12.5-75 ug/mlCollins, D.J., Culvenor, C.C.J., Lamberton, J.A., Loder, J.W. and Price, J.R., Plants for Medicines, CSIRO, East Melbourne, Australia, 1990, 303 pp.
Antileukemic
Antimycotic
Antiseptic Bettarini, F., Borgonovi, G.E., et al. 1991. Antiparasitic Compounds from East African Plants: Isolation and Biological Activity of Anonaine, Matricarianol, Canthin-6-One and Caryophyllene Oxide. Insect Sci. Applic. 14(1): 93-99, 1993.
Cytotoxic IC50=1-6 ug/mlCollins, D.J., Culvenor, C.C.J., Lamberton, J.A., Loder, J.W. and Price, J.R., Plants for Medicines, CSIRO, East Melbourne, Australia, 1990, 303 pp.
Fungicide
Pesticide
cAMP-Inhibitor Collins, D.J., Culvenor, C.C.J., Lamberton, J.A., Loder, J.W. and Price, J.R., Plants for Medicines, CSIRO, East Melbourne, Australia, 1990, 303 pp.
CANTHIN-6-ONE-3-OXIDE Wood-- -- *
CARBOLINE-1-CARBOXYLATE Bark-- -- *
CELLULOSE Bark-- -- *
Activities (1)
Hemostat Martindale's 29th
CERYL-ALCOHOL Plant-- -- *
CERYL-PALMITATE Bark-- -- *
ELAIDIC-ACID Plant-- -- *
Activities (2)
Antiinflammatory IC50=54 uM
Antileukotriene-D4 IC50=54 uM
FAT Seed555000.0 591000.0 1.72 *
FISETIN Plant-- -- *
Activities (15)
5-Lipoxygenase-Inhibitor IC50 (uM)=11
ACE-Inhibitor IC50=150 uM/
Allergenic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antihistaminic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antimutagenic ID50=10-40 nMPhenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
Antioxidant Jim Duke's personal files.
Antiviral Economic & Medicinal Plant Research, 5: 197.
Cyclooxygenase-Inhibitor IC50 (uM) =80
Iodothyronine-Deiodinase-Inhibitor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Lipoxygenase-Inhibitor IC50 (uM)=11
Lipoxygenase-Inhibitor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Oxidase-Inhibitor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
Topoisomerase-I-Inhibitor IC50=20.6 ug/ml
Topoisomerase-II-Inhibitor IC50=8.2 ug/mlConstantinou, A., Mehta, R., Runyan, C., Rao, K., Vaughan, A., Moon, R. 1995. Flavonoids as DNA Topoisomerase Antagonists and Poisons: Structure-Activity Relationships. J Natural Products, 58: 217-225.
GALLIC-ACID Plant-- -- *
Activities (62)
ACE-Inhibitor IC50=7.7 mM/l
Analgesic
AntiHIV
AntiMRSA
Antiadenovirus Economic & Medicinal Plant Research, 5: 194.
Antiallergenic Dorsch, W., Wagner, H. New Antiasthmatic Drugs from Traditional Medicine? Int Arch Allergy Appl Immunol 94: 262-265, 1991.
Antianaphylactic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiangiogenic
Antiasthmatic Watt, J.M., and Breyer-Brandwijk, M.G. The Medicinal and Poisonous Plants of Southern and Eastern Africa. 1962.
Antibacterial MIC=1,000 ug/ml
Antibronchitic Dorsch, W., Wagner, H. New Antiasthmatic Drugs from Traditional Medicine? Int Arch Allergy Appl Immunol 94: 262-265, 1991.
Anticancer
Anticarcinomic ED50=3
Antiescherichic
Antifibrinolytic Economic & Medicinal Plant Research, 1: 53.
Antiflu Economic & Medicinal Plant Research, 5: 194.
Antihepatotoxic Okuda, T., Yoshida, T., and Hatano, T. Antioxidant Effects of Tannins and Related Polyphenols. Phenolic Compounds in Food and Their Effects on Health, Ch.7 p.93.
Antiherpetic EC50=>10 ug/ml
Antiinflammatory Kroes, B.H., et al. 1991. Anti-Inflammatory Activity of Gallic Acid. Planta Medica, 58(6): 499.
Antileishmanic EC50=4.4 ug/ml
Antimutagenic Economic & Medicinal Plant Research, 6: 235.
Antinitrosaminic
Antioxidant IC44=33 ppm
Antioxidant 7 x quercetin
Antioxidant 2/3 BHA
Antiperiodontitic 10 ug/ml
Antiperoxidant IC50=69 uM
Antipolio Economic & Medicinal Plant Research, 5: 194.
Antiproteolytic 10 ug/ml
Antiradicular 7 x quercetin
Antiradicular IC50=4.9 uM
Antiseptic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Antistaphylococcic MIC=1,000 ug/ml
Antitumor
Antitumor-Promoter
Antiviral
Apoptotic
Astringent Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Bacteristat Lamikanra, A., Ogundaini, A.O., and Ogungbamila*, F.O. Antibacterial Constituents of Alchornea cordifolia Leaves. Phytotherapy Research 4(5): 198.
Bronchodilator Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidicide
Carcinogenic
Choleretic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Cyclooxygenase-Inhibitor
Cytotoxic 500 uM
Floral-Inhibitor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Gram(+)icide MIC=1,000 ug/ml
Gram(-)icide MIC=1,000 ug/ml
Hemostat
Hepatoprotective Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
Immunomodulator
Immunostimulant McKenna, D. J., Hughes, K., and Jones, K. 2000. Green Tea Monograph. Alternative Therapies, 6(3): 61-82.
Immunosuppressant
Insulin-Sparing Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Myorelaxant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
NO-Inhibitor IC-26=250 uM
Nephrotoxic Martindale's 29th
Pesticide
Styptic
Topoisomerase-I-Inhibitor Hamada, S. I., Kataoka, T., Woo, J. T., Yamada, A., Yoshida, T., Nishimura, T., Otake, N., Nagai, K. 1997. Immunosuppressive Effects by Gallic Acid and Chebulagic Acid on CTL-Mediated Cytotoxicity. Biol Pharm Bull, 20: 1017-1019.
Xanthine-Oxidase-Inhibitor IC50=24 uMHatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
HEMICELLULOSE Plant-- -- *
HOLOCELLULOSE Plant-- -- *
ISOQUERCETIN Leaf-- -- *
Activities (3)
Antiretroviral
Antiviral
Pesticide
ISOQUERCITRIN Leaf-- -- *
Activities (22)
ACE-Inhibitor ID50=300 ug/ml rat (24 hr.)
Aldose-Reductase-Inhibitor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antibacterial Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Anticancer
Antielastase IC50=0.7 ug/ml
Antifeedant Russell, G. B., Phytochemical resources for crop protection, N. Z. J. Technol., 2, 1986, 127-134.
Antiinflammatory
Antinociceptive
Antioxidant 1/4 quercetin
Antioxidant IC50=9.0 uM
Antiradicular 1/4 quercetin
Antitumor
Antitumor-Promoter
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Capillarigenic
Diaphoretic
Diuretic 10 ppmList, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Hypotensive Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990.
Insectiphile Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
TNF-alpha-Inhibitor
Topoisomerase-II-Inhibitor 550 ug/mlBernard, F. X., Sable, S., Cameron, B., Provost, J., Desnottes, J. F., Crouzet, J., Blanche, F. 1997. Glycosylated Flavones as Selective Inhibitors of Topoisomerase IV. Antimicrobial Agents & Chemotherapy, 41: 992-998.
LIGNIN Plant-- -- *
Activities (13)
AntiHIV
Antibacterial
Anticancer
Anticoronary
Antidiarrheic Martindale's 29th
Antinitrosaminic
Antioxidant
Antitumor
Antiviral
Chelator
Hypocholesterolemic
Laxative
Pesticide
LINUTHIN Leaf-- -- *
METHYL-4-METHOXY-BETA-CARBOLINE-1-CARBOXYLATE Root Bark-- -- *
MUCILAGE Plant-- -- *
Activities (3)
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Demulcent
Hypocholesterolemic
NEOQUASSIN Plant-- -- *
OLEORESIN Plant-- -- *
PHLOBAPHENE Bark-- -- *
POLYSACCHARIDE Bark-- -- *
PROTEIN Seed275000.0 276000.0 0.38 *
QUASSIIN Bark-- 49600.0 *
QUASSIN Plant-- -- *
Activities (5)
Amebicide 100 ppm
Apertif
Emetic Oriental Materia Medica (three volumes by Dr. Hsu and collaborators)
Insecticide Grenand, P., Moretti, C., and Jacquemin, H. 1987. Pharmacopees Traditionnelles en Guyane. l'ORSTROM, Paris. 569 pp.
Pesticide
QUERCETIN Leaf-- -- *
Activities (176)
11B-HSD-Inhibitor
5-Lipoxygenase-Inhibitor IC50 (uM)=4
ATPase-Inhibitor Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Aldehyde-Oxidase-Inhibitor IC70-96=10 uM
Aldose-Reductase-Inhibitor 100 uM
Aldose-Reductase-Inhibitor 4 ug/mlIchikawa, K., et al. 1991. Isolation and Structure Determination of Aldose Reductase Inhibitors from Traditional Thai Medicine, and Syntheses of Their Derivatives. Sankyo Kenkyusho Nempo, 43: 99-110.
Aldose-Reductase-Inhibitor IC50=0.84 ug/ml cowOkada,Y,et al.1995.Search for Naturally Occurring Substances to Prevent the Complications of Diabetes.II.Inhibitory Effect of Coumarin and Flavonoid Derivatives on Bovine Lens Aldose Reductase and Rabbit Platelet Aggregation.Chem Pharm Bull43(8):1385-1387
Aldose-Reductase-Inhibitor IC50=0.344 uMMao, X. M., Zhang, J. Q. 1993. Inhibition of Aldose Reductase by Extracts of Chinese Herbal Medicine. Zhongguo Zhongyao Zazhi , 18(10): 623-624.
Allelochemic IC82=1 mMLydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Allergenic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Analgesic
AntiCrohn's 400 mg/man/3x/dayPizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
AntiGTF ID50=120 ug/ml
AntiHIV
AntiPMS 500 mg/2x/day/wmnPizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiaflatoxin IC50=25 uM
Antiaflatoxin IC50=7.5 ppm
Antiaggregant IC50=55 uMEconomic & Medicinal Plant Research, 5: 333.
Antiaggregant 30 uM
Antiaging
Antiallergic IC50=14 uMJim Duke's personal files.
Antialzheimeran
Antianaphylactic Meli, R., Autore, G., Di Carlo, G., Capasso, F. Inhibitory Action of Quercetin on Intestinal Transit in Mice. Phytotherapy Research 4(5): 201, 1990.
Antiangiogenic
Antiarthritic
Antiasthmatic IC50=14 uM
Antiatherosclerotic
Antibacterial Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Anticarcinomic (Breast) IC50=1.5 uMMedline (post 1990 searches filed in my computer)
Anticariogenic ID50=120 ug/ml
Anticataract
Anticolitic 400 mg/man/3x/dayPizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Anticomplementary
Anticystitic 1,000 mg/day/4 weeks
Antidepressant
Antidermatitic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antidiabetic
Antielastase IC50=0.8 ug/ml
Antiencephalitic Economic & Medicinal Plant Research, 5: 199.
Antiescherichic
Antiestrogenic
Antifeedant IC52=<1,000 ppm dietLydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Antifibrosarcomic
Antiflu Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
Antigastric Rastitel'nye Resursy, 21: 85.
Antigonadotropic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antihepatotoxic Joyeux, M., Rolland, A., Fleurentin, J., Mortier, F., and Dorfman, P. 1989. Tert-Butyl Hydroperoxide-Induced Injury in Isolated Rat Hepatocytes: A Model for Studying Anti-Hepatotoxic Crude Drugs. Planta Medica 56(2): 171-173, 1990.
Antiherpetic 48-150 ug/ml
Antihistaminic IC50=<10 uM
Antihydrophobic Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
Antihypertensive Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Antiinflammatory 20-150 mg/kgFitoterapia No.5-1990.
Antileishmanic IC50=64
Antileukemic IC50=10 uMEconomic & Medicinal Plant Research, 5: 225.
Antileukemic IC50=>10 ug/mlLife Sciences 55: 1061.
Antileukemic 5.5-60 uM
Antileukotriene Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antilipoperoxidant IC67=50
Antimalarial IC50=1-6.4 ug/mlMedicinal and Poisonous Plants of the Tropics. Leeuwenberg, A.J.M., ed. Pudoc, Wageningen. 1987.
Antimelanomic
Antimetastatic
Antimutagenic ID50=2-5 nMPhenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
Antimutagenic ID50=0.62 ug/ml
Antimyocarditic Economic & Medicinal Plant Research, 5: 199.
Antinitrosaminic
Antinociceptive
Antioxidant IC96=300 ppmPhenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
Antioxidant ED50=2.3 uMSeidel, V., Verholle, M., Malard, Y., Tillequin, F., Fruchart, J-C., Duriez, P., Bailleul, F., Teissier, E. 2000. Phenylpropanoids from Ballota nigra L. Inhibit in vitro LDL Peroxidation. Phytotherapy Research, 14(2): 93-98.
Antioxidant 4.7 x Vit. E
Antioxidant IC47=10 uM
Antipancreatitic Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Antiperiodontal Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiperistaltic
Antipermeability
Antiperoxidant Planta Medica, 57: A110, 1991.
Antipharyngitic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiplaque Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiplasmodial IC50=13-64
Antipodriac
Antipolio Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiproliferant 10 nM
Antiprostanoid
Antiprostatitic Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Antipsoriac Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiradicular IC50=4.6 uMPlanta Medica, 56(6): 695, 1990.
Antispasmodic
Antistreptococcic ID50=120 ug/ml
Antithiamin Phenolic Compounds in Food and Their Effects on Health, 69.
Antithrombic
Antitrypanosomic IC50=13
Antitumor 10 uM
Antitumor (Bladder)
Antitumor (Breast)
Antitumor (Colon)
Antitumor (Lung)
Antitumor (Ovary)
Antitumor (Skin) 20 uM
Antitumor-Promoter Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiulcer
Antiviral IC50=10 uMEconomic & Medicinal Plant Research, 5: 225.
Antiviral 48-150 ug/mlAmoros, M., Simoes, C.M.O., Girre, L., et al. Synergistic Effect Of Flavones And Flavonols Against Herpes Simplex Virus Type 1 In Cell Culture. Comparison With The Antiviral Activity Of Propolis. J. of Natural Products 55(12):1732-1740, 1992.
Apoptotic 20-60 uM
Bacteristat 10 mg/ml
Bradycardiac Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
COMT-Inhibitor
COX-2-Inhibitor <40 uM
Calmodulin-Antagonist Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidicide
Capillariprotective Merck 11th Edition
Carcinogenic 40,000 ppm (diet) musNigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Catabolic
Copper-Chelator
Cyclooxygenase-Inhibitor
Cytochrome-P450-1A2-Inhibitor
Cytotoxic ED50=70 ug/mlMatsukawa, Y., et al. The Effect of Quercetin and Other Flavonoids on Cell Cycle Progresssion and Growth of Human Gastric Cancer Cells. Planta Medica, 56(6): 677, 1990.
Cytotoxic IC82=100 ug/mlPlanta Medica, 57: A113, 1991.
Deiodinase-Inhibitor Jim Duke's personal files.
Diaphoretic? Lawrence Review of Natural Products, Dec-90.
Differentiator 5.5 uM
Estrogenic 10% genistein
Fungicide
Glucosyl-Transferase-Inhibitor ID50=120 ug/ml
HIV-RT-Inhibitor IC50=<1 ug/mlNakane, H., Fukushima, M., and Ono*, K. Differential Inhibition Of Reverse Transcriptase And Various DNA Polymerases By Digallic Acid And Its Derivatives. Journal of Natural Products, 53(5): 1234-1240, 1990.
Hemostat Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Hepatomagenic 5,000 ppm (diet) ratPhenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
Hepatoprotective
Hypoglycemic 100 mg/kg orl ratIvorra, M.D., Paya, M., and Villar, A. 1989. A Review of Natural Products and Plants as Potential Antidiabetic Drugs. Journal of Ethnopharmacology, 27: 243-275, 1989.
Inotropic
Insulinogenic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Juvabional Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Larvistat 8,000 ppm dietLydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Lipoxygenase-Inhibitor IC11=1.25 mMOszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690.
Lipoxygenase-Inhibitor IC50=0.1-5 uM
MAO-A-Inhibitor
MMP-9-Inhibitor 20 uM
Mast-Cell-Stabilizer
Metal-Chelator (Copper) Seidel, V., Verholle, M., Malard, Y., Tillequin, F., Fruchart, J-C., Duriez, P., Bailleul, F., Teissier, E. 2000. Phenylpropanoids from Ballota nigra L. Inhibit in vitro LDL Peroxidation. Phytotherapy Research, 14(2): 93-98.
Metalloproteinase-Inhibitor IC50=>42 uM
Mutagenic
NADH-Oxidase-Inhibitor
NEP-Inhibitor IC50=>42 uM
NF-kB-Inhibitor
NO-Inhibitor IC>50=125 uM
NO-Inhibitor IC50=20 uM
NO-Synthase-Inhibitor 5-50 uM
Neuroprotective 5-25 uM
Ornithine-Decarboxylase-Inhibitor <10 uM
P450-Inducer 5 uMFather Nature's Farmacy: The aggregate of all these three-letter citations.
P450-Inhibitor 50-100 uMFather Nature's Farmacy: The aggregate of all these three-letter citations.
PGE2-Inhibitor
PTK-Inhibitor 0.4-24 uM
Pesticide
Phospholipase-Inhibitor
Plasmodicide Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
Proliferant
Prostaglandin-Synthesis-Inhibitor 40 ug/mlIbewuike, J. C., Ogungbamila, F. O., Ogundaini, A. O., Okeke, I. N., Bohlin, L. 1997. Antiinflammatory and Antibacterial Activities of C-methylflavonol from Piliostigma thonningii. Phytotherapy Research, 11(4): 281-284.
Protein-Kinase-C-Inhibitor Naim, M., Zehavi, U., Nagy, S., and Rouseff, R.L. Hydroxycinnamic Acids as Off-Flavor Precursors in Citrus Fruits and Their Products. Phenolic Compounds in Food and Their Effects on Health, Ch.14.
Quinone-Reductase-Inducer 6 uMUda, Y., Price, K. R., Williamson, G., Rhodes, M. J. C. 1997. Induction of the Anticarcinogenic Marker Enzyme, Quinone Reductase, in Murine Hepatoma Cells In Vitro by Flavonoids. Cancer Lett., 120 (2): 213-216.
Quinone-Reductase-Inducer 13 uM
TNF-alpha-Inhibitor IC50=3.11 uM
Teratologic
Topoisomerase-I-Inhibitor IC50=12.8 ug/ml
Topoisomerase-I-Inhibitor IC50=42 uM
Topoisomerase-II-Inhibitor IC50=1-6.9 ug/ml
Topoisomerase-II-Inhibitor IC50=23-40 uM
Tumorigenic 0.1% diet orl rat/yrJim Duke's personal files.
Tyrosinase-Inhibitor ID50=70 uM
Tyrosine-Kinase-Inhibitor Economic & Medicinal Plant Research, 6: 170.
VEGF-Inhibitor
Vasodilator
Xanthine-Oxidase-Inhibitor IC50=>0.4 ug/mlChem. & Pharm. Bull. 38: 1772.
Xanthine-Oxidase-Inhibitor IC50=10.6 ug/ml
Xanthine-Oxidase-Inhibitor 3.1 uM
cAMP-Phosphodiesterase-Inhibitor Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
iNOS-Inhibitor IC50=20 uM
RHAMNOSE Plant-- -- *
SAPONIN Bark-- -- *
SCOPOLETIN Plant-- -- *
Activities (44)
Aldose-Reductase-Inhibitor IC50=6.2 ug/ml cowOkada,Y,et al.1995.Search for Naturally Occurring Substances to Prevent the Complications of Diabetes.II.Inhibitory Effect of Coumarin and Flavonoid Derivatives on Bovine Lens Aldose Reductase and Rabbit Platelet Aggregation.Chem Pharm Bull43(8):1385-1387
Allelochemic IC89=2 mMLydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Analgesic
Anesthetic Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
Antiadrenergic Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
Antiaflatoxin IC50=65 uM
Antiaflatoxin 11.4 ppm
Antiarrhythmic
Antiasthmatic
Antibacterial Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antibronchoconstrictor
Anticholinergic
Antiedemic
Antifeedant Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Antihepatotoxic Bisset, N.G., ed. 1994. Herbal Drugs and Phytopharmaceuticals. CRC Press. Boca Raton, FL. 566 pp.
Antiinflammatory ED 1-10 ug/ear
Antileukotrienogenic
Antimutagenic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
Antioxidant
Antiproliferant
Antiprostaglandin
Antiseptic
Antispasmodic
Antitumor 2.9 ug/ml
Apoptotic
Bronchorelaxant Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
CNS-Depressant Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
CNS-Stimulant Watt, J.M. and Breyer-Brandwijk, M.G. 1962. The Medicinal and Poisonous Plants of Southern and Eastern Africa. E. & S. Livingstone, Ltd. Edinburg & London. 1457 pp.
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Cholagogue Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
Choleretic Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Cytotoxic
Fungicide 2 mM
Hepatoprotective Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
Herbicide Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Hypoglycemic Economic & Medicinal Plant Research, 6: 165
Hypotensive
MAO-Inhibitor
Musculotropic Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
Myorelaxant
Pesticide
Phytoalexin
Phytohormonal Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Uterosedative Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
SHINJULACTONE-C Root Bark-- 10.0 *
TANNIN Leaf-- 120000.0 0.12 *
Activities (35)
Anthelmintic
AntiHIV
Antibacterial
Anticancer
Anticariogenic
Antidiarrheic
Antidysenteric
Antihepatotoxic
Antihypertensive
Antilipolytic
Antimutagenic
Antinephritic Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990.
Antiophidic Economic & Medicinal Plant Research, 5: 363.
Antioxidant IC50=1.44 ug/ml
Antioxidant 1/3 quercetin
Antiradicular 500 mg/kg/day orl musUchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990.
Antiradicular 1/3 quercetin
Antirenitic Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990.
Antitumor
Antitumor-Promoter
Antiulcer
Antiviral
Cancer-Preventive HerbalGram No. 22 - Spring 1990, page 14.
Carcinogenic
Chelator
Cyclooxygenase-Inhibitor
Glucosyl-Transferase-Inhibitor
Hepatoprotective
Immunosuppressant
Lipoxygenase-Inhibitor
MAO-Inhibitor
Ornithine-Decarboxylase-Inhibitor
Pesticide
Psychotropic Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990.
Xanthine-Oxidase-Inhibitor
*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.