Data Views Exclude Ubiquitous Chemicals

Activities: 273
All Chemicals: 101
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Chemical Low PPM High PPM StdDev *Reference
BETA-PINENE Tissue Culture-- -- Jim Duke's personal files.
Activities (13)
Allergenic
Antiinflammatory
Antiseptic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Antispasmodic
Candidicide
FLavor FEMA 15-600Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Herbicide Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
Spasmogenic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Transdermal
PARA-CYMENE Tissue Culture-- -- Jim Duke's personal files.
AGASTACHOSIDE Shoot-- -- Jim Duke's personal files.
BETA-HUMULENE Tissue Culture-- -- Jim Duke's personal files.
CARYOPHYLLENOL-II Shoot-- -- Jim Duke's personal files.
ESTRAGOLE Plant-- -- Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Activities (12)
Antiaggregant IC50=320 uMLaekeman, G.M., Van Hoof, L., Haemers, A., Vanden Berghe, D.A., Herman, A.G., and Vlietinck, A.J. Eugenol a Valuable Compound for In Vitro Experimental Research and Worthwhile for Further In Vivo Investigation. Phytotherapy Research 4(3): 93, 1990.
Calcium-Antagonist IC50=257.6 uM gpg
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Carcinogenic 4.4 uM/15 mos. scu mus
DNA-Binder Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
FLavor FEMA 4-150Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Hepatocarcinogenic 0.23-0.46% diet/12 mos.
Hypothermic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Insecticide Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Mutagenic
Perfumery Merck 11th Edition
OCTAN-3-OL Essential Oil-- -- Jim Duke's personal files.
ALPHA-YLANGENE Tissue Culture-- -- Jim Duke's personal files.
ESTRAGOLE Tissue Culture-- -- Jim Duke's personal files.
Activities (12)
Antiaggregant IC50=320 uMLaekeman, G.M., Van Hoof, L., Haemers, A., Vanden Berghe, D.A., Herman, A.G., and Vlietinck, A.J. Eugenol a Valuable Compound for In Vitro Experimental Research and Worthwhile for Further In Vivo Investigation. Phytotherapy Research 4(3): 93, 1990.
Calcium-Antagonist IC50=257.6 uM gpg
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Carcinogenic 4.4 uM/15 mos. scu mus
DNA-Binder Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
FLavor FEMA 4-150Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Hepatocarcinogenic 0.23-0.46% diet/12 mos.
Hypothermic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Insecticide Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Mutagenic
Perfumery Merck 11th Edition
BETA-BOURBONENE Shoot-- -- Jim Duke's personal files.
ALPHA-PINENE Essential Oil-- -- Jim Duke's personal files.
Activities (28)
Allelochemic
Allergenic
Antiacne
Antibacterial
Antifeedant
Antiflu Economic & Medicinal Plant Research, 5: 195.
Antiinflammatory 500 mg/kg
Antipneumonic
Antiseptic
Antispasmodic
Antistaphylococcic
Antiviral Economic & Medicinal Plant Research, 5: 195.
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Coleoptophile
Expectorant Michael Castleman 1991. The Healing Herbs. Rodale Press, Emmaus, PA 436 pp.
FLavor FEMA 15-150Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Herbicide IC50=30 uMKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Insecticide 0.82 uM/fly
Insectifuge 50 ppm
Insectiphile J. Stored. Prod. Res., 22:141, 1986.
Irritant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
P450-2B1-Inhibitor IC50=0.087 uM
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
Sedative Lawrence Review of Natural Products, Jun-90.
Spasmogenic
Tranquilizer Lawrence Review of Natural Products, Jun-90.
Transdermal
PARA-CYMENE Essential Oil-- -- Jim Duke's personal files.
AGASTACHIN Shoot-- 19.0 Jim Duke's personal files.
ALPHA-HUMULENE Shoot-- -- Jim Duke's personal files.
Activities (2)
Antitumor Zheng, G-Q., Kenney, P.M., and Lam, L.K.T. Sesquiterpenes From Clove (Eugenia caryophyllata) As Potential Anticarcinogenic Agents. Journal of Natural Products 55(7): 999-1003, 1992.
Perfumery Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
CARYOPHYLLENOL-I Shoot-- -- Jim Duke's personal files.
TILIANINE Shoot-- 46.0 Jim Duke's personal files.
ESSENTIAL OIL Plant-- -- Jim Duke's personal files.
ANISALDEHYDE Shoot-- -- Jim Duke's personal files.
Activities (7)
Antimutagenic Economic & Medicinal Plant Research, 6: 235.
Fungicide
Insecticide Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Pesticide
Tyrosinase-Inhibitor ID50=320 uM
Tyrosinase-Inhibitor ID50=0.32 mM
Tyrosinase-Inhibitor ID50=380-970 uM
ALPHA-PINENE Tissue Culture-- -- Jim Duke's personal files.
Activities (28)
Allelochemic
Allergenic
Antiacne
Antibacterial
Antifeedant
Antiflu Economic & Medicinal Plant Research, 5: 195.
Antiinflammatory 500 mg/kg
Antipneumonic
Antiseptic
Antispasmodic
Antistaphylococcic
Antiviral Economic & Medicinal Plant Research, 5: 195.
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Coleoptophile
Expectorant Michael Castleman 1991. The Healing Herbs. Rodale Press, Emmaus, PA 436 pp.
FLavor FEMA 15-150Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Herbicide IC50=30 uMKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Insecticide 0.82 uM/fly
Insectifuge 50 ppm
Insectiphile J. Stored. Prod. Res., 22:141, 1986.
Irritant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
P450-2B1-Inhibitor IC50=0.087 uM
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
Sedative Lawrence Review of Natural Products, Jun-90.
Spasmogenic
Tranquilizer Lawrence Review of Natural Products, Jun-90.
Transdermal
COSMOSIIN Leaf-- -- Jim Duke's personal files.
Activities (4)
Aldose-Reductase-Inhibitor IC40=1 uMShimizu, M., Ito, T., Terashima, S., Hayashi, T., Arisawa, M., Morita, N., Kurokawa, S., Ito, K., and Hashimoto, Y. 1984. Inhibition of Lens Aldose Reductase by Flavonoids. Phytochemistry, 23: 1885-1888.
Aldose-Reductase-Inhibitor IC99=10 uMShimizu, M., Ito, T., Terashima, S., Hayashi, T., Arisawa, M., Morita, N., Kurokawa, S., Ito, K., and Hashimoto, Y. 1984. Inhibition of Lens Aldose Reductase by Flavonoids. Phytochemistry, 23: 1885-1888.
Antibacterial MIC=500 ug/mlPlanta Medica, 57: A43, 1991.
Candidicide MIC=500 ug/mlPlanta Medica, 57: A43, 1991.
DIHYDROACTINIDIOLIDE Shoot-- -- Jim Duke's personal files.
HUMULENE Essential Oil-- -- Jim Duke's personal files.
Activities (2)
Antimalarial IC50=86 ug/ml
Antiplasmodial IC50=86 ug/ml
BETA-CARYOPHYLLENE Shoot-- -- Jim Duke's personal files.
TILIANIN Leaf-- -- Jim Duke's personal files.
ERYTHRODIOL-3-O-ACETATE Root-- -- Jim Duke's personal files.
ANISALDEHYDE Tissue Culture-- -- Jim Duke's personal files.
Activities (7)
Antimutagenic Economic & Medicinal Plant Research, 6: 235.
Fungicide
Insecticide Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Pesticide
Tyrosinase-Inhibitor ID50=320 uM
Tyrosinase-Inhibitor ID50=0.32 mM
Tyrosinase-Inhibitor ID50=380-970 uM
COSMOSIIN Inflorescence-- -- Jim Duke's personal files.
Activities (4)
Aldose-Reductase-Inhibitor IC40=1 uMShimizu, M., Ito, T., Terashima, S., Hayashi, T., Arisawa, M., Morita, N., Kurokawa, S., Ito, K., and Hashimoto, Y. 1984. Inhibition of Lens Aldose Reductase by Flavonoids. Phytochemistry, 23: 1885-1888.
Aldose-Reductase-Inhibitor IC99=10 uMShimizu, M., Ito, T., Terashima, S., Hayashi, T., Arisawa, M., Morita, N., Kurokawa, S., Ito, K., and Hashimoto, Y. 1984. Inhibition of Lens Aldose Reductase by Flavonoids. Phytochemistry, 23: 1885-1888.
Antibacterial MIC=500 ug/mlPlanta Medica, 57: A43, 1991.
Candidicide MIC=500 ug/mlPlanta Medica, 57: A43, 1991.
ACACETIN Leaf-- -- Jim Duke's personal files.
Activities (16)
Aldose-Reductase-Inhibitor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Allergenic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiaflatoxin IC50=7.25 uM
Antiaflatoxin IC50=2.06 ppm
Antiallergic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antihistaminic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antimalarial IC50=4.2-12.6 ug/ml
Antimutagenic Economic & Medicinal Plant Research, 6: 235.
Aromatase-Inhibitor IC12=1 uM/lJournal of Medicinal Food 2: 235.1999.
Hepatoprotective IC50=7.25 uM
Hepatoprotective IC50=2.06 ppm
Iodothyronine-Deiodinase-Inhibitor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Mutagenic
Plasmodicide IC50=4.2-12.6 ug/ml
Protisticide IC50=4.2-12.6 ug/ml
Topoisomerase-I-Inhibitor Santti, R., Makela, S., Strauss, L., Korman, J., Kostian, M. L. 1998. Phytoestrogens: Potential Endocrine Disruptors in Males. Toxicol Ind Health, 14: 223-237.
3-ALLYL-5-6-DIMETHOXY PHENOL Shoot-- -- Jim Duke's personal files.
HEX-1-EN-3-OL ACETATE Shoot-- -- Jim Duke's personal files.
CARYOPHYLLENE-OXIDE Shoot-- -- Jim Duke's personal files.
Activities (8)
Antiedemic Shimizu,*M., et al. 1990. Anti-inflammatory Constituents of Topically Applied Crude Drugs. IV.1) Constituents and Anti-inflammatory Effect of Paraguayan Crude Drug 'Alhucema' (Lavandula latifolia Vill.)2). Chem. Pharm. Bull. 38(8): 2283-2284, 1990.
Antifeedant Bettarini, F., Borgonovi, G.E., et al. 1991. Antiparasitic Compounds from East African Plants: Isolation and Biological Activity of Anonaine, Matricarianol, Canthin-6-One and Caryophyllene Oxide. Insect Sci. Applic. 14(1): 93-99, 1993.
Antiinflammatory Shimizu,*M., et al. 1990. Anti-inflammatory Constituents of Topically Applied Crude Drugs. IV.1) Constituents and Anti-inflammatory Effect of Paraguayan Crude Drug 'Alhucema' (Lavandula latifolia Vill.)2). Chem. Pharm. Bull. 38(8): 2283-2284, 1990.
Antitumor Zheng, G-Q., Kenney, P.M., and Lam, L.K.T. Sesquiterpenes From Clove (Eugenia caryophyllata) As Potential Anticarcinogenic Agents. Journal of Natural Products 55(7): 999-1003, 1992.
Calcium-Antagonist ED50=32 uM gpg
Fungicide
Insecticide Bettarini, F., Borgonovi, G.E., et al. 1991. Antiparasitic Compounds from East African Plants: Isolation and Biological Activity of Anonaine, Matricarianol, Canthin-6-One and Caryophyllene Oxide. Insect Sci. Applic. 14(1): 93-99, 1993.
Pesticide
TILIANIN Inflorescence-- -- Jim Duke's personal files.
BETA-ELEMENE Tissue Culture-- -- Jim Duke's personal files.
Activities (5)
Anticancer (Cervix) Medicinal and Poisonous Plants of the Tropics. Leeuwenberg, A.J.M., ed. Pudoc, Wageningen. 1987.
Antigliomic
Antiproliferant
Antitumor (Cervix) Medicinal and Poisonous Plants of the Tropics. Leeuwenberg, A.J.M., ed. Pudoc, Wageningen. 1987.
Apoptotic
ANISALDEHYDE Essential Oil-- 30000.0 1.0 Jim Duke's personal files.
Activities (7)
Antimutagenic Economic & Medicinal Plant Research, 6: 235.
Fungicide
Insecticide Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Pesticide
Tyrosinase-Inhibitor ID50=320 uM
Tyrosinase-Inhibitor ID50=0.32 mM
Tyrosinase-Inhibitor ID50=380-970 uM
OCT-1-EN-3-ONE Tissue Culture-- -- Jim Duke's personal files.
4-METHOXY-CINNAMIC ALCOHOL Shoot-- -- Jim Duke's personal files.
ACACETIN Inflorescence-- -- Jim Duke's personal files.
Activities (16)
Aldose-Reductase-Inhibitor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Allergenic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiaflatoxin IC50=7.25 uM
Antiaflatoxin IC50=2.06 ppm
Antiallergic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antihistaminic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antimalarial IC50=4.2-12.6 ug/ml
Antimutagenic Economic & Medicinal Plant Research, 6: 235.
Aromatase-Inhibitor IC12=1 uM/lJournal of Medicinal Food 2: 235.1999.
Hepatoprotective IC50=7.25 uM
Hepatoprotective IC50=2.06 ppm
Iodothyronine-Deiodinase-Inhibitor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Mutagenic
Plasmodicide IC50=4.2-12.6 ug/ml
Protisticide IC50=4.2-12.6 ug/ml
Topoisomerase-I-Inhibitor Santti, R., Makela, S., Strauss, L., Korman, J., Kostian, M. L. 1998. Phytoestrogens: Potential Endocrine Disruptors in Males. Toxicol Ind Health, 14: 223-237.
BETA OPLOPENTONE Shoot-- -- Jim Duke's personal files.
CARYOPHYLLA-4(14)-8(15)-DIEN-5-ALPHA-OL Shoot-- -- Jim Duke's personal files.
(-)-CARYOPHYLLENE Tissue Culture-- -- Jim Duke's personal files.
GERMACRENE-D Shoot-- -- Jim Duke's personal files.
Activities (2)
Pesticide
Pheromone
TILIANIN Root-- 84.0 Jim Duke's personal files.
BETA-ELEMENE Essential Oil-- -- Jim Duke's personal files.
Activities (5)
Anticancer (Cervix) Medicinal and Poisonous Plants of the Tropics. Leeuwenberg, A.J.M., ed. Pudoc, Wageningen. 1987.
Antigliomic
Antiproliferant
Antitumor (Cervix) Medicinal and Poisonous Plants of the Tropics. Leeuwenberg, A.J.M., ed. Pudoc, Wageningen. 1987.
Apoptotic
ANETHOLE Essential Oil-- 20000.0 -1.41 Jim Duke's personal files.
Activities (36)
Allergenic
AntiNF-kB
AntiTNF
Antibacterial MBC=200 ug/ml
Antigenotoxic 40-400 mg/kg orl mus
Antihepatotic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiinflammatory
Antioxidant
Antiradicular
Antisalmonella MIC=200 ug/ml
Antiseptic 200 ug/ml
Antispasmodic
Antitumor
Antiyeast
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidicide
Carminative Merck 11th Edition
Dermatitigenic
Digestive Michael Castleman 1991. The Healing Herbs. Rodale Press, Emmaus, PA 436 pp.
Estrogenic Australian J. Med Herbalism, 7: 29.
Expectorant Martindale's 29th
Fungicide Wolf, R.B. Effects Of p-Methoxycinnamaldehyde From Star Anise And Related Cinnamic Acid Derivatives On Velvetleaf Germination. Journal of Natural Products, 49(1): 156-158, 1986.
Gastrostimulant
Hepatotoxic 695 mg/kg orl mus/daysNewall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Immunostimulant Economic & Medicinal Plant Research, 1: 124.
Insecticide Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Irritant Rinzler, C. A. 1990. The Complete Book of Herbs, Spices and Condiments. Facts on File, New York. 199 pp.
Lactagogue
Leucocytogenic Economic & Medicinal Plant Research, 1: 124.
Mutagenic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Nephroprotective Toxicol Appl. Pharmacol. 1996.
Pesticide
Secretogogue Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Secretolytic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Sweetener 13 x sucrose
Sympathomimetic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
OCT-1-EN-3-OL ACETATE Shoot-- -- Jim Duke's personal files.
PARA-METHOXY CINNAMALDEHYDE Plant-- -- Jim Duke's personal files.
ACACETIN Root-- 6.8 Jim Duke's personal files.
Activities (16)
Aldose-Reductase-Inhibitor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Allergenic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiaflatoxin IC50=7.25 uM
Antiaflatoxin IC50=2.06 ppm
Antiallergic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antihistaminic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antimalarial IC50=4.2-12.6 ug/ml
Antimutagenic Economic & Medicinal Plant Research, 6: 235.
Aromatase-Inhibitor IC12=1 uM/lJournal of Medicinal Food 2: 235.1999.
Hepatoprotective IC50=7.25 uM
Hepatoprotective IC50=2.06 ppm
Iodothyronine-Deiodinase-Inhibitor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Mutagenic
Plasmodicide IC50=4.2-12.6 ug/ml
Protisticide IC50=4.2-12.6 ug/ml
Topoisomerase-I-Inhibitor Santti, R., Makela, S., Strauss, L., Korman, J., Kostian, M. L. 1998. Phytoestrogens: Potential Endocrine Disruptors in Males. Toxicol Ind Health, 14: 223-237.
OPLOPANONE Shoot-- -- Jim Duke's personal files.
TRANS-CARVEOL Shoot-- -- Jim Duke's personal files.
Activities (1)
Antiasthmatic
LINALOOL Tissue Culture-- -- Jim Duke's personal files.
Activities (53)
Acaricide C90=<15 ul/l (=<15 ppm
Allergenic
Analgesic
Anesthetic 0.01-1 ug/ml
Antiacetylcholinesterase
Antiallergic Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Antianaphylactic
Antibacterial MIC=1,600 ug/ml
Anticariogenic MIC=1,600 ug/mlMuroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105.
Anticolic
Anticonvulsant 200 mg/kg ipr mus
Antiedemic
Antiglutamaergic
Antihistaminic Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Antiinflammatory
Antileukemic IC50=3.5-4.2 ug/mlChiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antilymphomic IC50=3.5-4.2 ug/mlChiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antimange
Antimite
Antimutagenic
Antiseptic 5 x phenolWagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
Antishock Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Antispasmodic Buchbauer, G., Jirovetz*, L., Nikiforov, A., Remberg, G., Raverdino, V. 1989. Headspace-Analysis and Aroma Compounds of Austrian Hay-Blossoms (Flores Graminis, Graminis Flos) used in Aromatherapy. J. Ess. Oil Res., 2: 185-191, 1990.
Antiviral
Barbituate-Synergist
Bronchorelaxant Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
CNS-Depressant
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidistat
Carminative
Culicide LC50=156-194 mg/l
Cytotoxic
Expectorant Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
FLavor FEMA 2-40Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide Acta Botanica Sinica, 32: 49.
GABA-nergic
Hypnotic
Hypothermic
Insecticide LC50=156-194 mg/l
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Larvicide LC50=156-194 mg/l
Mosquitofuge > Deet
Motor-Depressant Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC
Nematicide MLC=1 mg/mlShoyakugaku Zasshi, 44: 183.
Perfumery Merck 11th Edition
Pesticide
Prooxidant Charalambous, G. (Ed.). 1994. Spices, Herbs and Edible Fungi. Elsevier Science B. V. Amsterdam. 764 pp.
Sedative ED=1-32 mg/kgWagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
Sedative 200 mg/kg ipr mus (1% as active as diazepam)
Termitifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Trichomonicide LD100=600 ug/ml
Tumor-Promoter
BETA-FARNESENE Tissue Culture-- -- Jim Duke's personal files.
SPATHULENOL Shoot-- -- Jim Duke's personal files.
DIOSMETIN-7-O-BETA-D-GLUCOSIDE Leaf-- -- Jim Duke's personal files.
ANETHOLE Tissue Culture-- -- Jim Duke's personal files.
Activities (36)
Allergenic
AntiNF-kB
AntiTNF
Antibacterial MBC=200 ug/ml
Antigenotoxic 40-400 mg/kg orl mus
Antihepatotic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiinflammatory
Antioxidant
Antiradicular
Antisalmonella MIC=200 ug/ml
Antiseptic 200 ug/ml
Antispasmodic
Antitumor
Antiyeast
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidicide
Carminative Merck 11th Edition
Dermatitigenic
Digestive Michael Castleman 1991. The Healing Herbs. Rodale Press, Emmaus, PA 436 pp.
Estrogenic Australian J. Med Herbalism, 7: 29.
Expectorant Martindale's 29th
Fungicide Wolf, R.B. Effects Of p-Methoxycinnamaldehyde From Star Anise And Related Cinnamic Acid Derivatives On Velvetleaf Germination. Journal of Natural Products, 49(1): 156-158, 1986.
Gastrostimulant
Hepatotoxic 695 mg/kg orl mus/daysNewall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Immunostimulant Economic & Medicinal Plant Research, 1: 124.
Insecticide Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Irritant Rinzler, C. A. 1990. The Complete Book of Herbs, Spices and Condiments. Facts on File, New York. 199 pp.
Lactagogue
Leucocytogenic Economic & Medicinal Plant Research, 1: 124.
Mutagenic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Nephroprotective Toxicol Appl. Pharmacol. 1996.
Pesticide
Secretogogue Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Secretolytic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Sweetener 13 x sucrose
Sympathomimetic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
OCT-1-EN-3-OL Essential Oil-- -- Jim Duke's personal files.
PARA-METHOXY CINNAMALDEHYDE Tissue Culture-- -- Jim Duke's personal files.
ACACETIN Shoot-- 285.0 Jim Duke's personal files.
Activities (16)
Aldose-Reductase-Inhibitor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Allergenic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiaflatoxin IC50=7.25 uM
Antiaflatoxin IC50=2.06 ppm
Antiallergic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antihistaminic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antimalarial IC50=4.2-12.6 ug/ml
Antimutagenic Economic & Medicinal Plant Research, 6: 235.
Aromatase-Inhibitor IC12=1 uM/lJournal of Medicinal Food 2: 235.1999.
Hepatoprotective IC50=7.25 uM
Hepatoprotective IC50=2.06 ppm
Iodothyronine-Deiodinase-Inhibitor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Mutagenic
Plasmodicide IC50=4.2-12.6 ug/ml
Protisticide IC50=4.2-12.6 ug/ml
Topoisomerase-I-Inhibitor Santti, R., Makela, S., Strauss, L., Korman, J., Kostian, M. L. 1998. Phytoestrogens: Potential Endocrine Disruptors in Males. Toxicol Ind Health, 14: 223-237.
3-O-ACETYL-OLEANOLIC ALDEHYDE Root-- 4.4 Jim Duke's personal files.
CIS-CARVEOL Shoot-- -- Jim Duke's personal files.
LINALOOL Essential Oil-- -- Jim Duke's personal files.
Activities (53)
Acaricide C90=<15 ul/l (=<15 ppm
Allergenic
Analgesic
Anesthetic 0.01-1 ug/ml
Antiacetylcholinesterase
Antiallergic Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Antianaphylactic
Antibacterial MIC=1,600 ug/ml
Anticariogenic MIC=1,600 ug/mlMuroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105.
Anticolic
Anticonvulsant 200 mg/kg ipr mus
Antiedemic
Antiglutamaergic
Antihistaminic Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Antiinflammatory
Antileukemic IC50=3.5-4.2 ug/mlChiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antilymphomic IC50=3.5-4.2 ug/mlChiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antimange
Antimite
Antimutagenic
Antiseptic 5 x phenolWagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
Antishock Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Antispasmodic Buchbauer, G., Jirovetz*, L., Nikiforov, A., Remberg, G., Raverdino, V. 1989. Headspace-Analysis and Aroma Compounds of Austrian Hay-Blossoms (Flores Graminis, Graminis Flos) used in Aromatherapy. J. Ess. Oil Res., 2: 185-191, 1990.
Antiviral
Barbituate-Synergist
Bronchorelaxant Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
CNS-Depressant
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidistat
Carminative
Culicide LC50=156-194 mg/l
Cytotoxic
Expectorant Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
FLavor FEMA 2-40Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide Acta Botanica Sinica, 32: 49.
GABA-nergic
Hypnotic
Hypothermic
Insecticide LC50=156-194 mg/l
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Larvicide LC50=156-194 mg/l
Mosquitofuge > Deet
Motor-Depressant Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC
Nematicide MLC=1 mg/mlShoyakugaku Zasshi, 44: 183.
Perfumery Merck 11th Edition
Pesticide
Prooxidant Charalambous, G. (Ed.). 1994. Spices, Herbs and Edible Fungi. Elsevier Science B. V. Amsterdam. 764 pp.
Sedative ED=1-32 mg/kgWagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
Sedative 200 mg/kg ipr mus (1% as active as diazepam)
Termitifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Trichomonicide LD100=600 ug/ml
Tumor-Promoter
EUGENOL-METHYL-ETHER Shoot-- -- Jim Duke's personal files.
Activities (5)
CNS-Depressant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
DNA-Binder Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Hypothermic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Myorelaxant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
BETA-SITOSTEROL Root-- -- Jim Duke's personal files.
Activities (47)
Androgenic
Angiogenic
Anorexic Martindale's 28th
Antiadenomic Merck 11th Edition
Antiandrogenic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antibacterial Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155.
Anticancer (Breast) Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103.
Anticancer (Cervix)
Anticancer (Lung)
Antiedemic IC54=320 mg/kg orl
Antiestrogenic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antifeedant Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Antifertility Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antigonadotrophic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antihyperlipoproteinaemic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiinflammatory
Antileukemic
Antilymphomic
Antimutagenic 250 ug/ml
Antiophidic 2.3 mg musEconomic & Medicinal Plant Research, 5: 363.
Antioxidant IC44=10 uM
Antiprogestational Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antiprostaglandin 30 mg/day/12 wks
Antiprostatadenomic Merck 11th Edition
Antiprostatitic 10-20 mg 3 x/day/orl man
Antipyretic Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
Antitumor (Breast) Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103.
Antitumor (Cervix)
Antitumor (Lung)
Antiviral Abid Ali Khan, M.M., Jain, D.C., Bhakuni, R.S., Zaim, M., and Thakur, R.S. 1991. Occurrence of some antiviral sterols in Artemisia annua. Plant Science, 75: 161-165, 1991.
Apoptotic
Artemicide LC50=110 ppmJung, J.H., Pummangura, S., Chaichantipyuth, c., Patarapanich, C., and McLaughlin, J.L. 1989. Bioactive Constituents of Melodorum fruticosum. Phytochemistry. 29(5): 1667-1670. 1990.
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidicide Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155.
Caspase-8-Inducer
Estrogenic
Febrifuge Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
Gonadotrophic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Hepatoprotective
Hypocholesterolemic 2-6 g/man/day/orlMartindale's 30th
Hypocholesterolemic 9-3,330 mg/man/day/orlMartindale's 28th
Hypoglycemic Ivorra, M.D., Paya, M., and Villar, A. 1989. A Review of Natural Products and Plants as Potential Antidiabetic Drugs. Journal of Ethnopharmacology, 27: 243-275, 1989.
Hypolipidemic 2-6 g/day
Pesticide
Spermicide Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Ubiquiot Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Ulcerogenic 500 mg/kg ipr rat
DIOSMETIN-7-O-BETA-D-GLUCOSIDE Inflorescence-- -- Jim Duke's personal files.
DEHYDRO-AGASTOL Root-- 6.4 Jim Duke's personal files.
D-LIMONENE Essential Oil-- 50000.0 1.11 Jim Duke's personal files.
Activities (19)
Antiacetylcholinesterase IC22=1.2 mM
Anticancer (Breast) 8,000 mg/kg
Anticancer (Gastric)
Antimelanomic IC50=450 uM/l
Antitumor (Breast) 8,000 mg/kg
Antitumor (Gastric)
Antitumor-Promoter
Apoptotic 8,000 mg/kg
Cancer-Preventive
Chemopreventive
Differentiator 8,000 mg/kg
FLavor FEMA 30-2,300Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Hypocholesterolemic
Insecticide
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Litholytic Martindale's 28th
Nephrotoxic
P450-2B1-Inhibitor IC50=0.19 uM
Pesticide
PARA-METHOXY CINNAMALDEHYDE Essential Oil-- 10000.0 Jim Duke's personal files.
ABIETA-4(18)-8-11-13-TETRAEN-7-ONE Root-- 26.6 Jim Duke's personal files.
3-O-ACETYL-OLEANOLIC ALDEHYDE Plant-- -- Jim Duke's personal files.
CALAMENE Tissue Culture-- -- Jim Duke's personal files.
LINALOOL Shoot-- -- Jim Duke's personal files.
Activities (53)
Acaricide C90=<15 ul/l (=<15 ppm
Allergenic
Analgesic
Anesthetic 0.01-1 ug/ml
Antiacetylcholinesterase
Antiallergic Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Antianaphylactic
Antibacterial MIC=1,600 ug/ml
Anticariogenic MIC=1,600 ug/mlMuroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105.
Anticolic
Anticonvulsant 200 mg/kg ipr mus
Antiedemic
Antiglutamaergic
Antihistaminic Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Antiinflammatory
Antileukemic IC50=3.5-4.2 ug/mlChiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antilymphomic IC50=3.5-4.2 ug/mlChiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antimange
Antimite
Antimutagenic
Antiseptic 5 x phenolWagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
Antishock Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Antispasmodic Buchbauer, G., Jirovetz*, L., Nikiforov, A., Remberg, G., Raverdino, V. 1989. Headspace-Analysis and Aroma Compounds of Austrian Hay-Blossoms (Flores Graminis, Graminis Flos) used in Aromatherapy. J. Ess. Oil Res., 2: 185-191, 1990.
Antiviral
Barbituate-Synergist
Bronchorelaxant Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
CNS-Depressant
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidistat
Carminative
Culicide LC50=156-194 mg/l
Cytotoxic
Expectorant Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
FLavor FEMA 2-40Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide Acta Botanica Sinica, 32: 49.
GABA-nergic
Hypnotic
Hypothermic
Insecticide LC50=156-194 mg/l
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Larvicide LC50=156-194 mg/l
Mosquitofuge > Deet
Motor-Depressant Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC
Nematicide MLC=1 mg/mlShoyakugaku Zasshi, 44: 183.
Perfumery Merck 11th Edition
Pesticide
Prooxidant Charalambous, G. (Ed.). 1994. Spices, Herbs and Edible Fungi. Elsevier Science B. V. Amsterdam. 764 pp.
Sedative ED=1-32 mg/kgWagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
Sedative 200 mg/kg ipr mus (1% as active as diazepam)
Termitifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Trichomonicide LD100=600 ug/ml
Tumor-Promoter
EUGENOL-METHYL-ETHER Essential Oil-- -- Jim Duke's personal files.
Activities (5)
CNS-Depressant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
DNA-Binder Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Hypothermic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Myorelaxant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
SAFROLE Essential Oil-- -- Jim Duke's personal files.
Activities (29)
Anesthetic
Antiaggregant IC50=110 uMJanssens, J., Laekeman, G.M., Pieters, L.A.C., Totte, J., Herman, A.G., and Vlietinck, A.J. 1990. Nutmeg Oil: Identification and Quantitation of its Most Active Constituents as Inhibitors of Platelet Aggregation. J.of Ethnopharmacology, 29: 179-188, 1990.
Antibacterial
Anticonvulsant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiseptic Merck 11th Edition
CNS-Depressant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
CNS-Stimulant List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Calcium-Antagonist IC50=58 uM
Calcium-Antagonist IC50=57 uM gpg
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Carcinogenic Merck 11th Edition
Carminative
Controlled HerbalGram No. 20, page 15.
Cytochrome-P450-Inducer Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Cytochrome-P488-Inducer Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
DNA-Binder Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Hepatocarcinogenic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Hepatoregenerative CRC Handbook of Medicinal Herbs and/or CRC Handbook of Proximate Analyses
Hepatotoxic Martindale's 29th
Hypothermic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Irritant Rinzler, C. A. 1990. The Complete Book of Herbs, Spices and Condiments. Facts on File, New York. 199 pp.
Mutagenic
Nematicide MLC=1 mg/mlShoyakugaku Zasshi, 44: 183.
Neurotoxic R.J. Hixtable (Huxtable, R.J. (as T. Max). 1992. This and That:The Essential Pharmacology of Herbs and Spices. Tips 13:15-20 Huxtable, R.J. 1992b. The Myth of Benficent Nature. The Risk of Herbal Preparations. Anns. Intern. Med. 117(2):165-6; Huxtable, R.
Pediculicide Merck 11th Edition
Perfumery Merck 11th Edition
Pesticide
Psychoactive R.J. Hixtable (Huxtable, R.J. (as T. Max). 1992. This and That:The Essential Pharmacology of Herbs and Spices. Tips 13:15-20 Huxtable, R.J. 1992b. The Myth of Benficent Nature. The Risk of Herbal Preparations. Anns. Intern. Med. 117(2):165-6; Huxtable, R.
Tremorigenic
DAUCOSTEROL Root-- 5.2 -0.54 Jim Duke's personal files.
Activities (5)
Aldose-Reductase-Inhibitor 0.1 mM/l rat (weak activity, 31.9% inhibition)Fujita, T., Ohira, K., Miyatake, K., Nakano, Y., Nakayama, M. 1995. Inhibitory Effect of Perillosides A and C, Related Monoterpene Glucosides on Aldose Reductase and Their Structure-Activity Relationships. Chem Pharm Bull, 43(6): 920-926.
Antileukemic
Antispasmodic 20 mg/kg=ICMR(Indian Council of Medical Research).1976.Medicinal Plants of India.Vol.1.Indian Council of Med. Res.Cambridge Printing Works, New Delhi.487 pp;ICMR.1987.Medicinal Plants of India.Vol.2.Indian Council of Med. Res.Cambr. Printing Works,New Delhi.600pp
Antitumor
Hypoglycemic Economic & Medicinal Plant Research, 6: 158.
AGASTANOL Root-- 35.5 Jim Duke's personal files.
ALPHA-LIMONENE Tissue Culture-- -- Jim Duke's personal files.
4-METHOXYCINNAMALDEHYDE Shoot-- -- Jim Duke's personal files.
PACHYPODOL Leaf-- -- Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Activities (2)
Antiviral Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
OLEANOLIC-ACID Root-- 10.0 -0.86 Jim Duke's personal files.
Activities (64)
Abortifacient
AntiHIV IC50=21.8 ug/ml
AntiHIV EC50=1.7 ug/mlKashiwada, Y., et. al. 1998. Anti-AIDS Agents. 30. Anti-HIV Activity of Oleanolic Acid, Pomolic Acid, and Structurally Related Triterpenoids. J. Nat. Prod., 61 (9): 1090-1095.
AntiPGE2 IC50=24 uM
AntiTGF-beta IC50=19-24 uM
Antiallergic
Antiarrhythmic 40 mg/kg
Antiatherosclerotic
Antibacterial MIC=625-1,250 ug/ml
Anticarcinomic Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Anticariogenic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Anticomplement IC40-50 0.01 mM/l gpgHansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
Anticomplement IC80-90 0.05 mM/l gpgHansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
Antiedemic IC36=40 mg/kg ipr rat
Antifertility
Antigingivitic MIC=625-1,250 ug/ml
Antihepatotoxic
Antihyperlipidemic
Antiinflammatory 40 mg/kg iprAquino, R., De Feo, V., De Simone, F., Pizza, C.*, and Cirino, G. Plant Metabolites. New Compounds And Anti-Inflammatory Activity Of Uncaria tomentosa. Journal of Natural Products, 54(2): 453-459, 1991.
Antiischemic 40 mg/kg
Antileukemic Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antileukotriene IC50=17 uM
Antimalarial IC50=70-89 ug/ml
Antinephritic IC50=19-24 uM
Antioxidant Balanehru, S. and Nagarajan, B. 1992. Intervention of Adriamycin Induced Free Radical Damage. Biochemistry International 28(4): 735-744, 1992.
Antioxidant IC46=10 uM
Antiperiodontic MIC=625-1,250 ug/ml
Antiperoxidant IC30=200 ug/ml
Antiplaque MIC=625-1,250 ug/ml
Antiplasmodial IC50=70-89 ug/ml
Antisarcomic
Antiseptic MIC=625-1,250 ug/ml
Antitumor
Antitumor (Breast) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor (Colon) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor (Kidney) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor (Lung) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor (Pancreas) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antiulcer >carbenoxolone
Antiviral EC50=1.7 ug/mlKashiwada, Y., et. al. 1998. Anti-AIDS Agents. 30. Anti-HIV Activity of Oleanolic Acid, Pomolic Acid, and Structurally Related Triterpenoids. J. Nat. Prod., 61 (9): 1090-1095.
Antiviral IC50=21.8 ug/mlKashiwada, Y., et. al. 1998. Anti-AIDS Agents. 30. Anti-HIV Activity of Oleanolic Acid, Pomolic Acid, and Structurally Related Triterpenoids. J. Nat. Prod., 61 (9): 1090-1095.
Aromatase-Inhibitor
Beta-Blocker
Beta-Glucuronidase-Inhibitor ~100 mg/kg
COX-2-Inhibitor IC50=295 uM/
COX-2-Inhibitor Ringbom, T., Seguar, L., Noreen, Y., Perera, P., Bohlin, L. 1998. Ursolic Acid from Plantago major, a Selective Inhibitor of Cyclooxygenase-2 Catalyzed Prostaglandin Biosynthesis. J. Nat. Prod., 61(10): 1212-1215.
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Cardioprotective 40 mg/kg
Cardiotonic
Cyclooxygenase-Inhibitor
Diuretic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Elastase-Inhibitor IC50=~15 uM
Hepatoprotective Advance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 211.
Hypolipemic
Hypotensive
Immunomodulator
Leucocytogenic
NF-kB-Inhibitor
Phagocytotic
Piscicide ANON. 1948-1976. The Wealth of India raw materials. Publications and Information Directorate, CSIR, New Delhi. 11 volumes.
Prostaglandin-Synthesis-Inhibitor igs mus
Sedative
Uterotonic
Vasopressor
ALPHA-CADINOL Shoot-- -- Jim Duke's personal files.
Activities (3)
Acaricide
Antimite
Pesticide
LIMONENE Essential Oil-- -- Jim Duke's personal files.
Activities (60)
AChE-Inhibitor Grundy, D. L. and Still, C. C., Inhibition of acetylcholinesterases by pulegone-1,2-epoxide, Oest. Biochem. & Physiol., 23, 1985, 383-8.
Acaricide LC100=8 uM
Allelochemic
Allergenic 1/20th carene
Antiacetylcholinesterase IC22-26=1.2 mM
Antiadenomic
Antialzheimeran? Grundy, D. L. and Still, C. C., Inhibition of acetylcholinesterases by pulegone-1,2-epoxide, Oest. Biochem. & Physiol., 23, 1985, 383-8.
Antiasthmatic
Antibacterial Revista Itiliana Eppos, 12: 5, 1994.
Anticancer
Antiesophagitic
Antifeedant
Antiflu Economic & Medicinal Plant Research, 5: 195.
Antiinflammatory
Antilithic
Antilymphomic
Antimetastatic (Stomach)
Antimutagenic Economic & Medicinal Plant Research, 6: 235.
Antiobesity
Antiseptic
Antispasmodic ED50=0.197 mg/mlFitoterapia No.59-1984.
Antitumor
Antitumor (Breast)
Antitumor (Colon)
Antitumor (Pancreas)
Antitumor (Prostate)
Antitumor (Stomach)
Antiviral
Apoptotic
Bronchoprotectant
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidistat
Chemopreventive
Cholesterolytic
Detoxicant
Enterocontractant J. Aromatherapy 4: 22.
Expectorant
FLavor
Fungiphilic J. Agric. Food Chem. 43: 2283.
Fungistat
GST-Inducer
Herbicide IC50=45 uMKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Histaminic
Immunomodulator
Insecticide 0.37 uM/fly
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Interleukin-6-Inhibitor
Irritant
Lipolytic
Myorelaxant 50 mg/kg
NO-Genic
Nematicide IC=100 ug/mlNigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Ornithine-Decarboxylase-Inhibitor ~750 mg/kg (diet)
Ozone-Scavenger
P450-Inducer
Peristaltic
Pesticide
Photosensitizer Rinzler, C. A. 1990. The Complete Book of Herbs, Spices and Condiments. Facts on File, New York. 199 pp.
Sedative ED=1-32 mg/kgWagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
Transdermal
EUGENOL Shoot-- -- Jim Duke's personal files.
Activities (76)
Acaricide LD50=5.47 ug/sq cm cf DEET at 37.59 ug/sq cm
Allergenic
Analgesic Merck 11th Edition
Anesthetic 200-400Phytotherapy Research, 4: 93.
AntiTNF
Antiaggregant IC50=0.3 uMPhytotherapy Research, 4: 93.
Antiarachidonate
Antibacterial 500 ppmValnet, J. 1982. The Practice of Aromatherapy. Translated from the 1980 French Edition by Robin Campbell and Libby Houston. Destiny Books, New York. 279 pp.
Antibacterial MBC=400 ug/ml
Anticonvulsant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiedemic 100Phytotherapy Research, 4: 95.
Antiestrogenic
Antifeedant Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Antigenotoxic 50-500 mg/kg orl mus
Antiherpetic IC50=16.2-25.6 ug/ml
Antiinflammatory (11 uM) IC~97=1,000 uM
Antikeratotic IC50=16.2-25.6 ug/ml
Antimitotic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antimutagenic Economic & Medicinal Plant Research, 6: 235.
Antinitrosating
Antioxidant IC65=30 ppm
Antioxidant 10 uM
Antiprostaglandin 11 uM
Antiprostaglandin IC50=9.2 mM
Antipyretic 3 ml/man/day
Antiradicular EC50=2 ul/l
Antisalmonella MIC=400 ug/ml
Antiseptic 3 ml/man/day
Antiseptic 400 ug/ml
Antispasmodic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Antistaphylococcic Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands.
Antithromboxane Lawrence Review of Natural Products, Jul-87.
Antitumor Zheng, G-Q., Kenney, P.M., and Lam, L.K.T. Sesquiterpenes From Clove (Eugenia caryophyllata) As Potential Anticarcinogenic Agents. Journal of Natural Products 55(7): 999-1003, 1992.
Antiulcer
Antiviral IC50=16.2-25.6 ug/ml
Apifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
CNS-Depressant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
COX-1-Inhibitor IC97=1,000 uM
COX-2-Inhibitor IC>97=1,000 uM
COX-2-Inhibitor IC50=129 uM
Calcium-Antagonist IC50=224 uM
Calcium-Antagonist IC50=200 uM gpg
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidicide Phytotherapy Research, 4: 93.
Carcinogenic? Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Carminative Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994.
Choleretic
Cytochrome-P450-Inhibitor Pizzorno, J. 1998. Total Wellness. Prima Health, a division of Prima.
Cytotoxic 25 ug/mlPhytotherapy Research, 4: 93.
Dermatitigenic
Enterorelaxant J. Aromatherapy 4: 22.
FLavor FEMA 10-500Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide
Hepatoprotective 100 ppm
Herbicide
Insecticide
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Irritant
Juvabional Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Larvicide
Motor-Depressant Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC
Nematicide MLC=2,000 ug/mlShoyakugaku Zasshi, 44: 183.
Neurotoxic R.J. Hixtable (Huxtable, R.J. (as T. Max). 1992. This and That:The Essential Pharmacology of Herbs and Spices. Tips 13:15-20 Huxtable, R.J. 1992b. The Myth of Benficent Nature. The Risk of Herbal Preparations. Anns. Intern. Med. 117(2):165-6; Huxtable, R.
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
Prostaglandin-Synthesis-Inhibitor 1 mM rbtChen, S. J., Wang, M. H., Chen, I. J. 1996. Antiplatelet and Calcium Inhibitory Properties of Eugenol and Sodium Eugenol Acetate. Gen Pharmacol, 27(4): 629-633.
Prostaglandin-Synthesis-Inhibitor IC50=9.2 uM
Sedative
Termiticide LD100=5 mg/g
Trichomonicide LD100=300 ug/ml
Trichomonistat IC50=10 ug/mlNigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Trypsin-Enhancer Lawrence Review of Natural Products, Dec-93.
Ulcerogenic Phytotherapy Research, 4: 93.
Varroacide
Vasodilator
Vermifuge
ROSMARINIC-ACID Leaf-- 9000.0 0.19 Jim Duke's personal files.
Activities (57)
ABeta-Inhibitor
Adenylate-Cyclase-Inhibitor
Aldose-Reductase-Inhibitor
AntiHIV EC50=40 ug/ml
Antiaggregant Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Antiallergic
Antialzheimeran
Antianaphylactic 1-100 mg/kg orlInt. J. Immunopharmacology. Vol 10: 729, 1988.
Antianaphylactic ID50=1 mg/kg ivn rat
Antianaphylactic ID50=10 mg/kg ims rat
Antiatherosclerotic IC50=0.74 uM
Antibacterial Planta Medica, 55: 663.
Anticoagulant Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Anticomplementary 1/2 aspirin
Anticomplementary 20 mg/kg ivnNewall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Antidepressant
Antiedemic 0.316-3.16 mg/kg imsInt. J. Immunopharmacology. Vol 10: 729, 1988.
Antigonadotropic
Antihemolytic IC70=5-10 um/lInt. J. Immunopharmacology. Vol 10: 729, 1988.
Antihepatotoxic
Antiherpetic 50 ug/mlVlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
Antiherpetic EC50=20 ug/ml
Antihyperthyroid
Antiinflammatory IC~58=1,000 uM
Antiintegrase 10 ug/ml
Antileukotriene
Antilipoperoxidant
Antimutagenic
Antinephritic
Antioxidant EC50=2.7 ug/mlParveen, N. 1991. Antifilarial Activity of Vitex negundo Against Setaria cervi. Fitoterapia, 62(2): 163, 1991.
Antioxidant 10 uM
Antioxidant (LDL) IC50=0.74 uM
Antiplaque
Antiproliferant
Antiprostaglandin 20 mg/kg ivnNewall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Antiproteolytic IC50=0.9 mol lHansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
Antipulmonotic Tyler, V.E.. 1994.
Antiradicular
Antishock Int. J. Immunopharmacology. Vol 10: 735, 1988.
Antithyreotropic
Antithyroid Jim Duke's personal files.
Antiuremic
Antiviral EC50=40 ug/ml
Anxiolytic
Apoptotic
COX-1-Inhibitor IC58=1,000 uM
COX-2-Inhibitor IC>58=1,000 uM
Calcium-Antagonist IC50=1.2 uM rbt
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Cytotoxic TC50=100-150 ug/ml
Deiodinase-Inhibitor Jim Duke's personal files.
Immunomodulator
Immunostimulant
Lipoxygenase-Inhibitor
Neuroprotective
Pesticide
Radioprotective
CYNAROSIDE Leaf-- -- Jim Duke's personal files.
Activities (3)
Aldose-Reductase-Inhibitor IC50=0.99 uM rat (strong activity)Yoshikawa, M., et al. 1999. Medicinal Flowers. I. Aldose Reductase Inhibitors and Three New Eudesmane-Type Sesquiterpenes, Kikkanols A, B, and C, From the Flowers of Chrysanthemum inducum L. Chem Pharm Bull, 47(3): 340-345.
Calcium-Antagonist IC50=1.2 uM rbt
Hypocholesterolemic
ISO-AGASTACHOSIDE Shoot-- 210.0 Jim Duke's personal files.
TRANS-JASMONE Shoot-- -- Jim Duke's personal files.
CHAVICOL Shoot-- -- Jim Duke's personal files.
Activities (3)
Fungicide
Nematicide HerbalGram No. 17.
Pesticide
P-METHOXYCINNAMALDEHYDE Shoot-- -- Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Activities (2)
Herbicide 5 mM
Pesticide
OCTAN-3-ONE Tissue Culture-- -- Jim Duke's personal files.
CARYOPHYLLENE Essential Oil-- -- Jim Duke's personal files.
Activities (31)
Aldose-Reductase-Inhibitor
Allergenic
Analgesic Taylor, Leslie. 2005. The Healing Power of Rainforest Herbs. SquareOne Publisher, Garden City Park, NY. 519 pp.
Antiacne
Antiasthmatic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Antibacterial
Anticariogenic MIC=>1,600 ug/mlMuroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105.
Antidermatitic
Antiedemic Shimizu,*M., et al. 1990. Anti-inflammatory Constituents of Topically Applied Crude Drugs. IV.1) Constituents and Anti-inflammatory Effect of Paraguayan Crude Drug 'Alhucema' (Lavandula latifolia Vill.)2). Chem. Pharm. Bull. 38(8): 2283-2284, 1990.
Antifeedant 500 ppmKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Antiinflammatory IC50=100 uMShimizu,*M., et al. 1990. Anti-inflammatory Constituents of Topically Applied Crude Drugs. IV.1) Constituents and Anti-inflammatory Effect of Paraguayan Crude Drug 'Alhucema' (Lavandula latifolia Vill.)2). Chem. Pharm. Bull. 38(8): 2283-2284, 1990.
Antileishmanic
Antionychyotic Taylor, Leslie. 2005. The Healing Power of Rainforest Herbs. SquareOne Publisher, Garden City Park, NY. 519 pp.
Antiproliferant
Antispasmodic
Antistaphylococcic
Antistreptococcic
Antitumor Zheng, G-Q., Kenney, P.M., and Lam, L.K.T. Sesquiterpenes From Clove (Eugenia caryophyllata) As Potential Anticarcinogenic Agents. Journal of Natural Products 55(7): 999-1003, 1992.
Antiulcer Taylor, Leslie. 2005. The Healing Power of Rainforest Herbs. SquareOne Publisher, Garden City Park, NY. 519 pp.
Candidicide
FLavor FEMA 20-200Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide
Gastroprotective Taylor, Leslie. 2005. The Healing Power of Rainforest Herbs. SquareOne Publisher, Garden City Park, NY. 519 pp.
Insectifuge
Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Larvicide
Mosquitocide
Perfumery Merck 11th Edition
Pesticide
Sedative
Termitifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
ESTRAGOLE Shoot-- -- Jim Duke's personal files.
Activities (12)
Antiaggregant IC50=320 uMLaekeman, G.M., Van Hoof, L., Haemers, A., Vanden Berghe, D.A., Herman, A.G., and Vlietinck, A.J. Eugenol a Valuable Compound for In Vitro Experimental Research and Worthwhile for Further In Vivo Investigation. Phytotherapy Research 4(3): 93, 1990.
Calcium-Antagonist IC50=257.6 uM gpg
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Carcinogenic 4.4 uM/15 mos. scu mus
DNA-Binder Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
FLavor FEMA 4-150Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Hepatocarcinogenic 0.23-0.46% diet/12 mos.
Hypothermic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Insecticide Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Mutagenic
Perfumery Merck 11th Edition
GAMMA-CADINENE Tissue Culture-- -- Jim Duke's personal files.
BETA-PINENE Essential Oil-- -- Jim Duke's personal files.
Activities (13)
Allergenic
Antiinflammatory
Antiseptic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Antispasmodic
Candidicide
FLavor FEMA 15-600Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Herbicide Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
Spasmogenic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Transdermal
CYNAROSIDE Inflorescence-- -- Jim Duke's personal files.
Activities (3)
Aldose-Reductase-Inhibitor IC50=0.99 uM rat (strong activity)Yoshikawa, M., et al. 1999. Medicinal Flowers. I. Aldose Reductase Inhibitors and Three New Eudesmane-Type Sesquiterpenes, Kikkanols A, B, and C, From the Flowers of Chrysanthemum inducum L. Chem Pharm Bull, 47(3): 340-345.
Calcium-Antagonist IC50=1.2 uM rbt
Hypocholesterolemic
AGASTACHOSIDE Root-- 9.2 Jim Duke's personal files.
CIS-JASMONE Shoot-- -- Jim Duke's personal files.
CHAVIBETOL Shoot-- -- Jim Duke's personal files.
P-ANISALDEHYDE Plant-- -- Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Activities (11)
Antimutagenic Economic & Medicinal Plant Research, 6: 235.
Cosmetic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
FLavor FEMA 0.5-75Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Insecticide Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Nematicide MLC=1 mg/mlShoyakugaku Zasshi, 44: 183.
Perfumery Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
Piscicide Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
Sedative Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
OCTAN-3-OL Tissue Culture-- -- Jim Duke's personal files.
MASLINIC-ACID Root-- 12.4 Jim Duke's personal files.
Activities (6)
AntiHIV IC100=18 ug/ml
Antiedemic
Antihistaminic
Antiinflammatory Chem & Pharm. Bull., 34: 2164, 1986.
Antiviral IC100=18 ug/ml
Protease-Inhibitor IC100=18 ug/ml
ESTRAGOLE Essential Oil-- 895000.0 0.78 Jim Duke's personal files.
Activities (12)
Antiaggregant IC50=320 uMLaekeman, G.M., Van Hoof, L., Haemers, A., Vanden Berghe, D.A., Herman, A.G., and Vlietinck, A.J. Eugenol a Valuable Compound for In Vitro Experimental Research and Worthwhile for Further In Vivo Investigation. Phytotherapy Research 4(3): 93, 1990.
Calcium-Antagonist IC50=257.6 uM gpg
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Carcinogenic 4.4 uM/15 mos. scu mus
DNA-Binder Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
FLavor FEMA 4-150Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Hepatocarcinogenic 0.23-0.46% diet/12 mos.
Hypothermic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Insecticide Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Mutagenic
Perfumery Merck 11th Edition
DELTA-CADINENE Essential Oil-- -- Jim Duke's personal files.
Activities (9)
Aldose-Reductase-Inhibitor
Antiacne
Antibacterial MIC800 ug/mlMuroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105.
Anticariogenic MIC800 ug/mlMuroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105.
Antistreptococcic
Cytochrome-P450-Inducer
P450-Inducer
Pesticide
Testosterone-Inducer
*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.